Browsing by Author "Yildirim, E"

Now showing 1 - 6 of 6
  • No Thumbnail Available
    Item
    The effect of COVID-19 on patients recieving omalizumab treatment
    Sayaca, N; Cansiz, KA; Yildirim, E; Öztnrk, B; Kirmaz, C
    Background and aim. - Although exposure during drug administration and susceptibility to coronavirus disease-19 (COVID-19) infection secondary to immunomodulatory effects constitute potential risks for patients with chronic spontaneous urticaria (CSU) or asthma on omalizumab (OMZ), there is a risk of loss of response following discontinuation of OMZ. There are few studies describing the clinical course of COVID-19 in patients receiving OMZ. Materials and methods. - A total of 103 patients on OMZ were included in the study between February 2021 and January 2022. Results. - Fourteen (13.6%) of the patients participating in the study had SARS-CoV-2 infection, of whom 3 (21.4%) required hospitalization and 11 (78.6%) were treated in an outpatient clinic. During the pandemic, 17 (16.5%) of the patients interrupted their OMZ treatment. Patients on OMZ for six months or less had a lower rate of interruption (2.5%) than those on OMZ for more than 6 months (25.4%). Patients interrupted treatment for the following reasons: 3 (17.6%) had COVID-19, 10 (58.9%) did not attend the hospital visit due to concern about contamination with SARS-CoV-2, and 4 (23.5%) thought that OMZ treatment would facilitate contamination with SARS-CoV-2. After interrupting OMZ, 3 (25%) female patients and 5 (100%) male patients presented no worsening of their symptoms. Three (13%) of the patients on OMZ for asthma and 11 (13.8%) of those on the drug for urticaria had COVID-19 infection. Patients presenting CSU and severe asthma are completely different, with different potential consequences of OMZ interruption. Nine (52.9%) patients had aggravated symptoms following interruption of OMZ treatment. Three of them described worsening of asthma symptoms and a need to increment their maintenance therapy due to asthma exacerbation after nearly three weeks of interruption, and 6 of them had hives and pruritus as urticaria exacerbation nearly four weeks after interruption of OMZ. The asthma patients did not stop their other treatments, including inhaled corticosteroids. Conclusion. - Use of OMZ does not increase the risk of SARS-CoV-2 infection, COVID-19-related pneumonia, or COVID-19-related hospitalization. We advise patients not to interrupt OMZ treatment during the COVID-19 pandemic unless advised to do so by their doctors, and we recommend that they receive instruction concerning self-administration of OMZ to avoid visiting hospitals in the event of a pandemic. (c) 2023 Elsevier Masson SAS. All rights reserved.
  • No Thumbnail Available
    Item
    The percentage of hesitation and factors associated with acceptance or refusal for COVID-19 vaccine: Does training about vaccines by allergist affect personal decision?
    Sayaca, N; Cansiz, KA; Yildirim, E; Öztürk, B; Kirmaz, C
    Background and aim. - As the impact of coronavirus disease (COVID)-19 arises worldwide, the effect of vaccines is protecting its importance. The aim of this study was to investigate the vaccination perspectives of patients and learn how many patients were persuaded to get vaccinated with the effect of the education provided by allergists. Materials and methods. - A cross-sectional study was carried out among 200 adult patients in the outpatient clinic between February 2021 and January 2022. Patients filled out the anti-vaccination scale form and a questionnaire form developed by allergists. The training about COVID-19 vaccines has been given to the patients who did not consider getting vaccinated. The patients were called by phone and questioned whether they have been vaccinated or not, after 22 weeks. Results. - Out of 200 patients participants, 60.5% were considering getting vaccinated. Patients who did not consider getting vaccinated comprised 45.7% of women and 31% of men. While 52.4% of primary school graduates considered getting vaccinated, 75% of high school graduates and 60.8% of higher education graduates were considering getting vaccinated. Major reasons for rejecting vaccination were concerns about side effects and allergy. While the majority of women (47.2%) who did not want to get vaccinated were concerned about vaccine side effects, the majority of men (34.6%) did not want to get vaccinated because they did not trust the efficacy of the vaccine. Vaccination rates have been increased with the training we provided to our patients who did not consider getting the vaccine. 76 patients could be reached by phone and 81.6% of them were vaccinated, and 18.4% were not. Conclusion. - The vaccination rates of allergy patients who did not consider getting vaccinated were increased with the information provided by allergists. So, the allergists should give more attention for giving information and increasing the vaccination rates of covid-19. (c) 2022 Elsevier Masson SAS. All rights reserved.
