Browsing by Author "Sapmaz S.Y."

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    Evaluation of child psychiatry consultations of stayed patients at pediatric clinic; [Pediatri Kliniǧinde Yatarak Tedavi Gören Hastalarda, Çocuk Psikiyatrisi Konsültasyonlarinin Deǧerlendirilmesi]
    (ANP Publishing, 2017) Özkan O.G.; Sapmaz S.Y.; Kandemir H.
    Object: This study was conducted to evaluate child psychiatry consultations of patients which were stayed in different clinics in a university hospital. Methods: The records of the patients who were consulted in between 01.07.2016 and 31.12.2016 and was made diagnosis according to DSM5 was scanned restrospectively. The sociodemographic information of the patients, the diagnosis of physical illness, the clinic requested for consultation, the reason for the consultation, the psychiatric diagnoses determined in the consultation result and the psychiatric treatment process were analyzed by using the SPSS 15.0 program. Results: Psychiatric consultation was requested for 55 inpatient children within a sixmonth period. %63,6 of consulted cases was a girl, %36,4 of them was a boy and the average age was found as 13,2 ± 3,6. When the consultations were evaluated, it was determined that the 23,6% of the patients were consulted for suicide attempt and 83,6% of them had at least one mental disorder. The most common diagnosis was major depression in the rate of 36,4% and psychotropic treatment was recommended to 38,2% of evaluated cases because of the psychiatric disorder. Discussion: In our study, it was found that the consultation rates were low despite the rate of psychopathology (83,4%) was rather high in consulated children and adolescents. This suggests that the doctors who are working in non-psychiatric areas are having difficulty understanding and evaluating the psychiatric symptoms in children and that the cooperation among physicians should be increased so that psychiatric illnesses can be better recognized. © 2017 ANP Publishing. All rights reserved.
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    Paliperidone metabolic effects in children and adolescents: A case report
    (ANP Publishing, 2017) Kefal M.I.; Kandemir H.; Sapmaz S.Y.; Öztürk M.; Özkan Y.; Özkan O.G.
    The use of atypical antipsychotics in children and adolescents has increased in recent years. A 16-year-old male patient reported that he had used paliperidone for 3 years and had gained weight during this period. Various laboratory tests were performed when the patient started treatment in our clinic. It is evident from the test result that 3-year use of paliperidone dramatically increased fasting blood sugar, total cholesterol, low-density lipoprotein, triglycerides and prolactin levels in the patient. The metabolic parameters of the patient decreased into the normal range once the medication was stopped. Thus, paliperidone should be used carefully based on the side effects for patients under 18 years of age. © 2017 ANP Publishing. All rights reserved.
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    Validity and reliability of the Turkish version of the DSM-5 "Severity Measure for Agoraphobia-Child Age 11-17"
    (Yerkure Tanitim ve Yayincilik, 2017) Sapmaz S.Y.; Erkuran H.O.; Ergin D.; Ozturk M.; Celasin N.S.; Karaarslan D.; Koroglu E.; Aydemir O.
    Objective: This study aimed to assess the validity and reliability of the Turkish version of the DSM-5 "Severity Measure for Agoraphobia-Child Age 11-17". Method: Study group consisted of 36 patients, who have been treated in a child psychiatry unit and diagnosed with agoraphobia, and 100 healthy volunteers who have been secondary and highschool students. For the assessment, the Screen for Childhood Anxiety and Related Emotional Disorders (SCARED) was used along with the DSM-5 "Severity Measure for Agoraphobia-Child Age 11-17". Results: Regarding reliability analyses, Cronbach's alpha internal consistency coefficient was calculated as 0.929. Test-retest correlation coefficient was 0.566. For concurrent validity, the measure showed a high correlation with the SCARED. In ROC analysis, area under ROC curve was calculated as 0.934. Conclusion: It was concluded that Turkish version of the DSM-5 "Severity Measure for Agoraphobia-Child Age 11-17" could be used as a valid and reliable tool both in clinical practice and for research purposes.
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    Validity and reliability of the Turkish version of DSM-5 "Severity of Acute Stress Symptoms-Child Age 11-17" Form
    (Yerkure Tanitim ve Yayincilik, 2017) Sapmaz S.Y.; Erkuran H.O.; Ergin D.; Celasin N.S.; Karaarslan D.; Ozturk M.; Koroglu E.; Aydemir O.
