Browsing by Author "Yildirim S.A."

Now showing 1 - 4 of 4
  • No Thumbnail Available
    Item
    Changes in quantitative ultrasound in preterm and term infants during the first year of life
    (2011) Tansug N.; Yildirim S.A.; Canda E.; Özalp D.; Yilmaz O.; Taneli F.; Ersoy B.
    Since most of in utero bone mass accretion occurs during the third trimester and postnatal need for bone nutrients is increased, preterm infants have an increased risk of low bone mass. Early identification of the risk is of crucial importance. Quantitative ultrasound, which is a relatively inexpensive, portable, noninvasive, and radiation-free method, gives information about bone density, cortical thickness, elasticity and microarchitecture. The aim of this study was to obtain quantitative ultrasound measurements of tibial speed of sound of preterm and term infants and to assess clinical factors associated with these measurements during the first year of life. Seventy-eight preterm and 48 term infants were enrolled in this study. Measurements were made on the 10th day of life in both groups, and were repeated on the 2nd, 6th and 12th months for preterm infants and on the12th month for the term infants. Speed of sound on preterm infants was significantly decreased on the 2nd month but significantly increased on the 12th month (P = 0.00). Comparing speed of sound of term and preterm infants, 10th day measurements were significantly different (P = 0.00), but there was not any significant difference between the 12th month values (P = 0.26). There was not any relation between biochemical parameters and speed of sound. The technique has potential clinical value for assessment of bone status. Further studies with long term follow up are needed to evaluate the value of quantitative ultrasound with other bone markers to predict the risk of fracture. © 2010 Elsevier Ireland Ltd. All rights reserved.
  • No Thumbnail Available
    Item
    Diagnostic yield of upper gastrointestinal endoscopy in the evaluation of iron deficiency anemia in older children and adolescents
    (2011) Gulen H.; Kasirga E.; Yildirim S.A.; Kader S.; Sahin G.; Ayhan S.
    Iron deficiency anemia (IDA) is frequent in childhood. Inadequate nutrition and gastrointestinal malabsorption are the frequent causes of IDA in children. But reduced iron absorption and insidious blood loss from the gastrointestinal tract has been identified as the most frequent causes of IDA in older children and adolescents. Therefore the authors evaluated the frequency and etiologies of the upper gastrointestinal system pathologies causing IDA in older pediatric population. Patients with known hematological or chronic diseases, heavy menstrual flow, and obvious blood loss were excluded from the study. Forty-four children between the ages of 9.5 and 17.5 years and diagnosed with IDA were enrolled. They underwent upper gastrointestinal endoscopy and biopsy from esophagus, stomach, and duodenum. Mean age and hemoglobin (Hb) levels of study group (32 boys, and 12 girls) were 14.6 ± 2.0 years and 7.9 ± 1.8 g/dL, respectively. Only 1 patient had a positive serology testing with anti-tissue transglutaminase and small bowel biopsy correlating with celiac disease. Endoscopy revealed abnormal findings in 25 (56.8%) patients (21 endoscopic antral gastritis, 2 active duodenal ulcers, and 2 duodenal polyps). Helicobacter pylori (HP) infection was identified by using antral histopathological evaluation in 19 of 44 children (43.2%). In 2 of duodenal samples, one patient had celiac disease, and the other one was diagnosed as giardiasis. In conclusion, there are different etiologies resulting in IDA in older children and adolescents. When older children and adolescents are found to have iron deficiency, HP infection and other gastrointestinal pathologies should be ruled out before iron deficiency treatment. © 2011 Informa Healthcare USA, Inc.
