Browsing by Author "Zamani A."
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Item Epidemiology and distribution of interstitial lung diseases in Turkey(2014) Musellim B.; Okumus G.; Uzaslan E.; Akgün M.; Cetinkaya E.; Turan O.; Akkoclu A.; Hazar A.; Kokturk N.; Calisir H.C.; Sever F.; Kiter G.; Celik G.; Bilgin S.; Kurutepe M.; Uzun O.; Tabak L.; Ozdemir O.; Turker H.; Ogus C.; Kiral N.; Ozkan M.; Yalniz E.; Camsari G.; Dogan T.; Yilmaz U.; Cildag O.; Yildiz F.; Hanta I.; Oztuna F.; Arik D.; Goktalay T.; Kanmaz D.; Yilmaz V.; Altiay G.; Komurcuoglu B.; Ozkan G.; Erbaycu A.; Dogrul M.I.; Ongen G.; Tuncay E.; Dabak G.; Sakar A.; Bircan A.; Uzel I.; Kalpaklioglu F.; Gülbay B; Bulbul Y.; Gulbanu H.; Havlucu Y.; Ekici Z.; Zamani A.; Caglayan B.; Kayacan O.; Dursunoglu N.Introduction: There is very few data on the epidemiological features of interstitial lung diseases (ILD) in the literature. These studies on this subject suffer from limited number of patients. Objective: The goal of this study was to evaluate the epidemiological features of ILD in Turkey. Methods: Fifty-four investigators, 31 centres in 19 cities from six regions of Turkey, participated in the study. Two thousand two hundred forty-five newly diagnosed patients (51.8% females), led by Turkish Thoracic Society Clinical Problems Study Group, enrolled in this prospective study. Results: The mean age was 51.8±16.7 years. The mean age among males was 50.5±18.6 years and 53.0±14.6 years among females (P<0.001). 23.8% of the cases had ILD with known causes, while 39.4% were in granulomatous group, 23.7% were idiopathic, and 4.4% were in the unclassified group. Overall, histopathologically confirmed diagnosis rate was 40.4%. Sarcoidosis was the most common disease (37%), whereas cases with idiopathic pulmonary fibrosis (IPF) constituted 19,9% of patients. 53% of the sarcoidosis patients were females, and the ratio reaches to 75% under 50 years of age (for this group, IPF ratio is %3). In contrast, sarcoidosis and IPF ratios were equal in males (25%). Sarcoidosis was 8% in men over 50, while IPF was %45. Conclusion: The overall incidence of ILD in Turkey was computed to be 25.8/100000. © 2013 John Wiley & Sons Ltd.Item First record of Filistata lehtineni Marusik & Zonstein, 2014 for the fauna of Iran (Araneae: Filistatidae)(Universitatea din Oradea, 2016) Moradi M.; Yaǧmur E.A.; Moradi Ghrakhloo P.; Zamani A.Filistata lehtineni Marusik & Zonstein, 2014, previously known from Azerbaijan is recorded for the first time from Iran. Zoogeographical remarks and figures of the newly recorded species are presented. ©Biharean Biologist, 2016.Item Effect of Asbestos Exposure on the Frequency of EGFR Mutations and ALK/ROS1 Rearrangements in Patients With Lung Adenocarcinoma: A Multicentric Study(Lippincott Williams and Wilkins, 2021) Yilmaz S.; Demirci N.Y.; Metintas S.; Zamani A.; Karadag M.; Guçlu O.A.; Kabalak P.A.; Yilmaz U.; Ak G.; Kizilgoz D.; Ozturk A.; Yilmaz U.; Batum O.; Kavas M.; Serifoglu I.; Unsal M.; Komurcuoglu B.E.; Cengiz T.I.; Ulubay G.; Ozdemirel T.S.; Ozyurek B.A.; Kavurgacı S.; Alizoroglu D.; Celik P.; Erdogan Y.; In E.; Aksoy A.; Altin S.; Gunluoglu G.; Metintas M.Objective: The aim of this study is to investigate the effect of asbestos exposure on cancer-driver mutations. Methods: Between January 2014 and September 2018, epidermal growth factor receptor (EGFR), anaplastic lymphoma receptor tyrosine kinase (ALK), and c-ros oncogene 1 receptor tyrosine kinase gene (ROS1) alterations, demographic characteristics, asbestos exposure, and asbestos-related radiological findings of 1904 patients with lung adenocarcinoma were recorded. Results: The frequencies of EGFR mutations, ALK, and ROS1 rearrangements were 14.5%, 3.7%, and 0.9%, respectively. The rates of EGFR mutations and ALK rearrangements were more frequent in asbestos exposed non-smokers (48.7% and 9%, respectively). EGFR mutation rate was correlated to female gender and not-smoking, ALK rearrangement