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Browsing by Publisher "AVES Ibrahim Kara"

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Seroprevalance of measles, rubella, mumps, varicella, diphtheria, tetanus and hepatitis b in healthcare workers; [Saǧli{dotless}k çali{dotless}şanlari{dotless}nda ki{dotless}zami{dotless}k, ki{dotless}zami{dotless}kçi{dotless}k, kabakulak, suçiçeǧi, difteri, tetanos ve hepatit b seroprevalansi{dotless}]
(AVES Ibrahim Kara, 2013) Ciliz N.; Gazi H.; Ecemiş T.; Şenol S.; Akçali S.; Kurutepe S.
Objective: We aimed to determine the antibody levels of healthcare workers of Celal Bayar University Hospital against vaccinepreventable diseases such as measles, rubella, mumps, diphtheria, tetanus, varicella and hepatitis B, and encourage compliance to recommended vaccinations for non-immune staff. Methods: The antibody levels were tested by enzyme-linked immunosorbent assay (ELISA). Demographic characteristics were collected by a questionnaire, and the history of the diseases, immunization and the sharps-related injuries were queried. Results: 44% percent of 309 healthcare personnel were exposed to occupational injury at least once, and 78.3% of the injuries were needle-stick injuries. Injuries were found to be more common among doctors and nurses, and pediatric and surgical departments, respectively. Frequency of anti-HBs positivity among healthcare workers was 84.1%, while 71.5% of healthcare workers were immunized with HBV vaccine before starting to work, and the immunization status directly correlated with the level of education. In general, high seropositivity was noted for measles (99.7%), rubella (97.0%), mumps (99.7%) and varicella (99.7%), while diphtheria (60.8%) and tetanus (93.5%) antibody levels significantly decreased with age. Histories of the disease and vaccination were not reliable while verifying the immunity status. Conclusions: It is necessary to increase adherence to universal protective measures in healthcare workers and to take corrective and protective measures for sharps-related injuries. It is also essential to increase hepatitis B vaccination rates and to confirm the immune status of medical staff working in high risk departments and diphtheria and tetanus vaccinations should be repeated once every ten years.
The relationship between anxiety, pain distress and pain severity before and after open heart surgery in patients; [Açi{dotless}k kalp cerrahisi öncesi ve sonrasi{dotless} hastalari{dotless}n kaygi{dotless} ve aǧri distresi: Aǧri{dotless} düzeyi ile i̇lişkisinin i̇ncelenmesi]
(AVES Ibrahim Kara, 2013) Sidar A.; Dedeli O.; Işkesen A.I.
Objective: The aim of this study was to examine the pain severity, presence of anxiety and pain distress in patients before and after open heart surgery. Material and Methods: The data for the research was collected at the Department of Cardiovascular Surgery in Celal Bayar University Hafsa Sultan Hospital during the office hours through face-to-face interviews between January and June 2012. The study was carried out with 81 patients who were suitable and met the criteria. The data collection form included questions about socio-demographics, pain and disease, and the State-Trait Anxiety Inventory and Pain Distress Scale. The questionnaire was given to the patients 24 hours before the open heart surgery. The State-Trait Anxiety Inventory and Pain Distress Scale were administered to the same patients 48 hours after the surgery. _ Results: The average age of the participants was χ±SD=59.5±8.3. Most were male patients. There was no statistically significant difference between the average scores taken from the State-Trait Anxiety Inventory (t=0.6 p>0.05; t=1.0 p>0.05) before and after the surgery. It was observed before the surgery that there was a statistically significant relationship between the average scores taken from the Pain Distress Scale and the severity of pain (r=0.38 p<0.01). Also while statistically significant relationship was found between the average scores taken from the State-Trait Anxiety Inventory and Pain Distres Scale both before surgery (r=0.32 p<0.01; r=0.68 p<0.01) and after surgery (r=0.40 p<0.01; r=0.26 p<0.05). Conclusion: The results of the research show that anxiety, which is an emotional state or an individual characteristic, has an important role in pain perception. It is considered that the findings of the research will guide research into reducing the severity and distress of pain.
Effect of renal failure on N-terminal pro-brain natriuretic peptide in patients admitted to emergency department with acute dyspnea
(AVES Ibrahim Kara, 2014) Çolak A.; Çuhadar S.; Gölcük B.; Gölcük Y.; Özdoğan Ö.; Çoker B.
