Browsing by Author "Simsek H."

Now showing 1 - 4 of 4
  • No Thumbnail Available
    Item
    The effects of meloxicam on neural tube development in the early stage of chick embryos; [Meloksikamın erken dönem civciv embriyosunda nöral tüp geliflimine etkileri]
    (Turkish Neurosurgical Society, 2010) Cetinkal A.; Colak A.; Topuz K.; Demircan M.N.; Simsek H.; Berber U.; Umur A.S.; Selcuki M.; Vatansever H.S.
    AIM: The aim of this study is to demonstrate the effect of meloxicam in early stage chick embryos on neural tube development. MATERIAL and METHODS: One hundred specific pathogen-free (SPF) chicken eggs were used to investigate the neurulation. SPF eggs were invastigated in four groups (n:25). All of the groups were incubated at 37.2 ± 0.1°C and 60 ± 5 % relative humidity for 30 hours, and an embryological development in the ninth stage as classified by Hamburger and Hamilton was obtained. In the end of the 30th hour, group A(control group) was administered 0.1 ml of saline (0.9% NaCl) in ovo and the other groups were administered meloxicam in increasing doses. At the end of 72 hours, all of the embryos were extracted from eggs and they underwent pathological examination with hematoxylin eosine and immunohistopathological examinations with CD138 and tubulin beta II. RESULTS: While the groups Aand B showed no neural tube defects, totally eight defective embryos were detected in the groups C and D (three in group C and five in group D. CONCLUSION: Our results suggested that meloxicam, a nonselective COX inhibitor, caused neural tube closure defects when injected at supratherapeutic doses. However, further studies with larger numbers of subjects are needed for its use in lower doses.
  • No Thumbnail Available
    Item
    Decomposing socioeconomic inequalities in self assessed health in Turkey
    (2012) Sözmen K.; Baydur H.; Simsek H.; Ünal B.
    Introduction. This study aimed to measure socioeconomic inequalities in Self Assessed Health (SAH) and evaluate the determinants of such inequalities in terms of their contributions amongst the Turkish population. Methods. We used data from the Turkish part of World Health Survey 2003 with 10,287 respondents over 18 years old. Concentration index (CI) of SAH was calculated as a measure of socioeconomic inequalities in health, and contributions of each determinant to inequality were evaluated using a decomposition method. Results: In total 952 participants (9.3%) rated their health status as either bad or very bad. The CI for SAH was -0.15, suggesting that suboptimal SAH was reported more by those categorised as poor. The multiple logistic regression results indicated that having secondary, primary or less than primary school education, not being married and being in the lowest wealth quintile, significantly increased the risk of having poor SAH. The largest contributions to inequality were attributed to education level (70.7%), household economic status (9.7%) and geographical area lived in (8.4%). Conclusion: The findings indicate that socioeconomic inequalities measured by SAH are apparent amongst the Turkish population. Education and household wealth were the greatest contributing factors to SAH inequality. These inequalities need to be explicitly addressed and vulnerable subgroups should be targeted to reduce the socioeconomic disparities. © 2012 Sözmen et al.; licensee BioMed Central Ltd.
  • No Thumbnail Available
    Item
    Quality parameters of vineyard irrigation water in a semi-arid region: The Plain of Alasehir, Turkey
    (Parlar Scientific Publications, 2014) Yagmur B.; Aydin S.; Okur B.; Coban H.; Simsek H.
    Production of seedless raisins is extremely important in Aegean Region in Turkey. The Plain of Alasehir in province of Manisa in Aegean Region is extremely important for seedless raisin production since 25% of the seedless raisin has been grown in this area. The irrigation water samples were collected from 13 different water distribution locations in the Plain of Alasehir. Results showed that pH and EC (electrical conductivity) values were in a reasonable range except EC levels from two locations were slightly high. The vineyard irrigation water in the region was classified as type of C3S1. It was suggested that, the salt content might be monitored continuously since salinity might increase in the soil through the end of the irrigation season. The most common cations were Ca++ and Mg++, and anion was HCO3\ Trace elements and heavy metals were under the risk limits except Mn was high in three locations. Boron was high in nine sampling locations. Overall, irrigation waters in the Plain of Alasehir were suitable for vineyard irrigation as long as the contents of boron and salinity were continuously monitored. © by PSP.
  • No Thumbnail Available
    Item
    The nutritional conditions and some heavy metal contents of the vineyards in a semi-arid area
    (Parlar Scientific Publications, 2015) Aydin S.; Yagmur B.; Coban H.; Simsek H.
    Turkey is one of the most important seedless raisin producers in the world market. Approximately, 82% of the seedless raisin has been produced in the western part of Turkey since the climate (semi-arid) of this region is very appropriate to grow seedless grape. More specifically, the Plain of Alasehir, located in the Gediz Basin in Aegean Region has been known its high quality seedless raisin production. About 25% of the seedless raisin of the entire Aegean Region is produced in the Plain of Alasehir. Therefore, the Plain of Alasehir region was selected to determine some heavy metal contents (Cd, Co, Cr, and Pb) and certain macro and micro element contents (N, P, K, Ca, Mg, Fe, Zn, Mn, and Cu) of the leaf samples obtained from the vineyards in the area. The plant samples from 13 vineyards were analyzed by collecting the samples across the first plant bunch during the veraison period. In terms of nutrition profile, N deficiency was detected in 15% of vineyards while P deficiency was determined in 38.5 % of the vineyards. Similarly, Fe deficiency was detected in the 30.8 % of the vineyards. The contents of Zn, Mn, Cu, K, Ca, and Mg were sufficient in all of the vineyards. Some heavy metal contents of the leaf samples were analyzed and it was found that there was no pollution for the Cd, Co, and Pb in all the vineyards. Cr pollution was not detected in 93.2% of the samples.