Browsing by Author "Yener, G"

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    Validation and Reliability of The Frontal Assesment Battery (FAB) in Turkish
    Tunçay, N; Kayserili, G; Eser, E; Zorlu, Y; Akdede, BB; Yener, G
    Scientific background: The Frontal Assessment Battery (FAB) test is a short test aiming to assess frontal lobe functions. It is composed of 6 items that give a total possible score between 0 and 18. The items include assessing the ability to find similarities between objects, categorical verbal fluency, resistance to interference, a simple go-no go paradigm, and peripheral autonomy. A higher score denotes better performance. Purpose: To determine the validity and reliability of the psychometric properties of the Turkish version of the Frontal Assessment Battery Method: The Turkish FAB was evaluated in 94 cases with diverse neuro-psychological conditions and in 92 healthy controls. Translation and back-translations of Turkish were done. In addition to FAB, the respondents completed a Standardized Mini Mental assessment scale, Stroop scale and a brief sociodemographic questionnaire. Reliability analysis involved test-retest reliability and internal consistency (alpha), whereas validity analysis involved factor analysis, convergent validity approach, known groups and criterion validity tests, and sensitivity analysis. Parametric and non-parametric correlations, T tests and ANOVA were used during these analyses. Findings: The alpha value was sufficient (alpha=0.73) for FAB but the alpha value decreased when the 6th item was deleted, indicating a problem with this item, as also confirmed by the factor solution. The fewer the years of education, the worse the FAB scale scores (p<0.001); men scored higher than women in a few items (mental flexibility, sensitivity to interference, and inhibitory control). The relationship between FAB and the Standardized Mini Mental Test (0.765, p<0.000) and Stroop scores indicated.
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    Measurements of radon content in soil gas and in the thermal waters in Western Turkey
    Erees, FS; Yener, G; Salk, M; Özbal, Ö
    Radon is a radioactive gas which makes the primary contribution to the natural radiation to which people are exposed. For that reason, great importance is attributed to the determination of radon concentration levels in water, indoor air, soil gas and outdoors. In the present work radon content measurements in soil gas, as well as gamma dose rate surveys of the surface area were realized at 112 stations in Western Turkey. The scintillation detector of EDA Instrument Inc. was used for the radon measurements in soil gas. The radon concentration in 40 thermal water samples in same region was also studied. Radon concentration was measured by the collector chamber method. Radon distribution was found to be related with the tectonic lines and high heat flow zones in the region. (c) 2005 Elsevier Ltd. All rights reserved.
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    Basal and activational 99Tcm-HMPAO brain SPECT in Alzheimer's disease
    Sayit, E; Yener, G; Çapa, G; Ertay, T; Keskin, B; Fadiloglu, S; Durak, H
    Early diagnosis in Alzheimer's disease (AD) is important for the administration of new treatments. The purpose of this study was to differentiate mildly/moderately demented AD patients from normal controls by means of activational brain SPECT, and to investigate the correlation between regional cerebral blood flow and dementia severity. Activational brain SPECT was performed 1 week after basal brain SPECT in 12 mild/moderate AD patients according to NINCDS-ADRDA criteria (mean age 69 +/- 7 years) and in seven healthy, age-matched, volunteer controls (mean age 65+/-9 years). Ln order to activate the parietal cortex, patients were asked to subtract serial 5's from 100, 2 min before and after the intravenous administration of 925 MBq technetium-99m labelled D,L-hexamethyl-propylene amine oxime (Tc-99(m)-HMPAO). Using a three-headed gamma camera equipped with high resolution collimators, 128 images of 35 s duration in a 64 x 64 matrix were obtained over 360 degrees. Region to whole brain ratios (R/WB) were calculated in three consecutive transaxial slices 2 pixels thick above the orbitomeatal line, and the activation percentage was calculated. No statistical difference was detected between AD patients and normal controls for parietal cortex activation. The correlation coefficient between the Mini-Mental State Examination (MMSE) scoring and the activation percentage was 0.475 in normal controls and 0.175 in AD patients for the left anterior parietal cortex, and 0.353 in normal controls and 0.146 in AD patients for the right anterior parietal cortex. In a visual evaluation of parietal cortex activation, 50% of AD patients were able to activate the parietal cortex, whereas 86% of the normal controls could do so. Ln our current study, the subtraction of serial 5's was not regarded as a promising task. Further studies are needed to clarify the importance of such tasks in the differential diagnosis of mild/moderate AD patients from normal elderly. ((C) 2000 Lippincott Williams & Wilkins).
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    Radon concentrations in thermal waters related to seismic events along faults in the Denizli Basin, Western Turkey
    Erees, FS; Aytas, S; Sac, MM; Yener, G; Salk, M
    The aim of this study is to investigate the relationship between the earthquakes and radon concentrations in thermal waters along faults in the Denizli Basin, an area in Turkey known for its high seismic activity and thermal waters. This area was chosen because it exhibits active crustal movements combined with seismicity and there are numerous outflow thermal waters and gas outputs. In addition, this region has the type of tectonic activity where graben groups and faults take place. Measurements of radon levels and of some chemical and physical characteristics of thermal waters were made at seven sampling stations in the region. Radon concentrations were measured by a ZnS(Ag) scintillation counter in a collector chamber. The activity levels varied between 0.67 and 25.90 kBq m(-3) during the period of May-December 2000. In the evaluation of the results, the seismic data reported by Bogazici University Kandilli Observatory and Earthquake Research Institute, Seismological Laboratory were used. The increases observed in radon concentration at two stations were probably related to the earthquakes that took place in the region during the study period. (c) 2006 Elsevier Ltd. All rights reserved.