Browsing by Author "Sari S."
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Item A pre- and postoperative evaluation of multiple joint involvement as the initial finding of cervical syringomyelia and neuropathic arthropathy; [Servikal siringomiyelin ve nöropatik artropatinin ilk bulgusu olarak ortaya çi{dotless}kan çoklu eklem tutulumunun ameliyat öncesi ve sonrasi{dotless} deǧerlendirilmesi](2013) Kisabay A.; Zeybek S.; Sari S.; Tanyeli A.; Selçuki D.Syringomyelia is a progressive, degenerative disorder, in which a longitudinal cyst forms within the spinal cord. Neuropathic arthropathy can be seen in the late phases of the disease, with the most frequent involvement being in the shoulder. Herein, we present a 42-year-old female case who was diagnosed with syringomyelia as well as Arnold-Chiari Syndrome and neuropathic arthropathy. Her initial complaints were painless edema in the right shoulder and elbow, wounds on the tips of her fingers and amputations. She was evaluated both pre- and postoperative periods. It should be kept in mind that neuropathic arthropathy may develop as the initial symptom in spinal cord lesions which progress slowly. ©2013 Turkish League Against Rheumatism. All rights reserved.Item Knowledge Level of the Primary Healthcare Providers on Chronic Obstructive Pulmonary Disease and Pulmonary Rehabilitation(Hindawi Publishing Corporation, 2015) Goktalay T.; Tuncal A.N.; Sari S.; Koroʇlu G.; Havlucu Y.; Yorgancioʇlu A.Awareness of the healthcare providers on chronic obstructive pulmonary disease (COPD), which is an important cause of mortality and morbidity in our country and all over the world, and on pulmonary rehabilitation (PR) which plays an important role in its nonpharmacological treatment will provide effectiveness in diagnosis and treatment of COPD. The present study aimed at determining knowledge level of the healthcare providers about COPD and PR. Materials and Methods. In this cross-sectional study, family practitioners and staff of home-care in central county of Manisa City were applied a questionnaire in order to determine their knowledge level on COPD and pulmonary rehabilitation during the in-service training on "pulmonary rehabilitation, home-care services for the pulmonary diseases, and respiratory exercises." Results. 65.5% of the healthcare providers responded to the survey. Rate of those correctly knowing at least one of four items was 97.2%. No responder knew all items correctly. Average value for correct answers was 5.30 ± 2.1 (range: 1-10). The physicians, men, and those working in family health centers had higher level of knowledge on COPD compared to nonphysician healthcare providers (p = 0.006), women (p = 0.002), and those working in other practices (p = 0.019), respectively. Conclusion. Knowledge level of the primary healthcare providers on COPD and PR remains inadequate. Dynamic postgraduate training on this topic will be useful in referring the patients to centers giving service for this condition. © 2015 Tuʇba Goktalay et al.Item Manifestation of hashimoto's encephalopathy with psychotic signs: A case presentation(Yerkure Tanitim ve Yayincilik, 2016) Kisabay A.; Balikci K.; Sari S.; Selcuki D.Hashimoto's encephalopathy (HE) is a rare autoimmune disease with unclear pathophysiology, developing on the basis of Hashimoto's thyroiditis (HT), associated with antithyroid antibodies, that presents with autoimmune, neuroendocrine, and neuropsychiatric findings. The disease is characterized by generalized or focal slowing in the EEG, elevated antithyroid antibody titration in the serum, elevated cerebrospinal fluid protein level, and the presence of antithyroid antibodies. HE is known as an autoimmune disorder of the central nervous system. With this feature, it is differentiated from cognitive alterations observed in hypothyroidism or hyperthyroidism. The response to treatment with corticosteroids in line with the autoimmune nature of HE supports this diagnosis. This report shows a case presenting with neuropsychiatric symptoms, elevated antithyroid antibody titration in the serum, and complete response to steroid therapy. A clear indicator for the diagnosis of HE has