Browsing by Author "Türkdoǧan P."

Now showing 1 - 11 of 11
  • No Thumbnail Available
    Item
    Histopathological evaluation of the urethra after the Snodgrass operation: An experimental study in rabbits
    (2002) Genç A.; Taneli C.; Günşar C.; Türkdoǧan P.; Yilmaz O.; Arslan O.A.; Mir E.
    Objective: To investigate the histopathological outcome of the incised urethral plate after tubularized incised-plate urethroplasty (the Snodgrass procedure to repair hypospadias) in a hypospadiac rabbit model, as it can produce meatal and neourethral strictures, and healing with scarring. Materials and methods: The study comprised 10 male New Zealand White rabbits (2.2-2.4 kg); under general anaesthesia the ventral urethra was completely excised 1 cm from the meatus proximally and a model of hypospadias formed. A full-thickness incision was then made in the distal dorsal urethra and the two sides of the incision marked by Indian ink tattooing. After placing a feeding tube (5 F) as a urethral catheter, both urethral wings were sutured ventrally by a 7/0 polydioxanone running suture, and the penile skin approximated by 5/0 chromic catgut. At 21 days and 3 months after surgery the penises were harvested. assessed histopathologically, and compared with those from control untreated rabbits of the same age and weight. Results: In the study group the incised area of the dorsal urethra was re-epithelialized; the regional tissue and vascularity were normal. Conclusion: In this rabbit model the dorsal urethral incisions healed with no scar tissue: only the ventral suture lines had minimal fibrosis and inflammatory reaction.
  • No Thumbnail Available
    Item
    A rare side-effect of systemic isotretinoin treatment: Pyogenic granuloma [6]
    (2003) Türel A.; Öztürkcan S.; Şahin M.T.; Türkdoǧan P.
    [No abstract available]
  • No Thumbnail Available
    Item
    Needle-Guided Shave Excision with Ultrasonographic Assistance: A New Technique
    (2003) Seyhan A.; Tarhan S.; Türkdoǧan P.
    BACKGROUND. A lack of control in the deep margin of shave excision is a drawback of this technique. OBJECTIVE. To describe a more precise shaving technique by sonography with the use of a fine injector needle as a depth marker. METHODS. After having examined the invasion levels of 40 benign skin lesions, a fine injector needle was intentionally threaded into the dermis horizontally just beneath the required shaving plane. Correct placement of the needle was ensured by sonographic examination after possible reinsertion trials. Large lesions needed several needles to be inserted. The tissue above the needles was then shaved off, whereas the deep dermal layer was protected. RESULTS. Histologic examination revealed that 77% of superficial and intermediate-thickness lesions were removed totally without disturbing the derma-fat junction. CONCLUSION. The needle-guided technique was found to be effective in the control of the deep margin of shave excision.
  • No Thumbnail Available
    Item
    Coexistence of basalioma, Bowen's disease and porokeratosis of Mibelli; [Ayni olguda bazalyoma, Bowen hastaliǧi ve porokeratozis Mibelli birlikteliǧi]
    (2003) Şahin M.T.; Türkdoǧan P.; Öztürkcan S.; Türel A.
    Basal cell carcinomas (BCCs) usually appear as solitary lesions, with or without having definite causes such as long term solar exposure, overtreatment with X-ray irradiation, skin types 1 or 2, and burn or wound eschars. Bowen's disease (BD), which usually appears as a permanent, progressive, flat, erythematous and squamous plaque, is a squamous carcinoma in situ. Solar exposure is the most important etiologic agent. The development of lesions, involving other than sun-exposed areas is favoured by chronic arsenic intake related to occupation or treatment. Porokeratosis of Mibelli (PM) is a rare disorder of keratinization, which developes in a long period of time, starting in childhood. There is risk of the development of squamous cell carcinoma (SCC) and/or BCC on the atrophic lesions of PM. We report a 64-year-old farmer who has developed coexisting BCC, BD and PM. In this article, we discussed etiologic, clinical and histopathologic aspects of these premalignant and malignant dermatoses, together with the importance of prevention from the harmful effects of the solar radiation.
  • No Thumbnail Available
    Item
    Does high-pressure carbon dioxide insufflation facilitate mucosal dissection in transanal endorectal pull-through? A rabbit model
    (2003) Genç A.; Taneli C.; Türkdoǧan P.; Yilmaz Ö.; Arslan O.A.; Mir E.
    The aim of the present study was to investigate whether high-pressure carbon dioxide insufflation facilitates mucosal dissection in the transanal endorectal pull-through (TEPT) operation performed in Hirschsprung's disease in a rabbit model. In the study, ten New Zealand rabbits were used. In six of the rabbits, CO2 under 50 mmHg pressure was insufflated into the submucosal area through a 25-gauge scalp needle inserted 0.3 cm over the dentate line. Two of the rabbits were taken for histopathological examination. In four rabbits, the TEPT operation was performed and in another four the operation was performed without CO2 insufflation. Histopathological examination in the CO2-insufflated group of rabbits showed that at transversal incisions mucosa was seen to be separated circumferentially from submucosa by high pressure CO2 and at longitudinal incision the separation was seen to be complete along the anal canal. It was noted that mucosal dissection was rapid, non-bloody and without induced mucosal tears or perforation; however, in the non-insufflated group the operation was time-consuming, bloody and more difficult to perform and needed meticulous care. In the present study, it was seen that submucosal high pressure CO2 insufflation in rabbits facilitates mucosal dissection in the TEPT operation and is easy to perform, time-saving and highly economical.
