Browsing by Author "Ozan E."
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Item No pituitary gland volume change in medication-free depressed patients(2008) Eker C.; Ovali G.Y.; Ozan E.; Eker O.D.; Kitis O.; Coburn K.; Gonul A.S.Increased serum cortisol levels and a hyperactive hypothalamo-pituitary-adrenal (HPA) axis have been proposed to play an important role in the pathophysiology of Major Depressive Disorder (MDD). However, there are inconsistent results regarding pituitary gland volume (PGV), which is one of the key elements of the HPA axis evaluated by MRI in depressed patients. In this study, we analyzed the PGV of medication-free moderately depressed MDD patients (N = 34) and age and sex matched healthy controls (N = 39). PGV did not differ between MDD patients and healthy controls [mean volume ± S.D.; 0.76 ± 0.17 cm3 and 0.75 ± 0.14 cm3; ANCOVA, F1,69 = 1.25 p > 0.05; respectively]. Our results confirm that volumetric PGV changes are not crucial for depression pathophysiology among unmedicated, moderately depressed adults. © 2008 Elsevier Inc. All rights reserved.Item Correlation of serum BDNF levels with hippocampal volumes in first episode, medication-free depressed patients(2010) Eker C.; Kitis O.; Taneli F.; Eker O.D.; Ozan E.; Yucel K.; Coburn K.; Gonul A.S.The hippocampus seems to be affected in MDD, and brain-derived neurotrophic factor (BDNF) has positive effects on neurogenesis within the hippocampus. Although there are inconsistencies among study results, a smaller hippocampal volume in depressed patients is thought to be related to the pathophysiology of the disease. We looked at the correlation between serum BDNF (sBDNF) levels and hippocampal volumes (HCV) of first-episode MDD patients (18 female, 7 male; mean age = 32.1 ± 9.3) and healthy controls (17 female, 5 male; mean age = 29.7 ± 6.4). Region of interest analysis was conducted on the images acquired via MRI. sBDNF levels and HCV correlated only in the MDD group (right: r = 0.46, P = 0.02; left: r = 0.47, P = 0.02); however, HCV did not differ between MDD patients and healthy controls (right: F = 2.45, df = 1.46, P > 0.05; left: F = 0.05, df = 1.46, P > 0.05). BDNF may be a factor underlying HCV differences between MDD and healthy control subjects, which become apparent as severe and multiple episodes are experienced. © 2010 Springer-Verlag.Item The impact of physical and psychological comorbid conditions on the quality of life of patients with acute myocardial infarction: A multi-center, cross-sectional observational study from Turkey(2013) Sertoz O.; Aydemir O.; Gulpek D.; Elbi H.; Ozenli Y.; Yilmaz A.; Ozan E.; Atesci F.; Abay E.; Semiz M.; Direk N.; Hocaoglu C.; Elyas Z.; Ozmen M.; Ozen S.; Konuk N.Objective: Acute myocardial infarction (MI) has significant and detrimental effects on the lifestyles of the patients. It has been shown that quality of life (QoL) in patients with MI is impaired in every aspect. This study aims to evaluate the impact of depression and physical comorbidity on QoL in Turkish patients with acute first MI. Method: This multi-center cross-sectional study was carried out in 15 centers with 998 patients hospitalized for acute first MI. For detection of depression, Beck Depression Inventory (BDI) was used. For evaluation of QoL, World Health Organization Quality of Life Questionnaire (WHOQOL) was applied. Results: The mean age of the patients was 57.5 ± 10.1 years and 79.2 % (n = 792) of the patients were men. Patients with comorbid depression (BDI ≥ 10) and comorbid medical conditions, and female patients had significantly lower scores in every domain of WHOQOL. In the regression analysis model, female gender, low education, comorbid medical conditions, especially comorbid hypertension, and BDI score were found to have a significant effect on the domains of WHOQOL. Conclusions: Female patients are more prone to impairment in quality of life after myocardial infarction. Both comorbid medical conditions and depression have a significant impact on the impairment of QoL in Turkish patients with acute MI. In order to improve the subjective wellbeing of post MI patients, both psychiatric and physical comorbidities must be detected and managed even in the short term. © 2013, Baywood Publishing Co., Inc.Item Challenges in diagnosing and adequately treating malignant catatonia and its fatal consequences(American Psychiatric Publishing Inc., 2014) Ozan E.; Aydin E.F.[No abstract available]Item Effect of anxiety and pain on success of shockwave lithotripsy (SWL) for treatment of proximal ureteral and renal pelvic stones(Springer Verlag, 2016) Ucer O.; Ceylan Y.; Ekren F.; Ozan E.; Muezzinoglu T.The aim of this study is to evaluate the impact of anxiety and pain on success of shockwave lithotripsy (SWL) for treatment of proximal ureteral and renal pelvic stones smaller than 15 mm. One hundred thirty-two patients with proximal ureteral or renal pelvic stones <15 mm who were treated by a SWL and forty controls were enrolled in the study. State-trait anxiety inventory (STAI) was used to assess anxiety of the controls and patients (before every SWL session). Pains of the patients were measured by a visual analog scale (VAS) at three times (T) of the sessions (T11 at 11 kV, T15 at 15 kV and T end of treatment). The mean STAI scores