    Objective: This study aimed to assess the validity and reliability of the Turkish version of DSM-5 "Severity of Acute Stress Symptoms-Child Age 11-17" Form. Method: The scale was prepared by carrying out the translation and back- translation of DSM-5 "Severity of Acute Stress Symptoms-Child Age 11-17" Form. Study group consisted of 30 patients that have been treated in a child psychiatry clinic and diagnosed with posttraumatic stress disorder and 40 healthy volunteers that attended middle or high school at the study period. For the assessment, Child Posttraumatic Stress Reaction Index was also used along with DSM-5 "Severity of Acute Stress Symptoms-Child Age 11-17" Form Results: Regarding reliability analyses, Cronbach alpha coefficient for internal consistency was calculated as 0.918 while item- total score correlation coefficients ranged 0.595-0.837. Test-retest correlation coefficient was calculated as r=0.651. Concerning construct validity, one factor that could explain 67.7% of the variance was obtained. With respect to concurrent validity, the scale showed a high correlation with Child Posttraumatic Stress Reaction Index. Conclusion: It was concluded that Turkish version of DSM-5 "Severity of Acute Stress Symptoms-Child Age 11-17" Form could be used as a valid and reliable tool both in clinical practice and for research purposes.
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    Clinical findings, child and mother psychosocial status in functional constipation
    (Turkish Society of Gastroenterology, 2017) Appak Y.C.; Sapmaz S.Y.; Doǧan G.; Herdem A.; Özyurt B.C.; Kasirga E.
    Background/Aims: Functional constipation (FC) is a common problem in childhood. In this study, we aimed to analyze the clinical and sociodemographic findings of patients with FC, parenting behaviors, and psychosocial states of children and parents. Materials and Methods: According to the Roma III diagnosis criteria, 32 patients with FC and 31 healthy controls were included. Patients' clinical and sociodemographic data set associated with constipation was determined. Strengths and Difficulties Questionnaire was used to screen the emotional and behavioral problems in children. To evaluate the parents and family, Beck Depression Inventory, State-Trait Anxiety Inventory, Parental Attitude Research Instrument were used. Results: Emotional and peer problems subscale scores, parental concerns as well as over-parenting attitude were found higher in patients. Significant difference was also observed between the groups in terms of mean score of authoritarian attitude dimensions. Attitude of hostility and rejection and marital discordance was found to be significantly high in patient families. Our study revealed a decrease in the constipation rate with the increasing education level of parents, higher rate of constipation in families with less income than expenses, and lower rate of working mothers in patients with constipation. Parents' depressive symptoms and anxiety level were determined to be considerably higher. Conclusion: A mother's low education level, low socioeconomic level, presence of psychological symptoms, and problems of parental attitude-primarily the authoritarian attitude-increase the risk of FC occurrence. Therefore, FC patients and their families should definitely undergo a psychosocial assessment. ©Copyright 2017 by The Turkish Society of Gastroenterology.
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    Prevalence of Childhood Affective disorders in Turkey: An epidemiological study
