Browsing by Author "Temeltaş G."
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Item Effects of extracorporeal shockwave lithotripsy at different stages of pregnancy in the rabbit(Mary Ann Liebert Inc., 1997) Gümüş B.; Lekili M.; Kandiloǧlu A.R.; Işisaǧ A.; Temeltaş G.; Nazli O.; Büyüksu C.Although SWL is now the most common treatment modality for urinary tract stone disease, it is not regarded as a safe method for pregnant patients because of its potential harmful effects on fetus. Using a rabbit model, we investigated whether SWL might cause fetal injury when administered at various developmental stages. Two groups of pregnant rabbits were given 1000 shockwaves either early or late in the gestational period. Time-matched controls did not receive shockwaves. After spontaneous labor, all newborn rabbits were counted, weighted, and measured, and specimens were taken from organs and examined histopathologically. The numbers, weights, and diameters of the newborns in each group were similar. There was no notable histopathologic finding in the heart and brain specimens of any of the newborns, whereas noticeable congestion and multiple focal intraparanchymal microhemorrhages were found in lungs, livers, and kidneys of the animals that had been exposed to shockwaves early in gestation. In conclusion, this study shows that SWL is not a safe treatment in early pregnancy.Item Serum levels of total acid phosphatase, prostatic acid phosphatase, total and free prostate-specific antigen in patients within chronic hemodialysis program(2001) Gümüş B.; Lekili M.; Uyanik B.S.; Temeltaş G.; Büyüksu T.; Kürşat S.Objective: To investigate the effect of terminal renal failure with chronic hemodialysis on prostatic disease markers [total acid phosphatase (TAP), prostatic acid phosphatase (PAP), prostate-specific antigen (PSA) and free prostate-specific antigen (fPSA)]. Patients and Method: Total acid phosphatase (TAP), prostatic acid phosphatase (PAP), prostate-specific antigen (PSA) and free prostate-specific antigen (fPSA) were measured in 28 patients over 40 years of age on terminal renal failure with chronic hemodialysis. Correlation was calculated between the dialysis duration and prostatic disease marker levels. Results: There was no evidence of artefactual elevation of prostatic disease markers. TAP, PAP, PSA and fPSA levels were in the normal range in all of the patients. However, PSA and fPSA levels decreased as the dialysis duration increased. Conclusion: Prostatic disease markers were useful in the routine screening of men receiving long-term dialysis, but the clinicians should be on alert when the dialysis duration increases.Item Comparison of the nuclear matrix protein 22 with voided urine cytology in the diagnosis of transitional cell carcinoma of the bladder(2004) Lekili M.; Şener E.; Demir M.A.; Temeltaş G.; Müezzinoǧlu T.; Büyüksu C.Several urinary markers for transitional cell carcinoma have been investigated, including urine cytology, bladder tumor antigen, autocrine motility factor receptor and fibrin degradation products. Unfortunately, they have poor overall sensitivity. The United States Food and Drug Administration have recently approved nuclear matrix protein (NMP 22) for the detection of occult or rapidly recurring disease after transurethral resection of bladder tumor. The objective of the current study was to assess the sensitivity of NMP 22 for the detection of bladder carcinoma, as well as to correlate the NMP 22 values with multiplicity of tumor, tumor size, configuration, stage and grade respectively. A total of 78 patients (38 with bladder cancer) provided a urine sample which was divided into appropriate aliquots for each of urine cytology and NMP 22. Comparative results demonstrate a clear superiority of NMP 22 in bladder cancer detection (52.6% vs 31.6% sensitivity), while specificity was in favor of urine cytology (100% vs 82.5%). For superficial tumors, sensitivity was 78.5% for NMP 22 and 41.6% for cytology and for invasive cancers, sensitivity was 90% for NMP 22 and 60% for cytology. Urinary NMP 22 levels were significantly correlated with tumor grade and were significantly higher in large tumors than small tumors. NMP 22 test results showed sufficient sensitivity in comparison with urine cytology for the detection of transitional cell carcinoma. However, we do not think that it is a useful tool as a substitute for endoscopic examination for the detection and surveillance in bladder cancer.Item Evaluation of pain caused by urethrocystoscopy in patients with superficial bladder cancer: A perspective of quality of