of the patients at the first SWL session and controls were 40.61 ± 8.71 and 36.11 ± 8.18, respectively (p < 0.05). There was statistically positive moderate relationship between STAI and VAS scores at the first SWL session. The mean size of stone in men and women were 11.16 ± 2.88 and 11.00 ± 3.41, respectively (p = 0.88). In the first session, the mean STAI and VAS scores of the men were significantly lower than the women. The stone-free rate (SFR) of SWL was 72.7 % in this study. The SFR of SWL in the men and women were 78 and 64 %, respectively (p < 0.05). Our data showed that the severity of anxiety and pain in the women were higher than the men. SFR of SWL in the men was higher than the women. The severity of anxiety and pain in the patients may affect SFR of SWL. © 2016, Springer-Verlag Berlin Heidelberg.Item Traumatic growth and psychological resilience status of female victims of violence inpatients in a district psychiatric hospital(W.B. Saunders, 2018) Arabaci L.B.; Dikec G.; Buyukbayram A.; Uzunoglu G.; Ozan E.The aim of this study was to examine the traumatic mental growth and psychological resilience status of females who were receiving inpatient treatment at a district mental health hospital and had a history of being subjected to violence. One hundred-twenty female patients with a history of exposure to violence participated in the study. An introductory information form, the Traumatic Growth Inventory (TGI) and the Psychological Resilience Scale for Adults (PRSA) were used for data collection. This study found that all the participants were subjected to emotional violence, 65.8% to physical violence, 30.8% to sexual violence, and 94.2% to verbal violence at some point in their lives. Their TGI mean score (60.96 ± 11.91) was above average, while their PRSA mean score (97.90 ± 9.18) was below average. The participants’ mean scores on the TGI and PRSA did not vary significantly by the type of violence (p > 0.05) to which the women were exposed. Moreover, no statistically significant relationship was found between the TGI and the PRSA total scale and subscale mean scores (p > 0.05). This study found that the posttraumatic growth of females who had a history of physical or emotional or sexual abuse was positive, and that their psychological resilience levels were inadequate. © 2018 Elsevier Inc.Item A clinical and sociodemographic evaluation of youths with substance use disorders in a child and adolescent inpatient unit of mental health hospital; [Bir bölge ruh sağlığı hastanesi çocuk ve ergen yataklı servisinde madde kullanımı nedeniyle yatarak tedavi gören gençlerin klinik ve sosyodemografik özellikleri](ANP Publishing, 2019) Bilaç Ö.; Kavurma C.; Önder A.; Doğan Y.; Uzunoğlu G.; Ozan E.Objective: The aim of this study was to evaluate the demographic and clinical data of substance users who were intreatment in Mental Health Hospital Child and Adolescent Psychiatry Inpatient Department. Method: Medical records of substance user patients treated between 2014 and 2017 in Inpatient Child Psychiatry Unit of Mental Health Hospital were examined retrospectively. SPSS 20.00 Statistical Package Program was used for statistical analysis. Results: Ninety-two substance user child and youth had been treated. The median age of cases was 15,4 (SD±1,4), the onset age of substance use was 13,1 (SD±1,4). 68,5% of these case is male gender and 31,5% is female. The most common substance used is marijuana and extacy (62%), the substance user youth have met with the substance around friends (90,2%). Living conditions were found to be lower socioeconomic level (50%). Discussion: According to our clinic results, substance use is an important problem affecting youths, especially at lower socioeconomic level and male adolescents. Our study represents only the clinical sample, so there is a need for more community-based epidemiological studies. © 2019 ANP Publishing. All rights reserved.Item Factors that predict the perception of spirituality and spiritual care of nurses working in high-risk units and the effect of death anxiety(Blackwell Publishing Inc., 2021) Rahman S.; Elbi H.; Cakmakci Cetinkaya A.; Altan S.; Ozan E.; Pirincci E.Purpose: Spirituality contributes to the health and well-being of individuals. This study investigates the factors that predict the spirituality perceptions and the effect of death anxiety of nurses. Design and Methods: This was a cross-sectional study, 382 nurses working in four public hospitals intensive care and emergency departments setting in two different cities in Turkey. Findings: Variables predicting the total and subscale scores of the Spirituality and Spiritual Care Rating Scale of nurses were determined by linear multiple regression analysis. Except for the religiousness subscale, the satisfaction level of nurses was found to be a significant predictor in total of Spirituality and Spiritual Care Scale. Practice Implications: Nurses working in high-risk units are unclear about their perception of spirituality and spiritual care. © 2020 Wiley Periodicals LLCItem Validity and reliability of the internalized stigma of Mental Illness Scale–Adolescent Form(John Wiley and Sons Inc, 2021) Dikeç G.; Bilaç Ö.; Uzunoğlu G.; Ozan E.Purpose: The goal of this study was to assess the validity and reliability