Browsing by Author "Mayali, H"

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    Quantitative analysis of early retinal vascular changes in type 2 diabetic patients without clinical retinopathy by optical coherence tomography angiography
    Altinisik, M; Kahraman, NS; Kurt, E; Mayali, H; Kayikcioglu, O
    Purpose To investigate the quantitative differences in optical coherence tomography angiography (OCTA) data between type 2 diabetes patients without clinically detectable diabetic retinopathy (DR) and healthy subjects. Methods Thirty-nine patients with type 2 diabetes without DR and 41 age- and sex-matched healthy controls were recruited. The vessel density and foveal avascular zone (FAZ) area in the superficial capillary plexus and deep capillary plexus were measured using Nidek RS-3000 Advance (R) and compared between patient cohorts. Foveal vessel density (%) and FAZ (%) were also calculated. Results A significant decrease in vessel density has been observed in the deep capillary plexus of the patients compared to healthy individuals (5.58 +/- 0.98 mm(2) versus 6.15 +/- 0.89 mm(2), p < 0.001). However, there were no significant differences in other parameters between cohorts (p > 0.05 in all parameters). Despite the decrease of deep capillary plexus density in the macular region, there was no significant change observed in foveal vessel density (p:0.44). It has also been observed that the duration of diabetes mellitus correlates with vessel density decrease in deep capillary plexus (R:-0.52; p < 0.001). In both groups, all parameters in deep capillary plexus were significantly higher than superficial capillary plexus (p < 0.001 for all parameters). Conclusions OCTA can identify quantitative changes in DCP before the manifestation of clinically apparent retinopathy. DCP-VD reduction may be an earlier finding than FAZ enlargement. Despite the reduction of VD, FVD could be preserved for a certain period of time in DM patients.
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    A multimodal ophthalmic analysis in patients with systemic sclerosis using ocular response analyzer, corneal topography and specular microscopy
    Mayali, H; Altinisik, M; Sencan, S; Pirildar, T; Kurt, E
    PurposeTo conduct a multimodal ophthalmic evaluation of systemic sclerosis (SSc) in patients using ocular response analyzer (ORA), Pentacam, and specular microscopy (SM).MethodsThirty-one SSc patients and a group of age- and sex-matched controls were enrolled in this cross-sectional study. Corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc), and Goldmann-correlated IOP (IOPg) were measured with ORA. Anterior chamber depth (ACD), central corneal thickness (CCT), and corneal volume (CV) measurements were obtained using Pentacam. Corneal endothelial cell density (ECD) and CCT were evaluated by SM.ResultsSSc patients had significantly lower CH, ACD, and ECD values compared to the control group (p=0.018;<0.001;<0.001, respectively). There was no significant difference regarding CRF, IOP, CV, or CCT measurements acquired by Pentacam and SM. Regarding CCT, SM and Pentacam showed relatively better agreement in SSc patients.ConclusionsMultimodal imaging can provide more comprehensive and useful information regarding the ocular involvement of systemic diseases. The multimodal evaluation in our study demonstrated that the pathologic effects of SSc may manifest as reductions in ACD, corneal elasticity, and ECD before there are any detectable changes in corneal thickness or IOP.
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    Pulsatile Proptosis and Sphenoid Wing Dysplasia with no Evidence of Neurofibromatosis Type 1: A Case Report and Review of the Literature
    Akgün, YD; Erdogan, M; Altinisik, M; Mayali, H; Ilker, SS
    In this study, we aimed to present a rare case of pulsatile proptosis due to sphenoid wing dysplasia without the features of neurofibromatosis type 1 (NF1). A 17-year-old male patient presented with swelling in the superotemporal region of the right eye. Physical examination revealed facial asymmetry with a pulsatile, ill-defined, soft lesion with in the superotemporal region of the right orbit associated with pulsatile proptosis, downward dystopia, and hypotropia. Computer tomography imaging to establish a differential diagnosis showed temporal lobe herniation secondary to sphenoid wing dysplasia. The patient was assessed for NF1, which is most commonly associated with sphenoid wing dysplasia, but no evidence supporting the diagnosis was found. Patients presenting with proptosis should be carefully examined for pulsation and murmurs, and a trauma history should be investigated. Radiological imaging should be used to facilitate the differential diagnosis, and the current clinical condition should be managed with a multidisciplinary approach.
