Browsing by Author "Yildiz, S"
Now showing 1 - 14 of 14
Results Per Page
Sort Options
Item Investigation of Histopathological and Cytogenetic Effects of Heavy Metals Pollution on Cyprinus carpio (Linneaus, 1758) in the Golmarmara Lake, TurkeyGurcu, B; Yildiz, S; Koca, YBG; Koca, SConcentration of heavy metals were measured in the surface water, sediments and three different organs of Cyprinus carpi from the Golmarmara lake (Manisa, Turkey). Four sampling sites located at different parts of the lake were pre-defined. The accumulation of copper, zinc, cadmium, cobalt, lead, chromium, iron, mangane in gills, liver and muscle of C. carpi were determined. Also, histopathological changes in gill, liver and muscle tissue were examined at light microscopical level. The order of accumulation of heavy metals was found to be Zn>Pb>Fe>Co>Mn>Cr>Ni>Cti>Cd in water, Zn>Cr>Pb>Fe>Co>Mn>Ni>Cu>Cd in sediment, Zn>Cr>Pb>Ni>Cu>Fe>Co>Cd in muscle and Zn>Cr>Pb>Cd>Ni>Cu>Fe>Co in liver and Zn>Cr>Ni>Pb>Cu>Cd>Co>Fe in gills. As a result of histopathological examinations, a significant decrease in mean length of primary and secondary lamellae was observed. Cellular proliferation caused secondary lamellae fusion, ballooning degenerations of secondary lamellae as well as distribution of necrotic and clavate secondary lamellae. In the liver, altered staining, swollen and ruptured parenchymal cells reduce of glycogen in hepatocytes and vacuolar structure filled with cellular debris were seen. In muscle tissue, focal necrosis, cellular dissolution and a decline or loss of striatation in muscle fibres were found. The frequency of micronucleus formation did not show significant differences in fish samples caught from the Golmarmara lake.Item Acute effects of different warm-up methods on free kick performance in amputee soccer playersYildiz, S; Kayihan, G; Gelen, E; Çilli, M; Özkan, ABACKGROUND: There are studies documenting the detrimental effects of static stretching and useful effects of dynamic exercises. However, there is no study which has researched the acute effects of different warm-up exercises on free kick performances in amputee soccer. The purpose of this study was to compare the acute effects of static stretching and dynamic warm-up exercise on free kick performance in amputee soccer players. METHODS: Twelve amputee soccer players playing for the national team (mean age 28+7 years) were investigated in our study. This study was designed to determine the acute effects of 3 different warm-up (WU) methods static stretching (SS), dynamic exercises (DYN) and control (NS) on anaerobic performance (free kick speed performance) RESULTS: Although significant differences (P<0.001) were found for DYN and NS when the free kick speed levels of the soccer players were compared pre and post-test; no obvious difference (P>0.05) was found for SS. The data shows that there is a significant increase in free kick speed for DYN and NS according to pre and post-tests results. CONCLUSIONS: The results of this study suggest that it may be desirable for amputee soccer players to perform dynamic exercises before performing activities that require a high power output.Item Investigation of the effects of physico-chemical environmental conditions on population fluctuations of Notonecta viridis Delcourt, 1909 (Hemiptera: Notonectidae) in Van Lake by using Zero-inflated generalized Poisson regressionYesilova, A; Özgökçe, MS; Atlihan, R; Karaca, I; Özgökçe, F; Yildiz, S; Kaya, YIn ecological studies, it is a common situation occured that population density of species extremly increases or decreases in certain periods depending on many abiotic and biotic factors. Because of ecologial factors that cause high level fluctuation in population density, It is possible to get zero individual at samplings, and on the other hand, differences between maximum and minimum values obtained in different samplings intervals can be very high. Because this type of data based on counting does not show normal distribution, and shape of the distribution is skewed to the right because of the abundance of zero, using the Zero-inflated Poisson regression method (ZIGP) is required. This study was carried out to obtain information on effects of physico-chemical environmental conditions on population fluctuation of Notonecta viridis. Samplings were conducted with monthly periods along the