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  1. Home
  2. Browse by Author

Browsing by Author "Tekin C."

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    Cardioprotective effect of calcium dobesilate during open-heart surgery
    (2006) Iskesen I.; Saribulbul O.; Cerrahoglu M.; Onur E.; Tekin C.; Sirin H.
    Objective - The purpose of this double-blind, controlled, prospective randomized study was to investigate the possible effects of the preoperative use of calcium dobesilate (CLS2210) on the biochemical markers of myocardial injury during open-heart surgery, and to determine if it has any myocardial protective effects. Methods - Twenty-four patients undergoing elective cardiac surgery were included in this study and randomized into two groups. CLS2210 was given orally to 12 patients for 14 days before the operation (CD group), but not to the other 12 patients (control group). Serum CK, CK-MB, myoglobin and troponin-T levels were measured from venous blood samples before and after the operation for evaluation of the effect of this drug against myocardial damage. Blood samples were also taken from the radial artery and the coronary sinus before the institution of cardiopulmonary bypass (CPB), and 2 and 15 minutes after the removal of the cross-clamp in order to measure the lactate levels and calculate the lactate extraction of the myocardium. Results - First, CK-MB levels in patients of the CD group were significantly lower than those of the control group (p < 0.05) at the 2nd and 18th postoperative hour. Second, myoglobin and troponin-T levels in the CD group were significantly lower than those of the control group (p < 0.05) at the 2nd, 18th and 48th postoperative hour. Third, there was a significant difference in lactate extraction calculation values between the groups at the 2nd minute after removal of the cross-clamp (p < 0.05). Conclusions - We concluded that preoperative use of CLS2210 has some beneficial effects in protecting the myocardium and decreasing the myocardial injury during the cardioplegic arrest period in open-heart surgery.
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    N-terminal proBNP levels can predict cardiac failure after cardiac surgery
    (2007) Cerrahoglu M.; Iskesen I.; Tekin C.; Onur E.; Yildirim F.; Sirin B.H.
    Background: The aim of this study was to evaluate the relationship between the preoperative N-terminal pro-B-type natriuretic peptide (NT-proBNP) level and the need for the inotropic support in the early postoperative period of patients undergoing coronary artery bypass graft surgery. Methods and Results: The patients were divided into 2 groups: NT-proBNP level <220 pg/ml (group A, n=26) or >220 pg/ml (group B, n=26). The normal value for NT-proBNP level was accepted as <220 pg/ml. The cardiac output was measured on arrival in intensive care and at the 16th hour. The groups were compared with respect to early postoperative hemodynamic measurements, urinary output, use of inotropic agents and requirement for additional cardiac-assist devices. Left ventricular ejection fraction, cardiac output and cardiac index were lower in group B and inotropic agents were used for a longer period of time and at higher doses in this group (p<0.05). Conclusion: Measurement of the NT-proBNP level in the period before cardiac surgery can indicate the postoperative prognosis of the patient and may be a predictor of the need for postoperative inotropic treatment.
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    Gender, Islam and nativism in populist radical-right posters: visualizing ‘insiders’ and ‘outsiders’
    (Routledge, 2022) Sayan-Cengiz F.; Tekin C.
    Sayan-Cengiz and Tekin explore the visual communication strategies of Western European populist radical-right (PRR) parties in disseminating nativist, anti-migrant and Islamophobic agendas through gendered visual representations. It is widely argued that the PRR homogenizes and dichotomizes both ‘native’ and Muslim migrant cultures through an ostensibly liberal discourse of respect for women’s rights and freedoms in order to mainstream their exclusionary position towards Muslim migrant communities. However, there is a void in the literature in terms of accounting for how visual communication strategies are used in this process. The authors here argue that looking into the visual representations of Muslim migrant and ‘native’ bodies in the PRR parties’ visual communication materials is crucial for understanding the PRR’s gendered cultural constructions of both Muslim migrant ‘outsiders’ and native ‘insiders’. Focusing on the campaign posters for the Alternative für Deutschland (AfD) in Germany, the Rassemblement National (RN) in France, and the Partij voor de Vrijheid (PVV) in the Netherlands using a social semiotic approach, their study suggests that Muslim migrants are represented as alien Others, but that there is also a significant difference between representations of migrant women as ‘victims’ and men as ‘aggressors’. On the other hand, ‘native’ women are represented as the embodiment of authentic national identities, as either reproducers or defenders of the nation. ‘Native’, heterosexual men do not often appear in the posters, pointing to the position of power that they hold in the PRR’s imagination. That is, they are the designated spectators and addressees of visual communication materials, rather than objects of representation. © 2022 Informa UK Limited, trading as Taylor & Francis Group.

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