  • No Thumbnail Available
    Item
    Cyclic lymphocytic vasculitis associated with chronic lymphocytic leukemia
    (2004) Çabuk M.; Inanir I.; Türkdoǧan P.; Ceylan C.; Deǧirmenci M.; Türel A.; Özdemir E.
    Lymphocytic cutaneous vasculitis associated with a haematological malignancy has rarely been reported. Here, we describe a 61 year-old woman with chronic lymphocytic leukemia (CLL) who presented with cutaneous lesions on both hands. These lesions improved after all combination chemotherapy courses and recurred before each course. Repetitive skin biopsies revealed lymphocytic vasculitis. After 7 courses of chemotherapy, she had a complete remission. Skin lesions disappeared and did not recur. The cyclic pattern of lymphocytic vasculitis and its relation with CLL disease activity are interesting clinical features in this case. © 2004 Taylor & Francis Ltd.
  • No Thumbnail Available
    Item
    Bullous pemphigoid associated with prostate adenocarcinoma
    (2004) Öztürkcan S.; Ermertcan A.T.; Şahin M.T.; Türkdoǧan P.; Inanir I.; Lekili M.
    Bullous pemphigoid is a common autoimmune skin disease characterized by the presence of subepidermal blisters. It has been associated with underlying neoplasia in isolated reports. A 78-year-old man with generalized blisters was diagnosed as bullous pemphigoid on clinical, histopathological and direct immunofluorescence grounds. His free and total prostate specific antigen (PSA) levels were high and histopathological examination of a prostate specimen revealed prostate adenocarcinoma. We present this rare case to discuss the possible association between bullous pemphigoid and prostate adenocarcinoma.
  • No Thumbnail Available
    Item
    A case of traumatic ulceration mimicking spinocellular carcinoma; [Spinosellüler karsinomu taklit eden skalp yerleşimli bir travmatik ülser]
    (Turkiye Klinikleri, 2005) Şahin M.T.; Türel Ermertcan A.; Öztürkcan S.; Türkdoǧan P.
    In this article, it was aimed to show that ulcerations can develop not only following circulatory insufficiency, localized pressure, granulomatous degeneration, malignant tumors and local injections, but following exogenous traumas to skin as well. We present a 65-year-old male with a history of ulcer development on his nape following a cranial trauma 6 weeks before. A biopsy was taken to differentiate it from squamous cell carcinoma. Histopathologic examination revealed no tumor cell areas. Bacteriologic culture from ulcer floor revealed enterobacter. By enacting a combined systemic therapy with ciprofloxacin and gentamycin in addition to topical antiseptic therapy, the ulcer underwent complete remission in 15 days. This case is presented not only to draw attention to the possible clinical similarities between traumatic ulceration and squamous cell carcinoma, but also to emphasize the importance of differential diagnosis in the proper treatment of ulcers. Copyright © 2005 by Türkiye Klinikleri.
  • No Thumbnail Available
    Item
    Pilomatricoma: A late onset case in the neck
    (2005) Türel A.; Öztürkcan S.; Şahin M.T.; Güçlü G.; Türkdoǧan P.
    [No abstract available]
  • No Thumbnail Available
    Item
    A case of peristomal pyoderma gangrenosum following enterocutaneous fistula; [Enterokutan fistül açilimini takiben gelişen peristomal piyoderma gangrenozum]
    (2006) Şahin M.T.; Öztürkcan S.; Ermertcan A.T.; Erhan Y.; Türkdoǧan P.
    Pyoderma gangrenosum (PG) is an uncommon ulcerative skin disorder that is often associated with underlying systemic diseases, the most common of which is inflammatory bowel disease. It can rarely develop after minor trauma or surgery. Most reports of this condition developing after abdominal surgery have been reported following ostomy formation. Peristomal pyoderma gangrenosum (PPG), an unusual variant of PG, has been reported almost exclusively in patients with inflammatory bowel disease and is frequently misdiagnosed. We describe a 62-year-old woman with refractory PG, which has developed at surgical site of enterocutaneous fistula operation. As PG can mimic a necrotizing soft tissue infection, multiple unnecessary surgical procedures can be performed on such a patient, without improvement. A right diagnosis, based upon the distinctive clinical features and a compatible histology, is essential to avoid surgical procedure that often tends to exacerbate this unusual process.
  • No Thumbnail Available
    Item
    Erythromelanosis follicularis faciei et colli associated with keratosis pilaris in two brothers
    (2006) Ermertcan A.T.; Öztürkcan S.; Şahin M.T.; Türkdoǧan P.; Saçar T.
    Erythromelanosis follicularis faciei et colli is characterized by well-demarcated erythema, hyperpigmentation, and follicular papules. Since the original description, it has seldom been reported in the literature. We present two adolescent brothers who had this disorder associated with keratosis pilaris on the shoulders and the extensor surfaces of the arms. Dermatologic examination found brown-red pigmentation, erythema, and follicular papules on both maxillary, preauricular regions, and the cheeks. The lesions of the older brother were more prominent. Histopathologic examination of skin biopsy specimens taken from both brothers revealed hyperpigmentation of the basal layer, follicular plugging, dermal vascular dilatation and congestion, and perivascular inflammatory infiltration. We suggest that the coexistence of these two conditions in brothers implies a genetic inheritance and a possible relationship between the disorders. © 2006 Blackwell Publishing, Inc.