  • No Thumbnail Available
    Item
    EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI): Study protocol for a multicentre, observational trial
    (BMJ Publishing Group, 2021) Weiss R.; Saadat-Gilani K.; Kerschke L.; Wempe C.; Meersch M.; Zarbock A.; Makhloufi H.; Cherak A.; Ghanem L.L.; Gouaglia Z.; Guadouri D.N.; Hama F.N.; Kara M.; Saadi O.; Sakhraoui R.; Bourou F.; Cherifi A.; Sadaoui R.G.; Ouyahia A.; Ouahab I.; Bouaoud S.; Abdoun M.; Tidjane A.; Tabeti B.; Boudjenan-Serradj N.; Rivera C.J.P.; Cabrer P.; Corso J.; García J.P.; Idarraga S.; Montoya C.; Figueroa R.; Aldana E.; Torrado M.A.; Peng K.; Ma Z.-M.; Yang Y.-F.; Zhu Y.-J.; Sklienka P.; Frelich M.; Jarkulis V.; Sevcik P.; Vodicka V.; Elbahnasawy M.G.; Elsalhawy S.; Motawea S.; Othman Z.; Sahma M.; Nafea A.M.; Ahmed N.; Attia D.A.; Emara M.M.; Bonna M.M.; Gabr M.A.; Tarbay A.I.; Abdehaleem I.A.; Mohamed E.E.; Eldeeb A.M.; Abbas A.M.; Magdy J.A.; Hamed Z.H.; Osman H.M.E.; Abbas M.S.; Joannes-Boyau O.; Barraud N.; Berthelot C.; Camus T.; Dahmi A.; Defaye M.; Derville S.; El-Boustani Y.; Deloge E.; Jacob H.; Monziols S.; Priem F.; Robin J.-J.; Legros V.; Floch T.; Muccio S.; Geneve C.; Legouge M.L.; Mauny S.T.; Mfam W.; Pascot L.; Aveline C.; Chartier M.; Duteurtre B.; Gautier J.F.; Cousin A.L.; Vautier P.; Nadaud J.; Begel N.; Chekirine C.-A.; Derlon V.; Grein E.; Lehair M.-A.; Magazzeni L.; Magazzeni P.; Potter C.; Roth C.; Voivret F.; Rimmelé T.; Cerro V.; Suria S.; Elmawieh J.; Stoclin A.; Cirenei C.; Andrieu G.; Couloumy S.; Falcone J.; Fajardy M.; Gagneuil A.; Girardet E.; Mazereeuw A.; Ponsonnard S.; Egreteau P.-Y.; Bertel M.; Bocher S.; Carn V.; Guen L.L.; Loup G.L.; Lefevre M.; Ichai C.; Diop A.; Jean-Michel V.; Devlieger S.; Duthoit J.; El Kadiri M.; Léger M.; Cassisa V.; Lasocki S.; Masson C.; Rineau E.; Verrier P.; Coquerel A.; Montravers P.; Atchade E.; Rochon C.-E.; Delerue C.; Quentin V.; Latry V.; Queixalos N.; Cottenceau V.; Braun T.; Bouzoubaa S.; Christ B.; Geiger A.; Gomille J.; Kieffer V.; Mangeant S.; Prochilo C.; Schmitt C.; Skwirba S.; Grand H.; Boury F.; Mayeur N.; Pasquie M.; Garçon P.; Bruckert V.; Arnould V.; Bonciu M.; Chapelle T.; Facchino L.; Fagot-Gandet F.; Iachim A.; Mannu E.; Perus O.; Plattier R.; Rozier R.; Pradel G.; Boudinaud M.; Hausermann M.-H.; Nguyen M.H.; Ramorasata A.; Barreau A.; Boivin A.-H.; Ravry C.; Mottard N.; Beuvelot J.; Bossion F.P.; Desebbe O.; Dörr C.; von Groote T.C.; Küllmar M.; Massoth C.; Ziemann S.; Grüßer L.; Kowark A.; Wittig P.; Brandenburger T.; Dimski T.; Döhmen N.; Huthmann L.; Kaierle D.; Pelletier C.; Schleß M.; Hohn A.; Cleophas S.; Haunhorst S.; Jansen M.; Schmitt A.; Soisch J.; Sturm K.; Rosenberger P.; Bendig A.; Flohr L.; Häberle H.; Hofmann P.; Kuhle J.; Leser N.M.; Pfister K.; Prohaska S.; Sennholz F.; Stetz L.; Weber K.; Stehr S.; Klaus S.; Sadlo M.; Boschin M.; Sengelhoff C.; Göbel U.M.; Haaker J.G.; Göttker C.