Objective: Preexisting renal failure diminishes the excretion of N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP), therefore limits the diagnostic value of this peptide for concomitant heart failure. The aim of this study was to evaluate the association between NT-proBNP and the stages of renal dysfunction in a typical population attended to emergency department with acute dyspnea.; Methods: In this cross-sectional study, all consecutive patients with acute dyspnea underwent clinical evaluation, laboratory assessment of NT-proBNP, and echocardiographic examinations. Among subjects, 54.5% were diagnosed as heart failure. Grouping variables according to renal function capacity and ejection fraction, independent variables were compared with Kruskal-Wallis or ANOVA with posthoc tests. Correlation and linear regression analysis were done to analyze the variables associated with NT-proBNP. The diagnostic performance of NT-proBNP was evaluated by receiver-operating characteristic (ROC) curve. ; Results: Serum median NT-proBNP level in patients with severe renal impairment was significantly higher than moderate and mildly decreased renal functions (p=0.001). In patients with moderate and severe left ventricular failure, NT-proBNP was significantly higher compared with normal subjects (LVEF>50%) (p=0.040, and 0.017, respectively). Renal dysfunction was associated in 56% of patients with heart failure. The area under the ROC curve of NT-proBNP for identifying left ventricular failure in patients with renal failure (eGFR<90 mL/min/1.73 m2) was 0.649 and reached significant difference (95% CI:0.548-0.749, p=0.005).; Conclusion: In addition to NT-proBNP measurement in clinical judgement of heart failure, renal functions have to be taken into consideration to avoid misdiagnosis. ©Copyright 2014 by Turkish Society of Cardiology.
Management of chronic hepatitis d virus infection: A consensus report of the study group for viral hepatitis of the turkish society of clinical microbiology and infectious diseases; [Kronik Hepatit D Virusu İnfeksiyonunun Yönetimi: Türk Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Derneği Viral Hepatit Çalışma Grubu Uzlaşı Raporu]
(AVES Ibrahim Kara, 2014) Ayaz C.; Yardımcı C.; Çandır N.; Ersöz G.; Şanlıdağ T.; Tığlı A.; Türken M.
Study Group for Viral Hepatitis of the Turkish Society of Clinical Microbiology and Infectious Diseases convened a meeting to develop a consensus report on management of chronic hepatitis D virus (HDV) infection, affecting nearly 5% of people infected with hepatitis B virus worldwide. Relevant literature and international guidelines were reviewed, and recommendations agreed are presented at the end of each section such as epidemiology, natural history and diagnosis of HDV infection, indications for treatment, treatment and follow-up, evaluation of response to treatment and long-term outcomes in HDV infection. Examples of some selected recommendations are as follows: [1] Patients with compensated liver disease, documented HDV viremia and elevated transaminase levels should be treated regardless of their liver histology. [2] Peg-IFN should be used for treatment of HDV infection. [3] Duration of therapy should be at least one year. [4] Treatment prolongation, provided that it can be tolerated, should be considered because of its potential benefit on virological response. [5] Although oral antivirals do not impact HDV replication, if they are needed to be used for HBV infection, a nucleotide analogue should be preferred to achieve a decline in HBsAg levels. Klimik Dergisi. © 2014, AVES Ibrahim Kara. All rights reserved.
The effect of long term continuous positive airway pressure treatment on systolic and diastolic function in patients with obstructive sleep apnoea syndrome: A five year observational study; [Obstrüktif uyku apne sendromlu hastalarda CPAP tedavisinin sistolik ve diyastolik sol ventrikül fonksiyonlari{dotless} üzerine etkisi; beş yi{dotless}lli{dotless}k takip çali{dotless}şmasi{dotless}]
(AVES Ibrahim Kara, 2014) Bilge A.R.; Yavuz V.; Çetin N.; Dalgiç O.; Kum G.; Yilmaz H.; Tikiz H.
