Browsing by Author "Tas, M"

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    Effects of eccentric exercise-induced delayed onset muscle soreness on endoplasmic reticulum stress-related markers
    Dogru, Y; Varol, SR; Nalcakan, GR; Akyuz, M; Tas, M; Ulman, C
    Short Communications: Apelin, pentraxin3 (PTX3), and interleukin6 (IL6) parameters are known as inflammation markers and found to be related to endoplasmic reticulum (ER) stress. The aim of the study was to investigate the effect of eccentric exercise-induced delayed onset muscle soreness (DOMS) on ER stress-related markers in young athletes. Objectives and Methods: ER stress and DOMS-related blood markers, maximal strength level, and rate of perceived exertion using the visual analog scale (VAS) were assessed before, immediately after, 24, 48, and 72 h after the muscle damage protocol. Results: IL6 peaked 24 h after while creatine kinase and lactate dehydrogenase enzyme levels reached their peaks at 72 h after the protocol. The level of apelin continued to increase throughout the four measurements, and PTX3 peaked at 24 h, and then declined to the levels before the protocol but the differences were not significant. The significant decrease in the strength and the significant increase in VAS continued 48 h after the protocol. Conclusion: ER is activated and ER stress occurred, due to increases in IL6, PTX3 and apelin levels after the test protocol concluded that a single vigorous eccentric exercise should be avoided in harmful effect on health as parallel with Physical Activity Guidelines.
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    The effects of various strength training intensities on blood cardiovascular risk markers in healthy men
    Akyüz, M; Dogru, Y; Nalcakan, GR; Ulman, C; Tas, M; Varol, R
    Objectives Regular physical exercise, especially aerobic exercise, is known to have a protective effect on cardiovascular health. The aim of this research is to look at the impact of two separate resistance training programs on blood biomarkers that are associated with the early detection of cardiac risk. Methods Forty-five male participants (mean 41 years) were randomly divided into three groups: The low-intensity resistance exercise group (LIEG), the moderate-intensity resistance exercise group (MIEG), and the control group (CG). The programs were implemented three times a week and in two sets. MIEG consisted of 8-10 repeats at 70-80% density of one repetition maximum load (1RM), while LIEG consisted of 15-17 repeats at 50-60% density of 1RM. CG did not participate in any exercise program. Two-factor mixed-design ANOVA assessed the data. Results Before, fourth week, and after the exercise program in repeated measurements, there was a significant decrease in body mass (-1.7%), body mass index (-1.7%), apelin (-44%), and pentraxin 3 (-39%) levels in MIEG (p < 0.05). Additionally, our study noted a decrease in pentraxin 3 (-25%, p < 0.05) and interleukin 6 (-21%) levels, while there was an increase in creatine kinase (18%), and lactate dehydrogenase (7.4%) levels in LIEG. Strength levels improved significantly in exercise groups. Conclusions Eight weeks of moderate-resistance training can potentially reduce the cardiovascular risk in healthy men.
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    The Effect of Combined Training on Rowing Ergometer Performance in Rowers
    Koparal, A; Bilgin, Z; Tas, M
    Strength and endurance have an important place in rowing performance. Short-term and high-intensity training methods provide more effective development than traditional strength and endurance training. In this study 24 male participants, ages between 18-22 yrs, actively involved in the rowing team at the Naval Academy were included. Participants were randomly divided into 2 groups as 12 subjects and 12 controls. Anthropometric measurements, heart rate, strength and rowing ergometer tests of the subject group were performed before and after the 8-week training period. The control group only participated in the measurements in the first and last week. Resting heart rate, right-left handgrip strengths, back strength, leg strength, ReMaxP, ReMeanP, Re500m, Re1000m, Re1500m, and Re2000m variables of the subject group were significant in favour of the post-test. The control group also had significant differences in favour of the post-test for the same variables except for Re500m. When the two groups were compared, significant differences were found in favour of the subject group for right-left handgrip strengths, back strength, leg strength, ReMeanP, Re500 m. Conclusively, it could be said that the strength and endurance developments of athletes who use a combined training program are better and the performance and training levels of rowers can be increased.