-K.; Gründel M.; Heringlake M.; Baumgärtel R.; Berggren A.; Gülzow M.; Muras L.; Paarmann H.; Thal S.; Bentley A.; El-Masri D.; Sebastiani A.; Arnaoutoglou E.; Ntalouka M.; Stratigopoulou P.; Analytis A.; Mavrommatis E.; Tzimas P.; Karakosta A.; Pantazi D.; Dimakopoulou A.; Dimitropoulou K.; Ioannidis O.; Jalaawiy H.; Anwar A.; Hashim H.T.; Aldawoody H.I.R.; Cortegiani A.; Catalisano G.; Ingoglia G.; Ippolito M.; De Rosa S.; Cattin L.; Bianchin A.; Barone M.; Paternoster G.; Cutuli S.L.; Russo A.; Sollazzi L.; Cascarano L.; Antonelli M.; Aceto P.; Romanò B.; Spadaro S.; Tripodi V.F.; Rossi M.; Scappatura R.; Vadalà M.C.; Fiume D.; Strano M.T.; Oddo G.; Santorsola C.; Hussain B.A.; Alnaser A.R.; Ghassan A.H.; Hasanein K.; Theab M.; Shin S.; Jung S.; Lee K.; Jung S.M.; Baek J.; Elhadi M.K.; Aldressi W.W.O.; Abuzeid I.; Albaraesi M.; Aldressi S.; Khalel W.; Abdulwahed E.; Abujrad A.A.A.; Almaghrabi A.; Alteleeb M.; Alshareea E.A.A.; Biala M.I.; Deeknah A.; Gheddim D.A.; Ghmagh R.; Ikhrays N.S.A.A.; Sinan M.; Soula E.; Bahroun S.G.; Derwish K.; Mohamed A.M.; Younes E.S.; Al Islam Benjouira R.; Aliwa M.; Altashani N.A.; Alteb M.O.; Msherghi A.; Alagelli F.; Albarouni S.; Albishti A.; Aljamal S.; Alsori M.; Ekhuja T.; Elzwai S.; Ghula M.; Mustafa T.; Tuwaib A.; Zriba H.; Agilla H.M.; Rafanomezantsoa T.A.; Podesta A.M.C.; Bonnici D.M.; Pirotta T.; López G.A.G.; Mijovska M.M.; Davitkovska T.; Gavrilovska A.; Lukikj S.; Vesova M.; Zafirova D.; Amro S.; Hajjaj B.N.F.; Alkhazendar M.; Barakat Y.; Elejla S.A.; Elhissi A.; Khader A.; Salem A.; de Freitas Regufe R.; de Oliveira Eloy A.F.; Perdigão L.M.N.C.; Grigoriev E.; Ivkin A.; Kornelyuk R.; Yaroustovsky M.; Abramyan M.; Komardina E.; Lesteva N.; Aybazova M.; Kumykova E.; Lesina S.; Rybakov G.; Shestov A.; Barmou A.A.A.; Ahmed B.L.A.; Eliyas A.M.; Emadeldin Y.; Kaserer A.; Castellucci C.; Rössler J.; Akbas S.; Petrun A.M.; Gregorcic I.; Sok V.; Cicak R.; Bárcena E.; Guisado A.; Wi I.; Melchor J.R.; Becerra-Bolaños Á.; Cabrera-Doreste S.; Domínguez-Arbelo A.; Delgado-Alonso M.C.; Muiño-Palomar V.; Rodríguez-Pérez A.; Estévez J.M.; Munoz M.B.C.; Matas J.M.; Palao S.P.; Quirós M.D.M.; Teslev A.C.; Argilaga M.; Campos M.; Bainac A.; Batalla A.; Alvarez M.G.; Giné M.; Herránz G.; Hinojal I.; Ejea M.L.; de la Rosa Ruiz N.; Abasolo M.G.; Acuna C.R.H.; Zaranton I.I.; Mendigurenmurua A.; Sanz M.J.M.; de la Fuente E.O.; Vaquero M.P.P.; Iglesias A.S.; Mieres A.U.; Urrestizala A.U.; Ferreira L.; Lobato F.; Sevilla M.A.; Erazo A.; Miró P.; Sabaté S.; Vernetta D.; Perez A.A.; Pagola M.A.; Paulis B.C.; del Val Peciña E.; Odriozola A.G.; Aizpurua A.L.; Piquer O.P.; Garcia P.P.; Rezola P.O.; Lopez A.O.; de la Calle Gil I.; Casado R.N.; Adamove P.; Domenge R.B.; Blasco F.M.B.; Villamizar A.A.R.; Llaneras M.A.P.; García-Sánchez J.I.; Téllez L.F.; Zamorano S.G.; Herreros N.G.; Esteve A.R.; Rodríguez P.M.; Trigo I.G.; Alcaraz A.; Jiménez A.L.; Rubio I.; García N.; Callejas R.; Toha A.M.C.; Claros E.; Cobeta P.; Crespo P.; Dorado T.; Elías E.; Felices J.; Gil D.; Gómez M.; Mané N.; Martín M.; Martínez A.; Pereira L.; Samaranch A.B.N.; Serrano A.; Tiscar C.; VillaHoz J.; Menéndez P.G.; Cardona E.; Conesa A.; Estepa V.; Galán P.; Espí L.L.; Aldeán Y.L.; Manrique S.; Ariza V.M.; Villa L.V.; Suliman E.S.M.A.; Hamid H.; Ibrahim A.M.; Saeed M.M.; Mukadder O.S.; Altun D.; Canbolat N.; Dinçer M.B.; Seyhan T.