Browsing by Author "Türkdogan, P"

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    Wolf's isotopic response
    Türel, A; Öztürkcan, S; Sahin, MT; Türkdogan, P
    Lichen planus is a lichenoid disorder characterized by shiny, flat papules. In addition to the classical appearance, there are several variants. Zonal or zosteriform lesions have been described. A 25-year-old male with a complaint of increasing numbers of erythematous swellings on his left groin for twenty days was admitted to Our out-patient clinic. He had a history of herpes zoster in the same localization which had been treated with topical acyclovir two weeks prior to his admission. Dermatological examination revealed multiple, shiny erythematous, umblicated papules localized to the left inguinal region in a linear pattern. A biopsy was taken from the lesions. According to the clinical and pathological findings the diagnosis was zosteriform lichen planus, Zosteriform lichen planus is a rare variant of lichen planus; its differentiation from zona zoster and other linear dermatoses is difficult. We presented our case because of its rarity as a variant of lichen planus and its appearance in the area of healed herpes zoster as an isotopic response.
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    Generalized granuloma annulare in a patient with type II diabetes mellitus
    Sahin, MT; Türel-Ermertcan, A; Öztürkcan, S; Türkdogan, P
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    Erythromelanosis follicularis faciei et colli associated with keratosis pilaris in two brothers
    Ermertcan, AT; Öztürkcan, S; Sahin, MT; Türkdogan, P; Saçar, T
    Erythromelanosis follicularis faciei et colli is characterized by well-demarcated erythema, hyperpigmentation, and follicular papules. Since the original description, it has seldom been reported in the literature. We present two adolescent brothers who had this disorder associated with keratosis pilaris on the shoulders and the extensor surfaces of the arms. Dermatologic examination found brown-red pigmentation, erythema, and follicular papules on both maxillary, preauricular regions, and the cheeks. The lesions of the older brother were more prominent. Histopathologic examination of skin biopsy specimens taken from both brothers revealed hyperpigmentation of the basal layer, follicular plugging, dermal vascular dilatation and congestion, and perivascular inflammatory infiltration. We suggest that the coexistence of these two conditions in brothers implies a genetic inheritance and a possible relationship between the disorders.
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    Histopathological evaluation of the urethra after the Snodgrass operation
    Genç, A; Taneli, C; Günsar, C; Türkdogan, P; Yilmaz, Ö; Arslan, OA; Mir, E
    Objective To investigate the histopathological outcome of the incised urethral plate after tubularized incised-plate urethroplasty (the Snodgrass procedure to repair hypospadias) in a hypospadiac rabbit model, as it can produce meatal and neourethral strictures, and healing with scarring. Materials and methods The study comprised 10 male New Zealand White rabbits (2.2-2.4 kg); under general anaesthesia the ventral urethra was completely excised I cm from the meatus proximally and a model of hypospadias formed. A full-thickness incision was then made in the distal dorsal urethra and the two sides of the incision marked by Indian ink tattooing. After placing a feeding tube (5 F) as a urethral catheter, both urethral wings were sutured ventrally by a 7/0 polydioxanone running suture, and the penile skin approximated by 5/0 chromic catgut. At 21 days and 3 months after surgery the penises were harvested, assessed histopathologically. and compared with those from control untreated rabbits of the same age and weight. Results In the study group the incised area of the dorsal urethra was re-epithelialized; the regional tissue and vascularity were normal. Conclusion In this rabbit model the dorsal urethral incisions healed with no scar tissue; only the ventral suture lines had minimal fibrosis and inflammatory reaction.
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    Palmoplantar lichen planus presenting with vesicle-like papules
    Gündüz, K; Inanir, I; Türkdogan, P; Sacar, H
    Palmoplantar lichen planus is a rare, localized variant of the disease that may create difficulty in diagnosis if it is present as an isolated finding. Although several morphological patterns may be seen, plaques or small papules with compact hyperkeratosis are usually observed. We present a 25-year-old woman with a one-month history of slightly pruritic, red papules on her palms and soles. Dermatologic examination revealed numerous, asymptomatic, unscaly, red papules on her palms and soles, some of them resembling vesicles and white reticulate plaques on both sides of the buccal mucosa. The diagnosis was established by the typical histopathological features of lichen planus. Although resistant to topical corticosteroids, she responded well to systemic corticosteroid therapy, and no recurrence was observed during the follow-up period of one year.
