Browsing by Author "Yilmaz, A"

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    The Effect of a Training Program on Oral Health and Behavior Change in Asthma Patients
    Yilmaz, FT; Çinar, S; Yilmaz, A; Kumsar, AK
    Background: Asthma is a chronic disease which is prevalent throughout the world. Physical problems such as deterioration in oral health, which may occur due to the triggering factors of asthma as well as the ineffective use of asthma medicine, seem to affect the daily lives of asthma patients. Therefore, it is important to protect oral health and promote positive behavior changes in asthma patients in order to achieve effective treatment and asthma control. Aims: The present study aimed to determine the effects of a training program provided for asthma patients on oral health, inhaler use skills, and behavior change. Study Design: Controlled experimental study. Methods: A total of 124 asthma patients were included in the study. Of the patients, 62 were assigned to the experimental group and the other 62 were assigned to the control group. Data were collected using the patient identification form, the oral assessment guide, the inhaler use skill form, and the evaluation form for behavior change over time. The experimental group received training provided by the researchers on the first meeting and one month later. Written and visual training material were used. Both groups were subject to a final evaluation which was conducted 4 months after their first meeting. Results: It was determined that the oral assessment guide scores (p<0.01) and inhaler use skills of the experimental group improved significantly after the training compared to the control group (p<0.01). In addition, it was observed that the number of patients in the experimental group who quit smoking (p<0.05), used their medicine (p<0.01) and brushed their teeth on a regular basis (p<0.01), and washed their mouth after inhaler use significantly increased in the experimental group after training compared to the control group (p<0.01). Conclusion: The study demonstrated that the training provided for asthma patients improved oral health and promoted inhaler use skills and was partially effective in promoting positive asthma-related behavior change.
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    Assessment of anxiety, depression, loneliness and stigmatization in patients with tuberculosis
    Yilmaz, A; Dedeli, O
    Objective: The purpose of this study was to assess anxiety, depression, loneliness, and stigmatization in patients with pulmonary tuberculosis. Methods: A descriptive and cross sectional study was conducted with 208 out-patients in a state hospital due to PT. A patient identification form, Tuberculosis Patients Stigma Scale (TPSS), Hospital Anxiety and Depression Scale (HAD) and University California of Los Angeles (UCLA) Loneliness Scale were used as data gathering forms. Arithmetic averages, standart deviation (SD), pergentage, and correlation were used in statistical analysis. Results: The prevalence of anxiety (26.0%), depression (60.5%), and loneliness (49.0%) was observed to be among patients with PT. It was found that patients with PT suffered from stigmatization (47.6%). Conclusion: In conclusion, patients with PT experience high level of depression, moderate-high level of loneliness, mild level of anxiety, and moderate level of stigmatization.
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    About Festival Scenes on Saymali Tash Petroglyphs
    Yilmaz, A
    Not only in Saymali Tash in Kyrgyzstan, but anywhere in Eurasian step belt, affected by Turkic culture, rock carvings (petroglyphs) can be found. In those glyphs anything can be subject: daily life acts, ritual performances or just a single inscription (tamga) which identify the area to specific tribe. Our research focused on festival scenes based on Saymali Tash. While the academicians prefer to use ritual dance to explain those glyphs yet it is not clear. So we want to put a new idea about why those people perform such as ritual. It is relatively rare if compared to archaeological artifacts and there is no sign left about their function from the people who carved them. That is why it is quite hard to reach definite conclusion. Article tries to explain, what may be the reason and what is the specific carving time of those glyphs, with the help of neighboring countries customs and with the interpretation of one of the oldest Turkish legend.