Ö.; Yildirim S.A.; Iyigün M.; Yapici D.; Özdemir L.; Sagun A.; Boztug N.; Cetintas Y.; Dinc B.; Gündüz E.; Ünlügenç H.; Tunay D.L.; Karakaya D.; Dost B.; Komurcu O.; Akcil E.F.; Dilmen Ö.K.; Tunali Y.; Ok G.; Alsina E.T.; Hakli Ö.; Polat C.; Turgut N.; Kizilcik N.; Köner Ö.; Sen Ö.; Aydin N.; Basaran B.; Bingul E.S.; Gürkan Y.; Darcin K.; Ugur S.; Saracoglu K.T.; Demir A.; Aysegül Ö.; Balci E.; Girgin B.; Guler A.; Karadeniz Ü.; Özaslan N.; Hülya Y.Ö.; Ozcan N.; Postaci A.; Sahap M.; Salman N.; Sagir Ö.; Atik B.; Bicakcioglu M.; Demir H.F.; Fatih U.; Kocaoglu N.; Toprak H.I.; Aslan D.D.; Colak Y.Z.; Ozcan M.S.; Yilmaz M.; Karaca U.; Sahin S.H.; Karka Ö.E.; Senoglu G.D.; Karadag S.E.; Alkis N.; Baytas V.; Akdogan A.; Besir A.; Erturk E.; Kutanis D.; Saylan S.; Tugcugil E.; Ayvat P.; Günaydin B.; Büyükgebiz B.M.; Boran O.F.; Calisir F.; Orak Y.; Balkan B.K.; Büyükcoban S.; Gökel E.; Günenc S.F.; Özbilgin S.; Göre S.; Akesen S.; Cansabuncu S.; Momot N.; Panchenko A.; Pittet J.-F.; Rutledge K.
    Introduction More than 300 million surgical procedures are performed each year. Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term outcomes. However, there is a large variation in the incidence of reported AKI rates. The establishment of an accurate epidemiology of surgery-associated AKI is important for healthcare policy, quality initiatives, clinical trials, as well as for improving guidelines. The objective of the Epidemiology of Surgery-associated Acute Kidney Injury (EPIS-AKI) trial is to prospectively evaluate the epidemiology of AKI after major surgery using the latest Kidney Disease: Improving Global Outcomes (KDIGO) consensus definition of AKI. Methods and analysis EPIS-AKI is an international prospective, observational, multicentre cohort study including 10 000 patients undergoing major surgery who are subsequently admitted to the ICU or a similar high dependency unit. The primary endpoint is the incidence of AKI within 72 hours after surgery according to the KDIGO criteria. Secondary endpoints include use of renal replacement therapy (RRT), mortality during ICU and hospital stay, length of ICU and hospital stay and major adverse kidney events (combined endpoint consisting of persistent renal dysfunction, RRT and mortality) at day 90. Further, we will evaluate preoperative and intraoperative risk factors affecting the incidence of postoperative AKI. In an add-on analysis, we will assess urinary biomarkers for early detection of AKI. Ethics and dissemination EPIS-AKI has been approved by the leading Ethics Committee of the Medical Council North Rhine-Westphalia, of the Westphalian Wilhelms-University Münster and the corresponding Ethics Committee at each participating site. Results will be disseminated widely and published in peer-reviewed journals, presented at conferences and used to design further AKI-related trials. Trial registration number NCT04165369. ©
