Browsing by Author "Nadeau, KC"

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    ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020)
    Bousquet, J; Jutel, M; Akdis, CA; Klimek, L; Pfaar, O; Nadeau, KC; Eiwegger, T; Bedbrook, A; Ansotegui, IJ; Anto, JM; Bachert, C; Bateman, ED; Bennoor, KS; Berghea, EC; Bergmann, KC; Blain, H; Bonini, M; Bosnic-Anticevich, S; Boulet, LP; Brussino, L; Buhl, R; Camargos, P; Canonica, GW; Cardona, V; Casale, T; Chinthrajah, S; Akdis, M; Chivato, T; Christoff, G; Cruz, AA; Czarlewski, W; Del Giacco, S; Du, H; El-Gamal, Y; Fokkens, WJ; Fonseca, JA; Gao, YD; Gaga, M; Gemicioglu, B; Gotua, M; Haahtela, T; Halpin, D; Hamelmann, E; Hoffmann-Sommergruber, K; Humbert, M; Ilina, N; Ivancevich, JC; Joos, G; Khaitov, M; Kirenga, B; Knol, EF; Ko, FW; Koskinen, S; Kowalski, ML; Kraxner, H; Kudlay, D; Kuna, P; Kupczyk, M; Kvedariene, V; Latiff, AAH; Le, LT; Levin, M; Larenas-Linnemann, D; Louis, R; Masjedi, MR; Melén, E; Mihaltan, F; Milenkovic, B; Mohammad, Y; Morais-Almeida, M; Mullol, J; Namazova, L; Neffen, H; Nunes, E; O'Byrne, P; O'Hehir, R; O'Mahony, L; Ohta, K; Okamoto, Y; Onorato, GL; Panzner, P; Papadopoulos, NG; Passalacqua, G; Patella, V; Pawankar, R; Pham-Thi, N; Pigearias, B; Popov, TA; Puggioni, F; Regateiro, FS; Rolla, G; Rottem, M; Samolinski, B; Sastre, J; Schwarze, J; Sheikh, A; Scichilone, N; Soto-Quiros, M; Soto-Martinez, M; Sova, M; Nicola, S; Stelmach, R; Suppli-Ulrik, C; Taborda-Barata, L; To, T; Tomazic, PV; Toppila-Salmi, S; Tsiligianni, I; Usmani, O; Valiulis, A; Ventura, MT; Viegi, G; Vontetsianos, T; Wang, DY; Williams, S; Wong, GWK; Yorgancioglu, A; Zernotti, M; Zidarn, M; Zuberbier, T; Agache, I
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    Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence-Assisted ARIA Care Pathways (ARIA 2024)
    Bousquet, J; Schünemann, HJ; Sousa-Pinto, B; Zuberbier, T; Togias, A; Samolinski, B; Bedbrook, A; Czarlewski, W; Hofmann-Apitius, M; Litynska, J; Vieira, RJ; Anto, JM; Fonseca, JA; Brozek, J; Bognanni, A; Brussino, L; Canonica, GW; Cherrez-Ojeda, I; Cruz, AA; de las Vecillas, L; Dykewicz, M; Gemicioglu, B; Giovannini, M; Haahtela, T; Jacobs, M; Jacomelli, C; Klimek, L; Kvedariene, V; Larenas-Linnemann, DE; Louis, G; Lourenço, O; Leemann, L; Morais-Almeida, M; Neves, AL; Nadeau, KC; Nowak, A; Palamarchuk, Y; Palkonen, S; Papadopoulos, NG; Parmelli, E; Pereira, AM; Pfaar, O; Regateiro, FS; Savouré, M; Taborda-Barata, L; Toppila-Salmi, SK; Torres, MJ; Valiulis, A; Ventura, MT; Williams, S; Yepes-Nunez, JJ; Yorgancioglu, A; Zhang, L; Zuberbier, J; Latiff, AHA; Abdullah, B; Agache, I; Al-Ahmad, M; Al-Nesf, MA; Al Shaikh, NA; Amaral, R; Ansotegui, IJ; Asllani, J; Balotro-Torres, MC; Bergman, KC; Bernstein, JA; Bindslev-Jensen, C; Blaiss, MS; Bonaglia, C; Bonini, M; Bossé, I; Braido, F; Caballero-Fonseca, F; Camargos, P; Carreiro-Martins, P; Casale, T; Castillo-Vizuete, JA; Cecchi, L; Teixeira, MD; Chang, YS; Loureiro, CC; Christoff, G; Ciprandi, G; Cirule, I; Correia-de-Sousa, J; Costa, EM; Cvetkovski, B; de Vries, G; Del