Browsing by Author "Kurt F."

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Bladder Function Recovery in Rats With Traumatic Spinal Cord Injury After Transplantation of Neuronal-Glial Restricted Precursors or Bone Marrow Stromal Cells
    (2009) Temeltas G.; Dagci T.; Kurt F.; Evren V.; Tuglu I.
    Purpose: We investigated functional recovery of the lower urinary system in rats with spinal cord injury after transplanting neuronal restricted precursors/glial restricted precursors or neural cells derived from bone marrow stromal cells into the injured area of the spinal cord. Materials and Methods: A total of 30 rats underwent experimentation in 4 groups, including group 1-sham operation, group 2-spinal cord injury plus neuronal restricted precursor/glial restricted precursor transplantation, group 3-spinal cord injury plus bone marrow stromal cell transplantation and group 4-spinal cord injury control. All rats in the 4 groups were investigated urodynamically and sacrificed on day 28 after transplantation. The cells transplanted into the injured spinal cord underwent histological investigation. Results: Transplanted cells (neuronal and glial restricted precursors, and bone marrow stromal cells) were found to maintain a presence in the injured spinal cord area. Baseline pressure, maximum capacity, mean uninhibited contraction amplitude, mean voiding pressure, voided volume and post-void residual volume were significantly better in groups 2 and 3 than in group 4, while baseline pressure in group 2 was better than that in group 3. We found no significant difference among the groups according to mean uninhibited contraction frequency. Conclusions: Although neuronal/glial restricted precursor transplanted rats seemed to have more improvement, all rats in groups 2 and 3 showed some significant improvement in lower urinary system function. On the other hand, the level of this improvement was far from complete functional recovery. © 2009 American Urological Association.
  • No Thumbnail Available
    Item
    The skills of defibrillation practice and certified life-support training in the healthcare providers in Turkey
    (Wiley-Hindawi, 2021) Derinoz-Guleryuz O.; Uysal-Yazici M.; Udurgucu M.; Karacan C.; Akça H.; Ongun E.A.; Ekinci F.; Duman M.; Akça-Çaglar A.; Vatansever G.; Bilen S.; Uysalol M.; Akcan-Yıldız L.; Saz E.U.; Bal A.; Piskin E.; Sahin S.; Kurt F.; Anil M.; Besli E.; Alakaya M.; Gültekingil A.; Yılmaz R.; Temel-Koksoy O.; Kesici S.; Akcay N.; Cebisli E.; Emeksiz S.; Kılınc M.A.; Köker A.; Çoban Y.; Erkek N.; Gurlu R.; Eksi-Alp E.; Apa H.; Kalkan G.; Azapagası E.; Yener N.; Sarac-Sandal O.; Horoz O.O.; Öztürk A.; Tuygun N.; Özdemir İ.; Göktuğ A.; Gökulu G.; Gümüs S.; Teksam O.; Turan C.; Zengin N.; Kardeş H.; Bozan G.; Ünal B.; Bardak S.; Arslanköylü A.E.; Yorulmaz A.; Celegen M.; Sevketoglu E.; Dursun O.; Perk O.; Başpınar O.; Akgul F.