    (Elsevier B.V., 2018) Karacetin G.; Arman A.R.; Fis N.P.; Demirci E.; Ozmen S.; Hesapcioglu S.T.; Oztop D.; Tufan A.E.; Tural U.; Aktepe E.; Aksu H.; Ardic U.A.; Basgul S.; Bilac O.; Coskun M.; Celik G.G.; Demirkaya S.K.; Dursun O.B.; Durukan I.; Fidan T.; Gencoglan S.; Gokcen C.; Gokten E.S.; Gorker I.; Gormez V.; Gundogdu O.Y.; Gurkan C.K.; Herguner S.; Kandemir H.; Kilic B.G.; Kilincaslan A.; Mutluer T.; Nasiroglu S.; Ozcan O.O.; Ozturk M.; Sapmaz S.Y.; Suren S.; Sahin N.; Tahiroglu A.Y.; Toros F.; Unal F.; Vural P.; Yazici I.P.; Yazici K.U.; Yildirim V.; Yulaf Y.; Yuce M.; Yuksel T.; Akdemir D.; Altun H.; Ayik B.; Bilgic A.; Bozkurt O.H.; Cakir E.D.; Ceri V.; Demir N.U.; Dinc G.; Irmak M.Y.; Karaman D.; Kinik M.F.; Mazlum B.; Memik N.C.; Ozdemir D.F.; Sinir H.; Tasdelen B.I.; Taskin B.; Ugur C.; Uran P.; Uysal T.; Uneri O.S.; Yilmaz S.; Yilmaz S.S.; Acikel B.; Aktas H.; Alaca R.; Alic B.G.; Almbaidheen M.; Ari F.P.; Aslan C.; Atabay E.; Ay M.G.; Aydemir H.; Ayranci G.; Babadagi Z.; Bayar H.; Bayhan P.C.; Bayram O.; Bektas N.D.; Berberoglu K.K.; Bostan R.; Cakan Y.; Canli M.A.; Cansiz M.A.; Ceylan C.; Coskun N.; Coskun S.; Demir I.; Demir N.; Demirdogen E.Y.; Dogan B.; Donmez Y.E.; Donder F.; Efe A.; Eray S.; Erbilgin S.; Erden S.; Ersoy E.G.; Eseroglu T.; Firat S.K.; Gok E.E.; Goksoy S.C.; Guler G.; Gules Z.; Gunay G.; Gunes S.; Gunes A.; Guven G.; Horozcu H.; Irmak A.; Isik U.; Kahraman O.; Kalayci B.M.; Karaaslan U.; Karadag M.; Kilic H.T.; Kilicaslan F.; Kinay D.; Koc E.B.; Kocael O.; Mutlu R.K.; San Z.; Nalbant K.; Okumus N.; Ozbek F.; Ozdemir F.A.; Ozdemir H.; Ozgur B.G.; Ozkan S.; Ozyurt E.Y.; Polat B.; Polat H.; Sekmen E.; Sertcelik M.; Sevgen F.H.; Sevince O.; Shamkhalova U.; Suleyman F.; Simsek N.E.; Tanir Y.; Tekden M.; Temtek S.; Topal M.; Topal Z.; Turk T.; Ucar H.N.; Ucar F.; Uygun D.; Uzun N.; Vatansever Z.; Yazgili N.G.; Yildiz D.M.; Yildiz N.; Ercan E.S.
    Aim: To determine the prevalence of affective disorders in Turkey among a representative sample of Turkish population. Methods: This study was conducted as a part of the “The Epidemiology of Childhood Psychopathology in Turkey” (EPICPAT-T) Study, which was designed by the Turkish Association of Child and Adolescent Mental Health. The inclusion criterion was being a student between the second and fourth grades in the schools assigned as study centers. The assessment tools used were the K-SADS-PL, and a sociodemographic form that was designed by the authors. Impairment was assessed via a 3 point-Likert type scale independently rated by a parent and a teacher. Results: A total of 5842 participants were included in the analyses. The prevalence of affective disorders was 2.5 % without considering impairment and 1.6 % when impairment was taken into account. In our sample, the diagnosis of bipolar disorder was lacking, thus depressive disorders constituted all the cases. Among depressive disorders with impairment, major depressive disorder (MDD) (prevalence of 1.06%) was the most common, followed by dysthymia (prevalence of 0.2%), adjustment disorder with depressive features (prevalence of 0.17%), and depressive disorder-NOS (prevalence of 0.14%). There were no statistically significant gender differences for depression. Maternal psychopathology and paternal physical illness were predictors of affective disorders with pervasive impairment. Conclusion: MDD was the most common depressive disorder among Turkish children in this nationwide epidemiological study. This highlights the severe nature of depression and the importance of early interventions. Populations with maternal psychopathology and paternal physical illness may be the most appropriate targets for interventions to prevent and treat depression in children and adolescents. © 2018
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    Validity and reliability of the Turkish version of the severity measure for specific phobia - child form according to DSM-5
    (Yerkure Tanitim ve Yayincilik, 2018) Sapmaz S.Y.; Erkuran H.O.; Ergin D.; Ozturk M.; Celasin N.S.; Karaarslan D.; Koroglu E.; Aydemir O.
