Browsing by Author "Nihat Sapan"

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    Clinical characteristics of patients requiring lung transplantation referral in national cystic fibrosis registry data
    (2023) Ayşen Bingöl; ERDEM BAŞARAN; Gökçen Dilşa Tuğcu; Sanem Eryilmaz Polat; Abdulhamit Çollak; Selcuk Uzuner; Nihat Sapan; Zeynep Reyhan Onay; Tugba Ramasli Gursoy; Nural Kiper; Nagehan Emiralioglu; Haluk Cezmi cokugras; Sebnem Ozdogan; Pervin Korkmaz; Sukru Cekic; ZEYNEP ÜLKER TAMAY; Azer Kilic Baskan; Mehmet Alp Kose; Ebru Damadoglu; Tugba Sismanlar Eyuboglu; Ayse Tana Aslan; Gonca KILIÇ; NAZAN ÇOBANOGLU; SEVGI PEKCAN; UĞUR ÖZÇELİK; Deniz Dogru; GUZIN CINEL; Ebru Yalcin; Hadice Selimoğlu Şen; velat ŞEN; Gökçen ünal; Asli imran YILMAZ; Ayse Ayzit Kilinc; Hakan Yazan; Ayse Senay Sasihuseyinoglu; Dilek ÖZCAN; Derya Ufuk Altintas; Gökçen Kartal Öztürk; Esen Demir; Ilim Irmak; Ali Özdemir; koray harmancı; Melih Hangul; Hasan Yuksel; Gizem ÖZCAN; erdem topal; Demet Can; Gönül Çaltepe; Mehmet KILIÇ; Erkan CAKIR
    Background. We aimed to determine the number of cystic fibrosis (CF) patients recorded in the Cystic Fibrosis Registry of Türkiye (CFRT) who were in need of lung transplantation (LT) referral and examine clinical differences between patients who were LT candidates due to rapid forced expiratory volume in one second (FEV₁) decline and LT candidates without rapid FEV₁ decline in the last year to identify a preventable cause in patients with such rapid FEV₁ decline. Methods. All CF patients recorded in the CFRT in 2018 were evaluated in terms of LT. Patients were divided into those with FEV₁ below 50% and in need of LT due to a decrease of 20% or more in the previous year (Group 1) and those who did not have FEV₁ decline of more than 20% in the previous year but had other indications for LT (Group 2). Demographic and clinical features were compared between the two groups. Results. Of 1488 patients registered in CFRT, 58 had a need for LT. Twenty patients were included in Group 1 and others in Group 2. Our findings did not reveal any significant variations in treatment, chronic infection status, or complications between the two groups. The average weight z-score was significantly higher in Group 1. Positive correlations were detected between weight z-score and FEV₁ in 2017 in Group 1 and between FEV₁ values in 2017 and 2018 in Group 2. Conclusions. There appears to be a relationship between the nutritional status and weight z-scores of CF patients and pulmonary function, which may indirectly affect the need for lung transplantation referral.