Browsing by Author "Tok A.C."

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    Plasma selenium levels in celiac disease patients on a gluten -free diet; [Glutensiz diyet alan çölyak hastası çocuklarda serum selenyum düzeyleri]
    (Galenos Yayincilik,, 2012) Ünal F.; Umman C.; Tok A.C.; Semizel E.; Ecevit C.O.; Özdemir S.; Taneli F.; Kasirga E.
    Introduction: Celiac disease (CD) is a gluten-induced enteropathy that results in malabsorption of nutrients such as selenium. A high incidence of malignancy in CD has been previously reported. Selenium is known to have a protective role against cancer. This study aimed to investigate whether there is an effect on serum selenium levels in children with CD on a gluten-free diet. Materials and Methods: Serum levels of selenium were studied in 17 children (mean age 5.64±3.30 years) with CD and 20 age-and gender-matched healthy children. CD was diagnosed according to ESPGHAN criteria. All the patients were clinically well and had been on gluten-free diets for 11.11±1.98 (mean±SE) months. All patients were fully consistent with the diet. The concentration of selenium was determined by a periodically validated atomic absorption spectrometer (Perkin Elmer AAS 700 system). Wet ashing procedure was used for all samples and controls. Results: In CD group one child's (5.8%), and in control group three children's (%15) serum selenium levels were found under normal limits. There was no statistically significant difference between serum selenium levels and the duration of gluten free diet (p>0.05). There was no statistically significant difference in serum selenium levels between celiac patients (124.19±12.31 μg/L) and control group (92.47±12.06 μg/L), (p>0.05). Discussion: It can be concluded that, normal levels of serum selenium in children with CD can be achieved with fully compatible gluten-free diet and a balanced diet which supplies daily selenium requirement. © The Journal of Current Pediatrics, published by Galenos Publishing.