Browsing by Author "Turan F."

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    A whole genome screen for linkage in Turkish multiple sclerosis
    (Elsevier, 2003) Eraksoy M.; Kurtuncu M.; Akman-Demir G.; Kilinc M.; Gedizlioglu M.; Mirza M.; Anlar Ö.; Kutlu C.; Demirkiran M.; Idrisoglu H.A.; Compston A.; Sawcer S.; Tombul T.; Asker Ö.; Balkan S.; Seçkin D.; Aydin H.; Akman-Demir G.; Kiyat A.; Yapici Z.; Epçeliden T.; Çe P.; Goldenberg E.; Gültiken B.; Güvenç A.; Işik N.; Seleker T.; Idiman E.; Özakbaş S.; Irkeç C.; Nazlier B.; Forta H.; Seleker F.; Güner K.; Karabudak R.; Kilinç M.; Komsuoǧlu S.; Efendi H.; Mert M.; Mirza M.; Erdoǧan F.; Müngen B.; Bulut S.; Özer F.; Yayla V.; Petek-Balci B.; Saǧduyu A.; Sarica Y.; Demirkiran M.; Selçuki D.; Mavioǧlu H.; Siva A.; Altintaş A.; Saip S.; Sütlaş N.; Kuşçu Yandim D.; Tireli H.; Özalp K.; Türkoǧlu R.; Örken C.; Özmanoǧlu M.; Velioǧlu S.; Özdemir G.; Gücüyener D.; Özkan S.; Tunali G.; Turan F.; Utku U.; Turgut N.; Ümit S.; Us Ö.; Ince Günal D.; Ütkür Y.; Aluçlu U.; Yavaşoǧlu Ö.; Yücemen N.; Yücesan C.; Zadikoǧlu A.; Zorlu Y.
    Factors exerting recessive effects on susceptibility to complex traits are expected to be over-represented in communities having a higher frequency of consanguineous marriage. Multiple sclerosis, a typical complex trait, is relatively common in Turkey where cultural factors also determine a high rate of consanguineous marriage. Previous genetic studies of multiple sclerosis in Turkey have been confined to the search for associations with candidate genes. In order to exploit the special genetic features of the Turkish population, we performed a whole genome screen for linkage in 43 Turkish multiplex families employing 392 microsatellite markers. Two genomic regions where maximum lod score (MLS) values were suggestive of linkage were identified (chromosomes 13q and 18q23) along with a further 14 regions of potential linkage. Parametric analysis of these data using a recessive model, appropriate for populations with a high frequency of consanguinity, increased the LOD scores in four regions. © 2003 Elsevier B.V. All rights reserved.
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    Towards better understanding of structural, physical and radiation attenuation properties of the granites in Aegean region of Turkey: İzmir and Kütahya Provinces
    (Institute of Physics, 2022) Deliormanll A.M.; Deliormanll A.H.; Turan F.; Issa S.A.M.; Almisned G.; Tekin H.O.
    In this study, physical, chemical, structural and radiation attenuation properties of some granite samples collected from Kütahya-Simav and İzmir (Bergama and Karaburun) were investigated. The true particle density of the studied granite samples was in the range of 2.65 g cm-3 to 2.72 g cm-3 and the median particle diameter was between ∼12 μm and 41 μm. According to the structural examination results obtained from the study, the chemical compositions of the extracted granite samples varied by area. While SiO2 was the dominating component in certain locations, it was replaced by Fe2O3 in another. This condition also had a direct effect on the densities of the granite samples extracted. At the conclusion of the study, it was found that the predominant factor affecting the radiation shielding characteristics of granites was the quantity of Fe2O3 in the composition, with the greatest gamma-ray shielding qualities supplied by samples 4 and 5, which had the highest Fe2O3 ratio. Our results indicate that sample 5 and the previously studied Capao Bonita sample had comparable half value layer values at low, medium, and high gamma ray levels. It may be concluded that Izmir granites are a more attractive option to granite for usage as radiation shielding building materials, owing to their high Fe2O3 concentration, and may be a feasible alternative to less desirable concrete materials for shielding applications. © 2022 IOP Publishing Ltd.