not yet been found. Therefore, other potential causes need to be considered in the differential diagnosis of this clinical picture until they can be excluded after investigations. With this case report, we want to emphasize that in differential diagnosis of patients presenting with a variety of neuropsychiatric symptoms, Hashimoto's encephalopathy-though being seen quite rarely-should not be disregarded, given the dramatic improvement of patients receiving a correct diagnosis and appropriate treatment.Item Miller Fisher Syndrome/pharyngeal-cervical-brachial variant of GBS overlap and human herpes Virus-6 reinfection: May there BE a relationship?; [MFS/ Faringeal-Servikal-Brakial variant GBS Çakışması ile human herpes Virüs enfeksiyonu arasında bir ilişki var mı?](Ege University Press, 2016) Mavioğlu H.; Kisabay A.; Sari S.; Akçali S.; Oktan B.Miller Fisher Syndrome (MFS) is a rare variant of Gulliain Barre syndrome (GBS) characterized by external ophthalmoplegia, ataxia, areflexia, and usually by positive anti GQ1b antibody. It occurs through an autoimmune mechanism most frequently after Campylobacter jejuni, followed by Haemophilus influenzae infection. Although occurrence with other viruses and bacteria has been reported, the concurrence of MFS and Human Herpes Virus-6 (HHV-6) has not been reported so far. There are a few publications reporting association of GBS with HHV-6. In the present study, HHV-6 DNA with PCR was detected in the cerebrospinal fluid (CSF) of a 59 year-old female patient diagnosed with MFS/pharyngeal-cervical-brachial variant of GBS overlap from clinical findings and positive anti-GQ1b antibody in the serum. This article aims to create awareness of a possible relationship between MFS, GBS and HHV-6. © 2016, Ege University Press. All right reserved.Item The validity and reliability of the turkish version of the leicester cough questionnaire in COPD patients(Turkiye Klinikleri Journal of Medical Sciences, 2018) Kurhan F.; Göktalay T.; Havlucu Y.; Sari S.; Yorgancioğlu A.; Çelik P.; Şakar Coşkun A.Background/aim: The reliability and validity of the Turkish version of the Leicester Cough Questionnaire (LCQ) have been evaluated before. This study aimed to validate the Turkish version of the LCQ in chronic obstructive pulmonary disease (COPD) patients with cough. Materials and methods: COPD (GOLD B, C, D) patients over age 40 (n = 75) and healthy volunteers as a control group (n = 75) were included. A sociodemographic data form, the LCQ, the Short Form-36 (SF-36) quality of life questionnaire, and the World Health Organization Quality of Life Brief Form for Turkish people were completed. The internal reliability of the LCQ was determined using the Cronbach alpha coefficient (>0.6) and its repeatability by the intraclass consistency coefficient (P < 0.05) was accepted as significant. Results: For internal consistency, Cronbach alpha coefficients of all subscales of the LCQ, physical, psychological, and social, were found as 0.72, 0.86, and 0.83, respectively, with 0.92 for the total index. There was significant internal consistency for all subscales and the total index (Cronbach alpha coefficients of >0.6). In test–retest reliability, the correlation coefficient ranged between 0.71 and 0.80 for each question and was calculated as r = 0.89 for total LCQ score (P < 0.001). Conclusion: The Turkish version of the LCQ has been found to have acceptable reliability and validity for use in Turkish COPD patients with chronic cough. © TÜBİTAK.Item Familial mediterranean fever mutation analysis in pediatric patients with İnflammatory Bowel Disease: A multicenter study(AVES, 2021) Urganci N.; Ozgenc F.; Kuloǧlu Z.; Yüksekkaya H.; Sari S.; Erkan T.; Önal Z.; Çaltepe G.; Akçam M.; Arslan D.; Arslan N.; Artan R.; Aydoǧan A.; Balamtekin N.; Baran M.; Baysoy G.; Çakir M.; Dalgiç B.; Doǧan Y.; Durmaz O.; Ecevit C.; Eren M.; Gökçe S.; Gülerman F.; Gürakan F.; Hizli S.; Işik I.; Kalayci A.G.; Kansu A.; Kutlu T.; Karabiber H.; Kasirga E.; Kutluk G.; Hoşnut F.O.; Özen H.; Özkan T.; Öztürk Y.; Soylu O.B.; Tutar E.; Tümgör G.; Ünal F.; Ugraş M.; Üstündaǧ G.; Yaman A.Background: The aim of the study was to evaluate familial