life(2005) Müezzinoǧlu T.; Ceylan Y.; Temeltaş G.; Lekili M.; Büyüksu C.Aim: The aim of this study is to evaluate patients' tolerance to pain caused by urethrocystoscopy (UCS) in both diagnosis and the period of follow-up in patients with superficial bladder cancer, and to evaluate these results with respect to quality of life. Patients and Methods: Between March 2003 and October 2004, 66 patients with bladder cancer or hematuria underwent UCS and recorded their overall pain level. Results: The mean age was 60.4 (range 26-83) years. UCS was done only one time in 22 patients for the diagnosis of etiology of hematuria and was done 4 times in 44 patients every 3 months for bladder cancer follow-up. The mean pain scores on first, second, third, and fourth UCS were 4.3±2.2, 4.7±2.5, 4.68±2.45, and 5.1±2.5, respectively. Statistically significant differences were found among mean pain scores of patients on first, third, and forth cystoscopic examinations (p < 0.05). No correlation was found between age and pain scores in this study group (p > 0.05). Conclusion: UCS is a painful surgical procedure and pain tolerance was not observed on repeated UCS. Therefore urologists need to use more effective anesthetic methods to provide better patients' tolerance to pain and quality of life during the endoscopic procedure. © 2005 S. Karger GmbH.Item Is it necessary to use sexual health inventory for men (SHIM) routinely?(2005) Temeltaş G.; Gündüz M.I.; Ceylan Y.; Gümüş B.H.; Büyüksu C.This study was conducted to evaluate the prevalence of erectile dysfunction (ED) according to the Sexual Health Inventory for Men (SHIM) and its relationship with age and education. Six hundred and thirty-nine male patients aged ≥ 20 years attending a urology clinic were studied. After a detailed history and physical examination, all patients were evaluated with SHIM. Scores were categorized into 5 groups: severe (1-7), moderate (8-11), mild-moderate (12-16), mild (17-21) and normal (22-25). The patients were classified into three groups according to their application to the urology clinic: A - patients attending specifically for ED; B - patients not ED based on SHIM and attending not for ED; C - patients ED based on SHIM, but attending not for ED. In addition, patients were partitioned into 3 age groups according to their age: 20-35, 35-55 and > 55 years. Educational levels were of 2 groups: lower education and higher education. Erectile dysfunction was determined in 3.7% in the 20-35 years group, 55% in 35-55 years and 41% in > 55 years (P < 0.01). In men having ED through SHIM and attending not for ED, the ratio of ED was higher in the lower education than in the higher education groups (p = 0.01). SHIM is a diagnostic tool used for ED, and routine application of SHIM for patients attending the urology clinic is advisable.Item Sexual dysfunction in patients with psoriasis(2006) Türel Ermertcan A.; Temeltaş G.; Deveci A.; Dinç G.; Güler H.B.; Öztürkcan S.Psoriasis can have a significant impact upon sexual function. The aim of this study was to investigate sexual function in females and males with psoriasis and to evaluate whether coexistent depression has an additional negative effect on sexual function in these patients. A total of 66 female subjects (39 with psoriasis and 27 healthy volunteers as a control group) and 70 male subjects (39 with psoriasis and 31 healthy volunteers as a control group) were enrolled in the study. A Psoriasis Area and Severity Index (PASI) was used to determine the severity of psoriasis for the patient groups. The Female Sexual Function Index (FSFI) was used to assess female sexual function and the International Index of Erectile Function (IIEF) was used to evaluate male sexual function. Quality of life was assessed with the Dermatology Life Quality Index (DLQI). The diagnosis of depression was made according to the Structured Clinical Interview for DSM-IV (SCID-I) interview and Hamilton Depression Rate Scale (HDRS) was used for grading depression. FSFI total score was found to be significantly decreased in female psoriatic patients without depression and psoriatic patients plus depression compared with healthy controls (24.09 ± 5.33 vs. 24.25 ± 4.52 vs. 28.12 ± 3.48, respectively, p = 0.004). However, FSFI score was not significantly different between patients with psoriasis without depression and those with psoriasis plus depression (p > 0.05). IIEF total score was also found to be significantly decreased in male psoriasis without depression and psoriasis plus depression patients compared with healthy controls (54.21 ± 13.07 vs. 52.0 ± 