Objective: Evaluation of the long term effects of continuous positive airway presure (CPAP) on mean heart rate and left ventricular systolic and diastolic parameters in obstructive sleep apnea syndrome (OSAS) using conventional and tissue Doppler techniques. Methods: This prospective cohort study is designed to evaluate the long term effects of CPAP treatments in normotensive OSAS patients. Initially 40 patients aged from eighteen to fifty five with documented OSAS syndrome were evaluated within one month of CPAP treatment. All had high self-reported compliance with treatment. From the latter, 21 patients with uninterrupted CPAP therapy (for at least 5 years, 5 hours per day) were included in the study and further evaluated with treatment. The left ventricular systolic function was assessed on apical four- chamber view using modified Simpson method and diastolic function was evaluated with classic transmitral pulsed and tissue Doppler techniques. Paired t test and Wilcoxon signed rank test had been used to compare the clinical and echocardiography data before and after treatment period. Results: A comparison of values assessed after one month and after 5 years of CPAP therapy, revealed a significant increase in the acceleration time(AT) Em/Am ratio and ejection time (ET) (AT: p=0.04; Em/Am ratio p=0.03 ET: p=0.04) while a significant decrease was observed on deceleration time (DT), isovolumetric relaxation time (IRT), myocardial performance index (MPI), mitral regurgitation (MR) and 24 hour mean heart rate (HR) in all subjects (DT: p=0.02; IVRT: p=0,04; MPI: p=0,01; MR: p≤0.001; HR: p=0.004). Conclusion: We observed a significant improvement in the left ventricular systolic and diastolic function and a significant decrease of 24-hour heart rate and mitral regurgitation with unchanged ejection fraction of the left ventricle with long term CPAP treatment similar to short-term treatment studies. The long term maintenance of the beneficial effect of CPAP throughout the 5 year long term treatment can be one of the pathophysiologic mechanisms that may explain the decrease of cardiovascular mortality observed with long term CPAP therapy in OSAS patients. © 2014 by Turkish Society of Cardiology.
Effects of high-dose rocuronium on the QTc interval during anaesthesia induction in patients undergoing coronary artery bypass graft surgery; [Koroner arter cerrahisi geçirecek olgularda anestezi İndüksiyonu sırasında yüksek doz roküronyumun QTc İntervali üzerine etkileri]
(AVES Ibrahim Kara, 2014) Ağdanlı D.; Öztürk T.; Ütük O.; Keleş G.T.
Objective: Existing myocardial damage in coronary artery disease patients causes prolonged QT syndrome. The primary objective of this trial is to explore the effects of different doses of muscle relaxant agent rocuronium (0.6 mg.kg−1 and 1.2 mg.kg −1) on QTc following anesthetic induction. Seconder objective is to determine the incidence and kinds of arrythmias.; Methods: In this prospective and randomized trial, patients undergo elective coronary arteria revascularisation surgery were included in one of two groups. Both groups took same anesthetic induction agents; midazolam and fentanyl. Rocuronium was administered in Group 1(n=20) with dose of 0.6 mg. kg−1 and in Group 2 (n=20) with dose of 1.2 mg.kg−1 for muscle relaxation.; Heart rate, avarage arteria pressure and QTc were recorded before induction(T0), after induction(T1), after muscle relaxant(T2), 2 minutes(T3) and 5 minutes after entubation(T4).; Results: QTc was significantly long just in 2 minutes after entubation (in Group 1 and Group 2 respectively, 447.9±28.3, 466.1±37.8ms), than those at the beginning (respectively, 426.9±25.7, 432.0±35.5ms)(p<.0.01). In intergroup comparison, avarage QTc values were similar in all trial periods (p>0.05). The prevalance of arrythmias in between Group 1 (35%, n=7), and Group 2 (15%, n=3) were similar (p=0.06). Arrythmias were recorded 2 minutes after entubation in both groups (n=10, 25%).; Conclusion: In patients undergoing coronary arteria revascularisation surgery, rocuronium doses of 0.6 mg kg −1 and 1.2 mg kg −1 had have prolonged the QTc interval after entubation. Cardiac arrthymias related to long QTc arising after entubation should be taken into consideration. © 2014 by Turkish Anaesthesiology and Intensive Care Society.
Toll-like receptor 2 expression and peripheral blood CD4+/CD8+ T cell ratio in COPD
(AVES Ibrahim Kara, 2014) Ulutaş G.Ş.; Alpaydin A.Ö.; Taneli F.; Çetinkaya C.; Ulman C.; Güvenç Y.; Horasan G.D.; Coşkun A.Ş.