  • No Thumbnail Available
    Item
    Acute kidney disease beyond day 7 after major surgery: a secondary analysis of the EPIS-AKI trial
    (Springer Science and Business Media Deutschland GmbH, 2024) Meersch M.; Weiss R.; Strauß C.; Albert F.; Booke H.; Forni L.; Pittet J.; Kellum J.A.; Rosner M.; Mehta R.; Bellomo R.; Rosenberger P.; Zarbock A.; Makhloufi H.; Sakhraoui R.; Ouyahia A.; Rais M.; Kouicem A.T.; Derwish K.; Abdoun M.; Ouahab I.; Bouaoud S.; Tidjane A.; Pérez Rivera C.J.; García J.P.; Peng K.; Ji F.-H.; Ma Z.-M.; Elbahnasawy M.G.; Elsalhawy S.; Nafea A.M.; Osman N.A.; Emara M.M.; Bonna M.M.; Abdehaleem I.A.; Abbas A.M.; Abbas M.S.; Esmaeil H.M.; Joannes-Boyau O.; Legros V.; Floch T.; Muccio S.; Menage-Innocenti L.; Brochet B.; Leclercq-Rouget M.; Geneve C.; Mocarquer B.V.; Aveline C.; Vautier P.; Nadaud J.; Rimmelé T.; Cerro V.; Suria S.; Elmawieh J.; El-Jawiche R.; Cirenei C.; Lebuffe G.; Ponsonnard S.; Egreteau P.-Y.; Ichai C.; Jean-Michel V.; Léger M.; Lasocki S.; Masson C.; Rineau E.; Cassisa V.; Verrier P.; Atchade E.; Rochon C.-E.; Quentin V.; Queixalos N.; Braun T.; Grand H.; Mayeur N.; Pasquie M.; Garçon P.; Bruckert V.; Pradel G.; Ramorasata A.; Ravry C.; Mottard N.; von Groote T.; Dörr C.; Küllmar M.; Massoth C.; Motekallemi A.; Saadat-Gilani K.; Kerschke L.; Storck M.; Varghese J.; Wempe C.; Grüßer L.; Kowark A.; Brandenburger T.; Hohn A.; Häberle H.; Hofmann P.; Kuhle J.; Calov S.; Bernard A.M.; Mirakaj V.; Weber K.; Pfister K.; Stetz L.; Müller S.D.; Klaus S.; Sadlo M.; Sengelhoff C.; Stenger C.-K.; Göbel U.; Heringlake M.; Arnaoutoglou E.; Stratigopoulou P.; Danai P.; Dimakopoulou A.; Menis A.-A.; Ioannidis O.; Jalaawiy H.; Anwar A.; Hashim H.T.; Rasheed Aldawoody H.I.; Cortegiani A.; Ippolito M.; Marino C.; Presti G.; Fricano D.C.; De Rosa S.; Bianchin A.; Paternoster G.; Fasciano U.; Cutuli S.L.; Savino S.; Enrico B.; Marco P.; Alberto V.C.; Tripodi V.F.; Fiume D.; Iuorio A.; Santorsola C.; Abu-Hussein B.; Hasanein K.; Shin S.; Baek J.; Kim S.; Elhadi M.; Aldressi W.; Abuzeid I.A.; Albaraesi M.N.; Moftah M.A.; Aldressi S.; Khalel W.; Abdulwahed E.; Ali Alshareea E.A.; Abujrad Reem Ghmagh A.A.A.; Biala M.I.; Benjouira R.A.I.; Aliwa M.; Msherghi A.; Tuwaib A.; Mustafa T.; Zriba H.; Agilla H.M.; Sadek Ben Hamida B.T.; Mohamed Otman R.H.; Mijovska M.M.; Podesta A.M.C.; Gasca López G.A.; Amro S.; de Freitas Regufe R.; Grigoryev E.; Ivkin A.; Balakhnin D.; Shukevich D.; Yaroustovsky M.; Barmou A.; Kaserer A.; Castellucci C.; Akbas S.; Petrun A.M.; Gregorcic I.; Sok V.; Links A.; Barreto E.B.; Melchor J.R.; Becerra-Bolaños Á.; Rodríguez-Pérez A.; Estévez J.M.; Matas J.M.; Palao S.P.; Álvarez M.G.; Albadalejo A.B.; González A.B.; Caro A.M.G.; Blanco I.H.; Fernandez D.T.; Perez G.H.; Ejea M.L.; de la Rosa Ruiz N.; Abasolo M.G.; Ferreira L.; Lobato F.; Sevilla M.A.; Erazo A.; Paulis B.C.; de la Calle Gil I.; Adamove P.; Blasco F.M.B.; García-Sánchez J.I.; Zamorano S.G.; Herreros N.G.; Callejas R.; Gómez M.E.; Candela-Toha A.M.; Claros-Llamas E.; Cobeta-Orduña P.; Crespo-Aliseda P.; Dorado-Díaz T.; Gómez-Rojo M.; Mané-Ruiz M.N.; González M.C.M.; Martínez-Pérez A.; Tiscar C.; Menéndez P.G.; Calvo V.E.; Espí L.L.; Aldeán Y.S.L.; Ariza V.M.; Vila L.V.; García-Miguel F.J.; Suliman E.S.M.; Ibrahim A.M.; Fadlalmola H.A.; Swed S.; Wu V.