Browsing by Author "Türel-Ermertcan, A"
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Item Inappropriate treatments at beauty centersTürel-Ermertcan, A; Sahin, MT; Yurtman, D; Kapulu, N; Öztürkcan, SItem Targetoid haemosiderotic haemangiomaSahin, MT; Demir, MA; Gunduz, K; Özturkcan, S; Türel-Ermertcan, ATargetoid haemosiderotic haemangioma represents a new, rarely reported, distinctive, benign vascular tumour, characterized histopathologically by a biphasic growth pattern of dilated vascular structures in the superficial dermis lined by prominent hobnail endothelial cells and collagen dissecting, rather narrow neoplastic vessels in deeper parts of the lesion. In the initial stage, the lesion is seen as a small purple or violaceous papule, 2-3 mm in diameter. Over time, the ecchymotic ring expands peripherally until it disappears spontaneously. In the later stages, however, the central papule remains as a slightly raised dermal lesion with a purple to brownish discolouration. We report three cases whose repetitive cyclic morphological changes of targetoid haemosiderotic haemangiomas were monitored dermoscopically at 3-month follow-ups. Histopathological examination of each lesion identified the features of targetoid haemosiderotic haemangioma. To the best of our knowledge, our three cases are the first reported in the literature of targetoid haemosiderotic haemangiomas that were regularly monitored by dermoscopic examinations, enabling development of the different stages of the same lesion to be followed.Item Behcet's disease associated with hidradenitis suppurativaSahin, MT; Öztürkcan, S; Türel-Ermertcan, A; Yurtman-Havlucu, D; Bilaç, CItem Generalized granuloma annulare in a patient with type II diabetes mellitusSahin, MT; Türel-Ermertcan, A; Öztürkcan, S; Türkdogan, PItem Trombosed solitary angiokeratoma of Mibelli simulating malignant melanomaSahin, MT; Türel-Ermertcan, A; Öztürkcan, S; Türkdogan, PItem Ectodermal dysplasia showing clinical overlap between AEC, Rapp-Hodgkin and CHAND syndromesSahin, MT; Türel-Ermertcan, A; Chan, I; McGrath, JA; Öztürkcan, SThe ectodermal dysplasias represent a complex collection of congenital abnormalities of skin, hair, teeth, nail, and sweat gland development, many of which have overlapping clinical features. In this report, we describe a 7-year-old girl, born to clinically normal parents, with ankyloblepharon, cleft lip/palate and hair abnormalities, features resembling the autosomal dominant disorder, ankyloblepharon-ectodermal dysplasia-clefting (AEC) syndrome, which results from mutations in the sterile-alpha motif domain of the gene encoding the transcription factor, p63. However, direct sequencing of the p63 gene in this individual did not reveal any pathogenic sequence variants. Moreover, two of her paternal cousins were discovered to have similar congenital ectodermal anomalies, raising the alternative possibility of an autosomal recessive pattern of inheritance. Furthermore, all affected individuals lacked a history of erosive scalp dermatitis that is usually characteristic of AEC syndrome. Instead, the scalp hair was coarse and wiry. In addition, another atypical feature, hypohidrosis, was present. Collectively, the clinical features also resembled Rapp-Hodgkin syndrome, Bowen-Armstrong syndrome and CHAND syndrome, but did not appear to fit neatly with any one particular disorder. This case highlights the difficulties in trying to classify the ectodermal dysplasia syndromes on clinical features alone.