Browsing by Author "Orguc, S"
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Item THE ASSOCIATION SERUM INTERLEUKIN 17 AND INTERLEUKIN 23 LEVELS WITH CLINICAL AND RADIOLOGICAL PARAMETERS IN RHEUMATOID ARTHRITIS PATIENTSUcar, U; Duruoz, MT; Guvenc, Y; Orguc, SItem Benign Versus Malignant Vertebral Compression, Chemical Shift MR Imaging, Is It Useful?Ovali, GY; Düzgün, F; Farasat, M; Orguc, SObjectives: The aim of this study was to evaluate the diagnostic accuracy of chemical shift imaging in vertebral compression. Patients and Methods: Forty-nine patients with vertebral compression with suspected malignancy or history of trauma were included in this study. MRimaging of the spine with standard conventionalMRsequences and additional chemical shift imaging was done with 1.5 Tesla MR Unit. Regions of interest (ROI) were placed on the abnormal marrow of compressed vertebrae both on the opposed phase and on the matching in phase images and signal intensity (SI) ratio values (SI out-phase/SI-in phase) were calculated. Results: Forty-nine patients had 68 spine lesions, consisting of 49 benign and 19 malignant fractures. Student t test, receiver operating characteristic (ROC) analysisandinterclass correlation test were used statistically. MeanSI ratio of benign vertebral compression (0. 68 +/- 0.29, range 0.13 - 1.53) was significantly lower than malignant SI ratio values (1.06 +/- 0.10, range 0.96 -1.35). With student t-test, there was significant difference between benign compressions compared to malignant compressions (P < 0.001). Receiver operating characteristic (ROC) curve analysis was used to determine the optimal cut off value in malignant and benign lesion definition. The optimal SI ratio cut off value was found to be 0.96 for separating benign and malignant vertebral compression. The area under the curve (AUC) value was observed as 0.92 (95% confidence interval [CI] = 0.86-0.99). According to that cutoff value, sensitivity was 100% (95% CI = 82.35% -100%) and the specificity was 86% (95% CI = 72.76% -94.06%). Interobserver reliability was studied with intraclass correlation and results were statistically significant with intraclass correlation coefficient (ICC) as 0.85 (P < 0.05). Conclusions: There is significant difference in signal values between benign and malignant compression fractures in chemical shift MR imaging. Chemical shift MR imaging has much additive data to conventional MRI in vertebral compression.Item Magnetic Resonance Imaging and Clinical Outcomes of Laser Therapy, Ultrasound Therapy, and Extracorporeal Shock Wave Therapy for Treatment of Plantar Fasciitis: A Randomized Controlled TrialUlusoy, A; Cerrahoglu, L; Orguc, SWe determined and compared the effectiveness of low-level laser therapy (LLLT), therapeutic ultrasound (US) therapy, and extracorporeal shock wave therapy (ESWT) using magnetic resonance imaging (MRI). We performed a randomized, prospective, comparative clinical study. A total of 60 patients with a diagnosis of chronic plantar fasciitis were divided randomly into 3 treatment groups: group 1 underwent 15 sessions of LLLT (8 J/cm(2); 830 nm); group 2 underwent 15 sessions of continuous US (1 mHz; 2 W/cm(2)); and group 3 underwent 3 sessions of ESWT (2000 shocks). All patients were assessed using the visual analog scale (VAS), heel tenderness index (HTI), American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot scale, Roles-Maudsley score, and MRI before and 1 month after treatment. The primary efficacy success criterion was the percentage of decrease in heel pain of >60% from baseline at 1 month after treatment for >= 2 of the 3 heel pain (VAS) measurements. Significant improvement was measured using the mean VAS, AOFAS scale, and HTI scores for all 3 groups. The thickness of the plantar fascia had decreased significantly on MRI in all 3 groups. The treatment success rate was 70.6% in the LLLT group, 65% in the ESWT group, and 23.5% in the US group. LLLT and ESWT proved significantly superior to US therapy using the primary efficacy criterion (p = .006 and p = .012, respectively), with no significant difference between the LLLT and ESWT groups (p > .05). The treatment of chronic plantar fasciitis with LLLT and ESWT resulted in similar outcomes