Browsing by Author "Mentese, B"
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Item The Effect of Steroid Hormones on Cognitive Functions and Psychological Status in Healthy WomenKutlu, N; Mentese, B; Ulman, C; Demet, MM; Uyar, YItem Lateralization of the Fine Motor Skills in Right - and Left-handed Men and WomenMentese, B; Kutlu, NIntroduction: Motor performance is an important feature that can be measured to observe the development of the central and peripheral nervous system. Fine motor skill assessed by Morische-Leistungs-Serie (MLS) was studied in normal male and female right-handers and left-handers considering familial sinistrality and writing hand. Evaluations were conducted by measuring fine motor performance through the use of a modern computerized model. Materials and Methods: Hand preference was assessed by the Edinburgh Handedness Inventory Geschwind score (GS). Fine motor skills were measured by the MLS in the computerized Vienna Test System. Results: Left-handed volunteers had a significantly higher fine motor skills in both dominant and nondominant hands compared to right-handed volunteers. Conclusions: These results suggest that the contributions of the right and left cerebral hemispheres to the motor output of the brain depend on sex and more importantly, hand preference. It was determined that left handed subjects were more skillfull than right-handed subjects when dominant hands or weak hands were compared.Item Menstrual cycle phases, sex hormones and hand preference modulate nerve conduction velocity in healthy subjectsMentese, B; Kutlu, NThe aim of the present study was to investigate the relationship between hand preference and electrophysiological parameters in women menstrual cycle phases and men. Our study was conducted on 25 healthy, naturally cycling females and 30 healthy males between the ages of 18 and 25 who participated voluntarily. The female participants completed three test sessions (early follicular phase, the late follicular phase, and the luteal phase). We measured sex hormone concentrations in blood samples collected. Nerve conduction velocity was calculated using electromyography by stimulating the median nerves of the left and right hands of both the male and female participants. The median nerve conduction velocities of the dominant hands of both the males and females were higher than those of the non-dominant hands. The median nerve conduction velocity during the follicular phase of both the right-handed and left-handed females was higher than in the right-handed and left-handed males, while the latency was shorter. When we evaluated the nerve conduction velocities of the participants, we observed the effects of sexual dimorphism and lateralization. The findings suggested that nerve conduction velocity was found to be affected during the phases of the menstrual cycle in healthy female volunteers.Item Effects of ketamine/xylazine and urethane anesthesia on compound muscle action potential latency of gastrocnemius muscle in ratsMentese, B; Özel, H; Özbek, M; Kutlu, NObjective: Anesthetic agents, which are used in appropriate doses for the application of the experimental procedure in animals, relieve pain when applied in sufficient amounts as well as muscle relaxation. However, many anesthetics can alter the dynamics of neuromuscular systems. We aimed to compare the effects of two frequently used anesthetic agents on electromyographic parameters in rats. Materials and Methods: This study was performed on male Wistar albino rats aged 22-24 months. The animals were divided into two groups: urethane (1.5 gkg(-1), i.p; n = 6) and ketamine+xylazine (K+X) (80 mg/kg, i.p; n = 6). Under general anesthesia, rats were electrically stimulated with bipolar hook electrodes from both legs, and compound muscle action potential (CMAP) was recorded from the needle electrode of the gastrocnemius muscle. Motor nerve action potential latency (MNAPL) was measured from the sciatic nerve of the rats. Results: The results of electrodiagnostic findings related to two different anesthetics in the animals were compared, and CMAP parameters were found to differ between the groups. MNAPL in both the right and left legs was significantly reduced in the urethane group compared to the K+X group (P < 0.05). Conclusion: Urethane anesthesia may be a better choice than K+X anesthesia to evaluate nerve and muscle functions in animal electromyography studies.Item Sleep Disorders with Individuals in Prediction with Cerebral Lateralization Reasoning Ability, Evaluation of AttentionBastoklu, M; Mentese, B; Yilmaz, H; Kutlu, NItem Does Repeated Lipopolysaccharide Exposure in Early Adolescence Affect Behavior, Microglia and Synapse Plasticity in the Adult Brain?Yilmaz, G; Kutlu, N; Uluer, ET; Mentese, BItem Does repeated lipopolysaccharide exposure in early adolescence affect behavior, microglia, and synapse plasticity in the adult brain?Yilmaz, G; Kutlu, N; Uluer, ET; Mentese, B