coastal band of Van Lake in 2005-2006. Samples were taken from 20 sampling places where have three different characters as stream entrances, settlements and natural coastlines. Reults were analysed by using ZIGP regression model. According to results, Effect of sampling intervals and sampling stations on population densities of Notonecta viridis were important. On the other hand, HCO3 had negative effect on population densities in zero-inflated model while it had possitive effect on population densities in other two models. It was determined that Fe effected the species populations in the negative way in the mean regression model, and Cl and Mg effected it in possitive way in the overdispersion regression. In the result, it was deductived that Notonecta viridis was found excessive numbers or none in some sampling stations because of the pysico-chemical structures of water.Item Genotoxic and histopathological effects of water pollution on two fish species, Barbus capito pectoralis and Chondrostoma nasus in the Buyuk Menderes River, TurkeyKoca, S; Koca, YB; Yildiz, S; Gürcü, BThe genotoxic and histopathological effects of water pollution were investigated on two fish species caught from the Buyuk Menderes River and from its tributary, the Cine Stream. The Buyuk Menderes basin is an important agricultural area in Turkey. The levels of copper, zinc, cadmium, cobalt, and lead were measured at the surface of the water and in gills, liver, and muscle tissue of Chondrostoma nasus and Barbus capito pectoralis. In some tissues, the concentrations of some of these metals exceeded acceptable levels for human consumption. Zinc was found to be the most abundant metal in water and tissues. Maximal metal accumulation was observed in the liver. To detect the genotoxic potential of contaminants, the formation of micronucleus in erythrocytes was used as indicator of chromosomal damage. The frequency of micronucleus formation did not show significant differences between locations and controls in B. capito pectoralis caught from three locations and C. nasus from two locations. The histological changes included significant decreases of the mean lengths of primary and secondary lamellae. In gills epithelia, we observed cellular proliferation that developed Because of secondary lamellae fusion, ballooning degenerations, or club deformation of secondary lamellae and cystic structures in secondary lamellae. In the liver, the changes included swollen and ruptured parenchymal cells, loss of cord structure, vacuoles filled with cellular debris, focal necrosis, and a significant increase in Kupffer cells.Item Effects of 8-Week Functional vs. Traditional Training on Athletic Performance and Functional Movement on Prepubertal Tennis PlayersYildiz, S; Pinar, S; Gelen, EYildiz, S, Pinar, S, and Gelen, E. Effects of 8-week functional vs. traditional training on athletic performance and functional movement on prepubertal tennis players. J Strength Cond Res 33(3): 651-661, 2019-In recent years, studies on functional training (FT) have gained importance among older adults and health care services, but there is a lack of research on the athletic performance of children. Fundamental movement skills are basic skills that need to be improved by the age of 10, and these skills are fundamental to every sport. While developing these basic movement skills, some athletic abilities of children should not be neglected and will be a basis for the future. In this way, children will have the ability to perform their sport-specific movement skills easily when the age of specialization comes. Our hypothesis is that increased functional movement will enhance athletic performance of child tennis players. Question of the study is will increased functional movement enhance athletic performance of child tennis players? The purpose of this study is to investigate the effects of the FT model on the athletic performance of young athletes. This study included 28 young tennis players (mean age: 9.6 +/- 0.7, height: 134.1 +/- 6.8, body mass: 31.3 +/- 4.1, and fitness age: 3.1 +/- 1.1) who have an 80% or more dominant side based on the lateralization test and a functional movement screen (FMS) score below 75%. Ten subjects were included in each of the FT group (FTG) and the traditional training group (TTG), 8 subjects were included in the control group (CG). The training program