OBJECTIVES: We aimed to evaluate toll-like receptor 2 (TLR-2) expression on monocytes and peripheral blood CD4+/CD8+ T cell ratio, as well as the relationship of these cells with pulmonary functions in chronic obstructive pulmonary disease (COPD) patients. MATERIAL AND METHODS: Forty COPD patients and 40 healthy volunteers were included. Participants were analysed in four groups according to their smoking status. Peripheral blood CD4+ and CD8+ T cells and monocyte TLR-2 expression were measured by flow cytometry in the whole study population. RESULTS: No significant difference was observed in TLR-2 expression, number of CD4+ and CD8+ T cells, and CD4+/CD8+ T cell ratio between the study groups. CD4+/CD8+ T cell ratio and FEV1/FVC were found to have a mild positive correlation (r=0.295, p=0.022). A mild negative correlation was observed between smoking intensity and CD4+/CD8+ T cell ratio (r=-0.274, p=0.034). CONCLUSION: We demonstrated a mild correlation between pulmonary functions and peripheral blood CD4+/CD8+ T cell ratio. However, we did not find a significant difference in TLR-2 expression of CD14+ monocytes in patients with airway obstruction. © 2014 by Turkish Thoracic Society.
Summary of consensus report on preoperative evaluation
(AVES Ibrahim Kara, 2015) Özkan M.; Coşkun F.
[No abstract available]
Stressors in the intensive care unit: Perceptions of patients and nurses; [Yoğun bakım Ünitesindeki stresörlerin hasta ve hemşireler tarafından algılanması]
(AVES Ibrahim Kara, 2015) Zaybak A.; Çevik K.
Objective: This study was conducted to investigate the perceptions of stressors in the intensive care unit by patients and nurses. Material and Methods: The research was performed in the medical and surgical intensive care units in a university hospital. The sample consisted of 86 patients who stayed in the intensive care units for at least 24 h, who were conscious, and who had no communication difficulties and 52 nurses who were working in the same intensive care units. A Patient and Nurse Description Form and an Intensive Care Unit Sources of Environmental Stress Scale (ICUSESS) were used to gather data. Results: The patients’ mean ICUSESS score was 80.65±18.46 and that of the nurses was 142.5±28.7. The nurses’ mean ICUSESS score was higher than that of the patients (t=15.063, p=0.00). Having an oral or nasal tube was the number one stressor reported by both patients and nurses. The other top fve stressors reported by the patients were lack of privacy, being in a very hot/cold room, men and women being in the same place, and hearing other patients cry and moan, whereas those of the nurses were feeling pain, fear of death, hearing the sound of a cardiac monitor which shows that there is a problem with the heart, and hearing other patients cry and moan. Conclusion: The level of perception of intensive care stressors by nurses was higher than that of the patients. The stressors perceived by the nurses and patients as the fve most important were similar, and it can also be said that the nurses mostly named the stressors relating to diseases, whereas the patients named those concerning the physical condition of intensive care. © 2015 by Turkish Society of Medical and Surgical Intensive Care Medicine.
COMET, TUNEL, and TEM analysis of an infertile male with short tail sperm
(AVES Ibrahim Kara, 2015) Durmaz A.; Mıçılı S.C.; Vatansever S.; Gündüz C.; Bağrıyanık H.A.; Dikmen N.; Tavmergen Göker E.N.; Tavmergen E.
Male infertility is correlated with sperm morphology and sperm DNA damage, which are completely different from that of fertile individuals. An accurate sperm DNA damage analysis and ultrastructural examination of the ejaculate provide important support in the clinical evaluation. It is supposed that in the near future, the fertilization rate, pregnancy rate, and miscarriages could be predicted using the combination of these types of tests in assisted reproductive technologies (ARTs). For this purpose, we report a very rare case of an infertile man having short tail sperm. The infertile man and his wife underwent in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI). During this process, we examined the ultrastructure of the ejaculated sperm with transmission electron microscopy (TEM) and calculated the sperm DNA damage with terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) and COMET assays. Then, we evaluated the association between sperm DNA damage and embryo quality. © 2015 by the Turkish-German Gynecological Education and Research Foundation.
Intravenous amantadine in percheron artery syndrome: Three cases; [Percheron Arter Sendromu'nda İntravenöz Amantadin: Üç Olgu]
(AVES Ibrahim Kara, 2015) Sarı Ü.; Kısabay A.; Boyacı R.; Oktan B.; Ovalı G.Y.; Tarhan S.; Yılmaz H.; Selçuki D.
