Browsing by Author "Rodrigues, J"

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    Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study
    Sousa-Pinto, B; Louis, G; Rodrigues, J; Giuliano, AFM; Baiardini, I; Braido, F; Czarlewski, W; Bedbrook, A; Haahtela, T; Valiulis, A; Brussino, L; Cecchi, L; Cruz, AA; Gemicioglu, B; Fokkens, WJ; Ivancevich, JC; Klimek, L; Kraxner, H; Kuna, P; Kupczyk, M; Kvedariene, V; Larenas-Linnemann, D; Louis, R; Nadif, R; Niedoszytko, M; Okamoto, Y; Ollert, M; Papadopoulos, NG; Patella, V; Pawankar, R; Pham-Thi, N; Pfaar, O; Regateiro, FS; Roche, N; Rouadi, PW; Samolinski, B; Sastre, J; Savouré, M; Scichilone, N; Sheikh, A; Taborda-Barata, L; Toppila-Salmi, S; Yorgancioglu, A; Zidarn, M; Anto, JM; Zuberbier, T; Canonica, GW; Ventura, MT; Fonseca, JA; Pétré, B; Bousquet, J
    BACKGROUND: EQ-5D-5L (EuroQOL, 5 Domains, 5 Levels) is a widely used health-related quality-of-life instrument, comprising 5 domains. However, it is not known how each domain is impacted by rhinitis or asthma control. OBJECTIVE: To assess the association between rhinitis or asthma control and the different EQ-5D-5L domains using data from the MASK-air mHealth app. METHODS: In this cross-sectional study, we assessed data from all MASK-air users (2015-2021; 24 countries). For the levels of each EQ-5D-5L domain, we assessed rhinitis and asthma visual analog scales (VASs) and the combined symptom-medication score (CSMS). We built ordinal multivariable models assessing the adjusted association between VAS/CSMS values and the levels of each EQ-5D-5L domain. Finally, we compared EQ-5D-5L data from users with rhinitis and self-reported asthma with data from users with rhinitis alone. RESULTS: We assessed 5354 days from 3092 users. We observed an association between worse control of rhinitis or asthma (higher VASs and CSMS) and worse EQ-5D-5L levels. In multivariable models, all VASs and the CSMS were associated with higher levels of pain/discomfort and daily activities. For anxiety/depression, the association was mostly observed for rhinitis-related tools (VAS nose, VAS global, and CSMS), although the presence of self-reported asthma was also associated with worse anxiety/depression. Worse mobility (walking around) was particularly associated with VAS asthma and with the presence of asthma.CONCLUSIONS: A worse rhinitis control and a worse asthma control are associated with higher EQ-5D-5L levels, particularly regarding pain/discomfort and activity impairment. Worse rhinitis control is associated with worse anxiety/depression, and poor asthma control with worse mobility. (c) 2023 American Academy of Allergy, Asthma & Immunology (J Allergy Clin Immunol Pract 2023;11:3742-51)