Mediterranean fever (FMF) mutation analysis in pediatric patients with inflammatory bowel disease (IBD). The relation between MEFV mutations and chronic inflammatory diseases has been reported previously. Methods: Children with IBD (334 ulcerative colitis (UC), 224 Crohn's disease (CD), 39 indeterminate colitis (IC)) were tested for FMF mutations in this multicenter study. The distribution of mutations according to disease type, histopathological findings, and disease activity indexes was determined. Results: A total of 597 children (mean age: 10.8 ± 4.6 years, M/F: 1.05) with IBD were included in the study. In this study, 41.9% of the patients had FMF mutations. E148Q was the most common mutation in UC and CD, and M694V in IC (30.5%, 34.5%, 47.1%, respectively). There was a significant difference in terms of endoscopic and histopathological findings according to mutation types (homozygous/ heterozygous) in patients with UC (P < .05). There was a statistically significant difference between colonoscopy findings in patients with or without mutations (P = .031, P = .045, respectively). The patients with UC who had mutations had lower Pediatric Ulcerative Colitis Activity Index (PUCAI) scores than the patients without mutations (P = .007). Conclusion: Although FMF mutations are unrelated to CD patients, but observed in UC patients with low PUCAI scores, it was established that mutations do not have a high impact on inflammatory response and clinical outcome of the disease. Copyright © 2021 by The Turkish Society of Gastroenterology.Item A view on pediatric airway management: a cross sectional survey study(Edizioni Minerva Medica, 2022) Saracoglu A.; Saracoglu K.T.; Sorbello M.; Kurdi R.; Greif R.; Abitagaoglu S.; Akin M.; Aksu A.; Aladag E.; Alagoz A.; Alanoglu Z.; Alicikus Tuncel Z.; Altinisik H.B.; Ambrosoli A.L.; Amella S.; Andrašovský A.; Andreotti A.; Arici A.G.; Armstrong J.; Arslan B.; Ávila E.; Aydogmus I.; Ayhan A.; Ayoglu H.; Ayvat P.; Bakis M.; Basaran B.; Baytar C.; Begec Z.; Belete A.; Belludi R.; Bianco M.C.; Bilgin M.U.; Biricik E.; Brueggeney M.K.; Bunjaku D.; Buyukkocak U.; Catineau J.; Cebrián C.G.; Chinnappa S.M.; Cicekci A.; Corte-Ballester J.; Cuéllar Martínez A.B.; Caglar T.; Calisir F.; Cokay Abut Y.; Delen L.A.; Deligoz O.; Demirgan S.; Distefano R.; Dmytriiev D.; Duarte L.; Ece C.; El-Tahan M.; El-Hatib M.; Erdogan Ari D.; Erkalp K.; Erol D.; Erturk E.; Frada R.; Fuchs A.; Garini E.; Gecici M.E.; Giallongo M.; Gomes C.; Gurbuz H.; Has Selmi N.; Hasani A.; Hernandez Cera C.; Hilker T.; Horatanaruang D.; Huitink J.; Karaaslan P.; Karaveli A.; Karisik M.; Kavas A.D.; Kaya A.; Kendigelen P.; Kilinc G.; Koc S.; Dilmen O.; Kozanhan B.; Kupeli I.; Kuyrukluyildiz U.; Lleshi A.; Loizou M.; Luanpholcharoenchai J.; Martinez V.; Matoshi D.; Maurya I.; Meco B.C.; Michalek P.; Milic M.; Mitre I.; Montealegre F.; Nair A.; Nallbani R.; Ng A.; Oc B.; Ok G.; Olguner C.; Ozkan D.; Oksuz G.; Ozcan M.S.; Ozden E.S.; Ozden Omaygenc D.; Ozer Y.; Ozmenoglu Turker H.; Ozmert S.; Rai E.; Rangappa D.; Roca De Togores A.; Salgado H.; Santos P.; Sari S.; Saritas A.; Saygi Emir N.; Sen B.; Shallik N.; Shamim F.; Shirgoska B.; Silay E.; Sinha T.; Srimueang T.; Sudarshan P.; Sugur T.; Sumer I.; Szucs Z.; Sahin T.; Sanal Bas S.; Tan J.; Tawfik L.; Topal S.; Toy E.; Turan Civraz A.Z.; Unal D.; Ural S.G.; Ustalar Ozgen S.Z.; Uysal H.; Yesildal H.; Yilmaz C.; Yuen V.; Yurt E.; Yuzkat N.; Zdravkovic M.; Isohanni M.BACKGROUND: This survey aimed to investigate routine practices and approaches of clinicians on pediatric airway in anesthesia and intensive care medicine. METHODS: A 20-question multiple-choice questionnaire with the possibility to provide open text answers was developed and sent. The survey was sent to the members of European Airway Management Society via a web-based platform. Responses were analyzed thematically. Only the answers from one representative of the pediatric service of each hospital was included into the analysis. RESULTS: Among the members, 143 physicians responded the survey, being anesthesiologists (83.2%), intensivists (11.9%), emergency medicine physicians (2.1%), and (2.8%) pain medicine practitioners. Astraight