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    Needle-guided shave excision with ultrasonographic assistance
    Seyhan, A; Tarhan, S; Türkdogan, P
    Background. A lack of control in the deep margin of shave excision is a drawback of this technique. Objective. To describe a more precise shaving technique by sonography with the use of a fine injector needle as a depth marker. Methods. After having examined the invasion levels of 40 benign skin lesions, a fine injector needle was intentionally threaded into the dermis horizontally just beneath the required shaving plane. Correct placement of the needle was ensured by sonographic examination after possible reinsertion trials. Large lesions needed several needles to be inserted. The tissue above the needles was then shaved off, whereas the deep dermal layer was protected. Results. Histologic examination revealed that 77% of superficial and intermediate-thickness lesions were removed totally without disturbing the derma-fat junction. Conclusion. The needle-guided technique was found to be effective in the control of the deep margin of shave excision.
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    A Case of Peristomal Pyoderma Gangrenosum Following Enterocutaneous Fistula
    Sahin, MT; Öztürkcan, S; Ermertcan, AT; Erhan, Y; Türkdogan, P
    Pyoderma gangrenosum (PG) is an uncommon ulcerative skin disorder that is often associated with underlying systemic diseases, the most common of which is inflammatory bowel disease. It can rarely develop after minor trauma or surgery. Most reports of this condition developing after abdominal surgery have been reported following ostomy formation. Peristomal pyoderma gangrenosum (PPG), an unusual variant of PG, has been reported almost exclusively in patients with inflammatory bowel disease and is frequently misdiagnosed. We describe a 62-year-old woman with refractory PG, which has developed at surgical site of enterocutaneous fistula operation. As PG can mimic a necrotizing soft tissue infection, multiple unnecessary surgical procedures can be performed on such a patient, without improvement. A right diagnosis, based upon the distinctive clinical features and a compatible histology, is essential to avoid surgical procedure that often tends to exacerbate this unusual process.
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    Transient eruptive seborrhoeic keratoses associated with erythrodermic pityriasis rubra pilaris
    Sahin, MT; Öztürkcan, S; Ermertcan, AT; Saçar, T; Türkdogan, P
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    A rare side-effect of systemic isotretinoin treatment
    Türel, A; Öztürkcan, S; Sahin, MT; Türkdogan, P
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    Trombosed solitary angiokeratoma of Mibelli simulating malignant melanoma
    Sahin, MT; Türel-Ermertcan, A; Öztürkcan, S; Türkdogan, P
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    Cyclic lymphocytic vasculitis associated with chronic lymphocytic leukemia
    Çabuk, M; Inanir, I; Türkdogan, P; Ceylan, C; Degirmenci, M; Türel, A; Özdemir, E
    Lymphocytic cutaneous vasculitis associated with a haematological malignancy has rarely been reported. Here, we describe a 61 year-old woman with chronic lymphocytic leukemia (CLL) who presented with cutaneous lesions on both hands. These lesions improved after all combination chemotherapy courses and recurred before each course. Repetitive skin biopsies revealed lymphocytic vasculitis. After 7 courses of chemotherapy, she had a complete remission. Skin lesions disappeared and did not recur. The cyclic pattern of lymphocytic vasculitis and its relation with CLL disease activity are interesting clinical features in this case.
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    Does high-pressure carbon dioxide insufflation facilitate mucosal dissection in transanal endorectal pull-through?: A rabbit model
    Genç, A; Taneli, C; Türkdogan, P; Yilmaz, Ö; Arslan, OA; Mir, E
    The aim of the present study was to investigate whether high-pressure carbon dioxide insufflation facilitates mucosal dissection in the transanal endorectal pull-through (TEPT) operation performed in Hirschsprung's disease in a rabbit model. In the study, ten New Zealand rabbits were used. In six of the rabbits, CO2 under 50 mmHg pressure was insufflated into the submucosal area through a 25-gauge scalp needle inserted 0.3 cm over the dentate line. Two of the rabbits were taken for histopathological examination. In four rabbits, the TEPT operation was performed and in another four the operation was performed without CO2 insufflation. Histopathological examination in the CO2-insufflated group of rabbits showed that at transversal incisions mucosa was seen to be separated circumferentially from submucosa by high pressure CO2 and at longitudinal incision the separation was seen to be complete along the anal canal. It was noted that mucosal dissection was rapid, non-bloody and without induced mucosal tears or perforation; however, in the non-insufflated group the operation was time-consuming, bloody and more difficult to perform and needed meticulous care. In the present study, it was seen that submucosal high pressure CO2 insufflation in rabbits facilitates mucosal dissection in the TEPT operation and is easy to perform, time-saving and highly economical.