Browsing by Author "Yildiz, IE"

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    Consideration Whether Hepatitis B Exists in Children Whose Mothers Suffer from Chronic Hepatitis B and These Mothers in Gestational Age
    Yildiz, IE; Tosun, S; Sen, S; Altunal, LN; Ugurlu, K; Bahsi, A
    Objectives: Perinatal and intrauterine transmission of the hepatitis B virus (HBV) represents a major factor, leading to the development of chronic infection. This study aimed to explore the status of mothers and their children for hepatitis B (HB) infection during pregnancy and childhood, and whether active and passive immunoprophylaxis was administered to infants shortly after birth. Materials and Methods: We performed multicenter, retrospective research on voluntary hepatitis B surface antigen (HBsAg)-positive mothers admitted to infectious diseases polyclinics was performed. Mothers and their children were queried by a questionnaire about their HB infection status. Data from the electronic data recording system was scanned retrospectively. Results: Three hundred-one mothers and 616 children were included in the study. HBsAg was examined in 354 (57.4%) of pregnancies. Of 91 children with HBsAg positivity, 83 were not applied active and passive immunoprophylaxis after birth. Eight 276 babies received both immune prophylaxes after birth were then detected as HBsAg positive. On HBV examination, 148 children were found to encounter the HBV. HBsAg positivity rate was significantly higher in children born before 1997. Conclusion: The remarkable decrease in HBsAg positivity of children reveals the efficacy of national vaccination. By informing both healthcare workers and society, awareness about examining pregnants for HBsAg during pregnancy should be increased.
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    Are Soap, Paper Towel and Alcohol-based Disinfectants Easily Accessible in Intensive Care Units in Turkey?: Results of the Phokai Study
    Uyan, A; Durmus, G; Sezak, N; Özdemir, B; Kaygusuz, T; Öztoprak, N; Özdemir, K; Aksoy, F; Özgültekin, A; Koç, MM; Öncül, A; Çagan Aktas, S; Isik, B; Çelebi, G; Evik, G; Özger, S; Harman, R; Dindar Demiray, EK; Özkören Çalik, S; Alkan Çeviker, S; Yildiz, IE; Isik, ME; Senol, G; Sari, S; Dogan, M; Ugurlu, K; Arslan, M; Akgül, F; Koç, F; Kürekçi, Y; Çaglayan, D; Uçar, M; Gözüküçük, R; Elmaslar Mert, HT; Alay, H; Erdogan, H; Demirel, A; Dogan, N; Koçak, F; Güven, E; Ünsal, G; Sipahi, H; Yamazhan, T; Arda, B; Ulusoy, S; Sipahi, OR
    Introduction: Hand hygiene is one of the most effective infection control measures to prevent the spread of healthcare-associated infections (HCAI). Water, soap, paper towel and hand disinfectant must be available and adequate in terms of effective hand hygiene. The adequacy of hand hygiene products or keeping water-soap and paper towel is still a problem for many developing countries like Turkey. In this multicenter study, we analyzed the adequacy in number and availability of hand hygiene products. Materials and Methods: This study was performed in all intensive care units (ICUs) of 41 hospitals (27 tertiary-care educational, 10 state and four private hospitals) from 22 cities located in seven geographical regions of Turkey. We analyzed water, soap, paper towel and alcohol-based hand disinfectant adequacy on four different days, two of which were in summer during the vacation time (August, 27th and 31st 2016) and two in autumn (October, 12th and 15th 2016). Results: The total number of ICUs and intensive care beds in 41 participating centers were 214 and 2357, respectively. Overall, there was no soap in 3-11% of sinks and no paper towel in 10-18% of sinks while there was no alcohol-based hand disinfectant in 1-4.7% of hand disinfectant units on the observation days. When we compared the number of sinks with soap and/or paper towel on weekdays vs. weekends, there was no significant difference in summer. However, on autumn weekdays, the number of sinks with soap and paper towel was significantly lower on weekend days (p<0.0001, p<0.0001) while the number of hand disinfectant units with alcohol-based disinfectant was significantly higher (p<0.0001). Conclusion: There should be adequate and accessible hand hygiene materials for effective hand hygiene. In this study, we found that soap and paper towels were inadequate on the observation days in 3-11% and 10-18% of units, respectively. Attention should be paid on soap and paper towel supply at weekends as well.
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    Surgical Antimicrobial Prophylaxis Compliance in Turkey: Data from the Prospective, Observational, Multicenter Survey Including 7,978 Surgical Patients
    Ekinci, SÇ; Yenilmez, E; Öcal, GA; Sönmezer, MC; Tarakçi, A; Aygün, C; Akdag, D; Seyman, D; Asik, C; Zerdali, E; Karadag, FY; Kaya, S; Çelik, M; Çifci, S; Yildiz, IE; Çölkesen, F; Akgül, F; Aldemir,Ö; Bozdag, M; Özer, D; Hizmali, L; Ünlü, EC; Altunay, DG; Sahin, A; Ünlue, G; Gencalioglu, AE; Sahin, ST; Özdemir, Y; Ünlü, S; Singil, S; Altintas, J; Isik, SA; Gül,Ö; Tuna, N; Simsek, S; Özgüler, M; Kiliç, PE; Isik, ME; Karakus, A; Kiratli, K; Yardimci, AC; Volkan, S; Olçar, Y; Çakir, Y; Yilmaz, NÖ; Karaayvaz, S; Batirel, A; Duran, ZC; Rasa, HK; Köse, S
    Background: Surgical antimicrobial prophylaxis (SAP) is the peri-operative administration of antimicrobial agents. Compliance rates vary worldwide from 15% to 84.3%, with studies in Turkey not exceeding 35%. The aim of this multicenter study was to determine the rate of appropriate antibiotic class, timing, and duration as well as discharge prescriptions in Turkey. Thus, we aimed to determine the rate of full compliance with SAP procedures in our country Patients and Methods: This multicenter, prospective, observational, descriptive study was conducted in 47 hospitals from 28 provinces in seven different regions of Turkey. Patients over 18 years of age in all surgical units between June 6, 2022, and June 10, 2022, were included in the study. Results: Of the 7,978 patients included in the study, 332 were excluded from further analyses because of pre-existing infection, and SAP compliance analyses were performed on the remaining 7,646 cases. The antibiotic most commonly used for SAP was cefazolin (n = 4,701; 61.5%), followed by third-generation cephalosporins (n = 596; 7.8%). The most common time to start SAP was within 30 minutes before surgery (n = 2,252; 32.5%), followed by 30 to 60 minutes before surgery (n = 1,638; 23.6%). Surgical antimicrobial prophylaxis duration was <24 hours in 3,516 (50.7%) patients and prolonged until discharge in 1,505 (21.7%) patients. Finally, the actual proportion of patients compliant with SAP was 19% (n = 1,452) after omitting 4,458 (58.3%) patients who were prescribed oral antibiotic agents at discharge as part of a prolonged SAP. Conclusions: Surgical antimicrobial prophylaxis compliance rates are still very low in Turkey. Prolonged duration of SAP and especially high rate of antibiotic prescription at discharge are the main reasons for non-compliance with SAP.