of the Turkish version of the Internalized Stigma of Mental Illness Scale–Adolescent Form (ISMI-AF). Methods: A total of 145 adolescents (12–18 years of age) who were diagnosed with at least one mental disorder according to DSM-5-TR participated in the study. Data were collected at a mental health hospital between October 2017 and 2019 using a sociodemographic information form, the ISMI-AF, and Beliefs towards Mental Illness (BMI) Scale. Reliability (Cronbach's alpha, Split–Half, Spearman–Brown, Hotelling T2 test) and validity analyses of the ISMI-AF were performed. SPSS 26.0 and LISREL 8.80 software were used for statistical analyses. Results: The Cronbach's alpha coefficient for total score was.88, Split–Half score was.84, and the Spearman–Brown factor score was.85. Confirmatory factor analysis showed that the scale confirmed to the five-factor structure in adolescents, but factor loadings and reliability coefficients were low in the “stigma resistance” subscale. There was a positive and weak correlation between ISMI-AF and BMI (r =.37, p =.00). Conclusion: The ISMI-AF is a valid and reliable measurement tool that can be used in adolescents. This scale can help psychiatric nurses who work in this field identify and address internalized stigma, which is one of the key factors affecting adherence to treatment, especially in adolescents. © 2020 Wiley Periodicals LLCItem HOW AWARE ARE FAMILY PHYSICIANS OF THE SOCIAL LIFE AND LONELINESS OF OLDER PEOPLE?(Geriatrics Society, 2022) Üstündağ Ö.; Elbi H.; Ozan E.; Özcan F.Introduction: The consequences of social isolation and loneliness on health and well-being in old age are increasingly being acknowledged. In this study, we examined how older patients perceive their social relationships and loneliness and explored family physicians’ awareness of these issues. Materials and Methods: This descriptive study evaluated social relations and the loneliness of older patients using the UCLA loneliness scale (UCLA-LS), the Nottingham Health Profile Social Isolation (NHP-SI) subscale, and a social relations questionnaire. The responses of these patients to loneliness and being socially active were compared with the reactions of family physicians to the same topics. Results: Five family physicians and 200 older patients participated in this study. According to the patients’ education levels and economic status, both scales exhibited significant differences. A significant correlation was found between chronic disease and UCLA loneliness on the scale, while a significant difference was found in the social isolation subscale according to those who lived with. Moreover, the family physicians clearly understood the relationship between living alone and their economic status. Conclusion: This study revealed that the social isolation of older patients was affected by their education level, economic status, and who they lived with. It was also found that loneliness was affected by education level, financial situation, chronic disease, and disability. © 2022, Geriatrics Society. All rights reserved.Item In Their Own Voices; Living with Hidradenitis Suppurativa: A Qualitative Study(Lippincott Williams and Wilkins, 2023) Durgu N.; Ozan E.; Gencoglan G.OBJECTIVE: To provide a deeper assessment of the lived experience of patients with hidradenitis suppurativa, a chronic inflammatory disorder characterized by recurrent abscess, sinuses, and scars. METHODS This study used a phenomenologic approach. Researchers recruited 10 participants via purposive sampling. Data were collected via semistructured, in-depth, face-to-face interviews, and interpretative phenomenologic analysis was performed. RESULTS Data analysis uncovered two primary themes among participants' interview responses: "unending symptoms"and "life becoming hard."CONCLUSIONS The symptoms of hidradenitis suppurativa negatively affect individuals' family, professional, and daily lives, and patients may benefit from psychiatric intervention. © Wolters Kluwer Health, Inc. All rights reserved.Item Being a health care professional in the ICU serving patients with covid-19: A qualitative study(Elsevier Inc., 2023) Ozan E.; Durgu N.Background: The COVID-19 pandemic has placed a great deal of strain on healthcare providers across the world. There has been no research into the experiences of health care providers in Turkey caring for hospitalized patients with COVID-19 in the ICU. Objectives: To explain the experiences of health care providers who provide services to patients with Covid-19 in an intensive care unit. Methods: This study used a phenomenological approach to recruit 15 participants (10 nurses and 5 physicians). The data was gathered through semi-structured in-depth interviews conducted face-to-face. Results: The four primary themes that came up in the results were COVID-19: the unidentified enemy, front-line struggle, psychological struggle, and invasion of social life. Conclusion: During the epidemic, health care providers encountered several psychological, physical, social, and professional difficulties. All health care personnel must receive information and skills training on what to do in crisis and risk circumstances such as infectious disease, decision-making, anxiety management, and problem-solving during pandemics. © 2022 Elsevier Inc.