  • No Thumbnail Available
    Item
    Assessments of thermal performance of hybrid and mono nanofluid U-tube solar collector system
    Yildirim, E; Yurddas, A
    Solar energy systems are of great importance for water heating, where we spend most of the energy. U -tube solar collectors have a very important place in water heating among solar energy systems. Compensation of the intense energy used for water heating by this type of environmentally friendly solar energy system, will reduce CO2 and SO2 emissions for a cleaner nature. Therefore; the thermal perfor-mance of a U-tube complete system from evacuated tube solar collector (ETSC) systems was assessed. The heat transfer capability of the system, which contains 10 U-tubes, has been examined by considering the fact that it has different work fluids and different heat fluxes and flow rates. The finite volume method is used for this analysis. The model has been verified by many experimental and numerical studies. In the system under consideration has been used 10 vacuum U-tubes inclined at 30 degrees, and water and nanofluid (SiO2-Cu) which were used as working fluid in the manifolds connected to these tubes. Nanoparticles modeled in the work fluid are considered as hybrid and mono at different volume frac-tions. The thermal and hydrodynamic behaviors of the system have been examined by taking into ac-count the Boussinesq approach, and the system outlet temperatures have been calculated. As a result of analyzes and comparisons made, it has been seen that the use of nanofluid improves the thermal capability of the system under consideration. It has been determined that this improvement reaches up to 15% compared to water. The thermal effects of using SiO2 nanoparticles, which are lighter than Cu nanoparticles, were observed in terms of the precipitation problem encountered in many systems when using hybrid nanofluids. Thus, instead of using more Cu nanoparticles in volume, using smaller amounts together with SiO2 nanoparticles as a hybrid both eliminates the problem of precipitation and improves the heat capability of the work fluid. (c) 2021 Elsevier Ltd. All rights reserved.
  • No Thumbnail Available
    Item
    Attitude and Practice Toward Use of Cigarettes and Electronic Cigarettes Among Pregnant Women: A Questionnaire-Based Survey
    Yildirim, E; Duru, S; Sevim, T; Topçu, F; Gemicioglu, B; Özmen, I; Ocakli, B; Tuncay, E; Altinöz, H; Akpak, YK; Çelik, P; Varol, Y; Polat, G; Özkan, S; Dursunoglu, N; Kiliç, D; Gülhan, PY; Diken, ÖE; Çetinkaya, PD; Yorgancioglu, A; Selçuk, NT; Yildiz, F; Atacag, T; Niksarlioglu, EY; Uzaslan, E; Köktürk, N
    OBJECTIVE: This study aimed to evaluate attitude and practice toward use of regular tobacco cigarettes and electronic cigarettes among pregnant women. MATERIAL AND METHODS: A total of 1123 pregnant women participated on a voluntary basis in this questionnaire survey. Maternal characteristics, cigarette consumption parameters, and personal opinions regarding the adverse effects of smoking during pregnancy were evaluated. RESULTS: Active smokers composed 12.4% (9.4%: regular tobacco cigarettes, 3.0%: electronic cigarettes) of the study population. Smoking during the current pregnancy, particularly via regular tobacco cigarettes, was more likely for women with smoking during previous pregnancies (56.0% vs. 7.8%, P <.001), previous history of low birth weight infant delivery (16.1% vs. 8.6%, P =.013), premature delivery (16.7% vs. 7.0%, P <.001), and stillbirth (22.8% vs. 11.7%, P =.002). The presence versus absence of smoking during pregnancy was associated with a lower likelihood of being a housewife (70.5% vs. 80.5%, P =.010) and a higher likelihood of having an actively smoking mother (25.9% vs. 11.2%, P <.001) or partner (65.7% vs. 46.9%, P <.001). Regular tobacco cigarette users considered electronic cigarettes to have a higher risk of adverse impacts (11.1% vs. 2.9%, P =.012), while electronic cigarette users considered regular cigarettes to have a higher risk of nicotine exposure (55.9% vs. 13.0%, P <.001). CONCLUSION: Our findings indicate being employed, having an actively smoking mother or partner, as well as smoking in previous pregnancies, to be the risk factors for increased likelihood of smoking during pregnancy.