14.73 vs. 61.69 ± 9.49, respectively, p = 0.023). The difference in IIEF scores between patients with psoriasis without depression and in those with psoriasis plus depression were not statistically significant (p > 0.05). The results of the study demonstrated that patients with psoriasis, especially females have distinct sexual dysfunction compared with healthy controls, and coexistent depression has no additional negative effect on sexual dysfunction in our patients. Patients with psoriasis should be evaluated in terms of sexual function in order to provide a better quality of life. © 2006 Japanese Dermatological Association.Item The relationship between serum steroid hormon levels and I-PSS, prostatic volume, residual urine: A community based study; [Serum steroid hormon düzeyleri ile I-PSS, prostat aǧirliǧi ve artik i̇drar baǧintisi: Topluma dayali bir çalişma](2007) Temeltaş G.; Müezzinoǧlu T.; Akar Z.; Lekili M.; Büyüksu C.Introduction: It is evaluated that endocrinolgical effect is the most reliable factor for development of histological and clinical BPH which is the common disease in older males. Materials and Methods: In our study, we investigated the relationship between BPH incidence and steroid hormone levels by using the criteria of I-PSS, residual urine and prostatic volume in the men over 40 in a rural town. Total and free testosterone, estradiol, dihidroepiandosteron sulfate, sex hormone binding globulin, FSH and LH levels were analyzed. I-PSS and quality of life scores were evaluated. Results: Mean FSH, LH, DREAS, SHBG, E2, tT and fT levels were 11.03±11.06 mIU/ml (0.9-83.7), 9.26±18.7 mIU/ml (0.7-200), 114, 86±68.3 pg/dl (30-417), 55.28±31.4 nmol/L (2-180), 23.03±9.05 pg/mL (20-46.1), 3.9±1.82 ng/dl (0.2-16) and 13.7±4.7 pg/mL (0.6-31.6). Mean I-PSS, QoL, residual urine and prostatic volume were 4.7±5.9 (0-30), 0.7±1.3 (0-6), 21.5±30.7 (0-295) ml and 24.4±11.4 (9-82) gr. respectively. With Pearson correlation system; age, I-PSS, QoL, residual urine and prostatic volume were well correlated with each other (p<0.05). While age increased, FSH and SHBG increased significantly (r=0.2979 and r=0.3642). On the other hand, DHEAS (r=0.4792) and fT (r=0.3306) decreased, while age increased. There was no correlation between E2, LH, tT. SHBG and age. When it is accepted as all the men with their I-PSS over 7 has BPH; fT levels were statistically lower (14/ 12.3, p=0.009) and their SHBG levels were higher than those without BPH (52.5/64.8, p=0.029). Conclusion: If the diagnosis of BPH is determined with the different combination of I-PSS, residual urine and prostatic volume, no significant data was revealed between serum steroid hormone levels and BPH. fT levels were significantly lower in men with high I-PSS than those with low I-PSS.Item A relationship of sex hormone levels and erectile dysfunction: Which tests should be done routinely?(2007) Müezzinoǧlu T.; Gümüş B.; Temeltaş G.; An Z.; Büyüksu C.Purpse: In this study, the relationship between sex hormone levels and erectile dysfunction (ED), as well as the necessity of routinely measuring sex hormone levels were evaluated. Materials and Methods: This study included one hundred patients admitted to a urology clinic for sexual dysfunction. To determine the hormone levels, following the history (included IIEF-5 score) and physical examination, triple blood samples were collected at intervals of 15 minutes between 08:00 and 10:00 am. Total and free testosterone, prolactin, follicle stimulating hormone and leteinizing hormone levels were studied. Results: Mean ago was 43 (23 - 80) years. IIEF-5 score was less than 21 [9.8 - 4.3 (3 - 19)] in all study groups. There was a statistically significant correlation between tT and FSH, as well as between LH and FSH in Pearson (r = - 0.513, p < 0.001, respectively) and also in Spearman tests (r = - 0.224, p = 0.042 and r = - 0.459, p < 0.001, respectively). However, there was no correlation between age and serum hormone levels (p > 0.05). Of the 100 patients, 18 (18%) had low tT, 77 (77%) had normal and 5 (5%) had high tT levels. No statistically significant correlation was found between decreased libido and tT levels (p > 0.05). Twelve (66.6%) of the 18 patients with low tT had normal libido. Conclusion: Analyzing the medical history in detail and performing a thorough physical examination can reduce the need for excessive studies and consultations, and enables patients to save time and costs.Item The relationship between smoking and lower urinary tract symptoms: Community based study; [Si̇gara alişkanliǧi i̇le alt üri̇ner si̇stem yakinmalari