Browsing by Author "Varol S.R."

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    Effects of eccentric exercise-induced delayed onset muscle soreness on endoplasmic reticulum stress-related markers; [Eksantrik egzersize bagli gecikmis kas agrisinin endoplazmik retikulum stresle iliskili belirteçler üzerindeki etkileri]
    (De Gruyter Open Ltd, 2021) Dogru Y.; Varol S.R.; Nalcakan G.R.; Akyuz M.; Tas M.; Ulman C.
    Short Communications: Apelin, pentraxin3 (PTX3), and interleukin6 (IL6) parameters are known as inflammation markers and found to be related to endoplasmic reticulum (ER) stress. The aimof the studywas to investigate the effect of eccentric exercise-induced delayed onset muscle soreness (DOMS) on ER stress-related markers in young athletes. Objectives and Methods: ER stress and DOMS-related blood markers, maximal strength level, and rate of perceived exertion using the visual analog scale (VAS) were assessed before, immediately after, 24, 48, and 72 h after the muscle damage protocol. Results: IL6 peaked 24 h after while creatine kinase and lactate dehydrogenase enzyme levels reached their peaks at 72 h after the protocol. The level of apelin continued to increase throughout the four measurements, and PTX3 peaked at 24 h, and then declined to the levels before the protocol but the differences were not significant. The significant decrease in the strength and the significant increase in VAS continued 48 h after the protocol. Conclusion: ER is activated and ER stress occurred, due to increases in IL6, PTX3 and apelin levels after the test protocol concluded that a single vigorous eccentric exercise should be avoided in harmful effect on health as parallel with Physical Activity Guidelines Open Access. 2020 Yeliz Dogru et al. © 2021 De Gruyter. All rights reserved.
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    Comparison of sprint interval and continuous endurance training on oxidative stress and antioxidant adaptations in young healthy adults
    (Gdansk University of Physical Education and Sport, 2021) Nalcakan G.R.; Onur E.; Oran A.; Varol S.R.
    Background: Different intensities of exercise induce varying levels of reactive oxygen species, causing oxidative stress. However, regular physical training enhances the antioxidant system and protects tissues by oxidative stress. This study aimed to investigate the difference in markers between time-efficient low-volume high intensity interval (sprint interval training: SIT) and traditional high-volume low-intensity methods (continuous endurance training: CET) regarding oxidative stress and antioxidant levels. Material and methods: Fifteen male volunteers were divided into two groups according to their VO2max levels. The SIT program consisted of 4–6 Wingate all-out sprints with a 4.5 min recovery, while CET consisted of 30–50 min cycling at 60% VO2max for seven weeks. Total oxidant status (TOS), total antioxidant status (TAS), plasma malondialdehyde (MDA) and glutathione peroxidase (GSH-Px) levels were examined in pre and post-intervention. Results: Increases in GSH-Px (30% vs. 55%), TOS (33% vs. 18%) and a significant decrease in MDA (8.6%, p<0.003; 6.8%, p<0.016) in CET and SIT were observed, respectively. By contrast, TAS decreased (62%) after CET and increased (17%) after SIT. No significant differences in these parameters were reported after the training period between SIT and CET groups. Conclusions: SIT was suggested as a safe exercise model to improve general health and the performance of traditional CET. © Gdansk University of Physical Education and Sport, Poland.