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    Should we worry about the eyes of celiac patients?
    Dogan, G; Sen, S; Çavdar, E; Mayali, H; Özyurt, BC; Kurt, E; Kasirga, E
    Purpose: In this article, we evaluate subfoveal choroidal thickness in celiac patients with respect to adherence to the gluten-free diet and nonadherence to the gluten-free diet, comparing with age and sex matched healthy controls using spectral-domain optical coherence tomography. Materials and Methods: A case-control study among 42 celiac patients and 42 healthy participants was conducted in the Department of Pediatric Gastroenterology. Celiac patients of our policlinics compliant with spectral-domain optical coherence tomography examination enrolled in the study. Celiac patients had been asked verbally about their adherence to gluten-free diet, were evaluated according to negative or positive EmA and anti-TG2 for defining adherence, and were divided into two groups (adherence to gluten-free diet and nonadherence to gluten-free diet). Results: Subfoveal choroidal thickness was thinner in EmA (+) or anti-TG2 (+) eyes than EmA(-) or anti-TG2 (-) eyes in celiac patients, but it was not statistically significant. The mean subfoveal choroidal thickness values in eyes with celiac disease, whose diagnosis time was longer than 60 months, were thinner than shorter group. Longer duration of gluten-free diet was associated with adherence difficulty and thinner choroidal thickness (r = -0.15, p = 0.34). Adherence to gluten-free diet was 88.2% for children below the age of 60 months and 57.1% for children older than 60 months. Conclusion: In conclusion, in addition to other extraintestinal manifestations of celiac disease, diagnosis time longer than 60 months in pediatric celiac patients, nonadherence to the gluten-free diet, and antibody positivity should be focused on during ophthalmologic examination and choroid measurement.
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    Evaluation of the Relationship Between Systemic Hypertension and Subfoveal Choroidal Thickness Using Optical Coherence Tomography in Pediatric Patients
    Alkan, F; Sen, S; Çavdar, E; Mayali, H; Coskun, S
    Objective: Hypertension (HT) can cause vascular and microvascular changes. There is no barrier between systemic blood and ocular region. Changes in choroidal perfusion pressure due to HT may impair retinal function and oxygenation, and subfoveal choroidal thickness (SCT) may be affected by these changes. The aim of this study was to evaluate the effect of arterial HT on SCT in children. Method: The study was performed on 102 cases (51 patients and 51 controls), prospectively. Optical coherence tomography was used for the measurement of SCT and mean values of 3 consecutive measurements were evaluated. All cases had blood pressure measurements during all day via ambulatory blood pressure monitoring. Also, both groups were evaluated for the target organ damage. Results: There were 51 cases in patient group with the average age of 14.4 +/- 2.8 years, and the rest of 51 control cases were meanly 14.5 +/- 2.8 years in age (p=0.980). SCT was measured thinner in patients with target organ damage than the cases without target organ damage (p=0.027). SCT measurements of patients and control cases were not statistically significant different (p=0.569). Especially SCT was statistically significantly thinner in cases with increased left ventricular mass, left ventricular mass index and hypertensive nephropathy (p=0.02, p=0.00, p=0.039, respectively). Conclusion: Choroidal thickness decreases in patients with HT who develop target organ damage. Therefore, close follow-up of hypertensive patients with appropriate life changes and medical treatments is important before target organ damage develops.