and both were more successful than US therapy in pain improvement and functional outcomes. (C) 2017 by the American College of Foot and Ankle Surgeons. All rights reserved.Item Primary Tumors of the SpineOrguc, S; Arkun, RSpinal tumors consist of a large spectrum of various histologic entities. Multiple spinal lesions frequently represent known metastatic disease or lymphoproliferative disease. In solitary lesions primary neoplasms of the spine should be considered. Primary spinal tumors may arise from the spinal cord, the surrounding leptomeninges, or the extradural soft tissues and bony structures. A wide variety of benign neoplasms can involve the spine including enostosis, osteoid osteoma, osteoblastoma, aneurysmal bone cyst, giant cell tumor, and osteochondroma. Common malignant primary neoplasms are chordoma, chondrosarcoma, Ewing sarcoma or primitive neuroectodermal tumor, and osteosarcoma. Although plain radiographs may be useful to characterize some spinal lesions, magnetic resonance imaging is indispensable to determine the extension and the relationship with the spinal canal and nerve roots, and thus determine the plan of management. In this article we review the characteristic imaging features of extradural spinal lesions.Item Doppler Sonographic Findings in Testicular MicrolithiasisSerter, S; Orguc, S; Gumus, B; Ayyildiz, V; Pabuscu, YObjective The aim of this prospective study was to compare the resistive index (RI) values, which is a parameter of testicular parenchymal perfusion, in testicular microlithiasis (TM) cases and normal cases. Materials and Methods 2179 volunteers, all healthy men (17-42 years of age) from the Annual Army Reserve Officer Training Corps training camp were included in the study. A screening scrotal ultrasound was performed and all men diagnosed with TM underwent a scrotal Doppler ultrasonography scan (US). US examinations were performed for subjects with TM and without TM as a control group and RI was determined. Results 53 men with TM were identified in the 2179 US. Spectral Doppler examination was applied to 50 randomly selected cases (100 testicles) without TM and 92 testicles with TM, 39 cases (78 testicles) with bilateral and 14 cases with unilateral involvement. However, 48 normal testicles (17 bilateral and 14 unilateral) and 47 testicles with TM (15 bilateral and 17 unilateral, 10 of which were cases with bilateral TM) where flow from the centripetal artery could be obtained and analyzed were included in the statistical analysis for resistive indices There was no significant difference regarding the RI and spectral examinations between subjects with and without TM An interesting finding was the twinkling artifact observed in three cases. Conclusion: Microliths did not alter the RI values and thus had no influence on testicular perfusion on Doppler US examinationItem Testicular Tumor and Testicular Microlithiasis: Doppler US ApproachSerter, S; Orguc, S; Tuncyurek, O; Gümü, B; Tarhan, S; Ayyildiz, V; Pabuscu, YItem Contribution of Advanced Magnetic Resonance Imaging Techniques in Diagnosis of Breast LesionsBasara, I; Orguc, S; Coskun, TObjectives: To determine the diagnostic contribution of diffusion weighted imaging (DWI) and magnetic resonance spectroscopy (MRS) identified either with mammography, ultrasonography or conventional enhanced magnetic resonance imaging (MRI) to cases with palpable breast lesions or for routine control Design: Prospective study Setting: Department of Radiology, Celal Bayar University, Turkey Subjects and Methods: Fifty female patients who applied to the clinic between November 2009 and April 2010 with different indications were included. We applied conventional breast MRI with the routine sequences. We added DWI and BREASE (MRS). After MRI examination postprocessing applications were applied. Intervention: Analysis of contribution of advanced techniques in breast lesions diagnosis Main Outcome Measure: Determining the value of DWI and MRS of breast lesions, which may be useful in improving the specificity Results: Fifty-two breast lesions in 37 cases were evaluated. In DWI when cut off apparent coefficient diffusion (ACD) value was accepted as 1.44 x 10.3 mm(2)/sn, the sensitivity was found to be 91.3% and the