arasindaki̇i̇li̇şki̇: Topluma dayali çalişma](2007) Temeltaş G.; Müezzinoǧlu T.; Üçer O.; Lekili M.; Büyüksu C.Introduction: The studies, investigated the relationship between smoking and benign prostatic hyperplasia (BPH), are commonly clinically based. We aimed that whether smoking has any effect on BPH and/or lower urinary tract symptoms in a community based fashion. Materials and Methods: The forms of international prostate symptom score (I-PSS), quality of life (QoL) and asking smoking addiction were fulfilled by 255 men over 40 years old living in a small town of Manisa. Meanwhile prostatic volume and post-voiding residual urine volume calculations with ultrasound were evaluated. Results: While the degree of smoking (package/year) increased, I-PSS, QoL and residual urine volume slightly increased, but no correlation found with Pearson co-efficient. Although no statistically significant relation was observed, prevalence of BPH in this population was higher in smoking men than non smoking men. Conclusion: In this study, although no statistically correlation was found between smoking and BPH, it is observed that smoking is slightly effect the prevalence of BPH. It may be speculated that smoking has variable effects on sex steroids.Item Sexual dysfunction in patients with chronic hand eczema in the Turkish Population(Blackwell Publishing Ltd, 2007) Ergün M.; Türel Ermertcan A.; Öztürkcan S.; Temeltaş G.; Deveci A.; Dinç G.Introduction. Hand eczema can cause considerable psychosocial disorders, such as anxiety, depression, and difficulties at work, and it may also cause sexual dysfunction. Aim. The aim of this study was to investigate sexual function in patients with hand eczema and to find out whether concomitant depression has an additional negative effect on sexual function in these patients. Main Outcome Measures. Sexual functions were evaluated in hand eczema patients. Methods. Ninety-one female (43 patients vs. 48 controls) and 79 male (45 patients vs. 34 controls) subjects were enrolled in the study. Hand eczema severity index was used to determine severity of hand eczema. The Female Sexual Function Index (FSFI) and the International Index of Erectile Function (IIEF) were used to assess sexual function. Quality of life was assessed with the Dermatology Life Quality Index. Diagnosis of depression was made based on the Structured Clinical Interview for the DSM-IV, while the Hamilton Depression Rate Scale was used for grading depression. Results. Among 43 female subjects with hand eczema, 26 had depression (60.46%); of the 45 male patients, 11 had depression (24.44%). FSFI total score was found to be significantly decreased in female patients with both eczema and depression compared with controls (20.84 ± 9.19 vs. 24.04 ± 3.40, P < 0.05). FSFI total score was found to be significantly decreased in female patients with both eczema and depression compared with those without depression (20.84 ± 9.19 vs. 22.23 ± 5.82, P < 0.05). IIEF total score was also found to be significantly decreased in male patients with or without depression compared with controls (52.36 ± 14.83 vs. 59.88 ± 5.65 vs. 62.03 ± 11.04, P < 0.05). Conclusions. The results of the study demonstrated that patients with hand eczema had sexual dysfunction, and concomitant depression had an additional negative effect on sexual dysfunction. Patients with hand eczema should be evaluated with regard to sexual function and depression to provide a better quality of life. © 2007 International Society for Sexual Medicine.Item Sorafenib-induced erythema multiforme in metastatic renal cell carcinoma(2009) Bilaç C.; Müezzinoǧlu T.; Ermertcan A.T.; Kayhan T.C.; Temeltaş G.; Özütrkcan S.; Temiz P.Sorafenib is a new therapeutic agent being used in metastatic renal cell carcinoma, hepatocellular carcinoma, and malignant melanoma. The most frequently seen cutaneous side effects due to sorafenib are erythema, exfoliative dermatitis, acne vulgaris, and flushing. Folliculitis, eczema, and erythema multiforme are other, rare side effects of sorafenib. A 59-year-old man underwent left radical nephrectomy due to renal cell carcinoma 8 months ago, and after the operation he received immunochemotherapy and then sorafenib. On the third day of sorafenib therapy his lesions occurred. His dermatologic examination revealed multiple erythematous papules on his neck, arms, and legs and bullae and iris lesions on his palms and soles. He was diagnosed as having erythema multiforme. In the literature we found only 1 other erythema multiforme case due to sorafenib. We present this interesting case to