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    Comparison of blood carbonic anhydrase activity of athletes performing interval and continuous running exercise at high altitude
    Tas, M; Senturk, E; Ekinci, D; Demirdag, R; Comakli, V; Bayram, M; Akyuz, M; Senturk, M; Supuran, CT
    The effects of high-intensity interval and continuous exercise on erythrocytes carbonic anhydrase (CA, EC 4.2.1.1) activity levels were scarcely investigated up until now. Here we present a study focused on the CA activity from erythrocytes of athletes experiencing interval and continuous training for 6 weeks, during cold weather and at high altitude (> 1600 m). We observed a 50% increase in the blood CA activity at the second week after initiation of the training in both interval and continuos running groups, whereas the control group did not experience any variation in the enzyme activity levels. In the trained individuals a mild decrease in their body mass, BMI and an increased were also observed. The CA activity returned at the basal values after 4-6 weeks after the training started, probably proving that a metabolic compensation occurred without the need of an enhanced enzyme activity. The unexpected 50% rise of activity for an enzyme which acts as a very efficient catalyst for CO2 hydration/bicarbonate dehydration, such as the blood CA, deserves further investigations for better understanding the physiologic basis of this phenomenon.
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    Effects of high-intensity interval training program on pituartry function in basketball players: a randomized controlled trial
    Soslu, R; Uysal, A; Devrilmez, M; Çuvalcioglu, IC; Dogan, AA; Karaburgu, S; Tas, M
    The aim of the study was to determine how the short high-interval training program affects cortisol levels in basketball players. A total of 27 male basketball players volunteered for the study and were randomly assigned to one of two groups: Control Group (CG) (n = 13, mean age; 20,56 +/- 1,45 years, mean height; 184,53 +/- 6,65 cm) and Experimental Group (EG) (n = 14, mean age; 20,71 +/- 2,12 years, mean height; 86,51 +/- 8,21 cm). The experimental group received a 7-week interval training program. Blood samples were taken at the beginning and end of the study. Cortisol, Adrenocorticotropic Hormone, Triiodothyronine, Tetraiodothyronine, Parathyroid Hormone, Thyroid Stimulating Hormone, Insulin, and Glucose levels were measured of the EG and CG. To test the differences between groups and compare the effects of pre and post-intervention, a two-way ANOVA for repeated measures was used. Consequently, the post-test levels of TSH, PTH, and ACTH in the exercise group showed a significant difference when compared to the pre-test values (p = 0.000). Moreover, the post-test levels of Glucose, Cholesterol, Triglyceride, HDL, and Mg in the exercise group showed statistical significance when compared to the pre-test values (p = 0.000). Significant differences were seen in the post-test PTH and ACTH levels of the control group when compared to the pre-test values (p = 0.000). Furthermore, the exercise group showed significant differences in post-test values for HDL and Cholesterol compared to the pre-test (p = 0.000). In addition, when comparing the post-test values and pre-test values of both the exercise group and the control group, it was found that all parameters, with the exception of Ca, exhibited substantial differences in favor of the exercise group. It may be claimed that the implementation of interval training has favorable outcomes on pituitary function parameters. Additionally, the regulation of energy consumption during exercise is favourably influenced, along with the reduction of physiological stress resulting from prolonged exercise.
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    Carbonic Anhydrase Activity as a New Parameter in Exercise Physiology
    Tas, M; Sentürk, E; Sentürk, M; Çomakli, V; Demirdag, R; Bayram, M; Akyüz, M; Göktepe, M
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    Comparison of Glutathione Reductase and Glutathione S-Transferase Levels of Two Different Running Training Groups
    Tas, M; Sentürk, E; Sentürk, M; Demirdag, R; Çomakli, V; Akyüz, M; Soslu, R; Akyüz, Ö; Bayram, M