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    Urinary HSP70 improves diagnostic accuracy for urinary tract infection in children: UTILISE study
    Yilmaz, A; Afonso, AC; Akil, I; Aksu, B; Alpay, H; Atmis, B; Aydog, O; Bayram, MT; Bilge, I; Bulut, IK; Buyukkaragoz, B; Comak, E; Demir, BK; Dincel, N; Donmez, O; Durmus, MA; Dursun, H; Dusunsel, R; Duzova, A; Ertan, P; Gedikbasi, A; Goknar, N; Guven, S; Hacihamdioglu, D; Jankauskiene, A; Kalyoncu, M; Kavukcu, S; Kenan, BU; Kucuk, N; Kural, B; Montini, G; Morello, W; Nayir, A; Obrycki, L; Omer, B; Ozdemir, EM; Ozkayin, N; Paripovic, D; Pehlivanoglu, C; Saygili, S; Schaefer, S; Sonmez, F; Tabel, Y; Tas, N; Tasdemir, M; Teixeira, A; Tekcan, D; Tulpar, S; Turkkan, ON; Uysal, B; Uysalol, M; Vaiciuniene, D; Yavuz, S; Yel, S; Yildirim, T; Yildirim, ZY; Yildiz, N; Yuksel, S; Yurtseven, E; Schaefer, F; Topaloglu, R; Bayazit, AK; Litwin, M
    Background The accuracy of conventional urinalysis in diagnosing urinary tract infection (UTI) in children is limited, leading to unnecessary antibiotic exposure in a large fraction of patients. Urinary heat shock protein 70 (uHSP70) is a novel marker of acute urinary tract inflammation. We explored the added value of uHSP70 in discriminating UTI from other infections and conditions confused with UTI. Methods A total of 802 children from 37 pediatric centers in seven countries participated in the study. Patients diagnosed with UTI (n = 191), non-UTI infections (n = 178), contaminated urine samples (n = 50), asymptomatic bacteriuria (n = 26), and healthy controls (n = 75) were enrolled. Urine and serum levels of HSP70 were measured at presentation in all patients and after resolution of the infection in patients with confirmed UTI. Results Urinary (u)HSP70 was selectively elevated in children with UTI as compared to all other conditions (p < 0.0001). uHSP70 predicted UTI with 89% sensitivity and 82% specificity (AUC = 0.934). Among the 265 patients with suspected UTI, the uHSP70 > 48 ng/mL criterion identified the 172 children with subsequently confirmed UTI with 90% sensitivity and 82% specificity (AUC = 0.862), exceeding the individual diagnostic accuracy of leukocyturia, nitrite, and leukocyte esterase positivity. uHSP70 had completely normalized by the end of antibiotic therapy in the UTI patients. Serum HSP70 was not predictive. Conclusions Urine HSP70 is a novel non-invasive marker of UTI that improves the diagnostic accuracy of conventional urinalysis. We estimate that rapid urine HSP70 screening could spare empiric antibiotic administration in up to 80% of children with suspected UTI.
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    Pediatric kidney care experience after the 2023 Türkiye earthquake
    Bakkaloglu, SA; Delibas, A; Döven, SS; Taner, S; Yavuz, S; Erfidan, G; Vatansever, ED; Aynaci, F; Yílmaz, K; Tasdemir, M; Akaci, O; Akinci, N; Güven, S; Çiçek, N; Dursun, I; Kelesoglu, E; Sancaktar, M; Alaygut, D; Saygili, S; Yavascan, Ö; Yilmaz, A; Gülleroglu, K; Ertan, P; Demir, BK; Poyrazoglu, H; Pinarbasi, S; Gençler, A; Bastug, F; Günay, N; Çelegen, K; Noyan, A; Parmaksiz, G; Avci, B; Çayci, FS; Bayrakçi, U; Özlü, SG; Aksoy, ÖY; Yel, S; Inal, GA; Köse, S; Bayazit, AK; Atmis, B; Saribas, E; Çagli, Ç; Tabel, Y; Elmas, AT; Selçuk, SZ; Kiliç, BD; Kara, MA; Büyükçelik, M; Balat, A; Tiryaki, BD; Erdogdu, B; Aksu, B; Mahmudova, G; Dursun, H; Candan, C; Göknar, N; Mutlubas, F; Çamlar, SA; Basaran, C; Akbulut, BB; Düzova, A; Gülhan, B; Oruç, Ç; Peru, H; Alpay, H; Türkkan, ÖN; Gülmez, R; Çelakil, M; Dogan, K; Bilge, I; Pehlivanoglu, C; Büyükkaragöz, B; Leventoglu, E; Alpman, N; Zeybek, C; Tülpar, S; Gülsan, RYÇ; Kara, A; Gürgöze, MK; Önder, ENA; Atikel, YÖ; Pul, S; Sönmez, F; Yildiz, G; Akman, S; Elmaci, M; Küçük, N; Yüksel, S; Kavaz, A; Nalçacioglu, H; Alparslan, C; Dinçel, N; Elhan, AH; Sever, L
