Browsing by Author "Taşkin E.O."

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    Prevalence of prescription of psychotropic drugs and drug-drug interactions: The cytochrome P450 system; [Psikotrop i̇laç yazilma sikliǧi ve i̇laç etkileşimleri: Sitokrom P450 sistemi]
    (2003) Demet M.M.; Deniz F.; Şimşek E.; Taşkin E.O.; Deveci A.
    Objective: In this study, it is aimed to determine the prevalence of prescribing of psychotropic drugs and the combination of these drugs with the others, and to evaluate these combinations in terms of cytochrome p450 system interactions. Method: Out of 105 pharmacies in Manisa downtown area, fifty were visited. The sample consisted of 2164 prescriptions which had more than one drug. The combinations involved were recorded to a database and were evaluated according to cytochrome p450 system in terms of drug-drug interactions. Results: Of the whole prescriptions, 16.6% (360) had one or more psychotropic drug and the antidepressants were in first rank (9.3%) among psychotropic drugs. The number of prescriptions having any combination with possible drug-drug interactions was 19 (0.87% of the whole sample and 5.27% of the prescriptions which had psychotropic drug). Conclusion: It is a pleasing result that the amount of prescriptions that had possible drug-drug interactions in terms of cytochrome p450 system was small. Moreover, it is important that this study calls attention to possible drug interactions in terms of cytochrome system in addition to determine the present condition.
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    Which psychiatric label is more stigmatizating? "ruhsal hastalik" or "akil hastaligi"; [Hangi etiket daha damgalayici: ruhsal hastalik mi? Akil hastaligi mi?]
    (2004) Ozmen E.; Taşkin E.O.; Ozmen D.; Demet M.M.
    OBJECTIVE: To determine which of the two different labels, "ruhsal hastalik" or "akil hastaligi", used for psychiatric disorders by the public in Turkey is more stigmatizing. METHOD: This study was carried out at Celal Bayar University School of Health in Turkey. The questionnaire was designed by the researchers and applied to all students (n=272) present at the school on the day of application. The attitudes and opinions of students were investigated using case vignettes describing sczhizophrenia and major depression. RESULTS: It was seen that 0.8% of the students described the depression vignette as "akil hastaligi" while 78% described it as "ruhsal hastalik" with the schizophrenia vignette, 26% of students described it as "akil hastaligi" while 65% described it as "ruhsal hastalik". The participants who described the schizophrenia vignette as "akil hastaligi" stated that persons with symptoms like those of the schizophrenia vignette should not be free in the community (p<0.0001), they would not rent their house to a person with schizophrenia (p=0.013) and persons with schizophrenia are aggressive (p<0.0001); they had more negative attitudes than the participants who described it as "ruhsal hastalik" CONCLUSION: The results of this study suggest that the concepts "akil hastaligi" and "ruhsal hastalik" are used in different ways and the concept "akil hastaligi" has a more stigmatizing meaning. Therefore "akil hastaligi" should be avoided by health professionals when dealing with patients.
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    Prevalence of depressive disorders among patients with fibromyalgia seeking help for the first time and its relationship with alexithymia; [Fizik tedavi ve rehabilitasyon polikliniǧine ilk kez başvuran ve fibromiyalji tanisi konan hastalarda depresif bozukluklarin görülme sikliǧi ve aleksitimi ile ilişkisi]
    (2007) Taşkin E.O.; Tikiz C.; Gürlek Yüksel E.; Firat A.; Tüzün Ç.; Aydemir Ö.
    Objective: In this study, it was aimed to determine the prevalence of depression and its relationship with alexithymia among patients with fibromyalgia who apply to the Physical Therapy and Rehabilitation outpatient clinic for the first time. Methods: The research included 50 patients who applied to the Physical Therapy and Rehabilitation outpatient clinic for the first time and diagnosed as FM according to the American College of Rheumatology Scale. The subjects were evaluated with the SCID-I affective disorders module, 20-item Toronto Alexithymia Scale (TAS-20), 17-item Hamilton Depression Scale (HAM-D) and a demographic data form. Data were analyzed using t-test for continuous numerical parameters and chi-square test for categorized parameters. Pearson correlation test was used for determination of correlation between HAM-D and TAS-20 scores. Results: The prevalence of major depressive episode, depressive disorder NOS and dysthymia were found to be 44%, 10% and 14% respectively. None of the patients were seeking help for their depressive disorder and were using antidepressant treatment. TAS-20 scores of the patients with depression were higher (p=0.022) than scores of the non-depressive patients. Alexithymic patients had higher HAM-D mean values (p=0.035) and there was a positive correlation between TAS-20 and HAM-D scores (p=0.014). Conclusion: In fibromyalgia, the prevalence rate of depression is found to be significant. The prevalence rate of depression was even higher in alexithymic patients. Patients with fibromyalgia seem to have difficulty in experiencing their depression, and thus they do not seek psychiatric help. Therefore, these patients must be evaluated additionally for depression during the management of fibromyalgia.
