Browsing by Author "Yavuz I.H."

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    Internalized stigma in pediatric psoriasis: A comparative multicenter study
    (Korean Dermatological Association, 2020) Alpsoy E.; Polat M.; Yavuz I.H.; Kartal P.; Balci D.D.; Karadag A.S.; Bilgic A.; Arca E.; Karaman B.F.; Emre S.; Adisen E.; Sendur N.; Bilgic O.; Yazici A.C.; Yalcin B.; Koca R.; Gunduz K.; Borlu M.M.; Ergun T.; Dursun P.; Bilgili S.G.; Adanir A.S.; Gulekon A.; Yagcioglu G.; Yilmaz E.; Kavuzlu U.; Senol Y.
    Background: Internalized stigma, adoption of negative attitudes and stereotypes of the society regarding persons' illness, has not been studied previously in pediatric psoriasis patients. Objective: We aimed to investigate the internalized stigma in pediatric psoriasis patients and to determine differences according to factors affecting internalized stigma compared to adult psoriasis patients. Methods: This multicenter, cross-sectional, comparative study included 125 pediatric (55 female, 70 male; mean age±standard deviation [SD], 14.59±2.87 years) and 1,235 adult psoriasis patients (577 female, 658 male; mean age±SD, 43.3±13.7 years). Psoriasis Internalized Stigma Scale (PISS), Dermatology Life Quality Index (DLQI), Perceived Health Status (PHS), and the General Health Questionnaire (GHQ)-12 were the scales used in the study. Results: The mean PISS was 58.48±14.9 in pediatric group. When PISS subscales of groups were compared, the pediatric group had significantly higher stigma resistance (p=0.01) whereas adult group had higher scores of alienation (p=0.01) and stereotype endorsement (p=0.04). There was a strong correlation between mean values of PISS and DLQI (r=0.423, p=0.001). High internalized stigma scores had no relation to either the severity or localization of disease in pediatric group. However, poor PHS (p=0.007) and low-income levels (p=0.03) in both groups, and body mass index (r=0.181, p=0.04) in the pediatric group were related to high PISS scores. Conclusion: Internalized stigma in pediatric patients is as high as adults and is related to poor quality of life, general health, and psychological illnesses. Unlike adults, internalized stigma was mainly determined by psoriasis per se, rather than disease severity or involvement of visible body parts, genitalia or folds. Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology.
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    Clinical Features and Natural Course of Hidradenitis Suppurativa in Turkey: A Multicenter Study
    (S. Karger AG, 2024) Alpsoy E.; Fettahlloglu Karaman B.; Demirseren D.D.; Clnar S.L.; Kacar N.; Türel Ermertcan A.; Bulbul Baskan E.; Ucmak D.; Mammadli K.; Klllnc F.; Yazici S.; Temiz S.A.; Özkök Akbulut T.; Ataseven A.; Şikar Aktürk A.; Sarlcaoǧlu H.; Türkmen M.; Gülbaşaran F.; Engin B.; Kaya Özden H.; Durmaz K.; Güler Özden M.; Özdemir H.; Çevirgen Cemil B.; Sarlkaya Solak S.; Bilgili S.G.; Yavuz I.H.; Özaydln Yavuz G.; Güven M.; Polat Ekinci A.; Atcl T.; Didar Balci D.; Oztürk A.; Klvanç Altunay I.; Özkur E.; Ugurer E.; Karadag A.S.; Kalkan G.; Klllc S.; Erdoǧan B.; Yayli S.; Baykal Selçuk L.; Dönmez L.; Bilgic A.
    Introduction: The natural history, the progression of a disease process in an individual over time, has not yet been fully elucidated in hidradenitis suppurativa (HS). In this large multicenter study, we aimed to investigate the natural history of HS and its gender differences. Methods: This cross-sectional study included 827 patients. The chronological order of the clinical manifestations for each patient was recorded retrospectively. Sociodemographic characteristics, triggering factors, clinical, treatment, and prognostic featureswere also evaluated. Results: The mean age of disease onset was significantly younger in women than in men (22.42 ± 9.28 vs. 27.06 ± 20.56, p < 0.001) and those with a family history (p < 0.0001). The mean disease duration was 91.17 ± 83.64 months. The most common symptom was purulent discharge (81%). The mean duration of abscess was shorter in women than in men (3.11 ± 2.65 vs. 3.75 ± 3.75, p = 0.01). The axilla was the most common onset area followed by the inguinal and gluteal regions. The disease ran a more severe course in men. Abscess/inflammatory nodule was defined in the last 6 months in 88.6% of the patients; however, the first 5 years of the disease were the most active disease period in 67.5% of the patients. Multivariate analysis revealed being male, older age, family history, involvement of the axillary, inguinal, and perianal regions independently associated with HS severity. While antibiotic use was the most important factor in improving the disease symptoms, stress was themost common aggravating factor. Biological therapy in men, laser epilation and pregnancy in women were significant alleviating factors, whereas weight gain was a more common aggravating factor for women. Conclusion: HS shows a relentlessly progressive course with inflammatory attacks, but the first years of the disease are the most active period. This study confirms that environmental and hormonal factors may play an important role in the disease course, probably with other endogenous or exogenous factors. © 2024 S. Karger AG, Basel.