Browsing by Author "Oral, T"

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    Development, reliability and validity of bipolar disorder functioning questionnaire
    Aydemir, O; Eren, I; Savas, H; Kalkan-Oguzhanoglu, N; Kocal, N; Devrimci-Ozguven, H; Akkaya, C; Devrim-Basterzi, A; Karlidag, R; Yenilmez, C; Ozerdem, A; Kora, K; Tamam, L; Gulseren, S; Oral, T; Vahip, S
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    Development of a questionnaire to assess inter-episode functioning in bipolar disorder: Bipolar disorder functioning questionnaire
    Aydemir, Ö; Eren, I; Savas, H; Oguzhanoglu, NK; Koçal, N; Özgüven, HD; Akkaya, C; Basterzi, AD; Karlidag, R; Yenilmez, Ç; Özerdem, A; Kora, K; Tamam, L; Gülseren, S; Oral, T; Vahip, S
    Objective: Even though quality of life and functioning are topics that are point of interest, they are not assessed adequately in mood disorders. In this study, it is aimed to develop a functioning assessment scale in bipolar disorder. Method: Bipolar Disorder Functioning Questionnaire (BDFQ) is developed by the Scientific Section for Mood Disorders of the Psychiatric Association of Turkey. The questionnaire contains 58 items, and consists of eleven subscales: emotional functioning, intellectual functioning, sexual functioning, feelings of stigmatization, social withdrawal household relations, relations with friends, participation to social activities, daily activities and hobbies, taking initiative and self sufficiency, and occupation. Results: In this study, 252 remitted bipolar patients from 15 centers were included. In addition, thirty subjects without any lifetime psychiatric, neurological or physical disease were recruited. The mean age of the patients was 38.6 +/- 12.1 and 56% (n=141) were female. The mean duration of the bipolar disorder was 11.9 +/- 9.2 years, and 91.3% of the patients were diagnosed to have bipolar I disorder. In the reliability analyses, after the exclusion of six items with low reliability coefficients, The Cronbach alpha coefficient was calculated to be 0.91. The item-total scale correlations were between 0.22-0.86. In test-retest reliability, the correlation between the two ratings was high (r=0.82, p<0.0001). In validity analyses, 13 factors were obtained representing 65.1% of the total variance in exploratory factor analysis. In confirmatory factor analysis, 11 domains fit the model with a RMSEA of 0.061. BDFQ significantly correlated with GAF (r=0.428, p<.0001). BDFQ also showed significantly negative correlation with HAM-D (r=-0.541, p<0.0001) and YMRS (r=-0.365, p<0.0001). It discriminated the patients (mean score=111.8 +/- 15.2) from the healthy subjects (mean score=121.4 +/- 10.4) well (t=-2.300, p=0.038). Conclusion: With the six items excluded, it is suggested that the 52-item BDFQ is a reliable and valid instrument in the assessment of functioning in bipolar disorder.
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    Reliability and Validity Study of the Turkish Version of Hypomania Checklist-32-Revised
    Vahip, S; Aydemir, Ö; Akkaya, C; Altinbas, K; Kora, K; Dikici, D; Akdeniz, F; Kalayci, F; Oral, T; Vahip, I; Alkan, M; Angst, J
    Objective: In this study, it is aimed to evaluate the reliability and validity of the Turkish version of Hypomania Checklist-32-Revised. Method: The study was carried out with 80 patients diagnosed with bipolar I disorder, 26 patients diagnosed with bipolar II disorder and 42 patients diagnosed with major depressive disorder attending the out- and in-patient psychiatry departments of three university hospitals and one training hospital, and 116 healthy volunteers consisting of university students. Mean duration of illness was 15,1 years for the bipolar disorder group, and 9,3 years for the major depressive disorder group. For concurrent validity, Mood Disorder Questionnaire was used. In the statistical analysis, internal consistency coefficient, item-total score correlation coefficients, exploratory factor analysis, correlation with concurrent scale and ROC curve were calculated. Results: Translation into Turkish and back-translation into English of Hypomania Checklist-32-Revised were performed and thus the semantic harmony of the scale was obtained. In the internal consistency, Cronbach alpha coefficient was 0,914 and item-total score correlations were between 0,235-0.743. Solely the coefficient of item #23 was found as 0,110. In factor analysis, six factors were obtained but a two-factor solution representing 44,5% of the total variance was accepted and first factor represents overactivity and being expansive, second factor represents impulsivity and risky behaviors. Correlation of Hypomania Checklist-32-R with Mood Disorder Questionnaire was r=0,379. In the ROC analysis, the cut off point of the scale was calculated as 14 with a sensitivity of 71,0 and specificity of 69,8. The scale discriminates well between the bipolar group, and depressive and control groups. Conclusion: Hypomania Checklist-32-Revised developed for screening hypomania is reported to be reliable and valid in Turkish after cutting out item #23.