Percheron artery syndrome is characterized by infarction at the paramedian nucleus of the thalamus and mesencephalon. Its classical triad comprises altered mental status with various clinical findings ranging from confusion to coma, restricted vertical gaze, and impaired memory. In this study, three cases of occlusion of the Percheron’s artery were presented along with their clinical and magnetic resonance findings. Their treatment additionally included infusion of amantadine, and its positive effect on the prognosis was assessed. © 2015 by Turkish Society of Medical and Surgical Intensive Care Medicine.
Assessment of experiences of patients discharged from intensive care units; [Yoğun Bakım Ünitesinden Taburcu olan Hastaların Yoğun Bakım Deneyimlerinin Değerlendirilmesi]
(AVES Ibrahim Kara, 2015) Adsay E.; Dedeli Ö.
Objective: The purpose of this study was to assess the experiences of patients discharged from intensive care units. Material and Methods: This descriptive and cross-sectional study was conducted with 190 patients who were hospitalized in intensive care units for 24 h and over in a university hospital and a public hospital in Manisa, Turkey. Data were collected by a demographic questionnaire and the Intensive Care Experience Scale. Mean±standard deviation, percentage, Pearson correlation coefficient, and Kruskal–Wallis and Mann–Whitney U tests were used in the statistical analysis. Results: The mean age of the patients was 56.6±10.8 years, and 60% of the patients were males. It was found that the patients’ awareness of the environment in the intensive care unit subscale score of the Intensive Care Experience Scale was significantly different depending on gender and the length of stay in the intensive care unit (p<0.05). It was found that the patients’ satisfactions levels about care the in intensive care unit subscale score of the Intensive Care Experience Scale was significantly difference depending on the type of intensive care unit and the length of stay in the intensive care unit (p<0.05). Conclusion: The results of this study show that being aware of the environment in intensive care unit was dependent the length of stay in the intensive care unit and gender and that satisfaction levels about care in the intensive care unit were affected by the length of stay in the intensive care unit and the type of intensive care unit. © 2015 by Turkish Society of Medical and Surgical Intensive Care Medicine.
The effect of flexible bronchoscopy on anxiety in children
(AVES Ibrahim Kara, 2016) Türkeli A.; Yılmaz Ö.; Topçu İ.; Yüksel H.
OBJECTIVES: Flexible bronchoscopy (FB) is a semi-invasive diagnostic tool that allows direct visualization of the airways. The use for diagnostic and therapeutic purposes in children is incrasing with the developments in modern anesthesia. Irrespective of the type of the invasive diagnostic procedure, these interventions are known to cause anxiety in patients. The aim of our study was to evaluate the anxiety and depression status in children hospitalized for bronchoscopy and to investigate the effects of FB. MATERIAL AND METHODS: Thirty children hospitalized for FB and 30 controls, aged 7 to16 years, were enrolled in this study. Anxiety was evaluated with the "Hospital anxiety and depression scale" (HADS)" besides other parameters recorded. RESULTS: The mean HADS anxiety scores in the patient and control groups were respectively 10.1 (3.5) and 2.7 (1.3) (p= 0.001). The mean HADS depression scores were respectively 8.8 (3.7) and 2.2 (1.1) (p= 0.001). Among the patients, 50% had anxiety and 53.3% had findings while none in the control group showed signs of anxiety and depression. A positive correlation was found between the age and, anxiety and depression scores in patients’ groups (respectively r1= 0.257; p= 0.05 and r2= 0.288; p= 0.02). CONCLUSION: Anxiety was demonstrated in nearly half of the children hospitalized for bronchoscopy. It has been observed that behavioral and physical problems may be encountered in approximately 40-60% of children who feel generalized anxiety before anesthesia, during the preoperative, postoperative period, and subsequent periods. These results suggest that the detection of children with increased anxiety and indicate the individual requirements can be assisted pharmacological and psychological supports. © 2016 by Turkish Thoracic Society.
Predictive and prognostic factors in ovarian and uterine carcinosarcomas
(AVES Ibrahim Kara, 2016) Cicin İ.; Özatlı T.; Türkmen E.; Özturk T.; Özçelik M.; Çabuk D.; Gökdurnalı A.; Balvan Ö.; Yıldız Y.; Şeker M.; Özdemir N.; Yapar B.; Tanrıverdi Ö.; Günaydin Y.; Menekşe S.; Öksüzoğlu B.; Aksoy A.; Erdogan B.; Hacıoglu M.B.; Arpaci E.; Sevinç A.