    Aim of the study: Successful cardiopulmonary resuscitation and early defibrillation are critical in survival after in- or out-of-hospital cardiopulmonary arrest. The scope of this multi-centre study is to (a) assess skills of paediatric healthcare providers (HCPs) concerning two domains: (1) recognising rhythm abnormalities and (2) the use of defibrillator devices, and (b) to evaluate the impact of certified basic-life-support (BLS) and advanced-life-support (ALS) training to offer solutions for quality of improvement in several paediatric emergency cares and intensive care settings of Turkey. Methods: This cross-sectional and multi-centre survey study included several paediatric emergency care and intensive care settings from different regions of Turkey. Results: A total of 716 HCPs participated in the study (physicians: 69.4%, healthcare staff: 30.6%). The median age was 29 (27-33) years. Certified BLS-ALS training was received in 61% (n = 303/497) of the physicians and 45.2% (n = 99/219) of the non-physician healthcare staff (P <.001). The length of professional experience had favourable outcome towards an increased self-confidence in the physicians (P <.01, P <.001). Both physicians and non-physician healthcare staff improved their theoretical knowledge in the practice of synchronised cardioversion defibrillation (P <.001, P <.001). Non-certified healthcare providers were less likely to manage the initial doses of synchronised cardioversion and defibrillation: the correct responses remained at 32.5% and 9.2% for synchronised cardioversion and 44.8% and 16.7% for defibrillation in the physicians and healthcare staff, respectively. The indications for defibrillation were correctly answered in the physicians who had acquired a certificate of BLS-ALS training (P =.047, P =.003). Conclusions: The professional experience is significant in the correct use of a defibrillator and related procedures. Given the importance of early defibrillation in survival, the importance and proper use of defibrillators should be emphasised in Certified BLS-ALS programmes. Certified BLS-ALS programmes increase the level of knowledge and self-confidence towards synchronised cardioversion-defibrillation procedures. © 2021 John Wiley & Sons Ltd
  • No Thumbnail Available
    Item
    COVID-19 disease in children presenting to the pediatric emergency department: A multicenter study with 8886 cases from Turkey
    (W.B. Saunders, 2022) Duman M.; Şık N.; Tekşam Ö.; Akça H.; Kurt F.; Çağlar A.A.; Yıldız L.A.; Taşar M.A.; Fidancı İ.; Yayla B.C.C.; Yılmaz D.; Güngör E.; Demir Ş.; Çokuğraş H.; Cebeci S.O.; Önal P.; Saz E.U.; Yurtseven A.; Uysalol M.; Yıldız R.; Gümüş S.; Bal A.; Bayturan S.Ş.; Zengin N.; Atik S.; Çiftdoğan D.Y.; Berksoy E.; Çiçek A.; Şahin S.; Kızıl M.C.; Kara Y.; Apa H.; Ulusoy E.; Kara A.A.; Yesil E.; Erdem M.; Turan C.; Arslanoglu S.; Duyu M.; Besli G.E.; Arslan G.; Oflu A.T.; Çeleğen M.; Buldu E.; Pişkin İ.E.; Kardeş H.; Yılmaz H.L.; Yıldızdaş D.; Gökulu G.; Çay P.; Özer U.; Güleryüz O.D.; Çolak Ö.; Güneysu S.T.
    Background: The aim was to evaluate the epidemiological, clinical, laboratory, and radiologic data of children with SARS-CoV-2 positivity by polymerase chain reaction (PCR) together with treatment strategies and clinical outcomes and to evaluate cases of multisystem inflammatory syndrome in children (MIS-C) in this population. Methods: This was a multicenter retrospective observational cohort study performed in the pediatric emergency departments of 19 tertiary hospitals. From March 11, 2020, to May 31, 2021, children who were diagnosed with confirmed nasopharyngeal/tracheal specimen SARS-CoV-2 PCR positivity or positivity for serum-specific antibodies against SARS-CoV-2 were included. Demographics, presence of chronic illness, symptoms, history of contact with SARS-CoV-2 PCR-positive individuals, laboratory and radiologic investigations, clinical severity, hospital admissions, and prognosis were recorded. Results: A total of 8886 cases were included. While 8799 (99.0%) cases resulted in a diagnosis of SARS-CoV-2 with PCR positivity, 87 (1.0%) patients were diagnosed with MIS-C. Among SARS-CoV-2 PCR-positive patients, 51.0% were male and 8.5% had chronic illnesses. The median age was 11.6 years (IQR: 5.0–15.4) and 737 (8.4%) patients were aged <1 year. Of the patients, 15.5% were asymptomatic. The most common symptoms were fever (48.5%) and cough (30.7%) for all age groups. There was a decrease in the rate of fever as age increased (p < 0.001); the most common age group for this symptom was <1 year with the rate of 69.6%. There was known contact with a SARS-CoV-2 PCR-positive individual in 67.3% of the cases, with household contacts in 71.3% of those cases. In terms of clinical severity, 83 (0.9%) patients were in the severe-critical group. There was hospital admission in 1269 (14.4%) cases, with 106 (1.2%) of those patients being admitted to the pediatric intensive care unit (PICU). Among patients with MIS-C, 60.9% were male and the median age was 6.4 years (IQR: 3.9–10.4). Twelve (13.7%) patients presented with shock. There was hospital admission in 89.7% of these cases, with 29.9% of the patients with MIS-C being admitted to the PICU. Conclusion: Most SARS-CoV-2 PCR-positive patients presented with a mild clinical course. Although rare, MIS-C emerges as a serious consequence with frequent PICU admission. Further understanding of the characteristics of COVID-19 disease could provide insights and guide the development of therapeutic strategies for target groups. © 2022 Elsevier Inc.