Giacco, S; Devillier, P; Dokic, D; Douagui, H; Durham, SR; Enecilla, ML; Fiocchi, A; Fokkens, WJ; Fontaine, JF; Gawlik, R; Gereda, JE; Gil-Mata, S; Giuliano, AFM; Gotua, M; Gradauskiene, B; Guzman, MA; Hossny, E; Hrubisko, M; Iinuma, T; Irani, C; Ispayeva, Z; Ivancevich, JC; Jartti, T; Jesenák, MS; Julge, K; Jutel, M; Kaidashev, I; Bennoor, KS; Khaltaev, N; Kirenga, B; Kraxner, H; Kull, I; Kulus, M; Kuna, P; Kupczyk, M; Kurchenko, A; La Grutta, S; Lane, S; Miculinic, N; Lee, SM; Tuyet, LLT; Lkhagvaa, B; Louis, R; Mahboub, B; Makela, M; Makris, M; Maurer, M; Melén, E; Milenkovic, B; Mohammad, Y; Moniuszko, M; Montefort, S; Moreira, A; Moreno, P; Mullol, J; Nadif, R; Nakonechna, A; Navarro-Locsin, CG; Neffen, HE; Nekam, K; Niedoszytko, M; Nunes, E; Nyembue, D; O'Hehir, R; Ollert, M; Ohta, K; Okamoto, Y; Okubo, K; Olze, H; Padukudru, MA; Palomares, O; Pali-Scholl, I; Panzner, P; Palosuo, K; Park, HS; Passalacqua, G; Patella, V; Pawankar, R; Pétré, B; Pitsios, C; Plavec, D; Popov, TA; Puggioni, F; Quirce, S; Raciborski, F; Ramonaité, A; Recto, M; Repka-Ramirez, S; Roberts, G; Robles-Velasco, K; Roche, N; Rodriguez-Gonzalez, M; Romualdez, JA; Rottem, M; Rouadi, PW; Salapatas, M; Sastre, J; Serpa, FS; Sayah, Z; Scichilone, N; Senna, G; Sisul, JC; Solé, D; Soto-Martinez, ME; Sova, M; Sozinova, O; Stevanovic, K; Ulrik, CS; Szylling, A; Tan, FM; Tantilipikorn, P; Todo-Bom, A; Tomic-Spiric, V; Tsaryk, V; Tsiligianni, I; Urrutia-Pereira, M; Rostan, MV; Sofiev, M; Valovirta, E; Van Eerd, M; Van Ganse, E; Vasankari, T; Vichyanond, P; Viegi, G; Wallace, D; Wang, DY; Waserman, S; Wong, G; Worm, M; Yusuf, OM; Zaitoun, F; Zidarn, M
    The traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients' resources and abilities to be experts in their own lives based on their lived experiences. Improving healthcare safety, quality, and coordination, as well as quality of life, is an important aim in the care of patients with chronic conditions. Person-centered care needs to ensure that people's values and preferences guide clinical decisions. This paper reviews current knowledge to develop (1) digital care pathways for rhinitis and asthma multimorbidity and (2) digitally enabled, person-centered care.(1) It combines all relevant research evidence, including the so-called real-world evidence, with the ultimate goal to develop digitally enabled, patient-centered care. The paper includes (1) Allergic Rhinitis and its Impact on Asthma (ARIA), a 2-decade journey, (2) Grading of Recommendations, Assessment, Development and Evaluation (GRADE), the evidence-based model of guidelines in airway diseases, (3) mHealth impact on airway diseases, (4) From guidelines to digital care pathways, (5) Embedding Planetary Health, (6) Novel classification of rhinitis and asthma, (7) Embedding real-life data with population-based studies, (8) The ARIA-EAACI (European Academy of Allergy and Clinical Immunology) strategy for the management of airway diseases using digital biomarkers, (9) Artificial intelligence, (10) The development of digitally enabled, ARIA person-centered care, and (11) The political agenda. The ultimate goal is to propose ARIA 2024 guidelines centered around the patient to make them more applicable and sustainable. (c) 2024 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. This is an open access article under the CC BY license (http:// creativecommons.org/licenses/by/4.0/).