specifity was 62.1% in discriminating malignant and benign lesions. When the lesions which have choline peak at 3.2 ppm were accepted as malignant and lesions which do not have choline peak were accepted as benign lesions in spectroscopic examination, the specifity was 80%, the sensitivity was 31.8%, negative predictive value (NPV) was 44.4% and positive predictive value (PPV) was found to be 70%. Conclusions: Our specifity was compatible with that in the literature but sensitivity and negative ppv were lower than reported in the literature. According to ADC values, the findings in our study were compatible with the literature.Item Comparison of clinical outcomes and repair integrity after arthroscopic versus mini-open rotator cuff repair: An observational studyTosyali, HK; Kaya, H; Hancioglu, S; Tamsel, I; Orguc, S; Tekustun, F; Kayikci, K; Kucuk, L; Ozalp, TThis study aimed to evaluate the differences between mini-open (MO) and arthroscopic (ART) repair procedures for rotator cuff tendon tears in terms of clinical and radiological outcomes. This retrospective study included 59 patients, and data were collected prospectively. Patients with full-thickness rotator cuff tears were randomized to undergo MO or ART repair at 2 centers by 2 surgeons between January 2012 and December 2017. Data were collected 3 weeks before surgery and 6 and 12 months after surgery. Physical function was assessed using the American Shoulder and Elbow Surgeons index, VAS, and Constant scoring system. Radiological outcomes were assessed using the Sugaya classification, adapted for ultrasound. Changes between baseline and follow-up were compared between the 2 groups. Fifty-nine patients who underwent ART or MO rotator cuff repair were included in this study. The 2 groups had similar demographic characteristics and preoperative baseline parameters. Both the MO and ART groups showed statistically significant improvement in outcome parameters (P <= .0001); however, cuff repair integrity was significantly better in the ART group (P = .023). All other improvements in the patient-derived parameters were equivalent. None of the patients in either group required revision surgery. According to the results of our retrospective study, MO and ART rotator cuff repair are effective and viable options for surgeons to repair rotator cuff tears. There were no differences in objective and subjective outcomes between the full ART and MO techniques for rotator cuff tears. Surgeons should choose a technique with which they are more familiar.Item Biochemical and radiologic predictors of hepatic steatosis in living liver donorsKarasu, Z; Kilic, M; Orguc, S; Nart, D; Kobat, A; Akarca, U; Aydogdu, S; Demirbas, T; Akyildiz, M; Arikan, C; Tokat, YItem Rhinocerebral mucormycosisOrguc, S; Yücetürk, AV; Demir, MA; Goktan, CWe report a case of rhinocerebral mucormycosis associated with an abscess in the lateral aspect of the pons associated with perineural spread of disease via the trigeminal nerve. Contrast enhanced MRI was useful in depicting the extent of the disease and suggesting perineural spread. A pathological diagnosis of mucormycosis was established by means of rhino-orbital punch biopsy. (c) 2005 Elsevier Ltd. All rights reserved.Item Elongated Styloid Process and Cervical SpondylosisUnlu, Z; Orguc, S; Eskiizmir, G; Aslan, A; Bayindir, PBackground: Dysphagia, is a significant sign of many different lesions in upper digestive system especially in proximal esophagus. Tumors, gastroesophageal reflux, achalasia and extrinsic compressions are the most common causes that may lead to dysphagia in geriatric population. Cervical osteophyte induced dysphagia, is one of the uncommon reasons of dysphagia, therefore other causes of dysphagia must be excluded to establish the exact diagnosis. Eagle syndrome is one of the considerable reason which may lead to misdiagnosis in patients with cervical osteophytes. In this case report, we represent four patients who had dysphagia due to anteriorly located cervical osteophytes and evaluate the patients with special reference to Eagle syndrome. Material and methods: After a detailed anamnesis and ENT examination, cervical plain radiographs in four projections and Towne radiographs were obtained for every