Browsing by Author "Sözen S."

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    A survey of patient preparation and technique of ultrasound-guided prostate biopsy: A multicenter study og urooncological association; [Ultrasonografi kιlavuzluǧunda yapιlan prostat biyopsisinde hasta hazιrlιǧι ve teknik anketi: Üroonkoloji derneǧi çcok merkezli çalιşmasι]
    (Turk Uroloji Dernegi, 2007) Bozlu M.; Akduman B.; Mungan U.; Özen H.; Baltaci S.; Türkeri L.; Kirkali Z.; Akdaş A.; Adsan Ö.; Akdoǧan B.; Altinel M.; Ataus S.; Ayan S.; Bilen C.Y.; Çal Ç.; Çek M.; Dündar M.; Işeri C.; Koşan M.; Lekili M.; Müezzinoǧlu T.; Özer G.; Özgök Y.; Perk H.; Soyupak B.; Soyupek S.; Soylu A.; Sözen S.; Şengör F.; Tansuǧ Z.; Tekin A.; Yildirim A.
    Introduction: Ultrasound-guided prostate biopsy is the standard method for the diagnosis of prostate cancer. The aim of the present survey is to assess the variability in patient preparation and technique of ultrasound-guided prostate biopsy among Turkish Urologists. Materials and Methods: In July 2004, a questionnaire was sent out to e-mail addresses of the members of Urooncological Association, asking about the details of prostate biopsy protocol of the members. The survey consisted of multiple choice questions about the patient preparation and prostate biopsy technique. Responses were acquired via e-mail and analyzed in detail. Results: Thirty two urologists from 24 centers responded. The biopsy procedure was performed by the urologist only in 54.16% of the centers, both urologist and radiologist in 37.5%, and radiologist only in 8.33%. Transrectal route was the most common method for ultrasound-guided prostate biopsy. A half of the responders performed biopsy when PSA was greater than 4 ng/ml. All of the centers administered antibiotic and a half of them used enema before the procedure. Approximately 37% of responders did not administer any type of analgesia, but 29.1% of all responders administered a periprostatic nerve block for reducing pain during the procedure. Most urologists obtained 10 or 12 biopsy cores and only 20.8% of them obtained routine transitional zone biopsy during the initial biopsy session. Conclusion: This survey demonstrated that patient preparation and technique of ultrasound-guided prostate biopsy is not standardized among Turkish Urologists, and a guideline on prostate biopsy is needed.
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    Adjuvant Treatment Approaches after Radical Prostatectomy with Lymph Node Involvement
    (Asian Pacific Organization for Cancer Prevention, 2022) Tavukçu H.H.; Erbatu O.; Akdoğan B.; İzol V.; Yücetaş U.; Sözen S.; Aslan G.; Şahin B.; Tinay İ.; Müezzinoğlu T.; Sumer
    Objective: The aim of this study was to evaluate the adjuvant treatment preferences and effects on disease progression in patients with pathologically positive lymph node prostate cancer. Methods: Patients who underwent radical prostatectomy from the prostate cancer database of the Turkish Urooncology Association with lymph node involvement were included in the study. Database includes prostate cancer patients from many experience Urooncology centers of Turkey. Adjuvant treatment approaches and the factors that effect the PSA recurrrence was analysed. Results: Postoperative median 2 (1-3) lymph nodes were found to be positive, and the median lymph node density was reported as 0.13 (0.07-0.25). Seventy-four percent of patients received adjuvant treatment postoperatively. Seventy four of the patients (46.54%) received hormonal therapy in combination with radiotherapy; 47 of them (29.55%) received only hormonal treatment and 20(12.57%) only received radiotherapy. The number of lymph nodes removed was less in the group requiring adjuvant treatment, and this group had a higher rate of surgical margin positivity and seminal vesicle invasion. In addition, adjuvant treatment group had a statistically significant higher lymph node density. There was no significant difference in Kaplan-Meier method comparing 5-year PSA recurrence-free survival in patients with and without adjuvant therapy. When the patient clustered as non-adjuvant, only hormonal therapy and hormonal therapy with radiotherapy, a significant survival advantage was found in the hormonal therapy with radiotherapy group compared to the other two groups (p=0.043). Conclusion: No significant difference was found between two groups in terms of time until PSA recurrence during our follow-up. In subgroup analysis survival advantage was found in the hormonal therapy with radiotherapy group compared to non-adjuvant and only hormonal therapy groups. © This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License.