Browsing by Publisher "AMG Transcend Association"

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    Electrospraying of zein for the preparation of micro/nano-particles loaded with sarcopoterium spinosum extract
    (AMG Transcend Association, 2019) Süngüc C.; Erdogan İ.; Uslu M.E.; Bayraktar O.
    Natural compounds that are isolated from various plant species have been the focus of folk medicine due to their bioactivities. Pharmaceutical, food and cosmetic industries also utilize these natural compounds with antioxidant and antimicrobial properties. Harsh processing and storage conditions causing loss of their bioactivities limit their applications. Therefore, biopolymeric carrier systems are required to preserve the natural bioactive compounds stability. Sarcopoterium spinosum is used in folkloric medicine for curing diabetes, gastrointestinal illnesses, cancer and pain. In this study, both solution and process parameters for electrospraying technique were investigated to encapsulate S. spinosum extract including natural bioactive compounds in zein particles. The best results were observed in 5% (w/v) of zein concentration in 70% aqueous ethanol. 0.3 ml/hour flow rate and 14 kV applied voltage were used in order to obtain narrow size distributionorbicular and smooth particle structure. The best mixture of S. spinosum extract and zein was achieved at weight ratio of 1:5. The zein microparticles with extract showed remarkable antioxidant activity. © 2019, AMG Transcend Association. All rights reserved.
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    Evaluation of the hemostatic activity of Equisetum arvense extract: The role of varying phenolic composition and antioxidant activity due to different extraction conditions
    (AMG Transcend Association, 2019) Uslu M.E.; Mele A.; Bayraktar O.
    Hemostasis is a procedure that causes bleeding to stop and is very important in injuries. Recent researches were focused on the discovery of plant hemostatic agents. Therefore, plant extracts were investigated as a major source as a hemostatic agent. In this research, Equisetum arvense extract was investigated as a candidate coagulatory agent. Effect of extraction parameters on coagulation was investigated. Although it has been stated in the literature that the extract of Equisetum arvense has anticoagulatory activity, it has been shown in this study that alteration of the extraction parameters changes the extract bioactivity from the anticoagulant to the coagulant. © 2019 by the authors.
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    Development and Characterization of Silk Fibroin-based Oral Films Containing Turmeric Extract as Dietary Supplement
    (AMG Transcend Association, 2023) Uslu M.E.; Bayraktar O.
    Dietary supplements have extreme importance. Due to the easily degradable nature of these supplements, the development and application of carrier systems in food technologies seem to be extremely important. Today, oral film technologies have gained importance due to their rapid and high absorption properties. This study chose silk fibroin (SF) as the main component due to its high biocompatibility. Turmeric extract has been added to the oral films as an active agent. The prepared films were analyzed with atomic force microscopy (AFM) and scanning electron microscopy (SEM) to reveal their morphological properties, and at the same time, the film thickness was measured. It has been found that the increase in extract amount is a factor that causes an increase in film roughness while causing a decrease in phase separation. It was observed that the film roughness increased twice with the addition of extract. The roughness of the films formed with 15% extract was measured as 28.5. The average roughness of the films formed without the use of extracts was observed as 15.7 mm. It was also observed that the Trolox equivalent antioxidant capacity (TEAC) was doubled for films containing 15% turmeric extract after one hour of release. The films exhibited different weight loss profiles after release as the amount of turmeric extract was changed. Disc diffusion experiments revealed that films containing turmeric extract exhibited antimicrobial effects. © 2022 by the authors.