blade was preferred by 115 participants (80.4%) in newborns, whereas in infants 86 (60.1%) indicated a curved blade and 55 (38.5%) a straight blade. Uncuffed tracheal tube were preferred by 115 participants (80.4%) in newborns, whereas 24 (16.8%) used cuffed tubes. Approximately 2/3 of the participants (89, 62.2%) reported not to use routinely a cuff manometer in their clinical practice, whereas 54 participants (37.8%) use it routinely in pediatric patients. Direct laryngoscopy for routine pediatric tracheal intubation was reported by 127 participants (88.8%), while 16 (11.2%) reported using videolaryngoscopes routinely. Interestingly, 39 (27.3%) had never performed neither videolaryngoscopy nor flexible bronchoscopy in children. These results were significantly less in hospitals with a dedicated pediatric anesthesiologist. CONCLUSIONS: This survey on airway management in pediatric anesthesia revealed that the use of cuffed tubes and the routine monitoring of cuff pressure are rare. In addition, the rate of videolaryngoscopy or flexible optical intubation was low for expected difficult intubation. Our survey highlights the need for properly trained pediatric anesthesiologists working in-line with updated scientific evidence. © 2022 Edizioni Minerva Medica. All rights reserved.Item Functional parameters and affecting factors in post-COVID period; [Post-COVID dönemde fonksiyonel parametreler ve etkileyen faktörler](Ankara University, 2023) Kizilirmak D.; Fidan U.; Sari S.; Havlucu Y.Introduction: Post-COVID period is considered to be 12 weeks after the COVID-19 infection. Patients in the post-COVID period may have prolonged or newly developed symptoms. Depending on the prolonged effects of the disease, respiratory and functional parameters may be affected. The aim of the study is to investigate the effect of COVID-19 infection on respiratory and functional parameters in the post-COVID period. Materials and Methods: A cross-sectional study was conducted to evaluate the functional parameters of patients with COVID-19 in the post-COVID peri-od. Subjects with a history of microbiologically proven COVID-19 infection were evaluated with 6-minute walk test results, Borg, and MRC results at least 12 weeks after COVID-19 infection. The relationship between demographic characteristics, comorbidities, vaccination status, and severity of disease with 6-minute walk test results and dyspnea scales in the post-COVID period was investigated. Results: Two hundred seventeen patients were included in the study. The mean age of the patients was 48.6 ± 14.9 years and 126 (58.1%) of them were fema-le. 142 (65.4%) of the patients were completely vaccinated against COVID-19 and 75 (34.6%) patients were incompletely vaccinated or unvaccinated. 158 (72.8%) patients had mild disease, 51 (23.5%) patients had moderate disease, and eight (3.7%) patients had severe disease. Those with a history of moderate or severe disease had significantly worsened functional parameters in the post-COVID period compared to those with mild COVID-19. The Borg scale and MRC dyspnea scale values were significantly higher in women (p= 0.008, p= 0.002, respectively). Functional parameters of those who were completely vaccinated against COVID-19 and those who were incompletely or unvaccinated individuals in the post-COVID period were similar. Conclusion: The functional parameters of people with moderate or severe COVID-19 disease were found to be significantly impaired in the post-COVID period. While the effect of smoking and vaccination status on functional parameters in the post-COVID period could not be demonstrated, disease severity and accompanying comorbidity were found to be effective. © 2023 by Tuberculosis and Thorax.Item A comparison of the effects of thoracolumbar interfascial plane (TLIP) block and erector spinae plane (ESP) block in postoperative acute pain in spinal surgery(Springer Science and Business Media Deutschland GmbH, 2024) Dilsiz P.; Sari S.; Tan K.B.; Demircioğlu M.; Topçu İ.; Erel V.K.; Aydin O.N.; Turgut M.Purpose: Spinal surgeries are a very painful procedure. New regional techniques for postoperative pain management are being considered. The