    Objective: This study aimed to assess the validity and reliability of the Turkish version of the Severity Measure for Specific Phobia - Child Form according to DSM-5. Method: The study group consisted of 50 patients treated in a child psychiatry unit and diagnosed with any specific phobia and 100 healthy volunteers. For the assessment, the Screen for Childhood Anxiety and Related Emotional Disorders (SCARED) was used along with the Severity Measure for Specific Phobia - Child Form according to DSM-5. Results: For reliability, Cronbach's alpha internal consistency coefficient was calculated to be 0.961. Test-retest correlation coefficient was calculated r=0.750. As for construct validity, one factor that could explain 74.1% of the variance was obtained, which is consistent with the original structure of the scale. As for concurrent validity, the correlation coefficient with the SCARED in children is r=0.480. Conclusion: It was concluded that the Turkish version of the DSM-5 Severity Measure for Specific Phobia - Child Form can be utilized as a valid and reliable tool both in clinical practice and for research purposes. © 2018 Dusunen Adam. All rights reserved.
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    Hypertension induced by aripiprazole use in an autistic child patient
    (Korean College of Neuropsychopharmacology, 2019) Uzun A.D.; Sapmaz S.Y.; Öztürk M.; Kandemir H.
    Atypical antipsychotics in children and adolescents are widely used for aggression, emotional variability and psychosis treatment. Aripiprazole is also an atypical antipsychotic that increasingly used in children and adolescents with schizophrenia, autism and bipolar disorder. In this case report, a medically healthy patient with autism associated with behavioral problems is presented with the development of hypertension after the onset of aripiprazole and the return of blood pressure to normal levels after withdrawal of the drug. The purpose of this case study is to discuss and report the emergence of aripiprazole-induced hypertension as a side effect of drugs in children and adolescents. © 2019, Korean College of Neuropsychopharmacology.
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    Aripiprazole Elevated the Thyroid-Stimulating Hormone Level and is Associated With Hyperprolactinemia
    (Lippincott Williams and Wilkins, 2020) Öztürk M.; Sapmaz S.Y.; Özkan Y.; Kandemir H.
    [No abstract available]
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    Tardive Oculogyric Crisis Due to Aripiprazole Treatment in an Adolescent Patient Diagnosed with Bipolar Disorder
    (AVES, 2020) Canol T.; Sapmaz S.Y.; Uzun A.D.; Kandemir H.
    Antipsychotics usage in children and adolescents is becoming widespread. One of the extrapyramidal side effects associated with long-term antipsychotic drug use follow-up is an oculogyric crisis (OGC). OGC is defined as a dystonic reaction commonly observed after typical antipsychotic drug administration. However, there are rare cases which report OGC after atypical antipsychotic use. In this report, we present an adolescent with bipolar disorder who developed OGC after 2 years of aripiprazole and quetiapine use. To best of our knowledge, this case report has been the first case to present the clinical presentation of tardive OGC due to aripiprazole treatment in an adolescent patient. It is important to note that OGC might be observed in the acute phase and it might be as a result of chronic use detected during a clinical follow-up. Safety, tolerability and efficiency of aripiprazole in pediatric populations should be further analyzed in the future studies. © 2020, AVES. All rights reserved.
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    Behavioral characteristics of children with type-1 diabetes and the effect of family attitudes on dietary adherence problems
    (Kare Publishing, 2021) Onen O.; Nalbantoglu O.; Erkuran H.O.; Sapmaz S.Y.; Erbas M.; Arslan G.; Ozkan B.
    Objective: Assessing the behavioral characteristics and family attitudes of children and adolescents in diabetes is linked to determining the reasons for difficulties in dietary adherence. Our aim was to assess the relationship between behavioral characteristics, family attitudes in children diagnosed with type 1 diabetes mellitus (T1DM), and the dietary adherence and glycemic control. Method: Fifty-four patients T1DM patients and 47 controls aged 7-18 years were included in the study together with their parents. Among the patients diagnosed with T1DM followed in the Pediatric Endocrinology Outpatient Clinic, those with high HbA1c levels (with poor dietary compliance) and those with a HbA1c level below 7.5 (with good dietary compliance) were included in the study as the patient and control group, respectively. A psychiatric assessment interview was conducted with both groups. Sociodemographic data and information on diabetes-related variables, Strengths and Difficulties Questionnaire and Parental Attitude Scale scores were recorded. Results: We have found higher standard diet application rates in patients compared to regular carbohydrate count. The patient group had higher odds of neglecting blood glucose measurement, insulin doses, and a history of stress before decompensation. The rate of psychiatric diagnosis was 26.2%, similar to the general literature, and combined diagnoses were less frequent. Hospital admissions and hypoglycemic episodes were observed at a higher rate in the group that had problems in dietary adherence. Compared to those with good dietary compliance, patients in the dietary non-adherence group had a higher level of parental control and poorer parental perception of their children’s peer relationships. Conclusion: To reduce the risk of acute complications of the disease and to prevent long-term chronic sequelae, it is important to identify positive and some negative behavioral characteristics of child and parental attitudes. Parental role is among the key factors in supporting the autonomy of the child in ensuring dietary compliance. © 2021 Yerkure Tanitim ve Yayincilik Hizmetleri A.S.. All rights reserved.