-C.; Orhan-Sungur M.; Altun D.; Canbolat N.; Dinçer M.B.; Yildirim S.A.; Iyigun M.; Yapıcı D.; Özdemir L.; Sagün A.; Boztug N.; Gündüz E.; Lafli-Tunay D.; Karakaya D.; Dost B.; Komurcu O.; Dilmen O.K.; Akcil E.F.; Tunali Y.; Ok G.; Tok-Alsina E.; Polat C.; Kızılcık N.; Şen Ö.; Darçın K.; Uğur S.; Gürkan Y.; Saracoglu K.T.; Yıldız-Koyuncu Ö.; Demir Z.A.; Postacı N.A.; Özgök A.; Karadeniz Ü.; Özay H.Y.; Balcı E.; Salman N.; Girgin B.; Sagir O.; Demir H.F.; Ugun F.; Toprak H.İ.; Özcan M.S.; Alkaya-Solmaz F.; Yilmaz M.; Karaca U.; Şahin S.H.; Erkoç S.K.; Alkış N.; Baytaş V.; Erturk E.; Saylan S.; Akdogan A.; Yeşil B.B.; Boran O.F.; Orak Y.; Çalişir F.; Büyükçoban S.; Kuvaki B.; Cansabuncu S.; Akesen S.; Gören S.; Yeniocak T.; Orman O.; Karka Ö.E.; Sahin T.; Momot N.; Panchenko A.; Rutledge K.
    Purpose: Acute kidney disease (AKD) is a significant health care burden worldwide. However, little is known about this complication after major surgery. Methods: We conducted an international prospective, observational, multi-center study among patients undergoing major surgery. The primary study endpoint was the incidence of AKD (defined as new onset of estimated glomerular filtration rate (eCFR) < 60 ml/min/1.73 m2 present on day 7 or later) among survivors. Secondary endpoints included the relationship between early postoperative acute kidney injury (AKI) (within 72 h after major surgery) and subsequent AKD, the identification of risk factors for AKD, and the rate of chronic kidney disease (CKD) progression in patients with pre-existing CKD. Results: We studied 9510 patients without pre-existing CKD. Of these, 940 (9.9%) developed AKD after 7 days of whom 34.1% experiencing an episode of early postoperative-AKI. Rates of AKD after 7 days significantly increased with the severity (19.1% Kidney Disease Improving Global Outcomes [KDIGO] 1, 24.5% KDIGO2, 34.3% KDIGO3; P < 0.001) and duration (15.5% transient vs 38.3% persistent AKI; P < 0.001) of early postoperative-AKI. Independent risk factors for AKD included early postoperative-AKI, exposure to perioperative nephrotoxic agents, and postoperative pneumonia. Early postoperative-AKI carried an independent odds ratio for AKD of 2.64 (95% confidence interval [CI] 2.21–3.15). Of 663 patients with pre-existing CKD, 42 (6.3%) had worsening CKD at day 90. In patients with CKD and an episode of early AKI, CKD progression occurred in 11.6%. Conclusion: One in ten major surgery patients developed AKD beyond 7 days after surgery, in most cases without an episode of early postoperative-AKI. However, early postoperative-AKI severity and duration were associated with an increased rate of AKD and early postoperative-AKI was strongly associated with AKD independent of all other potential risk factors. © The Author(s) 2024.