  • No Thumbnail Available
    Item
    Relationship between functional status and fatigue after COVID-19 infection: a multicenter study from Turkiye
    Candemir, I; Ergün, P; Kaymaz, D; Sahin, ME; Özmen, I; Yildirim, E; Dilektasli, AG; Yigitliler, B; Odabas, A; Kizilirmak, D; Sari, S; Korkmaz, C; Tasci, C; Arslan, Y; Savci, S; Kahraman, B; Tanriverdi, A; Sevinç, C; Saglam, M; Ince, DI; Yagli, NV; Kütükcü, E; Durmaz, D; Durutürk, N; Ulubay, G; Kiliç, L; Çaglayan, B; Moray, A; Olcay, SS; Özkaya, G
    Background/aim: Symptoms of COVID-19 may persist for months. One of the persistent symptoms of COVID-19 is fatigue, which reduces functional status. The relationship between fatigue, functional status, and various other factors has received little attention, which this study aims to address.. Materials and methods: Patients with COVID-19 infection were included in this multicenter cross-sectional study. Age, sex, body mass index (BMI), marital status, smoking status, presence and duration of chronic disease, comorbidity index, regular exercise habits, time since COVID-19 diagnosis, hospitalization status, length of hospital stay, intubation status, home oxygen therapy after discharge, participation in a pulmonary rehabilitation program, presence of dyspnea, presence of cough, presence of sputum, and modified Medical Research Council, Post-COVID Functional Status (PCFS), Fatigue Severity Scale (FSS), and EQ-5D-5L Questionnaire scores were recorded. Results: We enrolled 1095 patients, including 603 (55%) men and 492 (45%) women with a mean age of 50 +/- 14 years. The most common chronic lung disease was COPD (11%) and 266 (29%) patients had nonpulmonary disease. The median time elapsed since COVID-19 diagnosis was 5 months; the hospitalization rate was 47%. The median PCFS grade was 1 (0-4) and the median FSS score was 4.4 (1-7). The PCFS and FSS were positively correlated (r = 0.49, p < 0.01; OR: 1.88, 95% CI: 1.68-2.10). Both functional status and fatigue were associated with quality of life, which was lower in older patients, those with higher BMI, those with systemic disease, those not exercising regularly, and those with more severe COVID-19 infection (defined by dyspnea, pneumonia as indicated by computed tomography, hospitalization, length of stay, ICU admission, intubation, and the need for home oxygen after discharge). Conclusion: Fatigue may cause poorer functional status regardless of the time since COVID-19 diagnosis. In this study, patients with FSS scores of >4.78 showed moderate to severe functional limitations. It is important to address modifiable patient risk factors and reduce the severity of COVID-19 infection.
  • No Thumbnail Available
    Item
    The Relationship Between Functional Status and Fatigue After COVID-19 Infection
    Candemir, IÇ; Ergun, P; Kaymaz, D; Özmen,; Yildirim, E; Dilektasli, AG; Yigitler, B; Kizilirmak, D; Sari, S; Korkmaz, C; Tasçi, C; Arslan, Y; Savci, S; Kahraman, B; Tanriverdi, A; Sevinç, C; Saglam, M; Ince, DI; Yagli, NV; Kütükçü, E; Durmaz, D; Durutürk, N; Ulubay, G; Kiliç, L; Çaglar, B; Moray, A; Olcay, SS