present study aimed to evaluate the hypothesis that the ultrasound-guided erector spinae plane (ESP) block would lead to lower opioid consumption compared to the thoracolumbar interfascial plane (TLIP) block after lumbar disk surgery. The study's primary objective was to compare postoperative total opioid consumption, and the secondary objective was to assess postoperative pain scores. Methods: Sixty-eight patients who underwent elective lumbar disk surgery were randomly assigned to either the ESP block group or the TLIP block group. The current pain status of the patients in both the ESP and TLIP block groups was assessed using the Numerical Rating Scale (NRS) at specific time intervals (30 min, 1, 6, 12 and 24 h) during the postoperative period. The number of times patients administered a bolus dose of patient-controlled analgesia, (PCA) within the first 24 h was recorded. Results: In the ESP group, the total opioid consumption in terms of morphine equivalents was found to be significantly lower (ESP group: 7.7 ± 7.0; TLIP group: 13.0 ± 10.1; p < 0.05). The NRS scores were similar between the groups at 30 min, 1, 6, and 12 h, but at 24 h, they were significantly lower in the ESP group. Moreover, the groups had no significant difference regarding observed side effects. Conclusion: This study demonstrated the analgesic efficacy of both techniques, revealing that the ESP block provides more effective analgesia in patients undergoing lumbar disk surgery. © The Author(s) 2024.Item Relationship between functional status and fatigue after COVID-19 infection: a multicenter study from Türkiye(TUBITAK, 2024) Candemir İ.; Ergün P.; Kaymaz D.; Şahin M.E.; Özmen İ.; Yildirim E.; Görek Dilektaşli A.; Yiğitliler B.; Odabaş A.; Kizilirmak D.; Sari S.; Korkmaz C.; Taşçi C.; Arslan Y.; Savci S.; Kahraman B.; Tanriverdi A.; Sevinç C.; Sağlam M.; İnal İnce D.; Vardar Yağli N.; Kütükçü E.; Durmaz D.; Durutürk N.; Ulubay G.; Kiliç L.; Çağlayan B.; Moray A.; Olcay S.S.; Özkaya G.Background/aim: Symptoms of COVID-19 may persist for months. One of the persistent symptoms of COVID-19 is fatigue, which reduces functional status. The relationship between fatigue, functional status, and various other factors has received little attention, which this study aims to address.. Materials and methods: Patients with COVID-19 infection were included in this multicenter cross-sectional study. Age, sex, body mass index (BMI), marital status, smoking status, presence and duration of chronic disease, comorbidity index, regular exercise habits, time since COVID-19 diagnosis, hospitalization status, length of hospital stay, intubation status, home oxygen therapy after discharge, participation in a pulmonary rehabilitation program, presence of dyspnea, presence of cough, presence of sputum, and modified Medical Research Council, Post-COVID Functional Status (PCFS), Fatigue Severity Scale (FSS), and EQ-5D-5L Questionnaire scores were recorded. Results: We enrolled 1095 patients, including 603 (55%) men and 492 (45%) women with a mean age of 50 ± 14 years. The most common chronic lung disease was COPD (11%) and 266 (29%) patients had nonpulmonary disease. The median time elapsed since COVID-19 diagnosis was 5 months; the hospitalization rate was 47%. The median PCFS grade was 1 (0–4) and the median FSS score was 4.4 (1–7). The PCFS and FSS were positively correlated (r = 0.49, p < 0.01; OR: 1.88, 95% CI: 1.68–2.10). Both functional status and fatigue were associated with quality of life, which was lower in older patients, those with higher BMI, those with systemic disease, those not exercising regularly, and those with more severe COVID-19 infection (defined by dyspnea, pneumonia as indicated by computed tomography, hospitalization, length of stay, ICU admission, intubation, and the need for home oxygen after discharge). Conclusion: Fatigue may cause poorer functional status regardless of the time since COVID-19 diagnosis. In this study, patients with FSS scores of >4.78 showed moderate to severe functional limitations. It is important to address modifiable patient risk factors and reduce the severity of COVID-19 infection. © 2024, TUBITAK. All rights reserved.