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    Unintentional Staining of the Anterior Vitreous With Trypan Blue During Cataract Surgery
    Kayikçioglu, ÖR; Mayali, H; Dogruya, S; Alp, S; Yilmazlar, AA; Kurt, E
    During phacoemulsification and intraocular lens (IOL) implantation surgery, the trypan blue dye used to stain the anterior capsule passed into vitreous cavity and stained the anterior capsule and anterior vitreous in 6 patients. There was history of trauma in 2 patients, uveitis in 1 patient, mature cataract in 1 patient, and no risk factors in the other patients. IOL was implanted in-the-bag without problem in 5 patients. In the patient with iris and zonular defects due to trauma, a sutured IOL was implanted in the same session. The migration of trypan blue into the vitreous cavity through damaged or intact lens zonules is a rare but important complication that makes subsequent surgical steps substantially more difficult.
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    Multimodal ocular evaluation in hemodialysis patients
    Mayali, H; Altinisik, M; Sarigul, C; Toraman, A; Turkoglu, MS; Kurt, E
    Purpose To evaluate choroidal thickness, intraocular pressure (IOP), axial length, central corneal thickness (CCT), lens thickness, anterior chamber depth, and ocular pulse amplitude (OPA) in hemodialysis patients. Materials and methods The patients with end-stage renal disease and undergoing hemodialysis were included in the study. Immediately before and 1 hour after hemodialysis, all patients underwent measurement of choroidal thickness with spectral domain optical coherence tomography (SD-OC, Cirrus HD-OCT; Carl Zeiss Meditec Inc., Dublin, CA), IOP and OPA with Pascal dynamic contour tonometry (Ziemer Ophthalmic Systems AG, Port, Switzerland), and anterior chamber depth, lens thickness, and axial length with optical biometry (LenStar LS900; Haag-Streit AG, Koeniz, Switzerland). Data from the patients' right eyes were included in the statistical analysis. Results The patient group included 8 (36.4%) males and 14 (63.6%) females with a mean age of 56, 14 +/- 9, 96 (40-70) years. The mean subfoveal choroidal thickness before and after hemodialysis was 255.21 +/- 6.15 (245-263) mu m and 234.95 +/- 7.89 (220-247) mu m, respectively (p < 0.001). Mean choroidal thickness at 1500 mu m and 3000 mu m nasal and temporal of the fovea also decreased significantly after hemodialysis (p < 0.001). Mean OPA values before and after hemodialysis were 2.14 +/- 1.07 (0.6-4) mmHg and 1.6 +/- 0.86 (0.5-3.2) mmHg, respectively (p < 0.001). There was a statistically significant correlation between OPA and choroidal thickness measurements (p < 0.001, R = 0.923). IOP increased from 15.11 +/- 2.58 (11-20) to 15.99 +/- 2.21 (13-20) mmHg, but the change did not reach statistical significance (p = 0.05). There was no statistically significant change in mean axial length, anterior chamber depth, lens thickness, or CCT after hemodialysis (p > 0.05 for all). Conclusion Although choroidal thickness and OPA may be decreased immediately after hemodialysis, there may be no significant changes in IOP or avascular ocular structures such as the lens and cornea.
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    Shaken baby syndrome in an infant treated for retinopathy of prematurity with anti-VEGF injection
    Devebacak, A; Bekmez, S; Eris, E; Mayali, H; Yurtseven, I; Celik, Y; Bag, O
    We present the case of an infant who received bevacizumab treatment for retinopathy of prematurity (ROP) and developed retinal hemorrhages 12 weeks later. Although preretinal hemorrhages along the ROP's ridge were a concern for recurrence, we decided to investigate other etiologies because of numerous retinal hemorrhages in different retinal layers and their concentration in the posterior pole. Cranial magnetic resonance imaging revealed a new-onset subdural hemorrhage. Factors that were suspicious for trauma were identified in the detailed history taken from the family by the hospital's child abuse team. This case highlights the importance of considering the characteristics of retinal hemorrhages in infants with ROP and conducting any necessary investigation.