show and discuss cutaneous side effects of sorafenib, especially erythema multiforme as a very rare cutaneous side effect. © 2009 Informa UK Ltd.Item The comparison of MRI findings with severity score of incontinence after pubovaginal sling surgery; [Pubovajinal sling operasyonu sonrası inkontinans şiddet indeksi ile MRG bulgularının karşılaştırılması](Turkiye Klinikleri Journal of Medical Sciences, 2010) Tarhan S.; Gümüş B.; Temeltaş G.; Yilmaz Ovali G.; Serter S.; Göktan C.Aim: To investigate the relationship between postoperative MRI findings and the severity score of incontinence in patients treated with pubovaginal sling surgery. & Materials and methods: Fifty-two female patients treated with pubovaginal slings were included in the study. These patients' severity scores of incontinence were evaluated in the postoperative 6th month. All the patients were examined using MRI on the same day. A T2-weighted sagittal image of the midline structures, including the symphysis, urethra, and coccyx, was obtained at rest and at maximal strain. The mobility of the bladder floor and change in the posterior urethrovesical angle were calculated for each patient. Relationships between the severity score of incontinence and mobility of the bladder floor and change in the posterior urethrovesical angle were analyzed using Spearman's rank correlation coefficients by means of SPSS.& Results: A positive correlation was found between the severity score of incontinence and the mobility of the bladder neck and also between the score and the degree of posterior urethrovesical angle (r = 0.797, P = 0.000; r = 0.62, P = 0.000, respectively). There was also a positive correlation between the severity score of incontinence and the increase in posterior urethrovesical angle during Valsalva's maneuver (r = 0.47, P = 0.02). & Conclusion: MRI is a non-invasive diagnostic method for the evaluation of bladder floor position, mobility of the bladder neck, and posterior urethrovesical angle in patients with stress urinary incontinence. It can play a major role in the postoperative follow up of stress urinary incontinence. MRI can also be used for the assessment of success in pubovaginal sling surgery. © TÜBİTAK.Item Dermatologic diseases and their effects on male sexual functions; [Dermatologische Erkrankungen und ihr Einfluss auf die männliche Sexual funktion](2010) Ermertcan A.T.; Temeltaş G.Chronic skin diseases may result in a variety of psychological problems, including distress, demoralization, poor self esteem, sleep disturbances, social phobia, anxiety, depression and obsessive-compulsive disorder. It is known that skin diseases may also cause sexual problems. Sexual activity remains important for most men throughout their adult lives and into old age. Impairment in their sexual experience can cause significant personal and interpersonal distress at any age. Sexual dysfunction in chronic systemic diseases has become a popular and important health concern in recent years. This subject is quite new in the specialty of dermatology. We explore the relationships between dermatologic diseases and male sexual dysfunction. © Blackwell Verlag GmbH, Berlin.Item Possible relations between oxidative damage and apoptosis in benign prostate hyperplasia and prostate cancer patients(IOS Press BV, 2014) Kosova F.; Temeltaş G.; Arı Z.; Lekili M.Cancer has been described as the twentieth century plague, and is a very common health problem. It has been reported that ROS and ROS products play a key role in cancer and that oxidative damage is effective in apoptosis initiation. In this study we aimed to evaluate the relationship between MDA (malondialdehyde), DNA damage (8-hydroxyguanine, 8-OH-dG), and caspase-3 in BHP and prostate cancer patients. Twenty male patients with prostate cancer and 20 male patients with benign prostate hyperplasia were included into this study. The MDA (nanomole), DNA damage (nanograms per millilitre), and caspase-3 (nanograms per millilitre) levels were measured in prostate cancer and benign prostate hyperplasia using Elisa kits (Millipore Corporation, Billerica, MA, USA). In the prostate cancer group, serum MDA (30.96± 9.25) and DNA damage (4.42±0.36) levels were significantly raised (p <0.05) when compared to the benign prostate hyperplasia group (24.05±8.06, 3.99±0.54). However, in the prostate cancer group, serum caspase-3 (2.36±0.82) levels were statistically significantly lowered (p <0.05) compared with the benign prostate hyperplasia group (3.15±1.04). We observed that altered prooxidant, DNA damage levels may lead to an increase in oxidative damage