    Background. Two earthquakes on 6 February 2023 destroyed 10 cities in Turkiye. We report our experience with pediatric victims during these catastrophes, with a focus on crush syndrome related-acute kidney injury (Crush-AKI) and death. Method. Web-based software was prepared. Patient demographics, time under rubble (TUR), admission laboratory data, dialysis, and kidney and overall outcomes were recorded. Results. A total of 903 injured children (median age 11.62 years) were evaluated. Mean TUR was 13 h (interquartile range 32.5, max 240 h). Thirty-one of 32 patients with a TUR of >120 h survived. The patient who was rescued after 10 days survived. Two-thirds of the patients were given 50 mEq/L sodium bicarbonate in 0.45% sodium chloride solution on admission day. Fifty-eight percent of patients were given intravenous fluid (IVF) at a volume of 2000-3000 mL/m(2) body surface area (BSA), 40% at 3000-4000 mL/m(2) BSA and only 2% at >4000 mL/m(2) BSA. A total of 425 patients had surgeries, and 48 suffered from major bleeding. Amputations were recorded in 96 patients. Eighty-two and 66 patients required ventilator and inotropic support, respectively. Crush-AKI developed in 314 patients (36% of all patients). In all, 189 patients were dialyzed. Age >15 years, creatine phosphokinase (CK) >= 20 950 U/L, TUR >= 10 h and the first-day IVF volume <3000-4000 mL/m2 BSA were associated with Crush-AKI development. Twenty-two deaths were recorded, 20 of 22 occurring in patients with Crush-AKI and within the first 4 days of admission. All patients admitted after 7 days survived. Conclusions. These are the most extensive pediatric kidney disaster data obtained after an earthquake. Serum CK level was significantly associated with Crush-AKI at the levels of >20 950 U/L, but not with death. Adolescent age and initial IVF of less than 3000-4000 mL/m(2) BSA were also associated with Crush-AKI. Given that mildly injured victims can survive longer periods in the disaster field, we suggest uninterrupted rescue activity for at least 10 days.
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    Comparison of infants and children with urolithiasis: a large case series
    Bastug, F; Agbas, A; Tülpar, S; Yildirim, ZNY; Çiçek, N; Günay, N; Gemici, A; Çelik, B; Delebe, EÖÇ; Nalçacioglu, H; Yilmaz, A; Gökçe, I; Demircin, G; Hacihamdioglu, DÖ; Yilmaz, K; Atmis, B; Yilmaz, EK; Ertan, P; Dursun, I; Aksu, B; Akbulut, BB; Döven, SS; Öner, N; Yel, S; Elmaci, AM; Atikel, YÖ; Erfidan, G; Uysal, B; Biyikli, N; Yazicioglu, B; Küçük, N; Çomak, E; Sever, FL; Akil, I; Aksoy, Ö; Alpay, H
    We evaluated the demographic features, etiologic risk factors, treatment strategies, and outcome of the infants and children with urolithiasis (UL). A retrospective multicenter study was conducted including 23 Pediatric Nephrology centers in Turkey. The medical records of 2513 children with UL were reviewed. One thousand, three hundred and four boys and 1209 girls (1.1:1) were reported. The mean age at diagnosis was 39.5 +/- 35 months (0.4-231 months), and 1262 patients (50.2%) were in the first year of life (infants). Most of the cases with infantile UL were diagnosed incidentally. Microlithiasis (< 3 mm) was found in 794 patients (31.6%), and 64.5% of the patients with microlithiasis were infants. Stones were located in the pelvis-calyces in 63.2% (n: 1530) of the cases. The most common stone type was calcium oxalate (64.6%). Hypocitraturia was the most common metabolic risk factor (MRF) in children older than 12 months, but in infancy, hypercalciuria was more common. Fifty-five percent of the patients had received at least one medical treatment, mostly potassium citrate. At the end of a year's follow-up, most of the patients with microlithiasis (85%) showed spontaneous remission. The rate of spontaneous stone resolution in infants was higher than in children. Spontaneous remission rate was higher in cases with MRF ( - ) stones than in MRF ( +) stones. However, remission rate with medical treatment was higher in cases with MRF ( +) stones. This study represents the results of a large series of infants and children with UL and showed that there are several differences such as underlying metabolic and anatomic abnormalities, clinical course, and stone remission rates between infants and children with urinary stone disease.
