Browsing by Author "Uzuner, N"

Now showing 1 - 9 of 9
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    Landau-Kleffner syndrome
    Sayit, E; Dirik, E; Durak, H; Uzuner, N; Anal, Ö; Çevik, NT
    Landau-Kleffner syndrome (LKS) is a rare childhood disorder characterized by acquired aphasia with seizures and electroencephalogram (EEG) abnormalities. Tc-99m-HMPAO SPECT was performed in three right handed children with LKS. A relative decrease in perfusion was found in the left temporal cortex of all three patients and also in the left frontoparietal cortex of one patient with hyperkinetic behavior. Degree of regional cerebral perfusion impairment did not correlate with the severity of clinical and EEG abnormalities. Asymmetrical temporoparietal perfusion appears characteristic of LKS. SPECT findings in LKS were evaluated as useful in elucidating the pathogenic features of the disorder in the brain.
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    Successful Use of Inhaled Steroids For the Management of Radiation Pneumonitis in an Infant: Case Repot
    Uysal, KM; Uzuner, N; Çetingöz, R; Özgüven, AA; Babayigit, A; Ölmez, D; Günes, D; Olgun, N
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    The Utility of Childhood Asthma Control Test and its Relationship with Control Measures and with the Decisions Made by Asthma Specialist
    Sekerel, E; Keskin, O; Uzuner, N; Yazicioglu, M; Kilic, M; Artac, H; Ozmen, S; Can, D; Zeyrek, D; Cokugras, H; Soyer, O; Sapan, N; Aydogan, M; Kuyucu, S; Inal, A; Gurkan, F; Orhan, F; Yilmaz, O; Boz, AB; Tahan, F; Cevit, O
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    The reliability and validity of the Turkish version of a childhood asthma control test
    Soyer, OU; Keskin, O; Uzuner, N; Yazicioglu, M; Kilic, M; Artac, H; Ozmen, S; Can, D; Zeyrek, D; Cokugras, H; Sapan, N; Aydogan, M; Kuyucu, S; Inal, A; Gurkan, F; Orhan, F; Yilmaz, O; Boz, AB; Tahan, F; Cevit, O; Sekerel, B
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    Characteristics and Prognosis of Childhood Atopic Dermatitis: A Multicenter Study in Turkey
    Yuksel, H; Can, D; Reisli, I; Uzuner, N; Orhan, F; Cevit, O; Tahan, F; Canitez, Y; Kuyucu, S; Aysen, BB; Akcay, A; Yilmaz, O
    Background: Childhood atopic dermatitis (AD) is classically accepted as initial finding of atopic march; however, non-atopic cases do not follow this course. The aim of this study was to determine the characteristics and prognosis of AD in childhood in Turkey. Methods: The study included 531 children with AD that presented to pediatric allergy departments in 11 different regions of Turkey. Age at diagnosis, total serum and inhalant-specific immunoglobulin E (IgE) levels and allergen skin prick test results were recorded retrospectively. Clinical characteristics like additional allergic diseases at presentation or during follow-up were recorded as well as duration of follow-up. Results: Mean age at diagnosis was 37.8 +/- 36.2 months. Mean IgE level was 318.3 +/- 677.8 IU/ml (median 100 IU/ml). Skin prick tests yielded positive results in 47% of children. At presentation, 31.6% of children reported additional allergic disease, while 11.7% developed allergic disease during follow-up. Among all, 46.6% had additional allergic disease at any point. IgE levels were significantly higher in children with additional allergic diseases (p = 0.001). Allergen skin prick test positivity and family history of allergic diseases increased the risk of additional allergic diseases significantly (OR = 3.90, 95% CI = 2.3-6.6 and OR = 1.89, 95% CI = 1.3-2.8, respectively). Conclusions: Allergic sensitization is not present in all cases of AD. Coexistence of additional allergic diseases is not as high as expected but more common in children who have been demonstrated to have atopic sensitization with high IgE levels and allergen skin prick test positivity. Copyright (C) 2010 S. Karger AG, Basel
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    Characteristics and prognosis of childhood atopic dermatitis: a multi-center study in Turkey
    Yuksel, H; Can, D; Reisli, I; Uzuner, N; Orhan, F; Cevit, O; Tahan, F; Canitez, Y; Kuyucu, S; Boz, AB; Akcay, A; Yilmaz, O
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    (Un)Awareness of Allergy
    Kalpaklioglu, AF; Kalkan, IK; Akcay, A; Reisli, I; Can, D; Uzuner, N; Yuksel, H; Kirmaz, C; Gulen, F; Ediger, D
    Background: Allergy is associated with considerable morbidity. Objective: The aim of this multicenter study was to provide insight into allergy knowledge and perceptions among the population. Methods: During the World Allergy Day, several allergy clinics conducted public meetings to encourage the awareness of and education in allergy. At the beginning, participants filled out a questionnaire to assess their knowledge about what is allergy and to determine by whom those symptoms are cared. Results: A total of 256 participants (187 women/69 men, mean age, 31.2 +/- 12.5 years) completed the survey. Of the 202 participants with symptoms, 58.9% had physician-diagnosed allergic disease. Among the 19 symptoms evaluated, 56.5% of the symptoms were recognized as related with allergy, and this increased in compliance with education level (r = +0.427; P < 0.001) but not with diagnosed allergy (P = 0.34). Sneezing was the most common symptom thought to be related with allergy-related symptom (77.5%), whereas loss of smell was the least one (37.9%). Participants were more likely to be cared by an allergologist (72.9%) followed by other specialties, when experiencing allergy. Conclusions: Increasing the awareness for allergic symptoms is the key not only for the diagnosis but also for the optimal treatment. Therefore, education is an important component of prevention and control of allergic diseases.