and may consequently play an important role in prostate carcinogenesis. These findings indicate that, although the triggering of these changes is unknown, changes in the levels of MDA, DNA damage, and caspase-3 in the blood are related to prostatic carcinoma development. In addition, it would be appropriate to conduct new studies with a large number of patients at different stages. © International Society of Oncology and BioMarkers (ISOBM) 2013.Item Assessment of proportion of hidden patients having symptoms of overactive bladder and why has it been hidden in female outpatients admitted to hospital(Korean Continence Society, 2016) Üçer O.; Demir Ö.; Zeren M.F.; Ceylan Y.; Çelen I.; Zümrütbaş A.E.; Temeltaş G.; Bozkurt O.; Günlüsoy B.; Çelik O.; Ekin G.; Mertoğlu O.Purpose: To determine the proportion of patients with undetected symptoms of overactive bladder by using the overactive bladder-validated 8 (OAB-V8) screening questionnaire and investigate these symptoms were undetected in female patients who were hospitalized. Methods: We invited 2,250 female patients hospitalized in the Aegean region of Turkey to answer a self-administered questionnaire. The questionnaire included questions on evidence of lower urinary tract symptoms (OAB-V8), relevant medical history, and demographic data. Patients with a total OAB-V8 score ≥ 8 were defined as having OAB symptoms. Results: The proportion of patients with OAB symptoms in this study was 40.6%. Nearly 57% of the patients with OAB symptoms had not been previously admitted to any hospital for lower urinary tract symptoms (LUTS). The two most common reasons why women with OAB symptoms did not admit themselves to a hospital because of LUTS were as follows: "I did not think I had a disease" and "The symptoms did not bother me," with a response rate of 74.7%. The mean OAB-V8 scores of the patients with these two responses were significantly lower than those of the other patients (P < 0.001). Conclusions: This is the first study to demonstrate a significant proportion of women with undetected OAB symptoms. The main reasons the women did not admit themselves to a hospital were their unawareness of the disease and because the LUTS were not bothersome. Public awareness programs on this disease may resolve this problem. © 2016 Korean Continence Society.Item The role of ultrasound guidance in pediatric caudal block(Saudi Arabian Armed Forces Hospital, 2016) Erbüyün K.; Açıkgöz B.; Ok G.; Yılmaz Ö.; Temeltaş G.; Tekin İ.; Tok D.Objectives: To compare the time interval of the procedure, possible complications, post-operative pain levels, additional analgesics, and nurse satisfaction in ultrasonography-guided and standard caudal block applications. Methods: This retrospective study was conducted in Celal Bayar University Hospital, Manisa, Turkey, between January and December 2014, included 78 pediatric patients. Caudal block was applied to 2 different groups; one with ultrasound guide, and the other using the standard method. Results: The time interval of the procedure was significantly shorter in the standard application group compared with ultrasound-guided group (p=0.020). Wong-Baker FACES Pain Rating Scale values obtained at the 90th minute was statistically lower in the standard application group compared with ultrasound-guided group (p=0.035). No statistically significant difference was found on the other parameters between the 2 groups. The shorter time interval of the procedure at standard application group should not be considered as a distinctive mark by the pediatric anesthesiologists, because this time difference was as short as seconds. Conclusion: Ultrasound guidance for caudal block applications would neither increase nor decrease the success of the treatment. However, ultrasound guidance should be needed in cases where the detection of sacral anatomy is difficult, especially by palpations. © 2016, Saudi Arabian Armed Forces Hospital. All rights reserved.Item The effect on the sensitivities of PSA and PSA-age volume score of IPSS and nocturia in predicting positive prostate biopsy findings(Pan African Urological Surgeons Association(PAUSA), 2017) Üçer O.; Müezzinoğlu T.; Çelen İ.; Temeltaş G.Objective The PSA-age volume (PSA-AV) score was calculated by multiplying the age and prostate volume and then dividing the total by the prebiopsy PSA level. The aim of this study was to evaluate the effect on the sensitivities of PSA and PSA-AV score of International Prostate Symptom Score (I-PSS) and nocturia in predicting positive prostate biopsy findings. Subjects and methods A total of 1302 biopsies