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    A nationwide retrospective study in Turkish children with nephrocalcinosis
    Döven, SS; Tülpar, S; Bastug, F; Yildirim, ZNY; Yilmaz, EK; Çiçek, N; Küçük, N; Çomak, E; Yazicioglu, B; Nalcacioglu, H; Delibas, A; Uysal, B; Agbas, A; Gemici, A; Günay, N; Ertan, P; Biyikli, N; Hacihamdioglu, DO; Elmaci, AM; Atikel, YO; Delebe, EÖÇ; Sever, FL; Gökçe, I; Öner, N; Akman, S; Aksu, B; Atmis, B; Yel, S; Yilmaz, A; Çelik, B; Dursun, I; Alpay, H
    Background/aim: Nephrocalcinosis (NC) is defined as calcium deposition in the kidney parenchyma and tubules. This study aims to determine the etiology, risk factors, and follow-up results of patients with NC in Turkey. Materials and methods: Patients diagnosed with NC in the pediatric nephrology Department Units of 19 centers from all geographical regions of Turkey over a 10-year period (2010-2019) were included in the study. The medical records from the centers were reviewed and demographic data, admission complaints, medical history, systemic and genetic disorders, risk factors for NC, treatment details, and presence of NC after one-year follow-up, were recorded retrospectively. Results: The study sample included 195 patients (88 females, 107 males). The mean age at diagnosis was 39.44 +/- 47.25 (0.5-208) months; 82/190 patients (43.2%) were diagnosed incidentally; 46/195 patients (23.6%) had an underlying disease; idiopathic hypercalciuria was detected in 75/195 (38.4%) patients. The most common systemic diseases were distal renal tubular acidosis in 11/46 patients (23.9%), primary hyperoxaluria in 9/46 patients (19.6%) and Bartter syndrome in 7/46 patients (15.3%). After one year of follow-up, NC resolved in 56/159 patients (35.2%) and they all did not have an underlying systemic disease. Conclusion: The most common presentation of NC was incidental. Distal renal tubular acidosis and primary hyperoxaluria were the main systemic diseases leading to NC, while hypercalciuria was the most common metabolic risk factor. Nephrocalcinosis was found to remain in most of the patients at a one-year follow-up. It may resolve particularly in patients with no underlying systemic disease.