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    Comparison of Icare Pro Tonometry and Icare one Tonometry Measurements in Healthy Eyes
    Mayali, H; Sarigül, Ç; Kurt, E; Kayikçioglu, ÖR; Ilker, SS
    Objectives: To compare intraocular pressure (IOP) measurements obtained with the Icare Pro tonometer used in clinical practice and the Icare One self-tonometer. Materials and Methods: Fifty-two eyes of 52 healthy, right-handed individuals with no prior intraocular surgery or ocular trauma, structural ocular pathology, or systemic disease were evaluated. IOP was first measured using the Icare Pro tonometer. The participants were then told how to use the Icare One tonometer and asked to measure their own IOP The results were analyzed statistically using SPSS v.24. Results: Of the 52 healthy participants, 16 (30.7%) were male and 36 (69.3%) were female. Their mean age was 31.6 +/- 6.3 (23-47) years. Mean IOP measured with the Icare Pro was 17.10 +/- 6.2 (11.5-25.2) mmHg, and the mean self-measured IOP with Icare One was 14.01 +/- 3.4 (7-24) mmHg. When the two methods were compared using Levene's t-test, there was a significant mean difference of -3.08 +/- 0.6 (95% confidence interval: -4.39 -1.78; p<0.001). Conclusion: In this study, there was a significant difference between the IOP measurements we made using the Icare Pro and the participants' self-measured IOP using the Icare One, with the latter being relatively lower. This may be related to the fact that the participants were unfamiliar with using the Icare One. Although the Icare One is a promising tool for glaucoma patients to self-monitor their IOP, further studies are needed.
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    Clinical Results in Patients with Combined Penetrating Keratoplasty and Vitreoretinal Surgery Using Landers Wide-field Temporary Keratoprosthesis
    Mayali, H; Kayikçioglu, Ö; Altinisik, M; Biçak, F; Kurt, E
    Objectives: To evaluate the clinical results of corn bined pars plana vitrectomy (PPV) with Landers wide-field temporary keraroprosthesis and penetrating keratoplasty (PK). Materials and Methods: From January 2016, traumatic eyes with coexisting corneal and vitreoretinal diseases that underwent combined keratoprosthesis/PPV/PK surgery were retrospectively evaluated. Demographic characteristics, visual acuity (VA), intraocular pressure (IOP) and clinical findings of the cornea, lens, and retina were recorded during the follow-up. Cases with clear corneal graft, attached retina, normotonic IOP, and improved or stable VA were considered successful. Results: Eight eyes were enrolled in the study. The mean follow-up time was 21.1 +/- 8.20 months. Surgery was performed a mean of 23 (10-40) days after trauma. Preoperative VA ranged from no light perception to counting fingers from 50 cm. Postoperatively, corneal graft was clear in 5 patients (62.5%) and retina was attached in 6 eyes (75%). Chronic hypotonia developed in 3 patients (37.5%). VA was unchanged in 3 patients and improved in 5 patients. A total of 5 cases (50%) were considered successful. Shorter interval between trauma and surgery was associated with higher likelihood of success (p=0.043). No significant difference was observed between the groups in terms of type or location of trauma (p= 1; p= 0.143). Conclusion: Although the functional results are not very satisfactory, the combined procedure provides a final opportunity for preserving remaining vision and anatomic reconstruction in eyes that will otherwise result in phthisis due to severe anterior and posterior segment pathologies.