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    Rapunzel syndrome: A case report; [Rapunzel sendromu: Olgu sunumu]
    (2007) Yilmaz Ö.; Genç A.; Taşkin E.O.; Dilşen Ş.; Kasirga E.; Taneli C.
    Bezoars are rare and often reported in patients with some psychiatric disorders. The Rapunzel syndrome is a rare form of gastric trichobezoar with a tail like extension into the intestine. 12 year old girl applied to the clinic with abdominal firmness. She was treated for alopecia areate one year ago. A firm, mobile and approximately 20 cm. diameter epigastric mass was palpated. A massively enlarged, firm stomach was encountered at surgical exploration. Gastrotomy revealed a large trichobezoar, which was taken out totally. She was referred to a child psychiatrist for assessment and therapy. Her diagnosis was major depression. In conclusion, trichophagy must be considered in children who suffer alopecia and psychiatric support must be provided.
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    Serum brain-derived neurotrophic factor levels in pain syndromes: A comparative study with major depression
    (Cukurova Univ Tip Fakultesi Psikiyatri Anabilim Dali, 2008) Taşkin E.O.; Aydemir Ö.; Deveci A.; Taneli F.; Selçuki D.; Cerrahoǧlu L.; Danaci A.E.
    Objective: In this study, it is aimed to compare the level of Brain-Derived Neurotrophic Factor (BDNF) of patients with migraine and fibromyalgia to that of depressive patients and healthy subjects in order to answer the question whether stress is related to pain syndromes. Methods: In the migraine group 27 patients and in the fibromyalgia group 19 patients without any previous antidepressant treatment and psychiatric diagnosis were included. In the depression group, 24 patients with at least eight weeks of antidepressant-free period were invited to the study. In the depression group no co-morbid diagnosis in the first axis was made. Twenty-six subjects without any previous psychiatric diagnosis and psychiatric treatment consisted the control group. For making diagnosis of depression and other first axis disorders Structured Clinical Interview for DSM- IV (SCID-I) was used in all study groups. For the assessment of the severity of depression Hamilton Depression Rating Scale (HAM-D) was applied. The diagnosis of migraine was made according to the criteria of International Headache Society. For the diagnosis of the fibromyalgia the criteria of American College of Rheumatology was used. The severity of pain was assessed with visual analogue scale (VAS) in the migraine and fibromyalgia groups. Serum BDNF was kept at -70°C before testing, and assayed with an ELISA Kit (Promega; Madison, WI, USA), after dilution with the Block and Sample solution provided with the kit. The data were subjected to Kruskal Wallis Test in the comparison of serum BDNF levels. Results: The serum BDNF level of the depression group (21.2±11.3 ng/ml) was statistically lower (p<0.0001) than the level of the migraine group (32.2±10.1 ng/ml), fibromyalgia group (30.7±8.9 ng/ml) and the control group (31.4±8.8 ng/ml). The level of BDNF was not significantly different in the migraine, fibromyalgia and control groups. There was no significant correlation between serum BDNF levels, and age and gender. In pain syndromes there was no signification correlation between serum BDNF levels, and mean scores of HAM-D and VAS (r= 0.085; p= 0.579 and r= 0.191; p= 0.204 respectively). Similarly there was no significant correlation between serum BDNF levels and HAM-D scores in the depression group (r=0.122; p= 0.579). Conclusions: Even though the pain syndromes were suggested to be associated with stress, in this present work, serum BDNF level as one of the markers of stress does not support this hypothesis. This might be related to the factor that in pain syndromes such as fibromyalgia or migraine, serum BDNF level may be affected by the alteration in peripheral platelet functions. Furthermore in a limited chronic stress serum BDNF levels tend to be not affected and this may play a significant role in our results.
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    The effect of locus of control on attitudes towards depression and schizophrenia; [Denetim odaǧinin depresyon ve şizofreniye yönelik tutumlara etkisi]
    (2008) Özmen E.; Özmen D.; Deveci A.; Taşkin E.O.
    Objective: There is no consensus about the effects of personality traits on attitudes toward mental illness. The purpose of this study was to determine the effect of locus of control on attitudes toward depression and schizophrenia. Methods: A cross-sectional survey of 196 university students was conducted. Attitudes toward depression and schizophrenia were assessed by a questionnaire designed by the authors and locus of control was measured by using Internal-External Locus of Control Scale developed by Rotter. Results: The items of the attitudes questionnaire were analyzed one by one to find out the effect of locus of control to attitudes toward mental disorders. There is a statistically significant difference between the participants who answered the item as 'I agree' and 'I don't agree' in one out of 15 items of depression part and two out of 15 items of schizophrenia part of the questionnaire. Discussion: Although many studies have shown that an individual's belief about locus of control has an important influence on his/her attitudes and behaviors, in this study it was seen that locus of control had no or minimal effect on attitudes toward depression and schizophrenia. But there is a need to implement new studies to illuminate the subject.