patient. After that, magnetic resonance imaging (MRI) of cervical spine and barium swallowing studies were performed to evaluate the presence of esophageal compression. Results: Eagle syndrome was excluded due to absence of other symptoms and physical signs, eventhough unilateral or bilateral elongation of styloid processes was found in all of the patients. Conclusion: Cervical osteophytes induced dysphagia is a rare clinical entity, diagnosis should be done by a careful examination, intensive radiologic evaluation. Moreover, all the other causes like Eagle syndrome should be excluded during the diagnosis of cervical osteophyte induced dysphagia.Item The role of phonophoresis in dyshpagia due to cervical osteophytesUnlu, Z; Orguc, S; Eskiizmir, G; Aslan, A; Tasci, SObjective: Treatment of patients with anterior cervical osteophytes causing dysphagia includes conservative treatment with anti-inflammatory drugs, muscle relaxants, antibiotics, and an appropriate soft diet. Physical therapy with its advantages may be an alternative method in the treatment, which was not reported previously. Case description: Phonophoresis therapy is applied in nine patients with dysphagia due to cervical osteophytes. Results: The symptom of dysphagia regressed in various degrees in all patients after phonophoresis therapy. Conclusions: Phonophoresis might be an alternative method for the non-steroidal anti-inflammatory drug (NSAID) treatment in patients with dysphagia due to cervical osteophytes.Item Bilateral plasmacytoma of the breastOrguc, S; Akin, M; Aydogdu, I; Nese, NItem A case of endometrial stromal sarcoma with curvilinear calcificationPekindil, G; Tuncyurek, O; Orguc, S; Inceboz, U; Kandiloglu, AR; Caglar, HBackground. Although many histopathological, clinical, and imaging findings of ESS have been described, intense calcifications have not been reported previously. Case. A 54-year-old female was admitted with vaginal bleeding and abdominal pain. Gynecologic examination revealed a huge, firm pelvic mass extending up to the epigastrium. Transabdominal ultrasonography and computed tomography demonstrated a well-demarcated uterine mass containing heterogeneous solid and cystic areas and a centric curvilinear calcification. Histopathological diagnosis was established as undifferentiated high-grade endometrial stromal sarcoma. Conclusion. Endometrial stromal sarcomas should be considered in the differential diagnosis of uterine masses containing curvilinear calcifications. (c) 2005 Elsevier Inc. All rights reserved.Item Assessment of mammographic density changes on plain film mammograms in postmenopausal women on hormone replacement therapyOrguc, S; Goktan, C; Ovali, GY; Karaer, O; Oruc, SBackground & objectives: Marnmographic screening is an effective tool for the early detection of breast cancer. Hormone replacement therapy (HRT) has been shown to increase mammographic density and thus may hinder early detection of small tumours. We undertook this study to determine and compare the frequency and degree of change in mammographic density in postmenopausal women in HRT using two different methods: the classical Wolfe classification and a new semiquantitative method, which we named as the comparison wheel. Methods: This study included 285 women, 206 under hormone treatment, and 79 control subjects. All women underwent baseline mammographic study before the beginning of treatment. Mean interval of the follow up mammograms was 16 months. The methods were compared in evaluating the effects of three types of hormone therapies on marnmographic density. Results: The frequency of change was only significant in the combined hormone replacement group when Wolfe classification was used. However, the frequency of increase in density (estrogen group 21 %, combined therapy group 42%, tibolone group 28%) was markedly higher when the comparison wheel was used. The inter-rater Kappa value was calculated as 0.977 for the first and 0.957 for the second readings of the two radiologists for the comparison wheel, and 0.973 and 0.968 for the Wolfe classification. The intra-rater Kappa values were determined as 0.972 and 0.957 for the first and and 0.963 and 0.926 for the second radiologist for comparison wheel and Wolfe