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    Corneal endothelial damage in phacoemulsification using an anterior chamber maintainer compared with using an ophthalmic viscosurgical device
    Mayali, H; Baser, EF; Kurt, E; Ilker, SS
    Purpose: To compare the effects of phacoemulsification surgery (PE) using an anterior chamber maintainer (ACM) and conventional PE using an ophthalmic viscosurgical device (OVD) on corneal endothelial cells. Setting: Department of Ophthalmology, Celal Bayar University, Manisa, Turkey. Design: Prospective randomized controlled trial. Methods: Eyes in the OVD group (n = 50) underwent conventional PE, whereas eyes in the ACM group (n = 50) underwent PE using an ACM. Endothelial cell density (ECD), coefficient of variation (CV), hexagonality (HEX), and noncontact central corneal thickness (CCT) measurements were performed by specular microscopy before and at 1 month, 3 months, and 6 months after PE. Results: This study included 100 eyes of 97 patients undergoing PE. The mean age was 64.7 ? 10.6 years in the OVD group, 64.0 ? 12.6 years in the ACM group (P > .05). The groups did not differ significantly in preoperative ECD, CV, HEX, and CCT or total PE time (P > .05 for all). ECD was significantly lower in the ACM group compared with the OVD group at postoperative 1 month, 3 months, and 6 months (P = .002, P = .002, and P = .001, respectively). Similarly, ECD loss compared with preoperative value was greater in the ACM group at all postoperative timepoints (P = .003, P = .001, and P = .001, respectively). CV increased and HEX decreased in both groups postoperatively (P > .05 for both). CCT showed a transient increase of less than 10 mm at postoperative 1 month in both groups (P = .296). Conclusions: PE with ACM was associated with greater corneal ECD loss compared with conventional PE. ACM should not be used during PE in patients with limited corneal endothelial reserve. J Cataract Refract Surg 2021; 47:612?617 Copyright ? 2021 Published by Wolters Kluwer on behalf of ASCRS and ESCRS
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    Evaluation of the Effect of Body Position on Intraocular Pressure Measured with Rebound Tonometer
    Mayali, H; Tekin, B; Kayikçioglu, ÖR; Kurt, E; Ilker, SS
    Objectives: It is important to determine variables that influence intraocular pressure (IOP) measurement. This study aimed to evaluate the effect of body position on IOP. Materials and Methods: The study included 52 right eyes of 52 patients who presented to the ophthalmology department of our hospital and had no ocular disease except refractive errors. IOP was measured with an Icare PRO tonometer while patients were in sitting, standing, and supine positions, with intervals of 10 minutes between the positions. Correlations between the results were evaluated using Spearman's correlation analysis and Wilcoxon tests. Results: Thirty-six of the 52 patients were female, 16 were male. Mean age was 31.65 +/- 6.30 (23-47) years. Mean IOP values in the sitting, standing, and lying positions were 17.76 +/- 3.41 (12.70-25.60) mmHg, 17.10 +/- 3.27 (11.50-25.20) mmHg, and 18.46 +/- 4.67 (10.50-29.40) mmHg, respectively. There were no statistically significant differences between measurements taken in the different positions (p=0.112, p=0.472, p=0.071). We observed that there was no relationship between age and body position (p>0.45, p>0.79, p>0.77) or between gender and position (p>0.59, p>0.69, p>0.54). Conclusion: Gender and age had no effect on IOP measured in different body positions. There were also no significant differences between IOP values measured in the different positions. Therefore, we believe the portable Icare PRO tonometer can be used for patients who are confined to bed and will provide IOP measurements that are concordant with values obtained while sitting.
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    A Retinal Detachment Case with a Delay in Diagnosis Due to Unilateral Lens Coloboma and Bilateral Ectopic Pupil
    Mayali, H; Ilker, SS; Kiliç, S; Kurt, E; Ulusoy, O
    A 29-year-old female patient was admitted with the complaint of decreased vision in the left eye for the last 9 months. The visual acuity was 0.4 in the right eye and hand movements in the left eye. Biomicroscopic examination revealed ectopic pupils in both eyes and lens coloboma in the left eye; her right lens was normal. There was total retinal detachment in the left fundus. Optic disc, macula, and peripheral retina were normal in the right eye at her fundus examination. In our case, reduction of vision in the left eye was associated with ectopic pupil at various centers and this situation has led to delay in the diagnosis. Therefore, the importance of careful retinal examination should be kept in mind in cases in which the reduction of vision does not correlate with clinical picture.