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    COVID-19 pandemic: Practical considerations on the organization of an allergy clinic-An EAACI/ARIA Position Paper
    Pfaar, O; Klimek, L; Jutel, M; Akdis, CA; Bousquet, J; Breiteneder, H; Chinthrajah, S; Diamant, Z; Eiwegger, T; Fokkens, WJ; Fritsch, HW; Nadeau, KC; O'Hehir, RE; O'Mahony, L; Rief, W; Sampath, V; Schedlowski, M; Torres, MJ; Traidl-Hoffmann, C; Wang, DY; Zhang, L; Bonini, M; Brehler, R; Brough, HA; Chivato, T; Del Giacco, SR; Dramburg, S; Gawlik, R; Gelincik, A; Hoffmann-Sommergruber, K; Hox, V; Knol, EF; Lauerma, A; Matricardi, PM; Mortz, CG; Ollert, M; Palomares, O; Riggioni, C; Schwarze, J; Skypala, I; Untersmayr, E; Walusiak-Skorupa, J; Ansotegui, IJ; Bachert, C; Bedbrook, A; Bosnic-Anticevich, S; Brussino, L; Canonica, GW; Cardona, V; Carreiro-Martins, P; Cruz, AA; Czarlewski, W; Fonseca, JA; Gotua, M; Haahtela, T; Ivancevich, JC; Kuna, P; Kvedariene, V; Larenas-Linnemann, DE; Latiff, AHA; Mäkelä, M; Morais-Almeida, M; Mullol, J; Naclerio, R; Ohta, K; Okamoto, Y; Onorato, GL; Papadopoulos, NG; Patella, V; Regateiro, FS; Samolinski, B; Suppli Ulrik, C; Toppila-Salmi, S; Valiulis, A; Ventura, MT; Yorgancioglu, A; Zuberbier, T; Agache, I
    BackgroundThe coronavirus disease 2019 (COVID-19) has evolved into a pandemic infectious disease transmitted by the severe acute respiratory syndrome coronavirus (SARS-CoV-2). Allergists and other healthcare providers (HCPs) in the field of allergies and associated airway diseases are on the front line, taking care of patients potentially infected with SARS-CoV-2. Hence, strategies and practices to minimize risks of infection for both HCPs and treated patients have to be developed and followed by allergy clinics. MethodThe scientific information on COVID-19 was analysed by a literature search in MEDLINE, PubMed, the National and International Guidelines from the European Academy of Allergy and Clinical Immunology (EAACI), the Cochrane Library, and the internet. ResultsBased on the diagnostic and treatment standards developed by EAACI, on international information regarding COVID-19, on guidelines of the World Health Organization (WHO) and other international organizations, and on previous experience, a panel of experts including clinicians, psychologists, IT experts, and basic scientists along with EAACI and the Allergic Rhinitis and its Impact on Asthma (ARIA) initiative have developed recommendations for the optimal management of allergy clinics during the current COVID-19 pandemic. These recommendations are grouped into nine sections on different relevant aspects for the care of patients with allergies. ConclusionsThis international Position Paper provides recommendations on operational plans and procedures to maintain high standards in the daily clinical care of allergic patients while ensuring the necessary safety measures in the current COVID-19 pandemic.
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    Development and validation of combined symptom-medication scores for allergic rhinitis*
    Sousa-Pinto, B; Azevedo, LF; Jutel, M; Agache, I; Canonica, GW; Czarlewski, W; Papadopoulos, NG; Bergmann, KC; Devillier, P; Laune, D; Klimek, L; Anto, A; Anto, JM; Eklund, P; Almeida, R; Bedbrook, A; Bosnic-Anticevich, S; Brough, HA; Brussino, L; Cardona, V; Casale, T; Cecchi, L; Charpin, D; Chivato, T; Costa, EM; Cruz, AA; Dramburg, S; Durham, SR; De Feo, G; van Wijk, RG; Fokkens, WJ; Gemicioglu, B; Haahtela, T; Illario, M; Ivancevich, JC; Kvedariene, V; Kuna, P; Larenas-Linnemann, DE; Makris, M; Mathieu-Dupas, E; Melén, E; Morais-Almeida, M; Mösges, R; Mullol, J; Nadeau, KC; Nhan, PH; O'Hehir, R; Regateiro, FS; Reitsma, S; Samolinski, B; Sheikh, A; Stellato, C; Todo-Bom, A; Tomazic, PV; Toppila-Salmi, S; Valero, A; Valiulis, A; Ventura, MT; Wallace, D; Waserman, S; Yorgancioglu, A; Vries, G; Eerd, M; Zieglmayer, P; Zuberbier, T; Pfaar, O; Fonseca, JA; Bousquet, J
    Background Validated combined symptom-medication scores (CSMSs) are needed to investigate the effects of allergic rhinitis treatments. This study aimed to use real-life data from the MASK-air(R) app to generate and validate hypothesis- and data-driven CSMSs. Methods We used MASK-air(R) data to assess the concurrent validity, test-retest reliability and responsiveness of one hypothesis-driven CSMS (modified CSMS: mCSMS), one mixed hypothesis- and data-driven score (mixed score), and several data-driven CSMSs. The latter were generated with MASK-air(R) data following cluster analysis and regression models or factor analysis. These CSMSs were compared with scales measuring (i) the impact of rhinitis on work productivity (visual analogue scale [VAS] of work of MASK-air(R), and Work Productivity and Activity Impairment: Allergy Specific [WPAI-AS]), (ii) quality-of-life (EQ-5D VAS) and (iii) control of allergic diseases (Control of Allergic Rhinitis and Asthma Test [CARAT]). Results We assessed 317,176 days of MASK-air(R) use from 17,780 users aged 16-90 years, in 25 countries. The mCSMS and the factor analyses-based CSMSs displayed poorer validity and responsiveness compared to the remaining CSMSs. The latter displayed moderate-to-strong correlations with the tested comparators, high test-retest reliability and moderate-to-large responsiveness. Among data-driven CSMSs, a better performance was observed for cluster analyses-based CSMSs. High accuracy (capacity of discriminating different levels of rhinitis control) was observed for the latter (AUC-ROC = 0.904) and for the mixed CSMS (AUC-ROC = 0.820). Conclusion The mixed CSMS and the cluster-based CSMSs presented medium-high validity, reliability and accuracy, rendering them as candidates for primary endpoints in future rhinitis trials.