rate was correlated to younger age, not-smoking, and a history of asbestos exposure. Conclusions: The higher rate of ALK rearrangements in asbestos-exposed lung adenocarcinoma cases shows that asbestos exposure may most likely cause genetic alterations that drive pulmonary adenocarcinogenesis. Copyright © 2020 American College of Occupational and Environmental Medicine.Item A new species of Anatextrix Kaya, Zamani, Yağmur & Marusik, 2023 (Araneae, Agelenidae, Textricini) from southern Türkiye, with a remarkable morphology of the male palpal femur(Pensoft Publishers, 2023) Kaya R.S.; Zamani A.; Yağmur E.A.; Marusik Y.M.Anatextrix monstrabilis sp. nov. (Araneae: Agelenidae) is described and illustrated, based on male and female specimens collected from Adana Province, Türkiye. The new species has an L-shaped male palpal femur bearing multiple apophyses, which is a rare trait in spiders. Anatextrix monstrabilis sp. nov. is the second species of the recently described genus Anatextrix Kaya, Zamani, Yağmur & Marusik, 2023, currently known only from southern Türkiye. © This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Item A new genus of Textricini Lehtinen, 1967 (Araneae, Agelenidae) from Anatolia(Pensoft Publishers, 2023) Kaya R.S.; Zamani A.; Yağmur E.A.; Marusik Y.M.Türkiye is known to have the highest diversity of the spider family Agelenidae in the Western Palaearctic and the highest diversity of the subfamily Ageleninae globally. The new agelenid genus Anatextrix gen. nov. (Ageleninae, Textricini) and its type species, A. spectabilis sp. nov. (♂♀; Mersin and Adana provinces, southern Türkiye), are described. A key to all four genera of Textricini is provided. © Rahşen S. Kaya et al.Item Clinical Course of Coronavirus disease 2019 C-19 in Patients with Bronchiectasis(AVES, 2024) Edis E.Ç.; Çilli A.; Kızılırmak D.; Coşkun A.Ş.; Sayıner A.; Çiçek S.; Gülmez İ.; Ağca M.Ç.; Çağlayan B.; Özçelik N.; Köktürk N.; Ocaklı B.; Uçan E.S.; Günlüoğlu G.; Niksarlıoğlu Y.; Zamani A.; Berk S.; Barış S.A.; Başyiğit İ.; Gülhan P.Y.; Kabak M.; Çolak M.; Toprak O.B.; Berk H.; Oğuzülgen K.; Demirdöğen E.; Eyüboğlu F.Ö.; Havlucu Y.; Babayiğit C.OBJECTIVE: Coronavirus disease 2019 (COVID-19) has affected the whole world and caused the death of more than 6 million people. The disease has been observed to have a more severe course in patients with chronic lung diseases. There are limited data regarding COVID-19 in patients with bronchiectasis. The aim of this article is to investigate the course of COVID-19 and factors affecting the clinical outcome in patients with bronchiectasis. MATERIAL AND METHODS: This study was conducted using the Turkish Adult Bronchiectasis Database (TEBVEB) to which 25 centers in Türkiye contributed between March 2019 and January 2022. The database consisted of 1035 patients, and COVID-19-related data were recorded for 606 patients. RESULTS: One hundred nineteen (19.6%) of the bronchiectasis patients (64 female, mean age 57.3 ± 13.9) had COVID-19. Patients with bronchiectasis who developed COVID-19 more frequently had other comorbidities (P = .034). They also more frequently had cystic bron-chiectasis (P = .009) and their Bronchiectasis Severity Index was significantly higher (P = .019). Eighty-two (68.9%) of the patients who had COVID-19 were followed up in the outpatient clinic, 27 (22.7%) in the inpatient ward and 10 (8.4%) patients in the intensive care unit. There tended to be a higher percentage of males among patients admitted to the hospital (P = .073); similarly, the mean age of the patients admitted to the hospital was also higher (60.8 vs 55.8 years for the outpatients), but these differences did not reach statistical significance (P = .071). CONCLUSION: In conclusion, this study showed that severe bronchiectasis, presence of cystic bronchiectasis and worse Bronchiectasis Severity Index are associated with the development of COVID-19, but not with the severity of infection. © 2024, AVES. All rights reserved.