Browsing by Author "Oto A."

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    A multicentre study of abdominal aorta diameters in a Turkish population
    (Cambridge Medical Publications, 2002) Sariosmanoglu N.; Ugurlu B.; Karacelik M.; Tuzun E.; Yorulmaz I.; Manisali M.; Oto A.; Besim A.; Oto O.
    The aim of this study was to determine the normal values for aortic diameters and the prevalence of aortic dilatation in a mixed Turkish population. Between March 1998 and May 2000, patients who were undergoing abdominal ultrasonography examination for pathologies not involving the aorta, in three different cities, were enrolled into the study prospectively. The anterior posterior aortic diameters were measured at the subdiaphragmatic and aortic bifurcation levels using ultrasonography. A total of 596 patients were included (302 females, 294 males). The mean age was 48 ± 16 years (range, 6 - 88 years). The mean aortic diameter in the whole group was 19.0 ± 3.9 mm (10 - 45 mm) at the subdiaphragmatic level and 15.7 ± 3.6 mm (9 - 65 mm) at the aortic bifurcation level. The mean subdiaphragmatic aortic diameter was 18 ± 3 mm in females and 19 ± 4 mm in males. The mean aortic diameters at the bifurcation level was 15 ± 3 mm in females and 16 ± 4 mm in males. An aortic bifurcation diameter > 30 mm was encountered in 0.6% of the population. This ratio increased to 1.8% in patients over 55 years of age, regardless of sex. A subdiaphragmatic aorta diameter above 30 mm was observed in 1.2% of the population. In patients over the age of 55 years, this ratio increased to 2.7% (3.6% in males and 1.9% in females). In this national study, the subdiaphragmatic aortic diameters were similar to mean values reported in the world literature. The mean aortic bifurcation diameters were generally lower when compared with the literature, which may be due to difficulties in standardization of the measurements. Aneurysmal dilatation rates in this study also conform to those reported in studies conducted in other countries. Considering the significant number of patients with aneurysmal dilatation of the aorta in the elderly population, we believe it would be prudent to evaluate the aorta in all patients undergoing abdominal ultrasonographic examination.
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    Increased P Wave Dispersion and Maximum P Wave Duration after Hemodialysis
    (2004) Tezcan U.K.; Amasyali B.; Can I.; Aytemir K.; Köse S.; Yavuz I.; Kursaklioglu H.; Işik E.; Demirtaş E.; Oto A.
    Background: Atrial fibrillation is a frequent arrhythmia in patients undergoing hemodialysis. The consequences of hemodialysis on P wave durations and P wave dispersion have not been fully understood. The objective of this study was to study the effect of dialysis on P wave maximum (Pmax), P wave minimum (Pmin), and P wave dispersion (Pd). Methods: We studied Pmax, Pmin, and Pd in 32 patients (17 men and 15 women, mean age 54 ± 18 years) with chronic renal failure undergoing hemodialysis. The difference between maximum and minimum P wave duration was calculated and defined as P wave dispersion (P d = Pmax - Pmin). Results: There was a significant increase in Pmax at the end of dialysis compared to the beginning (98 ± 13 ms vs. 125 ± 12 ms, P < 0.001). P min did not show any significant change (71 ± 11 ms vs. 73 ± 10 ms, P = 0.42). Pd was significantly increased at the end of dialysis (27 ± 9 ms vs. 52 ± 11 ms, P < 0.001). There was a negative correlation between serum potassium, magnesium, phosphate, blood urea nitrogen, and creatinin at the end of dialysis and Pmax and P d respectively (P < 0.05). A weak positive correlation was found between serum calcium, bicarbonate at the end of dialysis and Pmax and Pd (P < 0.05). Conclusion: Hemodialysis ends with significant increase in P wave maximum duration and P wave dispersion, which might be responsible for the increased occurrence of atrial fibrillation in these groups of patients.
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    Mortality risk factors among critically ill children with MIS-C in PICUs: a multicenter study
    (Springer Nature, 2023) Sık G.; Inamlık A.; Akçay N.; Kesici S.; Aygun F.; Kendırlı T.; Atay G.; Sandal O.; Varol F.; Ozkaya P.Y.; Duyu M.; Bırbılen A.Z.; Ozcan S.; Arslan G.; Kangın M.; Bayraktar S.; Altug U.; Anıl A.B.; Havan M.; Yetımakman A.F.; Dalkıran T.; Zengın N.; Oto A.; Kıhtır H.S.; Gırgın F.İ.; Telhan L.; Yıldızdas D.; Yener N.; Yukselmıs U.; Alakaya M.; Kılınc M.A.; Celegen M.; Dursun A.; Battal F.; Sarı F.; Ozkale M.; Topal S.; Kocaoglu C.; Yazar A.; Alacakır N.; Odek C.; Yaman A.; Cıtak A.; Bıngol I.; Annayev A.; Sevketoglu E.; Katlan B.; Durak C.; Gun E.; Erdogan S.; Seven P.; Sahın E.; Arı H.F.; Boyraz M.; Durak F.; Emeksız S.; Ozdemır G.; Duman M.; Talay M.N.; Yener G.O.; Luleyap D.; Harmanogulları S.; Başar E.Z.; Mercan M.; Bal A.; Kılıc N.; Ongun E.A.; Ozturk M.N.; Ekıncı F.; Udurgucu M.; Arslankoylu A.E.; Kutlu N.O.; Bukulmez A.; Özsoylu S.; Celık T.; Ozkale Y.; Kılıc A.O.
    Background: This study evaluated of clinical characteristics, outcomes, and mortality risk factors of a severe multisystem inflammatory syndrome in children admitted to a the pediatric intensive care unit. Methods: A retrospective multicenter cohort study was conducted between March 2020 and April 2021 at 41 PICUs in Turkey. The study population comprised 322 children diagnosed with multisystem inflammatory syndrome. Results: The organ systems most commonly involved were the cardiovascular and hematological systems. Intravenous immunoglobulin was used in 294 (91.3%) patients and corticosteroids in 266 (82.6%). Seventy-five (23.3%) children received therapeutic plasma exchange treatment. Patients with a longer duration of the PICU stay had more frequent respiratory, hematological, or renal involvement, and also had higher D-dimer, CK-MB, and procalcitonin levels. A total of 16 patients died, with mortality higher in patients with renal, respiratory, or neurological involvement, with severe cardiac impairment or shock. The non-surviving group also had higher leukocyte counts, lactate and ferritin levels, and a need for mechanical ventilation. Conclusions: In cases of MIS-C, high levels of D-dimer and CK-MB are associated with a longer duration of PICU stay. Non-survival correlates with elevated leukocyte counts and lactate and ferritin levels. We were unable to show any positive effect of therapeutic plasma exchange therapy on mortality. Impact: MIS-C is a life-threatening condition.Patients need to be followed up in the intensive care unit.Early detection of factors associated with mortality can improve outcomes.Determining the factors associated with mortality and length of stay will help clinicians in patient management.High D-dimer and CK-MB levels were associated with longer PICU stay, and higher leukocyte counts, ferritin and lactate levels, and mechanical ventilation were associated with mortality in MIS-C patients.We were unable to show any positive effect of therapeutic plasma exchange therapy on mortality. © 2023, The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc.