Browsing by Author "Müezzinoglu T."

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Endobronchial metastasis from urinary bladder cancer.; [Mesane kanserinin endobronşiyal metastazi]
    (2005) Sakar A.; Gencer N.; Demireli P.; Müezzinoglu T.; Celik P.; Yorgancioglu A.
    A rare case, a case of endobronchial metastasis from urinary bladder carcinoma is reported. A 70 years-old man was admitted with hematuria. He has a mass in urinary bladder and a mass in lung. He has no pulmonologic symptom. He is a smoker with 75 pack-years. Thorax computerized tomography revealed a mass in left lung upper lobe. Bronchoscopy demonstrated an endobronchial tumor in left upper lobe, apikoposterior segment. Histopathologically diagnosis was endobronchial metastasis from urinary bladder carcinoma. He received five courses of chemotherapy (cisplatin + gemcitabine). The mass was regressed after three months. Our patient lived for one year from diagnosis.
  • No Thumbnail Available
    Item
    Evaluation of risk factors and severity of a life threatening surgical emergency: Founder's gangrene (a report of 15 cases)
    (ARSMB-KVBMG, 2009) Kara E.; Müezzinoglu T.; Temeltas G.; Dinçer L.; Kaya Y.; Sakarya A.; Coskun T.
    Background: Fournier's gangrene is a rare, rapidly progressive, necrotising fasciitis of the external genitalia and perineum with high morbidity and mortality. Patients and Methods: 15 patients with Fournier's gangrene were enrolled. Gender, age, aetiology, predisposing factors, symptomatology, associated diseases, hospital stay, FGSI, and body surface area were analysed. Results: Ten males and five females were enrolled in the study. The mean age was 54 years (range 23-81). E.coli and acinetobacter were the common organisms cultured. All patients were treated with a common approach of resuscitation, broad-spectrum antibiotics, and wide surgical excision. Common predisposing factors included diabetes mellitus (73.3%), poor personal hygiene (60%), obesity (33.3%), psychosis (20%) and decubitus ulcers (13.2%). Whereas five (33.3%) patients developed synergistic gangrene of the scrotum secondary to anorectal disease, five (33.3%) had a urological source of infection. Mean BSA and FSGI scores were 15.93 ±3.13 and 6.02 ±0.95, respectively. Serum glucose > 140 mg/dl, the existence of septic shock on admission, the spread of gangrene to the perineum and abdominal wall (Groups C and D), BSA ≥: 24 cm2, a cutaneous source of infection and FGSI scores ≥ 7 were factors affecting mortality rates with statistical significance (p < 0.05). There was a direct correlation between the culture of mixed type micro-organisms and the cutaneous source of infection (p > 0.05). The extent of gangrene correlated with higher FGSI scores (≥ 7) (p < 0.05). Mortality and morbidity rates were as 20% (n = 3) and 60% (n = 9). Conclusion: Aggressive surgical debridement and combined antibiotherapy are essential in the management of Fournier's gangrene. FGSI and BSA are useful to assess the severity and prognosis of the disease.
  • No Thumbnail Available
    Item
    Assessment of PSA-Age volume score in predicting positive prostate biopsy findings in Turkey
    (Brazilian Society of Urology, 2015) Uçer O.; Yücetas U.; Çelen I.; Toktas G.; Müezzinoglu T.
    Objectives: To evaluate PSA-age volume (AV) scores in predicting positive prostate biopsy findings in Turkey. Materials and Methods: PSA-AV was calculated by multiplying the patient's age by the prostate volume and dividing it by the PSA level. Sensitivities and specificities of the PSA-AV were assessed by retrospective analysis of findings from 4,717 prostate biopsies. Results: The population's average age was 63.71±7.63 years, the mean PSA level was 9.73±17.01ng/mL, the mean prostate volume was 44.46±23.88 cm3. Of the 4,717 prostate biopsies, 1,171 biopsy specimens (24.8%) were positive for prostate cancer. A PSA- -AV score of 700 had a sensitivity and specificity of 95% and 15%, respectively. These values were similar to the sensitivity and specificity for a PSA cut-offof 4ng/mL (94% and 13%, respectively). Although the sensitivity of a PSA-AV cut-offof 700 in patients over 60 years was similar to the PSA cut-offof 4ng/mL and the age-adjusted PSA, in patients <60 years, its sensitivity was higher. While the sensitivities of a PSA-AV cut- -offof 700 in patients with low prostate volume was higher than a PSA cut-offof 4ng/mL, the sensitivities of both methods with moderate prostate volumes were similar. Conclusions: Considering all the biopsies, the sensitivity and specificity of a PSA-AV of 700 for predicting positive biopsy findings were similar to a PSA of 4ng/mL. We suggest the PSA-AV cut-offof 700 should only be used in patients younger than 60 with low prostate volumes (<20cm3).