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    RETRACTED: Evaluation of macular thickness and visual pathways using optic coherence tomography and pattern visual evoked potential in different clinical stages of obstructive sleep apnea syndrome (Retracted Article)
    Ak, AK; Batum, M; Göktalay, T; Mayali, H; Kurt, E; Selçuki, D; Yilmaz, H
    Aim The present study aimed to investigate and compare possible changes in amplitude and latency of pattern visual evoked potentials (PVEP) and thickness of quadrants of the macula (TQM) using optic coherence tomography (OCT). Materials and Methods According to polysomnography examinations, 30 mild, 30 severe, 30 controls were included in the study after approval from the ethics committee. Results No significant difference was found in age and gender between the groups (p = 0.184 andp = 0.954). Significant difference was found between external and internal superior TQM, mean thickness of ganglion cell layer in comparison of all three groups (p = 0.011,p = 0.047,p = 0.030). In comparison between severe OSAS and control groups, significant difference was found in internal nasal, internal superior and external superior TQM (p = 0.048,p = 0.033,p = 0.014) while no significant difference was found TQM in comparison between the mild OSAS and control groups. In comparison between the group of severe OSAS and controls, significant increase was found in P100 as well as N145 latencies whereas only P100 latency was found to increase when mild OSAS was compared with controls. No significant correlation was found between TQM and PVEP parameters in mild and severe OSAS patients. Discussion Latency and amplitude of PVEP altered in OSAS because edema and inflammation was remarkable in mild as well as severe stages of the disease. Furthermore, thinning in the macula was observed only in severe stages of the disease, explained with level of atrophy and exposure to extended hypoxia.
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    Evaluation of retinal fiber thickness and visual pathways with optic coherence tomography and pattern visual evoked potential in different clinical stages of obstructive sleep apnea syndrome
    Ak, AK; Batum, M; Göktalay, T; Mayali, H; Kurt, E; Selçuki, D; Yilmaz, H
    Purpose To investigate the possible changes in retinal nerve fiber layer (RNFL) by optic coherence tomography and in the amplitudes and peak times (PTs) in pattern visual evoked potential (pVEP) and to compare them in obstructive sleep apnea syndrome (OSAS). Methods This prospective study included patients with mild OSAS (n = 30), severe OSAS (n = 30), and 30 control subjects. All patients were assessed after obtaining the approval from our hospital's ethics committee. Results There was no difference in age and gender between the groups (p = 0.184, p = 0.954). By analysis of variance, there was a significant difference in RNFL values among patients with mild OSAS, severe OSAS, and control for three measures of RNFL (average p = 0.044, nasal p = 0.003, inferior p = 0.027). In severe OSAS group, nasal and inferior quadrants of the RNFL were found to be thinner than the control group (p = 0.008, p = 0.031). We showed that the PT of P100 and N145 was prolonged in severe OSAS compared to the control group (p < 0.001) and that PT of P100 was prolonged in mild OSAS compared to the control group (p < 0.05). The amplitude of N75-P100 was significantly decreased in patients with both severe OSAS and mild OSAS compared to the control group (p < 0.001). Correlation of RNFL and pVEP values showed that the inferior quadrant RNFL thickness is correlated with both P100 and N145 PTs (r = 0.271*, p = 0.036 and r = 0.290*, p = 0.043, respectively) and N75-P100 amplitude (r = 0.378**, p = 0.003) in severe OSAS group. Conclusions In mild and severe stages of the disease, edema and inflammation were evident and VEP PT and amplitudes were affected in both groups. Furthermore, thinning in RNFL in the severe stage of the disease might be associated with higher atrophy levels and prolonged exposure to hypoxia.