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    MEMBRANOUS NEPHROPATHY IN CHILDREN: A RETROSPECTIVE OBSERVATIONAL MULTICENTRE STUDY IN TURKEY
    Gokce, I; Sak, M; Bayram, MT; Aksoy, O; Melek, E; Yildirim, ZNY; Tekcan, D; Pinarbasi, AS; Soyaltin, E; Goknar, N; Serdaroglu, E; Ozcelik, G; Nalcacioglu, H; Tulpar, S; Ozkayin, N; Ozdogan, EB; Ertan, P; Buyan, N; Aydog, O; Bayrakci, US; Bayazit, AK; Soylu, A; Kavukcu, S; Yilmaz, A; Anarat, A
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    THE IMPACT OF PHYSICAL AND PSYCHOLOGICAL COMORBID CONDITIONS ON THE QUALITY OF LIFE OF PATIENTS WITH ACUTE MYOCARDIAL INFARCTION: A MULTI-CENTER, CROSS-SECTIONAL OBSERVATIONAL STUDY FROM TURKEY
    Sertoz, OO; Aydemir, O; Gulpek, D; Elbi, H; Ozenli, Y; Yilmaz, A; Ozan, E; Atesci, F; Abay, E; Semiz, M; Direk, N; Hocaoglu, C; Elyas, Z; Ozmen, M; Ozen, S; Konuk, N
    Objective: Acute myocardial infarction (MI) has significant and detrimental effects on the lifestyles of the patients. It has been shown that quality of life (QoL) in patients with MI is impaired in every aspect. This study aims to evaluate the impact of depression and physical comorbidity on QoL in Turkish patients with acute first MI. Method: This multi-center cross-sectional study was carried out in 15 centers with 998 patients hospitalized for acute first MI. For detection of depression, Beck Depression Inventory (BDI) was used. For evaluation of QoL, World Health Organization Quality of Life Questionnaire (WHOQOL) was applied. Results: The mean age of the patients was 57.5 +/- 10.1 years and 79.2 % (n = 792) of the patients were men. Patients with comorbid depression (BDI >= 10) and comorbid medical conditions, and female patients had significantly lower scores in every domain of WHOQOL. In the regression analysis model, female gender, low education, comorbid medical conditions, especially comorbid hypertension, and BDI score were found to have a significant effect on the domains of WHOQOL. Conclusions: Female patients are more prone to impairment in quality of life after myocardial infarction. Both comorbid medical conditions and depression have a significant impact on the impairment of QoL in Turkish patients with acute MI. In order to improve the subjective wellbeing of post MI patients, both psychiatric and physical comorbidities must be detected and managed even in the short term.
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    The 6th of February earthquake and the Turkish Society of Pediatric Nephrology-organizational aspects of pediatric kidney care
    Bakkaloglu, SA; Yavascan, Ö; Yilmaz, A; Gülleroglu, K; Demir, BK; Ertan, P; Poyrazoglu, H
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    TURKISH SOCIETY OF PEDIATRIC NEPHROLOGY - FEBRUARY 6TH EARTHQUAKES DISASTER MANAGEMENT
    Bakkaloglu, S; Yavascan, Ö; Yilmaz, A; Gulleroglu, K; Kasap-Demir, B; Ertan, P; Poyrazoglu, H
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    Validity and Reliability of Nine Types Temperament Scale
    Yilmaz, ED; Gençer, AG; Aydemir, Ö; Yilmaz, A; Kesebir, S; Ünal, Ö; Örek, A; Bilici, M
    The aim of this study is to develop a scale compatible with the Nine Types Temperament Model (NTTM), which did not have any prior measurement tools to scientifically prove its reliability and validity. NTTM is created by re-evaluating the Enneagram System a system that defines nine personality types- used for analyzing and comprehending ego mechanisms. Nine Types Temperament Scale (NTTS) which is a self-rated instrument composed of 91 items with three-point Likert type was developed from this model and applied to 990 participants. Confirmatory factor analyses were carried out in order to evaluate whether the scale fits to the model related to the temperament model. In exploratory factor analyses of the scale eigen values of nine factors vary between 8.089 and 1.661, and represent 39.04% of the total variance. In confirmatory analyses of the scale CFI value is 0.88, GFI value is 0.84, IFI value is 0.88 and RMSEA value is 0.05. Test-retest reliability of the scale was evaluated with 46 participants. Cronbach alpha value of the whole scale is 0.75, while Cronbach alpha values for every temperament type were calculated as 0.77, 0.79, 0.68, 0.71, 0.80, 0.74, 0.71, 0.83 and 0.77 respectively. Concurrent validity was performed with Cloninger's TCI (Temperament and Character Inventory) and Akiskal's TEMPS-A (Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire Version). The types of NTTM showed significant correlations with TCI and TEMPS-A. Results of the study support that NTTS is a reliable and valid scale.