data were divided into two groups according to presence/absence of nocturia. Of these biopsies, 452 biopsies data with I-PSS were also divided into three groups according to severity of I-PSS. The sensitivities, specificities, positive and negative predictive values of the PSA-AV and PSA in all the groups were calculated separately. Results Although the sensitivities of PSA and PSA-AV were similar in the patients with nocturia (94.1% and 95.8%, respectively), the sensitivity of PSA-AV (99.2%) was higher than PSA (91.8%) in the patients without nocturia. The sensitivities of PSA in mild, moderate and severe I-PSS group were found to be 100%, 92.9% and 95%, respectively (the sensitivities of PSA-AV were 100%, 94.4% and 88.2%, respectively). While severity of I-PSS was decreasing, although sensitivity of PSA-AV increased regularly, sensitivity of PSA was variable. Conclusions All our data shows that if we remove most of the factors which effect PSA such as age, prostate volume, prostatitis and BPH, we may increase the sensitivity of PSA for predicting positive prostate biopsy. Further PSA formulas contain of result of some tests (I-PSS, uroflowmetry or postvoiding residue urine) as well as age and prostate volume should increase the sensitivity and specificity of PSA for detecting prostate cancer. © 2016 Pan African Urological Surgeons’ AssociationItem Long term follow-up results of ablation treatment for patients with small renal mass(John Wiley and Sons Inc, 2021) Gümüş B.H.; Albaz A.C.; Düzgün F.; Üçer O.; Temeltaş G.; Müezzinoğlu T.; Tarhan S.Objective: The aim of this study is to evaluate the outcome of ablation therapy in our clinic for the treatment of patients with a small renal mass Materials and Methods: We retrospectively evaluated the technic and follow-up data of 30 patients with 36 tumours who underwent Radiofrequency Ablation (RFA) and Microwave Ablation (MWA) in our clinic. Demographic data, ablation type, tumour characteristics, peroperative and postoperative complications and treatment success of the patients were evaluated. Results: A total of 36 tumours who underwent ablation treatments, 23 were treated with RFA, 13 with MWA. The mean tumour size was 28.9 ± 6.92 mm in RFA and 29.3 ± 7.70 mm in MWA. The mean follow-up period was 49.6 ± 24.7 months in patients with RFA and mean follow-up was 16 ± 8.05 months in MWA treatments. The overall success in MWA administration was calculated as 76.9%, while the overall success in RFA was 80%. Conclusion: Long-term oncologic efficacy of RFA appears to be successful in the treatment of T1a renal carcinomas. Further studies can be conducted to elucidate the influence of MWA on long-term oncological outcomes. © 2021 John Wiley & Sons LtdItem Mediterranean Diet and Overactive Bladder(Korean Continence Society, 2022) Bozkurt Y.E.; Temeltaş G.; Müezzinoğlu T.; Üçer O.Purpose: The relationship between nutrition and overactive bladder (OAB) has yet to be elucidated. Therefore, this study investigated the relationship between the Mediterranean diet and OAB. Methods: The 14-item Mediterranean Diet Adherence Screener (MeDAS) and Overactive Bladder-Validated 8-question Screener (OAB-V8), validated in Turkish, were administered to 500 patients over the age of 18 who presented to outpatient clinics other than urology outpatient clinics. Of those patients, 174 with chronic diseases and urinary tract infections (based on urinalysis and a detailed medical history) were excluded. Therefore, 326 patients' data were analyzed. Results: There was a negative correlation between the MeDAS and OAB-V8 scores. High OAB-V8 scores were associated with obesity (body mass index ≥ 30 kg/m2), being single, and a low education level. Conclusions: Dietary patterns represent a broader perspective on food and nutrient consumption and may therefore be more predictive of disease risk. The Mediterranean type should be recommended in the first-line treatment of patients with OAB symptoms. It is easily possible to determine the compliance of patients with this diet by using the 14-item MeDAS. Copyright © 2022 Korean Continence SocietyItem Asymptomatic Giant Renal Calculi: Single-Session Percutaneous Nephrolithotomy—Images(Springer, 2023) Bozkurt Y.E.; Temeltaş G.; Üçer O.; Müezzinoğlu T.In a 55-year-old woman patient with a body mass index of 27 kg/m2, a giant staghorn kidney stone (10 × 6.4 × 8 cm) was detected in the right kidney on computed tomography, then the patient was treated with a single-session percutaneous nephrolithotomy, and there were no complications afterwards. © 2022, Association of Surgeons of India.