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    Clinical and psychosocial factors affecting treatment adherence in children with rheumatic heart disease
    (NLM (Medline), 2022) Alkan F.; Yigit E.; Sapmaz S.Y.; Coskun S.
    INTRODUCTION: The present study aimed to investigate the outcomes of psychiatric symptoms and family functions on treatment adherence in children, in addition to sociodemographic characteristics and clinical factors related to the disease. MATERIAL AND METHOD: The research sample consisted of 43 children who were followed up with rheumatic heart disease diagnosis during the study. Clinical features were obtained from the patient files. The family assessment device evaluating family functioning and the strengths and difficulties questionnaire scale to screen emotional and behavioural problems in children were used. RESULTS: Considering the regularity of treatment in our patients, there were 31 (72%) patients adherent to secondary prophylaxis regularly, 7 (6.9%) patients were partially adherent, and 5 (11.6%) patients non-adherent. Patients were divided into treatment adherent (Group 1) and non-adherent (Group 2). There was no statistically significant impact on treatment adherence whether the patients receive enough information, lifestyle, fear of developing adverse effects, fear of addiction, lack of health insurance, difficulties in reaching the drug or hospital. However, the fear of syringes on treatment adherence had an effect statistically significantly (p = 0.047). Forgetting to get a prescription and/or take the drug when the time comes was statistically higher in the non-adherent group (p = 0.009). There was no statistically significant effect of psychosocial factors on treatment adherence between groups. DISCUSSION: Providing an effective active recall system, involving primary care workers, providing training on the disease and its management, and a comprehensive pain management programme can improve the process, especially for cases where secondary prophylaxis is missed.
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    Reliability and Validity of the Bipolar Prodrome Symptom Interview and Scale-Full Prospective in Its Turkish Translation
    (Mary Ann Liebert Inc., 2022) Sapmaz S.Y.; Ermiş Ç.; Çaklr B.; Öztekin S.; Guinart D.; Alşen Güney S.; Correll C.U.; Inal N.; Aydemir Ö.
    Editors' Note: The Editors would like to address issues related to the acceptance of this manuscript. The original manuscript referenced the study tool as the Bipolar Prodrome Symptom Interview Scale-Prospective (BPSS-P). After the manuscript's initial acceptance, the authors requested a revision of the tool name to Bipolar Prodrome Symptom Interview Scale-Full Perspective (BPSS-FP). When this request was made, the original acceptance was rescinded, and the authors were asked to formally revise and resubmit the manuscript with an explanation for the change. This revision and subsequent review led to the final acceptance of the manuscript. The authors have assured us that the tool used in the manuscript was the BPSS-FP (version 5) as opposed to abbreviated forms of this tool that are also used in research (e.g., Bipolar Prodrome Symptom Scale-Abbreviated Screen for Patients (BPSS-AS-P). Background: No scale exists to assess patients at-risk for bipolar disorder (BD) in Turkey. We aimed to assess the psychometric properties of the Turkish version of the Bipolar Prodrome Symptom Interview and Scale-Full Prospective (BPSS-FP). Method: Psychiatric service users aged 11-18 years old were interviewed using the BPSS-FP translated into Turkish and the Kiddie Schedule for Affective Disorders and Schizophrenia. Youth with major depressive disorder (MDD, n = 63), bipolar-spectrum disorder (n = 47), and healthy controls (n = 122) were included. Cronbach's alpha was calculated to assess internal consistency. The Young Mania Rating Scale (YMRS) and Children's Depression Rating Scale-Revised (CDRS-R) were administered to test convergent/discriminant validity. Discriminant validity was further tested using one-way ANOVA and "receiver operating characteristic"(ROC) curves. Inter-rater reliability was tested using correlation coefficients. Findings: Across 232 youth, Cronbach's alpha values were 0.932 for the BPSS-FP total score, 0.878 for the Mania Symptom Index, 0.887 for the Depression Symptom Index, and 0.797 for the General Symptom Index. Correlation coefficients for inter-rater reliability were high for the Mania Symptom Index (r = 0.989), Depression Symptom Index (r = 0.973), and General Symptom Index (r = 0.981). There were high correlations between the BPSS-FP Mania Symptom Index subscore and YMRS (r = 0.732), and the BPSS-FP Depression Symptom Index subscore and CDRS-R (r = 0.754), whereas cross-polarity correlations were non-significant. ROC analysis cut-off value was ≥21 for the BPSS-FP Mania Symptom Index between patients with BD and MDD (specificity = 85.7%, sensitivity = 78.7%). Conclusion: The Turkish version of the BPSS-FP has good psychometric properties and can be used in research. Longitudinal studies are needed to confirm the predictive value of the BPSS-FP. © Copyright 2022, Mary Ann Liebert, Inc., publishers 2022.