was implemented on 3 nonconsecutive days in a week for 8 weeks. All subjects performed CG exercises; FTG performed additional exercises based on the FT model, and TTG performed additional exercises based on the TT model. Flexibility, vertical jump, acceleration, agility, balance, and FMS tests were conducted before the training program, at the end of the fourth and the eighth week. The Friedman test analysis method bearing intragroup repeated measurements was used to evaluate the effects of the training program on the dependent variables among weeks (beginning the fourth week and the eighth week) since groups display distribution in nonparametric order. The differences between the averages were tested with Wilcoxon post hoc analyses. The Kruskal-Wallis Test analyses method was used to evaluate the effects of the training program on dependent variables among the groups (CG, TTG, and FTG). The differences between the averages were tested with Mann-Whitney U post hoc analyses. Intraclass correlation coefficient (ICC) values were calculated to determine the test-retest reliability of all measurements. According to the data, there was no difference in performance measurements between CG, TTG, and FTG before the exercise program (p > 0.05), but the differences between the groups were significant (p < 0.01) after 4 weeks and 8 weeks. A significant decrease was found in FMS score in CG (p < 0.01), while no difference was found in other parameters (p > 0.05). In TTG, FMS score significantly decreased (p < 0.01), dynamic right balance (p < 0.01) and dynamic left balance (p < 0.05) increased. But, no statistically significant difference was found in other parameters (p > 0.05) in TTG. In FTG, all parameters improved, and differences were statistically significant (p <= 0.001). Based on these results, the FT model seems to be more effective than the TT model in terms of increasing athletic performance.Item Investigation of histopathological and cytogenetic effects on Lepomis gibbosus (Pisces: Perciformes) in the Cine Stream (Aydin/Turkey) with determination of water pollutionKoca, YB; Koca, S; Yildiz, S; Gürcü, B; Osanç, E; Tunçbas, O; Aksoy, GWater quality and the distribution of some heavy metals in three different organs of Lepomis gibbosus from the Cine Stream were studied. Also, histopathological changes in gill, liver, and muscle tissue were examined at light microscopical level. Micronucleus (MN) formation in fish erytrocytes, as an indicator of chromosomal damage, has been increasingly used to detect the genotoxic potential of environmental contaminants. The frequency of MN was examined from samples of fish from the Cine Stream and a control group. MN frequency was higher in fish samples caught from the Cine Stream than that in the control group. The chemicals ammonia, nitrite, nitrate, orthophosphate, and sulphate were determined as parameters that possibly affect the gill, liver, and muscle morphology. Zn was the most accumulated metal in tissues as well as in water. Maximum metal accumulation occured in both liver and gills. For histopathological examinations, samples of gills, liver, and muscle tissues of L. gibbosus were studied by using light microscopy. In this study, a significant decrease in mean length of primary and secondary lamellae were observed. Moreover, cellular proliferation developed with secondary lamellae fusion, ballooning degenerations or club deformation of secondary lamellae, as well as distribution of necrotic, hyperplastic and clavate secondary lamellae. In the liver, altered staining, swollen and ruptured parenchymal cells, loss of cord structure, reduce of glycogen in hepatocytes, and vacuolar structure filled with cellular debris and many dark particles were seen. In muscle tissue, focal necrosis, cellular dissolution, and a decline or loss of striatation in muscle fibres were found. (C) 2005 Wiley Periodicals, Inc.Item Adsorbent effect of Chlorella vulgaris and Scenedesmus sp (Chlorophyta) for the removal of some heavy metals and nutrientsSentürk, T; Yildiz, SObjective: The aim of present manuscript is to evaluate the efficiency of two microalgae strains -Chlorella vulgaris and Scenedesmus sp- in removal of some inorganic nutrients and heavy metals. Methods: For this aim the green microalgae (Chlorophyta), grown in controlled laboratory conditions, were used as biosorbent for the removal of six different concentrations of Antimony (Sb3+), Manganese (Mn2+), Copper (Cu2+), Nickel (Ni2+), Phosphate (PO43-) and Nitrate (NO3-) which are prepared in aqueous solutions at conc. 0.1-1 mM for PO43-; 5-30 mM for NO3-; 2,5-100 ppm for heavy metals. Besides, the effects of heavy metals and inorganic nutrients on the cell's total carbohydrate and chlorophyll a-b content were investigated during 24 hours exposure. Results: According to the results, the average removal efficiency of Phosphate, Nitrate, Antimony, Manganese, Copper and Nickel on C. vulgaris biomass was determined 95.91%, 21.63%, 28.64%, 49.41%, 33.38% and 29.96% while 98.15%, 14.28%, 10.05%, 8.52%, 30.18% and 20.62% on Scenedesmus sp. cells, respectively. On the other hand, the average adsorption capacities of Sb3+, Mn2+, Cu2+, Ni2+, PO43- and NO3- ions were confirmed 0.18, 0.38, 0.28, 0.15, 1.18 and 9.30 mg g(-1) by C. vulgaris and 2.99, 0.96, 11.50, 11.33, 0.75 and 4.56 mg g(-1) by Scenedesmus sp. biomass. Conclusion: Result of this study suggests that Chlorella vulgaris and Scenedesmus sp. have a remarkable ability on removal of excessive nutrients and heavy metals at laboratory conditions.Item Determination of some physicochemical parameteres and inorganic nutrient content of Gediz River (Manisa)Sentürk, T; Yildiz, SObjective: This present investigation aimed at assessing the water quality of the Gediz River located in western Turkey. Methods: Some physicochemical parameters and nutrient concentrations of the surface water of Gediz River were determined over a period of twelve months (October to September 2012) at 5 sampling sites along the river. Results: Data on some ions namely NH4-N, NO2-N, NO3-N and PO-34-P were measured. The pH, temperature, electrical conductivity (EC), salinity and dissolved oxygen were also determined to assess the chemical status and pollution levels of the river. The measured data were given as mean, maximum, minimum values, respectively. In this context; the ranges for Water temperature [17.95 degrees C +/- 1.37 degrees C (30.2-4.5)], pH [7.45 +/- 0.06 (8.11-6.66)], Dissolved Oxygen [3.84 +/- 0.65 mg/L (6.25-2.43)], Electrical Conductivity (E.C) [1051.4 +/- 216.07 mu S/cm (3000-296)], Salinity [0,16 +/- 0,05 ppt (0,8-0,1)], Ammonium nitrogen (NH4-N) [1.772 +/- 0.8228 mg/L (4.642-0.057)], Nitrite nitrogen (NO2-N) [0.605 +/- 0.4224 mg/L (2.312-0.050)], Nitrate nitrogen (NO3-N) [46.014 +/- 44.9878 mg/L (151.965-2.855)], Phosphate phosphorus (PO-34-P) [5.489 +/- 3.6356 mg/L (20.350-0.190)] were found to be higher than the natural background levels for surface water. Conclusion: This indicates pollution of the river water samples from the areas studied. Our findings highlighted the deterioration of water quality of the river due to anthropogenic and agriculturel activities.Item THE RELATIONSHIP BETWEEN REACTION TIME, AGILITY AND SPEED PERFORMANCE IN HIGH-LEVEL SOCCER PLAYERSYildiz, S; Ates, O; Gelen, E; Çirak, E; Bakici, D; Sert, V; Kayihan, G; Ozkan, APurpose: In soccer, reaction time (RT), speed and agility are important athletic skills that affect the performance of athletes. The aim of our study was to examine the relationship between these three athletic skills. Materials and methods: In this study, 73 high-level, active soccer players having at least 5 years of game experience (training age 10.7 +/- 2.9 years) participated voluntarily. The physical characteristics of the soccer players were: height (177.8 +/- 5.5 cm), weight (73.6 +/- 8.1 kg), and age (22.0 +/- 2.7 years). The participant's tests which were taken on non-consecutive days measured RT (Visual reaction test, Lafayette, Multi-Operational Apparatus for Reaction Time (MOART) system), speed (15 m, Fusion Sport, Smart Speed) and agility (open skills (OS) and closed skills (CS), Fusion Sport, Smart Speed). Results: A significant correlation was found between agility (CS) and speed (p<0.05) however, there was no significant relationship between reaction time and agility (OS and CS) (p>0.05). Conclusion: The important athletic skills of speed and quick change of direction were shown to have an effect on each other. It may be of benefit to add change of direction drills to training programs in order to improve the speed performance of the athletes.Item Zooplankton composition of Van Lake Coastline in TurkeyYildiz, S; Özgökçe, MS; Özgökçe, F; Karaca, I; Polat, EThis study was completed with periodical surveys in coastal band of Van Lake between May and September in 2005 to 2006 period. It was carried out on a total of 20 sites selected as sampling points and having three distinct characteristics. During the study, a total of 20 species (14 belonged to genus of Rotifera, 4 to Copepoda and 2 Branchiopoda) were found at the Van Lake coastal zone. Genera Notholca squamula, Keratella quadrata, Colurella colurus, Lecane ohiensis, Lecane grandis and Lecane lamellata have been detected for the first time at the Van Lake coastal zone.Item Acute effects of static stretching and massage on flexibility and jumping performanceYildiz, S; Gelen, E; Çilli, M; Karaca, H; Kayihan, G; Ozkan, A; Sayaca, CObjective: The purpose of this study was to evaluate the effects of static stretching and the application of massage on flexibility and jump performance. Methods: Thirty-five athletes studying Physical Education at University (mean age 23.6 +/- 1.3 years. mean height 177.8 +/- 6.3 cm and mean weight 72.2 +/- 6.7 kg) performed one of three different warmup protocols on non-consecutive days. Protocols included static stretching ISS). combined static stretching and massage [SSW, and neither stretching nor massage [CONT]. The athletes performed flexibility, countermovement jump (CMJ) and squat jump (SJ) tests. Results: SS and SSM protocols demonstrated 12%(p<0.05) and 16% (p<0.05) respectively greater flexibility than the CONT protocol. SJ and CMJ performances were significantly decreased 10.4% (p<0.05) and 5.5% (p<0.05) respectively after the SS protocol. There was no significant difference between SSM and CONT protocol in terms of SJ and CMJ performance. Conclusion: This research indicates that whereas static stretching increases the flexibility it decreases the jumping performance of the athletes. On the other hand. the application of massage immediately following static stretching increases flexibility but does not reduce jumping performance. Considering the known negative acute effects of static stretching on performance. the application of massage is thought to be beneficial in alleviating such effects.Item Analysis of factors influencing target PASI responses and side effects of methotrexate monotherapy in plaque psoriasis: a multicenter study of 1521 patientsErduran, F; Emre, S; Hayran, Y; Adisen, E; Polat, AK; Üstüner, P; Öztürkcan, S; Öztürk, P; Ermertcan, AT; Selçuk, LB; Aksu, EK; Akbas, A; Kalkan, G; Demirseren, D; Kartal, SP; Topkarci, Z; Kilic, A; Yaldiz, M; Aytekin, S; Hizli, P; Gharehdaghi, S; Borlu, M; Isik, L; Botsali, BR; Solak, EO; Albayrak, H; Gönülal, M; Balci, DD; Polat, M; Daye, M; Ataseven, A; Yildiz, S; Özer, I; Zorlu, O; Dogan, S; Erdemir, VA; Dikicier, BSMethotrexate (MTX) is commonly used as first-line systemic treatment agent in psoriasis. We aimed to evaluate the clinical characteristics and treatment responses of patients with psoriasis undergoing MTX monotherapy. Data from adult patients with plaque psoriasis who received MTX monotherapy for at least 3 months between April 2012 and April 2022 were retrospectively evaluated in 19 tertiary care centers. Our study included 722 female and 799 male patients, a total of 1521 participants. The average age of the patients was 44.3 +/- 15.5 years. Mode of treatment was oral in 20.4% of patients while in 79.4% it was subcutaneous. The median treatment duration was 8 months (IQR = 5-15). The median weekly dose was 15 mg (IQR = 11-15). 1448 (95.2%) patients were taking folic acid supplementation. At week 12, 16.3% of the patients achieved PASI (Psoriasis Area and Severity Index) 90 response while at week 24, 37.3% achieved it. Logistic regression analysis for week 12 identified the following independent factors affecting PASI 90 achievement positively: median weekly MTX dose <= 15 mg (P = 0.011), subcutaneous administration (P = 0.005), no prior systemic treatment (< 0.001) and folic acid use (0.021). In logistic regression analysis for week 24; median weekly MTX dose <= 15 mg (P = 0.001), baseline PASI >= 10 (P < 0.001), no prior systemic treatment (P < 0.004), folic acid use (P = 0.001) and absence of comorbidities (P = 0.009) were determined as independent factors affecting the achievement of PASI 90. Adverse effects were observed in 38.8% of the patients, with nausea/vomiting (23.9%) and transaminase elevation (13%) being the most common. The most common reasons for interruptions (15.3%) and discontinuations (27.1%) of the treatment were patient related individual factors. The use of MTX as the first systemic treatment agent, at doses <= 15 mg/week and concurrent folic acid application are positive predictive factors for achieving the target PASI response both at weeks 12 and 24. In our study, which is one of the most comprehensive studies on MTX treatment in psoriasis, we observed that MTX is an effective and safe treatment option.Item Outcomes of high-risk breast lesions diagnosed using image-guided core needle biopsy: results from a multicenter retrospective studyOktay, A; Aslan, Ö; Taskin, F; Tunçbilek, N; Içten, SGE; Balci, P; Aribal, ME; Çelik, L; Örguç, IS; Demirkazik, FB; Gültekin, S; Aydin, AM; Durmaz, E; Kul, S; Binokay, F; Çetin, M; Emlik, GD; Akpinar, MG; Voyvoda, SNK; Polat, AV; Akin, IB; Yildiz, S; Poyraz, N; Özsoy, A; Öztekin, PS; Elverici, E; Bayrak, IK; Ikizceli, T; Dinç, F; Sezgin, G; Gülsen, G; Tunçbilek, I; Yalçin, SR; Çolakoglu, G; Aglamis, S; Yilmaz, R; Rona, G; Durhan, G; Güner, DC; Yabul, FÇ; Karabekmez, LG; Tutar, B; Göktas, M; Bugdayci, O; Suner, A; Özdemir, NPURPOSE The clinical management of high-risk lesions using image-guided biopsy is challenging. This study aimed to evaluate the rates at which such lesions were upgraded to malignancy and identify possible predictive factors for upgrading high-risk lesions. METHODS This retrospective multicenter analysis included 1.343 patients diagnosed with high-risk lesions using an image-guided core needle or vacuum-assisted biopsy (VAB). Only patients managed using an excisional biopsy or with at least one year of documented radiological follow-up were included. For each, the Breast Imaging Reporting and Data System (BI-RADS) category, number of samples, needle thickness, and lesion size were correlated with malignancy upgrade rates in different histologic subtypes. Pearson's chi-squared test, the Fisher-Freeman-Halton test, and Fisher's exact test were used for the sta-tistical analyses. RESULTS The overall upgrade rate was 20.6%, with the highest rates in the subtypes of intraductal papilloma (IP) with atypia (44.7%; 55/123), followed by atypical ductal hyperplasia (ADH) (38.4%; 144/375), lobular neoplasia (LN) (12.7%; 7/55), papilloma without atypia (9.4%; 58/611), flat epithelial atypia (FEA) (8.7%; 10/114), and radial scars (RSs) (4.6%; 3/65). There was a significant relationship between the upgrade rate and BI-RADS category, number of samples, and lesion size Lesion size was the most predictive factor for an upgrade in all subtypes.CONCLUSION ADH and atypical IP showed considerable upgrade rates to malignancy, requiring surgical excision. The LN, IP without atypia, pure FEA, and RS subtypes showed lower malignancy rates when the BI-RADS category was lower and in smaller lesions that had been adequately sampled using VAB. After being discussed in a multidisciplinary meeting, these cases could be managed with follow-up instead of excision.Item Histopathological and Genotoxic Effects of Pollution on Anguilla anguilla in the Gediz River (Turkey)Yildiz, S; Gurcu, B; Koca, YB; Koca, SThe aim of the present study was to determine heavy metal accumulation in water, sediment and some tissues of Anguilla anguilla along with determining histopathological and genotoxic effects of accumulation on these tissues by using light microscopy. Water, sediment and fish tissue samples taken from different sites of 3 different study areas were studied and the order of accumulation of metals was Fe>Pb>Mn>Co>Zn>Ni> Cr>Cu>Cd in water, Fe>Co>Mn>lpb>Zn>Ni>Cr>Cu>Cd in sediment and Cd>Mn>Cu>Cr>Ni>Fe>Zn>Co>lpb, Cd>lpb>Ni>Cr>Mn>Cu>Fe>Co>Zn and Cr>Ni>Zn>Cd>lpb>Mn>Cu>Fe>Co in liver, muscle and gill of fish, respectively. In histopathological studies, a decrease in the length of primary and secondary lamellae of gills, fusion in secondary lamellae, cellular proliferation, clavate lamellae formation and necrosis were observed. In liver tissue, dilation of sinusoid, increase in the number of erythrocytes, ruptured hepatocytes, decrease in glycogen accumulation and vacuolization were observed. In muscle tissue, necrosis, cellular dissolution and loss of striatation in muscle fibers were found. It was observed that pollution of water had no genotoxic effect on Anguilla anguilla.