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    Validity and reliability of the Turkish Migraine Disability Assessment (MIDAS) questionnaire
    Ertas, M; Siva, A; Dalkara, T; Uzuner, N; Dora, B; Inan, L; Idiman, F; Sarica, Y; Selçuki, D; Sirin, H; Oguzhanoglu, A; Irkeç, C; Özmenoglu, M; Özbenli, T; Öztürk, M; Saip, S; Neyal, M; Zarifoglu, M
    Objectives.-The aim of this study is to assess the comprehensibility, internal consistency, patient-physician reliability, test-retest reliability, and validity of Turkish version of Migraine Disability Assessment (MIDAS) questionnaire in patients with headache. Background.-MIDAS questionnaire has been developed by Stewart et al and shown to be reliable and valid to determine the degree of disability caused by migraine. Design and Methods.-This study was designed as a national multicenter study to demonstrate the reliability and validity of Turkish version of MIDAS questionnaire. Patients applying to 17 Neurology Clinics in Turkey were evaluated at the baseline (visit 1), week 4 (visit 2), and week 12 (visit 3) visits in terms of disease severity and comprehensibility, internal consistency, test-retest reliability, and validity of MIDAS. Since the severity of the disease has been found to change significantly at visit 2 compared to visit 1, test-retest reliability was assessed using the MIDAS scores of a subgroup of patients whose disease severity remained unchanged (up to +/- 3 days difference in the number of days with headache between visits 1 and 2). Results.-A total of 306 patients (86.2% female, mean age: 35.0 +/- 9.8 years) were enrolled into the study. A total of 65.7%, 77.5%, 82.0% of patients reported that they had fully understood the MIDAS questionnaire in visits 1, 2, and 3, respectively. A highly positive correlation was found between physician and patient and the applied total MIDAS scores in all three visits (Spearman correlation coefficients were R = 0.87, 0.83, and 0.90, respectively, P <.001). Internal consistency of MIDAS was assessed using Cronbach's and was found at acceptable (>0.7) or excellent (>0.8) levels in both patient and physician applied MIDAS scores, respectively. Total MIDAS score showed good test-retest reliability (R = 0.68). Both the number of days with headache and the total MIDAS scores were positively correlated at all visits with correlation coefficients between 0.47 and 0.63. There was also a moderate degree of correlation (R = 0.54) between the total MIDAS score at week 12 and the number of days with headache at visit 2 + visit 3, which quantify headache-related disability over a 3-month period similar to MIDAS questionnaire. Conclusion.-These findings demonstrated that the Turkish translation is equivalent to the English version of MIDAS in terms of internal consistency, test-retest reliability, and validity. Physicians can reliably use the Turkish translation of the MIDAS questionnaire in defining the severity of illness and its treatment strategy when applied as a self-administered report by migraine patients themselves.
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    The reliability and validity of Turkish version of Childhood Asthma Control Test
    Sekerel, BE; Soyer, OU; Keskin, O; Uzuner, N; Yazicioglu, M; Kiliç, M; Artaç, H; Ozmen, S; Can, D; Zeyrek, D; Cokugras, H; Canitez, Y; Aydogan, M; Kuyucu, S; Inal, A; Gurkan, F; Orhan, F; Yilmaz, O; Boz, AB; Tahan, F; Cevit, O
    Introduction The reliability and validity of Turkish version of Childhood Asthma Control Test (C-ACT). Purpose The management of asthma is an important as well as difficult issue of physician's daily practice particularly in busy clinical settings. C-ACT was created to identify asthma control levels in children aged 4-11 years. Our aim was to evaluate the reliability, validity and responsiveness of C-ACT in a Turkish sample of children with asthma. Method In this multicenter study, 368 children were enrolled. C-ACT was completed every month by parents and patients who were evaluated in 3 visits within 2 month intervals. At each visit, physicians interpret the control level and decided for the treatment step as established in GINA guidelines. Results The internal consistency reliability of the Turkish version of C-ACT (C-ACT1 to C-ACT5) was found to be 0.82, 0.83, 0.82, 0.82 and 0.80, respectively (reliability statistics, Cronbach's alpha). Test-retest reliability was 0.71. There was significant correlation between C-ACT and physician's assessment of asthma control at visit 1 (r = 0.65, P < 0.001). Conclusions Turkish version of C-ACT is an accurate and reliable tool to evaluate asthma control in children aged 4-11 years. Its widespread use may facilitate appropriate assessment of asthma control and may lead to decrease the number of uncontrolled patients.