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    Nonsuicidal self-injury in adolescents: Role of sociodemographic and clinical factors, emotion regulation, and maladaptive personality traits
    (Kare Publishing, 2022) Canol T.; Sapmaz S.Y.; Barut E.A.; Cakir A.D.U.; Bilac O.; Kandemir H.
    Objective: This study aims to assess the individual and psychosocial factors related to nonsuicidal self-injury (NSSI). Method: This study included patients with NSSI (n=44), non-NSSI patients (n=37), and a healthy control group (n=38) between 12 and 18 years of age. The clinical interviews were conducted with all participants. The participants completed an information form, the Difficulties in Emotion Regulation Scale (DERS), and the Personality Inventory for DSM-5-Brief Form. Results: In our findings, NSSI was associated with difficulties in peer relationships, disruption in family unity, domestic violence, smoking, sexual abuse, physical abuse, and suicidal ideation history. Patients in the NSSI group showed higher scores on the DERS than those in other groups. They also showed a higher level of maladaptive personality traits compared with adolescents in other groups. Our findings showed that NSSI was associated with suicidal ideation history and maladaptive personality traits. Conclusion: The existing literature and our findings indicate that previous suicidal ideation and maladaptive personality traits might be suggestive of NSSI. Considering these potential risk factors would allow clinicians to develop more suitable early intervention, follow-up, and treatment strategies for NSSI in the adolescent population. © 2022 Yerkure Tanitim ve Yayincilik Hizmetleri A.S.. All rights reserved.
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    Index depressive episode and antidepressant exposure were associated with illness characteristics of pediatric bipolar disorder
    (John Wiley and Sons Inc, 2022) Inal N.; Ermis C.; Koc D.; Aksoy S.; Karacetin G.; Tuncturk M.; Eray S.; Karabina B.; Faruk Akca O.; Ozgul D.; Gunay Kilic B.; Cikili Uytun M.; Besenek M.; Kavurma C.; Bilac O.; Gokcen C.; Topal Z.; Percinel Yazıcı I.; Sapmaz S.Y.; Ozyurt G.; Diler R.S.
