Browsing by Author "Ozbalci D."

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    Aplastic anemia, mucormycosis and aspergillosis in infectious mononucleosis: Success is possible
    (2007) Ergene U.; Ozbalci D.; Baykal B.; Metin Ciris I.; Yariktas M.
    Infectious mononucleosis (IM) is a rare cause of aplastic anemia in adults. We report of a patient in whom aplastic anemia, mucormycosis and aspergillosis complicated during the course of IM and successfully treated with liposomal amphotericin B. According to our searches in literature, we could not find a similar patient complicated and successfully treated like ours. © 2007 Elsevier Ltd. All rights reserved.
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    A patient with both hairy cell leukemia and subacute thyroiditis
    (2007) Ergene U.; Ozbalci D.; Akin H.
    Background: Hairy cell leukemia (HCL) presents with pancytopenia, splenomegaly, and monocyte-like hairy cells with eccentric nucleus in blood smear and bone marrow. Cladribine, pentostatin and interferon alpha are used for therapy. Fever is usually associated with infections of bacterial or viral origin. High mortality and morbidity are associated with bacterial infections in those who are untreated. Case Report: We report a 38 years old male HCL patient representing with fever and pain on the neck. The diagnosis of febrile neutropenia and subacute thyroiditis were made. For the therapy of subacute thyroiditis, paracetamol and propranolol were given. The patient had refused to take chemotherapy, so, when the thyroid function test reached the normal ranges, splenectomy was performed with the support of erythrocytes and platelet aphaeresis. At the follow up, the patient was in good state of health. Conclusions: Subacute thyroiditis should be kept in mind especially in HCL representing with fever and pain over the thyroid. According to our search on medical database, this is the first reported case of HCL with subacute thyroiditis in literature.
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    Brucellosis: A rare cause of febrile neutropenia in acute myeloblastic leukemia
    (2011) Ozbalci D.; Ergene U.; Cetin C.B.
    Brucellosis is a zoonotic disease and endemically seen in the Middle East, Eastern Europe and continental America. Febrile neutropenia related to Brucellosis has been reported only in a few cases. Brucella was cultured from the bone morrow of a 42-year-old woman who was admitted to hospital with symptoms of fever and fatigue and later diagnosed as acute myeloblastic leukemia (AML). The patient was treated for both AML and Brucellosis without any problems and discharged from the hospital after scheduling her follow-up visits. Brucellosis might be considered in the etiology of febrile neutropenia in endemic regions and must be treated effectively to prevent possible morbidity and mortality during or after chemotherapy. © 2010 Springer Science+Business Media, LLC.
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    H1N1 as a causative agent in febrile neutropenia of an acute myeloid leukaemia (AML) patient
    (2012) Ergene U.; Ozbalci D.; Tunger O.
    [No abstract available]
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    Successful management of imatinib despite alopecia and nail necrosis
    (2013) Ergene U.; Ozbalci D.
    Imatinib mesylate selectively inhibits bcr/abl and other non-specific tyrosine kinases, such as c-kit and platelet derived growth factor (PDGF) receptor and successfully used to treat chronic myeloid leukaemia (CML). In most cases, the drug is well tolerated: however, side effects can be seen. Hair loss and paronychia inflammation were often reported with Imatinib, but total alopecia was rarely mentioned. We report a CML patient who was presented with alopecia and paronychia inflammation probably induced by imatinib therapy. We have successfully treated our patient by cessation and then re-applying therapy with lower doses after improvement of lesions and have not found a similar report in literature. © 2013 Elsevier Ltd.