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    Determination of a predictive cutoff value of NT-proBNP testing for long-term survival in ED patients with acute heart failure
    Velibey, Y; Golcuk, Y; Golcuk, B; Oray, D; Atilla, OD; Colak, A; Kurtulmus, Y; Erbay, AR; Yilmaz, A; Eren, M
    Objective: The main objective of this study was to determine a predictive cutoff value for plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) that could successfully predict the long-term (4-year) survival of patients with acute heart failure (HF) at the time of admission to the emergency department (ED). To our best knowledge, our study is the first research done to identify a predictive cutoff value for admission NT-proBNP to the prescriptive 4-year survival of patients admitted to ED with acute HF diagnosis. Methods: NT-proBNP levels were measured in plasma obtained from 99 patients with dyspnea and left ventricular dysfunction upon admission to the ED. The end point was survival from the time of inclusion through 4 years. Results: The mean age of the patients in this study was 71.1 +/- 10.3 years; 50 of these patients were female. During the 4-year follow-up period, 76 patients died; survivors were significantly younger than non-survivors (64.26 +/- 11.42 years vs 72.83 +/- 11.07 years, P-.002). The optimal NT-proBNP cutoff point for predicting 4-year survival at the time of admission was 2300 pg/mL, which had 85.9% sensitivity and 39.1% specificity (95% confidence interval, area under the curve: 0.639, P = .044). Conclusion: Elevated NT-proBNP levels at the time of admission are a strong and independent predictor of all-cause mortality in patients with acute HF 4 years after admission. Furthermore, the optimal cutoff level of NT-proBNP used to predict 4-year survival had high sensitivity. However, especially in the case of long-term survival, additional prospective, large, and multicenter studies are required to confirm our results. (C) 2013 Elsevier Inc. All rights reserved.
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    Environmental Radioactivity and High Incidence Rates of Stomach and Esophagus Cancer in the Van Lake Region: A Causal Relationship?
    Akan, Z; Baskurt, B; Asliyuksek, H; Kam, E; Yilmaz, A; Yuksel, MB; Biyik, R; Esen, R; Koca, D
    This study examined the incidence rates of cancer cases (averages for 2006-2010) and relationships with environmental radioactivity levels. Soil and water samples were collected from provincial and district centers of Van city and the outdoor gamma doses were determined using a portable gamma scintillation detector. Gross alpha and beta, (226)Ra, (232)Th, and (40) K activities were measured in both tap water and soil samples. Although high rates of stomach and esophagus cancers have been reported previously in Van the underlying reasons have not hitherto been defined. Incidences of cancers were highest in the Gurpinar (326.0) and Ozalp (377.1) counties (p<0.001). As to the results of the gross alpha and gross beta radioactivity measurements in the drinking water, these two counties also had high beta radionuclide levels: Gurpinar (140 mBq/dm(3)) and Ozalp (206 mBq/dm(3)). Even if within the normal range, a relation between the higher rate of the incidence of stomach and esophagus cancers with that of the higher rate of beta radionuclide activity was clear. On Spearman correlation analysis, the relation between higher beta radionuclide levels and cancer incidence was found to be statistically significant (p<0.01). According to the results of the analysis, Van residents receive an average 1.86 mSv/y annual dose from outdoor gamma radiation, ingestion of radionuclides in the drinking water, and indoor Rn-222 activity. Moreover, gross alpha and beta activities were found to be extremely high in all of the lakes around the city of Van, Turkey. Further investigations with long-term detailed environmental radiation measurements are needed regarding the relationship between cancer cases and environmental radioactivity in the city of Van.