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    Histopathological Results of Conjunctival Masses with Suspected Malignancy Based on Slit-lamp Biomicroscopy
    Erdogan, M; Mayali, H; Malgaz, S; Altinisik, M; Ilker, SS
    Objective: To evaluate the histopathological results of conjunctival masses suspected to be malignant based on biomicroscopic exami-nation.Study Design: Observational study.Place and Duration of the Study: Department of Ophthalmology, Celal Bayar University, Hafsa Sultan Hospital, Manisa, Turkiye, from November 2013 to February 2021.Methodology: Patients who underwent excision for the diagnosis and treatment of conjunctival surface masses with clinical suspicion of malignancy were evaluated retrospectively. The masses were categorised as benign, premalignant, and malignant lesions according to the histopathological results. The distribution of conjunctival masses was analysed according to patients' gender and age groups.Results: The study included 98 conjunctival masses in 98 patients (57.1% men, mean age 48.6 & PLUSMN;21.85 years). On pathological examina-tion, 63 of the masses were found to be benign (64.3%), 22 were premalignant (22.4%), and 13 were malignant (13.3%). The most common benign lesion was nevus (n=21, 21.4%). All detected premalignant lesions were conjunctival intraepithelial neoplasms (CIN), detected in 22 patients (22.4%). Of these, 13 patients (13.3%) had carcinoma in situ (CIN III). Thirteen (13.3%) of the masses were malignant, the most common being squamous cell carcinoma (n=10, 10.2%). The frequency of premalignant and malignant lesions increased with age (p<0.001). There was no statistical relationship between malignancy and gender (p=0.619). Conclusion: Most conjunctival masses in this series were benign, with nevi being the most common. The most common premalignant and malignant lesions were intraepithelial neoplasia and squamous cell carcinoma, respectively. Malignant conjunctival lesions were more common in older patients.
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    Cross-validation of the Turkish version of the 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ 25)
    Toprak, AB; Eser, E; Guler, C; Baser, FE; Mayali, H
    Purpose: To test the validity and reliability of the Turkish version of the self-administered form of the National Eye Institute Visual Functioning Questionnaire (NET-VFQ25). Methods: Patients with no limitations to respond to a health status interview and affected by a chronic eye disease were enrolled. The Turkish versions of the abbreviated form of World Health Organization Quality of Life (WHOQOL-BREF) and the NEI-VFQ25 instruments were administered to all participants. Results: The mean (SD) age of the participants was 60.9 (14.5) years. There were 61 patients with one of the following conditions: Cataract (57.4%), diabetic retinopathy (13.2%), age related macular degeneration (ARMD) (11.4% glaucoma (9.8%) and degenerative myopia (8.2%). The Cronbach alpha of the overall scale was 0.97; the Cronbach alpha ranged from 0.94 to 0.78 for the subscales. The physical, psychological, environmental and social domains of the WHOQOL-BREF had fair to good correlations with the NEI-VFQ25 (r = 0.68 to r = 0.26), which indicated a sufficient convergent validity. Patients with lower visual acuity (VA) had lower index scores than those with higher VA (p = 0.001), which showed a sufficient responsiveness. Conclusion: Statistical analysis showed that Turkish version of the NEI-VFQ is a valid and reliable instrument to measure vision-related quality of life in patients with chronic eye diseases.
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    Neuroblastoma in a Case with Congenital Horner's Syndrome
    Mayali, H; Ilker, SS; Kiliç, S; Sürücü, B; Özgüven, A
    Miosis, ptosis, and ipsilateral facial anhidrosis are normally present in Horner's syndrome. Pathologies which show central, preganglionic and postganglionic residence in sympathetic chain are present in its etiology. A 3-month-old girl baby was admitted to our clinic for ptosis in the left eye. Heterochromia, ptosis in the left eye, myosis and, ipsilateral anhidrosis were detected in her examination. In view of these findings, it seemed possible that her disease could be congenital Horner's syndrome. Brachial plexus injury due to birth trauma plays a major role in the etiology of congenital Horner's syndrome. There was not any birth trauma history in our patient. The patient was diagnosed to have neuroblastoma as a result of etiologic tests. In conclusion, Horner's syndrome can be the presenting sign of childhood neuroblastoma. Therefore, it is advisable to examine the oculosympathetic system in detail in order to leave out any underlying serious disorder.