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    Attitudes of patients attending a psychiatric outpatient clinic towards depression; [Psikiyatri polikliniǧine bašvuran hastalarin depresyona y_sdonelik tutumlari]
    (2009) Taşkin E.O.; Gürlek Yüksel E.; Deveci A.; Özmen E.
    Objective: The aim of this study was to determine the knowledge and attitudes of patients attending a psychiatric outpatient clinic towards depression and factors that influenced them. Methods: This study is carried out on patients who attending Psychiatric Outpatient Clinic of Celal Bayar University Hospital. The study was carried out in 200 subjects who have been selected by systematic sampling method. In this study, a 32-item questionnaire designed for rating the attitudes toward depression by PAREM (Psychiatric Research and Education Centre) was used by adding one item to find out the attitudes toward depression. In addition, a 8-item sociodemographic questionnaire designed by authors and a 5-item questionnaire which was designed by authors and included the patients knowledge and opinions about their illness and illness characteristics of patients were applied. Results: Most of the subjects (83.5%) believed that "depression due to social problems". Half of subjects stated that they would not get married with a person with depression (50.5%). Twenty-eight of subjects stated that patients with depression might be aggressive. The patients suffering from a depressive episode toward depression answered the items "Mrs. F. has a somatic disease" (p=0.030), "Persons with depression don't recover completely" (p=0.003) and "persons with depression are aggressive" (p=0.029) as "I agree" more than the patients not suffering from a depressive episode; but answered the items "I can work with a person with depression" (p=0.004) and "I would get married to a person with depression" as "I agree" less than the patients not suffering from a depressive episode. Conclusions: Psychiatric outpatients have more correct knowledge than lay people about depression and treatment of depression. Most of the patients believed that depression is associated with social problems. Attitudes of the psychiatric outpatients toward patient with depression are more positive and more tolerant than lay people. However, patients with depressive episode have more negative and discriminative attitudes toward patients with depression and desire for social distance from patients with depression.
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    The relationship between separation individuation and depression in first grade students of university; [Üniversite birinci sιnιf öǧrencilerinde ayrιlma bireyleşme özellikleri ve depresyon illşkisi]
    (2009) Taşkin E.O.; Gürlek Yüksel E.; Özmen E.
    Objective: The purpose of this study was to find out the relationship between separation individuation and depression in university students. Methods: The sample consisted of 1026 first grade students of Celal Bayar University consisted the sample of this research a Sociodemographic Form, The Separation Individuation Test of Adolescence (SITA) and Beck Depression Inventory (BDI) were used in this study. Statistical significance of the relationship between SITA subscale scores and BDI scores was assessed by Pearson correlation test and between SITA subscale scores and depression according to the cut-off values of BDI was assessed by using Student's t-test. Results: 20.6% of the students had depression according to the cut-off values of BDI. The mean score of the BDI was 10.98±9.02. There was a statistically significant negative correlation between the scores of SITA subscales 'peer enmeshment', 'practicing-mirroring' and 'healthy separation' which indicates positive separation individuation process and BDI scores when there was a statistically significant positive correlation between the scores of SITA subscales which indicates difficulties with separation individuation issues 'separation anxiety', 'engulfment anxiety', 'dependency denial' and 'rejection expectancy' and BDI scores. The scores of 'separation anxiety', 'engulfment anxiety', 'dependency denial' and 'rejection expectancy' subscales of SITA were significantly higher in the students with depression according to the cut-off values of BDI when healthy separation subscale scores were significantly higher in the students with depression according to the cut-off values of BDI. Conclusion: In this study, it has seen that there was a relationship between depression and separation-individuation process in adolescence. Difficulties with separation individuation issues in adolescence, in other words failure in achieve developmental tasks during adolescence could cause depression.
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    Risk factors for delaying treatment seeking in obsessive-compulsive disorder
    (2010) Demet M.M.; Deveci A.; Taşkin E.O.; Erbay Dündar P.; Türel Ermertcan A.; Mizrak Demet S.; Bayraktar D.; Öztürkcan S.
    Background: Despite the multiple alternatives of treatment, it is well known that patients with obsessive-compulsive disorder (OCD) delay seeking treatment. In this study, the aim was to determine the risk factors for delaying treatment seeking in OCD patients. Methods: The sample consisted of 132 OCD who completed the Yale-Brown Obsessive-Compulsive Scale, Yale-Brown Obsessive-Compulsive Scale Symptom Checklist, and Beck Depression Inventory. Results: In univariate analyses with risk evaluation, income level, being single or divorced, having a history of psychiatric treatment, poor insight for the symptoms, and obsessions of hoarding were the variables that were found to be significant. In the regression model, history of psychiatric treatment and duration of OCD were the 2 variables that remained statistically significant. Conclusion: This was the first study wherein the sample included patients who were recruited from a nonpsychiatric department: the dermatology clinic. Application to dermatology has not been determined as a risk factor for delaying treatment seeking in OCD patients. © 2010 Elsevier Inc. All rights reserved.