classification respectively. Interpretation & conclusion: Our findings indicate that the estimated increase of mammographic density depends on the selected hormone regimen, as well as the method of evaluation. The comparison wheel is a serniquantitative method of evaluating changes of mammographic density and is sensitive and reproducible with high inter- and intra- rater Kappa values. This method can be used as an alternative for comparison of digital mammographic applications in the future.Item Unusual long bone and metacarpo-carpal abnormalities in a case of pseudo-pseudohypoparathyroidismUnlu, Z; Orguc, S; Ovali, GY; Bayindir, PA case of pseudo-pseudohypoparathyroidism (PPH) with shortening of the left femur and tibia and coalition of the base of the fourth metacarpals with capitatum and hamatum in bilateral wrist joints was presented. Involvement of the fourth digits both in hands and feet were more prominent on the left side, with shortening of the left leg.Item Magnetic resonance imaging findings in a case of remitting seronegative symmetrical synovitis with pitting edemaUnlu, Z; Orguc, S; Ovali, GY; Tarhan, S; Dayan, I; Angin, AWe describe a case of remitting seronegative symmetrical synovitis with pitting edema (RS3PE syndrome) in a 66-year-old man. This report discusses magnetic resonance imaging findings of RS3PE syndrome and the changes after steroid therapy.Item Ultra fast resolution of acute post-traumatic subdural haematomaMirzai, H; Yaldiz, C; Eminoglu, M; Orguc, SItem Are drains useful for lumbar disc surgery? A prospective, randomized clinical studyMirzai, H; Eminoglu, M; Orguc, SObjective: In this prospective, observer-masked clinical study, we evaluated if insertion of a drain had a significant role in decreasing the existence and the size of postoperative epidural hematoma, which is believed to be a factor causing epidural fibrosis in patients undergoing lumbar discectomy. Method: Fifty patients undergoing lumbar disc surgery were randomly assigned to two groups: with or Without insertion of a drain in the epidural space. A drain was inserted in 22 patients, whereas 28 were left without a drain. All patients were evaluated, by means of magnetic resonance imaging (MRI) oil the first postoperative day, specifically looking for the existence and the size of epidural hematoma. The size of epidural hematoma was graded as none, minimal, moderate, or prominent. The patients were clinically examined preoperatively and at the follow-up of 6 months by Oswestry Disability Index and recurrence of pain. A follow-up MRI was repeated at 6 months, and the subsequent development of epidural fibrosis was evaluated. Results: Epidural hematoma was detected in 36% of patients with a drain and in 89% of patients without a drain (P = 0.000). There were significant less number of minimum, moderate, and prominent sized hematomas in the group with a drain (P = 0.000). On the 6-month follow-up, epidural fibrosis was found in 58.3% of patients without a drain and in 31.6% of patients with a drain (P = 0.08). Late clinical outcome (improvement in Oswestry Index and no recurrent pain) was better in the group with drain, but not statistically significant (P = 0.4). Conclusions: Occurrence of hematoma in the epidural space is common after lumbar disc surgery even if meticulous hemostasis has been achieved. Insertion of a drain decreases both the incidence and the size of hematoma on the first postoperative day as detected by MRL This may have practical implications for the prevention of significant postoperative fibrosis and obtaining better surgical outcome.Item Transient left paraduodenal herniaOvali, GY; Orguc, S; Unlu, M; Pabuscu, YA 52-year-old woman with acute deterioration of recurrent abdominal pain was admitted to the hospital. Spiral computed tomography (CT) of abdomen was performed. A left paraduodenal hernia was identified on CT. There was no clinical sign or imaging finding suggesting intestinal obstruction or mesenteric ischemia. She refused surgical intervention since her pain was intermittant and decreasing. On the fifth day of hospitalization the patient's pain resolved completely and the follow-up CT demonstrated regression of the herniation. (c) 2005 Elsevier Ltd. All rights reserved.