Browsing by Author "Savci, S"

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    Do mobility exercises in different environments have different effects in ankylosing spondylitis?
    Gurpinar, B; Ilcin, N; Savci, S; Akkoc, N
    Aims: Ankylosing spondylitis (AS) reduces spinal mobility, which results in structural and functional impairments. Pulmonary problems eventually occur in most AS patients due to interstitial lung disease or as a result of chest wall abnormalities. The aim of this study was to evaluate the effects on pulmonary functions and disease related scales of aquatic and land-based multidimensional functional mobility exercises on pulmonary functions in patients with AS. Methods: In this randomized controlled study, 57 patients with definite AS according to the modified New York criteria were randomly allocated to an aquatic (AG), land-based (LG), or home (HG) exercise group and performed multidimensional mobility exercise sessions twice a week for 8 weeks. The Bath indices were used to measure disease activity, functional limitation, and spinal mobility, and a 10-cm visual analog scale assessed pain during activity and at rest. Pulmonary function tests, maximal inspiratory mouth pressure (MIP), and maximal expiratory mouth pressure (MEP) were measured before and after the intervention. The study is registered at ClinicalTrials.gov, number NCT03667625 (27/08/2018). Results: Forty-six patients (30.4% female) with a mean age of 42.0 years completed the study. Multidimensional exercises improved disease-related symptoms such as pain, spinal mobility, and functionality, but there were no significant changes in HG. Patients in AG showed significant improvements in peak expiratory flow (p=0.004), vital capacity ( p=0.025), maximum voluntary ventilation (p=0.006), and MIP (p=0.001), while those in LG showed significant increases in forced expiratory volume during the first second to forced vital capacity (FEV1/FVC) ratio (p=0.049), peak expiratory flow (p=0.007), and maximum voluntary ventilation (p=0.004). There were no significant changes in HG. Conclusions: Multidimensional functional mobility exercises performed either in water or on land are important in the management of pulmonary manifestations of AS.
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    REMOVAL OF MALACHITE GREEN A CATIONIC DYE FROM WASTEWATER VIA ADSORPTION ON FISH BONES
    Savci, S; Kemiklioglu, E
    In this study, the removal of Malachite Green synthetic dye from aqueous environment was investigated using Sparus aurata as a source of fish bone. The removal efficiency of the adsorbent was investigated as a function of time and dye concentration via batch method at room temperature. The correlation coefficient values indicate that the data fit the Freundlich Isotherm (R-2= 0,9861) better than the Langmuir Isotherm (R-2=0,3695). The thermodynamic and reaction kinetic of Malachite Green from the aqueous solution were determined and correlated to pseudo-second order kinetic models and the experimental data revealed that pseudo-second order kinetic model is available to experimental data. Gibbs free energy value was found to be -1.308 kJ/mol and indicating the spontaneity of the system. Thermodynamic parameters exhibited that the adsorption process was spontenous (Delta G
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    Relationship between functional status and fatigue after COVID-19 infection: a multicenter study from Turkiye
    Candemir, I; Ergün, P; Kaymaz, D; Sahin, ME; Özmen, I; Yildirim, E; Dilektasli, AG; Yigitliler, B; Odabas, A; Kizilirmak, D; Sari, S; Korkmaz, C; Tasci, C; Arslan, Y; Savci, S; Kahraman, B; Tanriverdi, A; Sevinç, C; Saglam, M; Ince, DI; Yagli, NV; Kütükcü, E; Durmaz, D; Durutürk, N; Ulubay, G; Kiliç, L; Çaglayan, B; Moray, A; Olcay, SS; Özkaya, G
    Background/aim: Symptoms of COVID-19 may persist for months. One of the persistent symptoms of COVID-19 is fatigue, which reduces functional status. The relationship between fatigue, functional status, and various other factors has received little attention, which this study aims to address.. Materials and methods: Patients with COVID-19 infection were included in this multicenter cross-sectional study. Age, sex, body mass index (BMI), marital status, smoking status, presence and duration of chronic disease, comorbidity index, regular exercise habits, time since COVID-19 diagnosis, hospitalization status, length of hospital stay, intubation status, home oxygen therapy after discharge, participation in a pulmonary rehabilitation program, presence of dyspnea, presence of cough, presence of sputum, and modified Medical Research Council, Post-COVID Functional Status (PCFS), Fatigue Severity Scale (FSS), and EQ-5D-5L Questionnaire scores were recorded. Results: We enrolled 1095 patients, including 603 (55%) men and 492 (45%) women with a mean age of 50 +/- 14 years. The most common chronic lung disease was COPD (11%) and 266 (29%) patients had nonpulmonary disease. The median time elapsed since COVID-19 diagnosis was 5 months; the hospitalization rate was 47%. The median PCFS grade was 1 (0-4) and the median FSS score was 4.4 (1-7). The PCFS and FSS were positively correlated (r = 0.49, p < 0.01; OR: 1.88, 95% CI: 1.68-2.10). Both functional status and fatigue were associated with quality of life, which was lower in older patients, those with higher BMI, those with systemic disease, those not exercising regularly, and those with more severe COVID-19 infection (defined by dyspnea, pneumonia as indicated by computed tomography, hospitalization, length of stay, ICU admission, intubation, and the need for home oxygen after discharge). Conclusion: Fatigue may cause poorer functional status regardless of the time since COVID-19 diagnosis. In this study, patients with FSS scores of >4.78 showed moderate to severe functional limitations. It is important to address modifiable patient risk factors and reduce the severity of COVID-19 infection.
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    A multicenter randomized trial for the effectiveness of structured discharge and follow-up protocol on readmission rate in COPD patients receiving LTOT/NIV: one-year interim analysis.
    Ergan, B; Goktalay, T; Ergun, P; Yilmaz, D; Ocakli, B; Gurgun, A; Demirci, N; Elverisli, F; Ucar, EY; Durmaz, A; Dilektasli, AG; Aksoy, E; Elmas, F; Kokturk, N; Aytekin, F; Akgun, M; Ozyilmaz, E; Cetinoglu, ED; Tuncay, EA; Tasbakan, S; Balbay, O; Demir, AU; Ergun, R; Savci, S; Karakurt, Z; Ekinci, B; Gemicioglu, B; Yorgancioglu, A
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    The Relationship Between Functional Status and Fatigue After COVID-19 Infection
    Candemir, IÇ; Ergun, P; Kaymaz, D; Özmen,; Yildirim, E; Dilektasli, AG; Yigitler, B; Kizilirmak, D; Sari, S; Korkmaz, C; Tasçi, C; Arslan, Y; Savci, S; Kahraman, B; Tanriverdi, A; Sevinç, C; Saglam, M; Ince, DI; Yagli, NV; Kütükçü, E; Durmaz, D; Durutürk, N; Ulubay, G; Kiliç, L; Çaglar, B; Moray, A; Olcay, SS