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    The initial detection of Toscana virus in phlebotomine sandflies from Turkey
    Özbel, Y; Oguz, G; Arserim, SK; Kasap, ÖE; Karaoglu, B; Yilmaz, A; Emanet, N; Günay, F; Hacioglu, S; Demirok, MC; Töz, S; Alten, B; Nalçaci, M; Özkul, A; Ergünay, K
    Toscana virus (TOSV) is a prominent arthropod-borne viral agent of human central nervous system infections occurring in the Mediterranean region. The main transmission route to susceptible individuals involves sandflies as vectors. Despite several reports revealing widespread TOSV activity in Turkey, vectors remained unidentified. A sandfly field survey was carried out in five provinces in Central, Southeast and Mediterranean Anatolia in 2017 to identify TOSV and related sandfly-borne phleboviruses and Leishmania parasites, with evidence for circulation in the region. A total of 7136 sandfly specimens, collected via standard methods, were evaluated in 163 pools. TOSV was detected in 11 pools (6.7%), comprising Phlebotomus major sensu lato, Sergentomyia dentata and Phlebotomus papatasi species. TOSV partial L and S segment sequences were characterized, that phylogenetically clustered with local and global genotype A strains. An amino acid substitution outside the conserved motifs of the viral polymerase, also present in previous TOSV sequences in endemic regions, was observed. Leishmania tropica was detected in a single pool of Ph. sergentii (0.6%). This is the first report of TOSV in sandflies from Turkey, and this study further provides evidence for additional sandfly species with the potential to transmit TOSV.
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    Gastrostomy in Hospitalized Patients with Acute Stroke: NoroTek Turkey Point Prevalence Study Subgroup Analysis
    Topçuoglu, MA; Özdemir, AÖ; Aykaç, Ö; Milanoglu, A; Gökçe, M; Bavli, S; Çabalar, M; Yayla, V; Erdogan, HA; Özkul, A; Günes, A; Degirmenci, B; Aluçlu, U; Kozak, HH; Güngör, L; Erdogan, M; Acar, ZÖ; Cenikli, U; Kablan, Y; Yilmaz, A; Genç, H; Nazliel, B; Çaglayan, HB; Gencer, ES; Ay, H; Demirbas, H; Akdogan, Ö; Emre, U; Yildiz, ÖK; Bolayir, A; Demir, T; Tanriverdi, Z; Tekan, ÜY; Akpinar, ÇK; Özkan, E; Ilik, F; Sirin, H; Güler, A; Önder, H; Bektas, H; Öcek, L; Bakar, M; Ongun, N; Krespi, Y; Isikay, CT; Aslanbaba, E; Sorgun, M; Gürkas, E; Karadeli, HH; Midi, I; Ilgezdi, I; Bilgiç, AB; Akyol, S; Epçeliden, MT; Atmaca, MM; Kursun, O; Keskin, O; Sirinocak, PB; Baydemir, R; Akçakoyunlu, M; Öztürk, S; Özel, T; Ünal, A; Dora, B; Yürekli, VA; Arlier, Z; Eren, A; Yilmaz, A; Kisabay, A; Acar, B; Bastan, B; Acar, Z; Niflioglu, B; Güven, B; Kaya, D; Afsar, N; Yazici, D; Aytaç, E; Yaka, E; Toplutas, E; Degirmenci, E; Ince, FB; Büyükserbetçi, G; Aydin, I; Çetiner, M; Sen, M; Turgut, N; Kale, N; Çoban, E; Yesilot, N; Ekizoglu, E; Kizek, Ö; Birgili, Ö; Yevgi, R; Kunt, R; Giray, S; Akkas, SY; Senadim, S; Yoldas, T; Asil, T; Duman, T; Atasoy, T; Çinar, BP; Demir, T; Can, U; Ünsal, YÖ; Eskut, N; Aslan, Y; Bas, DF; Sener, U; Yilmaz, Z; Bozdogan, Z; Alioglu, Z; Arsava, EM
