Browsing by Author "Yigit E."

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    Clinical and psychosocial factors affecting treatment adherence in children with rheumatic heart disease
    (NLM (Medline), 2022) Alkan F.; Yigit E.; Sapmaz S.Y.; Coskun S.
    INTRODUCTION: The present study aimed to investigate the outcomes of psychiatric symptoms and family functions on treatment adherence in children, in addition to sociodemographic characteristics and clinical factors related to the disease. MATERIAL AND METHOD: The research sample consisted of 43 children who were followed up with rheumatic heart disease diagnosis during the study. Clinical features were obtained from the patient files. The family assessment device evaluating family functioning and the strengths and difficulties questionnaire scale to screen emotional and behavioural problems in children were used. RESULTS: Considering the regularity of treatment in our patients, there were 31 (72%) patients adherent to secondary prophylaxis regularly, 7 (6.9%) patients were partially adherent, and 5 (11.6%) patients non-adherent. Patients were divided into treatment adherent (Group 1) and non-adherent (Group 2). There was no statistically significant impact on treatment adherence whether the patients receive enough information, lifestyle, fear of developing adverse effects, fear of addiction, lack of health insurance, difficulties in reaching the drug or hospital. However, the fear of syringes on treatment adherence had an effect statistically significantly (p = 0.047). Forgetting to get a prescription and/or take the drug when the time comes was statistically higher in the non-adherent group (p = 0.009). There was no statistically significant effect of psychosocial factors on treatment adherence between groups. DISCUSSION: Providing an effective active recall system, involving primary care workers, providing training on the disease and its management, and a comprehensive pain management programme can improve the process, especially for cases where secondary prophylaxis is missed.
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    Effect of various cross-sections on the flexural behaviour of composite beams
    (Sakarya University, 2023) Yigit E.; Saklakoglu N.
    This study investigated the influence of various cross-sections on the flexural properties of composite beams. Within the first stage of the paper, a finite element model represented the standard three-point bending test of a composite beam was developed. The model was correlated by mesh dependency analysis and a three-point bending test. After model correlation was completed, composite beam models with 6 cross-sections were generated as CAD data and imported to the correlated finite element model. As a result of the studies, it has been determined that the F profile is the most unstable profile compared to other sections, and the D profile is the most durable profile. © 2020, Historical and Geographical Institute of Rio Grande do Sul. All rights reserved.
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    Nasal effects of environmental tobacco smoke exposure in children with allergic rhinitis
    (W.B. Saunders Ltd, 2025) Yigit E.; Yuksel H.; Ulman C.; Yilmaz O.
    Objectives: Tobacco smoke exposure is associated with inflammatory changes in the respiratory system including nasal mucosa. Our aim was to demonstrate nasal mucosal inflammation such as neutrophilic activation and epithelial permeability in patients with allergic rhinitis with exposure to environmental tobacco smoke (ETS) and reveal its effect on allergic rhinitis symptoms. Methods: We enrolled 204 subjects with allergic rhinitis to this cross-sectional study. Sociodemographic and AR clinical characteristics were recorded. Urinary cotinine levels >50 ng/ml were defined as exposure to secondhand tobacco smoke. Club cell 16 (CC16) and myeloperoxidase (MPO) levels were measured in the nasal lavage fluid. Levels of these biomarkers and clinical severity were compared between ETS exposed and non-exposed children with AR. Results: Among 204 children enrolled, 53 (26 %) had ETS exposure. Mean age of the ETS exposed group was significantly higher than the unexposed group (12.1 ± 3.5 and 10.7 ± 3.6 years respectively, (p = 0.02). Similarly, T5SS score was significantly higher in ETS exposure group (9.3 vs 8.3, p = 0.03) but this significance was lost when corrected for age. Age and T5SS were inversely correlated with MPO levels (r = −0,24, p < 0.001 and r = −0,14, p = 0.04). Nasal lavage CC-16 and MPO levels were not found to be significantly different among subjects with and without ETS exposure (p = 0.13 and p = 0.26 respectively). Conclusion: Our results demonstrated that ETS exposure is associated with more persistent AR in children. However, it is not related to severity or nasal lavage MPO or CC16 levels. Rhinitis symptoms beyond allergen period suggests isolated smoke exposure effect. © 2024