    Objective: Pediatric bipolar disorder (PBD) is a serious, recurrent disorder leading to severe functional impairment. As a first mood episode, index episode could affect the long-term course of the illness. This study aimed to investigate the clinical characteristics of youth with PBD from our multicenter, nationwide, naturalistic follow-up samples and to identify (i) the effects of index mood episode and (ii) the effect of previous antidepressant treatments on the age at mania onset of PBD. Method: The study sample consisted of 271 youth with BD-I followed by the child and adolescent psychiatry clinics of seven different university hospitals and three research state hospitals, representing six geographic regions across Turkey. All diagnoses were made according to structured interviews, and all data were retrospectively obtained from clinical records by the clinicians. Results: When patients with index depressive/mixed episodes (IDE, n=129) and patients with index (hypo)manic episodes (IME, n=142) were compared, the total number of mood episodes and rapid cycling feature were significantly higher in the IDE group than in the IME group. The Cox regression analysis adjusted for sociodemographic and illness characteristics revealed female adolescents in the IDE group treated with antidepressants were more likely to have an earlier onset of mania (hazard ratio=2.03, 95% confidence interval=1.31–3.12, p=0.001). Conclusion: This is the first large-scale nationwide follow-up study in Turkey that indicated prior antidepressant treatments were associated with an earlier onset of mania in youth, particularly in adolescent females. Larger prospective studies are needed to identify neurodevelopmental processes underlying PBD and initiate prevention approaches. © 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
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    Prevalence, comorbidities and mediators of childhood anxiety disorders in urban Turkey: a national representative epidemiological study
    (Springer Science and Business Media Deutschland GmbH, 2023) Mutluer T.; Gorker I.; Akdemir D.; Ozdemir D.F.; Ozel O.O.; Vural P.; Tufan A.E.; Karacetin G.; Arman A.R.; Fis N.P.; Demirci E.; Ozmen S.; Hesapcioglu S.T.; Oztop D.; Tural U.; Aktepe E.; Aksu H.; Ardic U.A.; Basgul S.; Bilac O.; Coskun M.; Celik G.G.; Demirkaya S.K.; Dursun O.B.; Durukan I.; Fidan T.; Gokcen C.; Gormez V.; Gundogdu O.Y.; Herguner S.; Kandemir H.; Kilic B.G.; Kilincaslan A.; Nasiroglu S.; Sapmaz S.Y.; Sahin N.; Tahiroglu A.Y.; Toros F.; Unal F.; Yazici I.P.; Yazici K.U.; Isik U.; Ercan E.S.
    Purpose: The aim of this study is to evaluate the prevalence of anxiety disorders, its correlation with sociodemographic characteristics, its comorbidities with other psychiatric disorders and its predictors in school-aged children. Methods: This study is part of a representative, multi-centered national study that is planned by the Turkish Association of Child and Adolescent Mental Health to evaluate the prevalence of psychopathology among elementary school students in Turkey between the years 2014–2015. Children are screened via Kiddie Schedule for Affective Disorders and Schizophrenia for School Age Children Present and Lifetime Version. Impairment is assessed by a 3-point Likert type scale independently by the parent and the teacher. The final sample included 5842 children with the mean age of 8.7 years. Results: The prevalence of any anxiety disorder without considering impairment is 16.7% and considering impairment is 5.2% in children according to our study. We found significant differences for comorbid Attention Deficit Hyperactivity Disorder, Disruptive Behavior Disorder, Mood Disorders, Tic Disorders, Obsessive Compulsive Disorder, Enuresis Nocturna, Encopresis, and Intellectual Disability. Having a history of paternal physical disorder, living in the regions of Marmara, Mediterranean and Black Sea were found to be the main predictors of having childhood anxiety disorders according to the logistic regression analysis. Conclusion: Better understanding of childhood anxiety disorders, comorbid conditions and predictors will result in earlier diagnosis and more appropriate treatment. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.
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    Should pediatric cardiologists refer all patients with unexplained chest pain to a psychiatrist?
    (Cambridge University Press, 2023) Alkan F.; Sapmaz S.Y.; Kardelen C.; Bircan O.; Bilac O.; Kandemir H.; Coskun S.
    Objective: The present study aimed to investigate the relationship between unexplained chest pain in children with parents' mental problems, parental attitudes, family functionality, and the child's mental problems. Material and Method: A total of 433 children (between 11 and 18 years of age) applied to the Pediatric Cardiology Outpatient Clinic due to chest pain in the last year. A clinical interview was conducted by a child psychiatrist with 43 patients and 33 controls included in the study due to unexplained chest pain. Results: Family history of physical illness was significantly higher in the chest pain group. When evaluated in terms of psychosocial risk factors, life events causing difficulties, derangement in the family, loss of a close person, and exposure to violence were statistically significantly higher in the group with chest pain. Mental disorders were observed in 67.4% of the children in the chest pain group as a result of the clinical interview. The total score of the DSM-5 somatic symptoms scale, which evaluates other somatic complaints in the chest pain group, was also significantly higher. When the family functions of both groups were evaluated, communication, emotional response, behaviour control, and general functions sub-dimensions were statistically significantly higher in families in the chest pain group. Conclusion: We recommend that psychiatric evaluation be included in diagnostic research to prevent unnecessary medical diagnostic procedures in children describing unexplained chest pain, as well as to prevent the potential for diagnosing mental disorders in both children and adults. © The Author(s), 2024. Published by Cambridge University Press.