    Objective: Nutritional status assessment, dysphagia evaluation and enteral feeding decision are important determinants of prognosis in acute neurovascular diseases. Materials and Methods: NoroTek is a point prevalence study conducted with the participation of 87 hospitals spread across all health sub regions of Turkey conducted on 10-May-2018 (World Stroke Awareness Day). A total of 972 hospitalized neurovascular patients [female: 53%, age: 69 +/- 14; acute ischemic stroke in 845; intracerebral hematoma (ICH) in 119 and post-resuscitation encephalopathy (PRE) in 8] with complete data were included in this sub-study. Results: Gastrostomy was inserted in 10.7% of the patients with ischemic stroke, 10.1% of the patients with ICH and in 50% of the patients with PRE. Independent predictors of percutaneous endoscopic gastrostomy (PEG) administration were The National Institutes of Health Stroke Scale score at admission [exp (ss): 1.09 95% confidence interval (CI): 1.05-1.14, per point] in ischemic stroke; and mechanical ventilation in ischemic [exp (ss): 6.18 (95% CI: 3.16-12.09)] and hemorrhagic strokes [exp (ss): 26.48 (95% CI: 1.36-515.8)]. PEG was found to be a significant negative indicator of favorable (modified Rankin's scale score 0-2) functional outcome [exp (ss): 0.032 (95% CI: 0.004-0.251)] but not of in-hospital mortality [exp (ss): 1.731 (95% CI: 0.785-3.829)]. Nutritional and swallowing assessments were performed in approximately two-thirds of patients. Of the nutritional assessments 69% and 76% of dysphagia assessments were completed within the first 2 days. Tube feeding was performed in 39% of the patients. In 83.5% of them, tube was inserted in the first 2 days; 28% of the patients with feeding tube had PEG later. Conclusion: The NoroTek study provided the first reliable and large-scale data on key quality metrics of nutrition practice in acute stroke in Turkey. In terms of being economical and accurate it makes sense to use the point prevalence method.
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    Evaluation of factors affecting bone mineral density in CF patients through CF registry of Turkey
    Soydas, SSA; Tugcu, GD; Gençoglu, MY; Cinel, G; Emiralioglu, N; Yalçin, E; Kiper, N; Sen,; Altintas, DU; Çokugras, H; Kilinç, AA; Yazan, H; Ünal, G; Yilmaz, A; Çaglar, HT; Damadoglu, E; Irmak, I; Demir, E; Öztürk, GK; Bingöl, A; Basaran, E; Sapan, N; Aslan, AT; Asfuroglu, P; Harmanci, K; Köse, M; Hangül, M; Özdemir, A; Özcan, G; Gayretli, ZG; Keskin, Ö; Yüksel, H; Özdogan, S; Topal, E; Çaltepe, G; Can, D; Ekren, PK; Kiliç, M; Eyüboglu, TS; Pekcan, S; Çobanoglu, N; Çakir, E; Özçelik, U; Dogru, D
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    The efficacy of inhaled hypertonic saline in children with cystic fibrosis who receive daily DNase.
    Gencoglu, MY; Tugcu, GD; Soydas, SSA; Cinel, G; Emiralioglu, N; Yalçin, E; Kiper, N; Sen,; Altintas, DU; Çokugras, H; Kilinç, AA; Yazan, H; Ünal, G; Yilmaz, A; Çaglar, HT; Damadoglu, E; Irmak, I; Demir, E; Öztürk, G; Bingöl, A; Basaran, E; Sapan, N; Aslan, AT; Asfuroglu, P; Harmanci, K; Köse, M; Hangül, M; Özdemir, A; Özcan, G; Gayretli, ZG; Keskin, Ö; Yüksel, H; Özdogan, S; Topal, E; Çaltepe, G; Can, D; Ekren, PK; Kiliç, M; Eyüboglu, TS; Pekcan, S; Çobanoglu, N; Çakir, E; Özçelik, U; Dogru, D