Browsing by Author "Koc, DO"

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    Acute pancreatitis in Turkey: Results of a nationwide multicenter study
    Koksal, AS; Tozlu, M; Sezgin, O; Oguz, D; Kalkan, IH; Altntas, E; Yaras, S; Bilgic, Y; Yildirim, AE; Barutcu, S; Hakim, GD; Soytuerk, M; Bengi, G; Ozseker, B; Yurci, A; Koc, DO; Irak, K; Kasap, E; Cindoruk, M; Oruc, N; Ünal, NG; Sen, I; Gokden, Y; Saruc, M; Ünal, H; Eminler, AT; Toka, B; Basir, H; Saglam, O; Erguel, B; Guel, O; Bueyuektorun, I; Ozel, M; Sair, U; Kosem, G; Nedirli, F; Tahtaci, M; Parlak, E
    Background: Acute pancreatitis (AP) is the most common gastrointestinal disease requiring hospitalization, with significant mortality and morbidity. We aimed to evaluate the clinical characteristics of AP and physicians ' compliance with international guidelines during its management. Methods: All patients with AP who were hospitalized at 17 tertiary centers in Turkey between April and October 2022 were evaluated in a prospective cohort study. Patients with insufficient data, COVID-19 and those aged below 18 years were excluded. The definitions were based on the 2012 revised Atlanta criteria. Results: The study included 2144 patients (median age:58, 52 % female). The most common etiologies were biliary (n = 1438, 67.1 %), idiopathic (n = 259, 12 %), hypertriglyceridemia (n = 128, 6 %) and alcohol (n = 90, 4.2 %). Disease severity was mild in 1567 (73.1 %), moderate in 521 (24.3 %), and severe in 58 (2.6 %) patients. Morphology was necrotizing in 4.7 % of the patients. The overall mortality rate was 1.6 %. PASS and BISAP had the highest accuracy in predicting severe pancreatitis on admission (AUC:0.85 and 0.81, respectively). CT was performed in 61 % of the patients, with the majority (90 %) being within 72 h after admission. Prophylactic NSAIDs were not administered in 44 % of the patients with post-ERCP pancreatitis (n = 86). Antibiotics were administered to 53.7 % of the patients, and 38 % of those received them prophylactically. Conclusions: This prospective study provides an extensive report on clinical characteristics, management and outcomes of AP in real -world practice. Mortality remains high in severe cases and physicians ' adherence to guidelines during management of the disease needs improvement in some aspects. (c) 2023 IAP and EPC. Published by Elsevier B.V. All rights reserved.