Browsing by Author "Mütevelizade G."

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    Contribution of Open Mouth Technique in18F-FDG PET/CT Imaging in Patients with Malignant Lip Neoplasm; [Dudak Malign Neoplazmı Tanılı Hastaların18F-FDG PET/BT Görüntülemesinde Ağız Açık Pozisyonlamanın Katkısı]
    (Galenos Publishing House, 2022) Mütevelizade G.; Sezgin C.; Parlak Y.; Gümüşer G.; Sayit E.
    Objectives:18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) plays an important role in evaluating head and neck cancers. However, localization and size evaluation in this region can be rough due to the multitude of the anatomic structures and physiologic uptakes. The aim of this study was to evaluate malignant lip lesions with the contribution of open mouth (OM) imaging technique at PET/CT. Methods: Fifty-six patients with malignant lip neoplasm underwent18F-FDG PET/CT imaging. Each patient was imaged twice as whole-body PET/ CT with routine closed mouth (CM) position; and OM head and neck image, standardized with a special device. Lesion maximum standard uptake value (SUVmax), localization, size, and involvement of lymph nodes were evaluated. Results: Lesion localization was correctly detected in 100% of the OM images. Lesion size in PET/CT was compared with clinical, radiological (magnetic resonance imaging and CT) and/or histopathological results and the size measurement was coherent at 47.1% and 95.6% for CM and OM images, respectively. It was observed that OM acquisition did not contribute additionally in detecting regional lymph node metastasis. Forty-one PET/CT scans with CT artifacts due to dental amalgams were evaluated and 46.3% dimensional and 53.7% localization errors were detected in the CM position. There was no statistically significant difference between OM and CM SUVmax (p>0.05). Conclusion: We concluded that additional OM head and neck imaging is useful and necessary to accurately determine the localization and size of the tumor, thus enhancing the value of PET/CT in staging, treatment response assessment, and restaging of patients with malignant lip cancer with or without dental amalgam. © 2022 by Turkish Society of Nuclear Medicine Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi.
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    Unexpected Metastatic Localizations of Prostate Cancer Determined by68Ga PSMA PET/CT: Series of Four Cases; [68 Ga PSMA PET/BT’de Saptanan Prostat Kanserinin Nadir Metastaz Lokalizasyonları: Dört Olgu]
    (Galenos Publishing House, 2022) Mütevelizade G.; Sezgin C.; Gümüşer G.; Sayit E.
    Prostate-specific membrane antigen (PSMA) is a transmembrane protein with overexpression in most prostate cancer cells. Gallium-68-(68Ga) PSMA positron emission tomography/computed tomography (PET/CT) imaging is a game-changer in the management of prostate cancer.68Ga PSMA PET/CT scan is advanced and a promising radioligand has high sensitivity in determining lesions of prostate cancer with a high tumor to background ratio. The most common areas of metastasis are the bone and pelvic lymph nodes. The prognosis of prostate cancer is mainly determined by the status of metastases. The presence and the localization of metastases affects treatment planning. In our cases, we presented some examples of uncommon sites of metastases such as the brain, adrenal glands, penis and orbit. Improvements in imaging techniques, such as68Ga PSMA PET/CT have led to the possibility to make more determination of rare metastase sites in prostate cancer patients. © 2022 by Turkish Society of Nuclear Medicine Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi.