Browsing by Author "Yildiz M."

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    The distribution and heterogeneity of mast cells in the cecum of quail (Coturnix coturnix japonica); [Bıldırcın (Coturnix Coturnix Japonica) sekumunda mast hücrelerinin dağılımı ve heterojenitesi]
    (Veteriner Fakultesi Dergisi, 2016) Yildiz M.; Aydemir I.; Kum Ş.; Eren Ü.
    The aim of the present study is to investigate the location and heterogeneity of mast cells in quail cecum. Cecum samples were fixed in basic lead acetate (BLA), Carnoy’s, isotonic formaldehyde acetic acid (IFAA) and 10% neutral buffered formalin (NBF) solutions. The sections were stained with an alcian blue-critical electrolyte concentration (AB-CEC) (pH 5.8, 0.3 M MgCl2) and safranin O (SO) (pH 1.0) used in a combined method and with toluidine blue (TB) (pH 0.5). Mast-cell population was shown in highest ratios in all layers of Carnoy fixed cecum parts within TB-stained sections. Metachromatic mast cell density was determined the most in tunica mucosa layers of the middle and distal cecum. It was seen that AB-CEC (+)/SO (-) mast-cell density was greater in tunica mucosa layers of the proximal and middle cecum in IFAA and BLA fixed tissues campare to Carnoy fixation. At the end of the study; it can be said that Carnoy solution fixed the connective tissue mast cells, as well as IFAA and BLA solutions fixed the mucosal mast cells better. © 2016, Veteriner Fakultesi Dergisi. All rights reserved.
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    Determination of antifungal efficiency of some fungicides and secondary metabolites of Trichoderma species against Botrytis cinerea
    (Triveni Enterprises, 2021) Savas N.G.; Yildiz M.; Eltem R.; Ozkale E.
    Aim: The present study aimed to investigate the antifungal effects of fenhexamid, cyprodinil+fludioxanil, Bacillus subtilis QST 713, Trichoderma secondary metabolites (EGE-K-38 and EGE-K-71) on 6 isolates of necrotrophic fungi (Botrytis cinerea) under in- vitro conditions. Methodology: A dual culture technique was used to evaluate the effects of volatile compounds produced by Trichoderma in culture media against Botrytis cinerea isolates. For non-volatile and volatile metabolites, measurements for growth inhibition were made with the mixture of filter sterilized liquid medium of Trichoderma and potato dextrose agar. The fungicidal effects of these non-volatile metabolites and fungicides were first evaluated according to the effective concentration (EC ) data of 50 growing mycelium inhibition of disease agents. Results: According to the results obtained, the drug/agent with the lowest fungicidal activity was determined as fenhexamide, which seems to have the lowest EC value of 0.05 ug m l-1. Both 50 non-volatile metabolites and volatile metabolites of Trichoderma strains showed strong inhibition against B. cinerea isolates under experimental conditions. The highest growth inhibition percentage was determined with volatile metabolites of Trihoderma atroviride EGE-K-71 strain as 71.8%. Interpretation: The study suggest that filtrates that contain secondary metabolites and volatile compounds of Trichoderma strains produced in both liquid culture and dual culture conditions can be used as an effective fungal control agents against pre and postharvest contamination of grapes with Botrytis cinerea. © 2021 Triveni Enterprises. All rights reserved.
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    Clinical and Demographic Characteristics of Treatment Requiring Retinopathy of Prematurity in Big Premature Infants in Turkiye: Report No. 1 (BIG-ROP Study)
    (S. Karger AG, 2024) Özdek Å.; Ozdemir H.B.; Ozen Tunay Z.; Bayramoglu S.E.; Alyamac Sukgen E.; Klr N.; Koç E.; Ekinci D.Y.; Sayin N.; Ceylan N.A.; Cebeci Z.; Çelik G.; Kizilay O.; Demir S.T.; Yildiz M.; Öztürk T.; Bekmez S.; Eris E.; Çömez A.; Mayali H.; Kabatas E.U.; Satirtav G.; Ögreden T.; Vural A.; Onur I.U.; Yeter D.Y.; Gönc T.; Tanidir S.T.; Akdogan M.; Çelemler P.; Beyazyildiz E.; Beyazyildiz Ö.; Acar D.E.; Özbay E.K.; Özcan Y.; Keles S.; Yildirim M.; Uzun A.; Dikci S.; Sari A.; Kara C.; Petriçli I.S.; Comba Ö.B.S.; Albayrak S.; Ersan B.A.; Bilgin B.; Çeliker H.; Sahin O.; Seymen Z.; Alaluf A.; Kaymak N.Z.; Oral A.Y.; Kerimoglu H.; Ünsal A.I.A.; Hirfanoglu I.M.; Tayman C.; Mert M.K.; Çetinkaya M.; Karatekin G.; Uslu S.; Özkan H.; Tüzün F.; Yildirim T.G.; Yurttutan S.; Dinlen N.F.; Bezirganoglu H.; Altinhan H.; Salihoglu Ö.; Tun G.; Karakurt D.G.; Bas A.Y.; Demiroglu Ö.B.; Aygün C.; Tekgündüz K.S.; Ceylan M.; Özdemir R.; Zübahiroglu U.; Özkiraz S.; Cömert S.; Akcan A.B.
    Introduction: The aim of the study was to analyse the clinical and demographic features of infants with gestational age (GA) of 32-37 weeks and birth weight (BW) of >1,500 g who developed treatment requiring retinopathy of prematurity (ROP). Methods: Data on the infants with a GA of 32-37 weeks and BW >1,500 g who developed treatment requiring ROP (TR-ROP) were collected retrospectively from the 33 ROP centres in Turkiye. GA, BW, type of hospital, neonatal intensive care units (NICUs) level, presence of an ophthalmologist and neonatologist in the same hospital, length of stay in NICU, duration of oxygen therapy, comorbidities, type of ROP, and timing for TR-ROP development were analysed. Results: A total of366 infants were included in the study. Mean GA and BW were 33 1 weeks and 1,896 316 g, respectively. Duration of hospitalization was 3-4 weeks in 46.8% of them. The first ROP examination was performed at postnatal 4-5 weeks in 80.3% of infants, which was significantly later in level 2 and lower NICUs and non-university clinics. At the first ROP examination, any stage of ROP was detected in 90.9% and TR-ROP was detected in 15.3% of the infants. The mean postnatal week of TR-ROP development was 6.16 2.04. Conclusion: Routine ROP screening thresholds need to be expanded in hospitals with suboptimal NICU conditions considering the development of TRROP in more mature and heavier preterm infants. The first ROP examination should be earlier than the fourth postnatal week. 2024 S. Karger AG, Basel. © 2024 S. Karger AG. All rights reserved.