Background: Prognostic factors and the standard treatment approach for gynaecological carcinosarcomas have not yet been clearly defined. Although carcinosarcomas are more aggressive than pure epithelial tumours, they are treated similarly. Serous/clear cell and endometrioid components may be predictive factors for the efficacy of adjuvant chemotherapy (CT) or radiotherapy (RT) or RT in patients with uterine and ovarian carcinosarcomas. Heterologous carcinosarcomas may benefit more from adjuvant CT. Aims: We aimed to define the prognostic and predictive factors associated with treatment options in ovarian (OCS) and uterine carcinosarcoma (UCS). Study Design: Retrospective cross-sectional study Methods: We retrospectively reviewed the medical records of patients with ovarian and uterine carcinosarcoma from 2000 to 2013, and 127 women were includ ed in this study (24 ovarian and 103 uterine). Patients admitted to seventeen oncology centres in Turkey between 2000 and December 2013 with a histologically proven diagnosis of uterine carcinosarcoma with FIGO 2009 stage I-III and patients with sufficient data obtained from well-kept medical records were included in this study. Stage IV tumours were excluded. The patient records were retrospectively reviewed. Data from 104 patients were evaluated for this study. Results: Age (≥70 years) was a poor prognostic factor for UCS (p=0.036). Pelvic±para aortic lymph node dissection did not affect overall survival (OS) (p=0.35). Macroscopic residual disease was related with OS (p<0.01). The median OS was significantly longer in stage I-II patients than stage III patients (p=0.03). Adjuvant treatment improved OS (p=0.013). Adjuvant radiotherapy tended to increase the median OS (p=0.075). However, this tendency was observed in UCS (p=0.08) rather than OCS (p=0.6).Adjuvant chemotherapy had no effect on OS (p=0.15).Adjuvant radiotherapy significantly prolonged the median OS in patients with endometrioid component (p=0.034). A serous/clear cell component was a negative prognostic factor (p=0.035). Patients with serous/clear cell histology for whom adjuvant chemotherapy was applied had significantly longer OS (p=0.019), and there was no beneficial effect of adjuvant radiotherapy (p=0.4). Adjuvant chemotherapy was effective in heterologous tumours (p=0.026). In multivariate analysis, the stage and chemotherapy were prognostic factors for all patients. Age was an independent prognostic factor for UCS. However, serous/clear cell histology and radiotherapy tended to be significant prognostic factors. Conclusion: The primary location, the histological type of sarcomatous and the epithelial component may be predictive factors for the efficacy of chemotherapy or radiotherapy in UCS and OCS. © Trakya University Faculty of Medicine.
Molecular epidemiology of hepatitis B virus; [Hepatit B virusunun moleküler epidemiyolojisi]
(AVES Ibrahim Kara, 2016) Arıkan A.; Şanlıdağ T.
In addition to high viral copy number during replication, HBV reverse transciptase also does not have a proofreading function, therefore, many HBV genotypes, subgenotypes, mutants and recombinants can emerge. To date, 10 HBV genotypes (A-J) and almost 40 subgenotypes have been identified. Genotype A is dominant in Northwest Europe, North America and Africa; genotype B and C are common in Asian countries; genotype C is more dominant in East and Southeast Asian countries. Genotype D is widespread in the whole world and is endemic in the Meditteranean area, the Middle East and Western Asia. Genotype E is dominant in Western Africa and genotype H has been found in Central and South America. Genotype G has been reported in France, Germany and America. The genotype H is found in Central America. Recently identified genotype I, a recombination of genotypes A, C and G, was isolated in Vietnam and Laos. The most recent genotype J was identified in the Ryukyu islands in Japan and this genotype has a relationship between gibon/ orangutan genotypes and human genotype C. In this review, HBV genotypes and subgenotypes, their geographic distributions and clinical aspects were overviewed. © 2016 AVES Ibrahim Kara. All rights reserved.
The effect of a training program on oral health and behavior change in asthma patients
(AVES Ibrahim Kara, 2016) Taşkın Yılmaz F.; Çınar S.; Yılmaz A.; Karakoç Kumsar A.
Background: Asthma is a chronic disease which is prevalent throughout the world. Physical problems such as deterioration in oral health, which may occur due to the triggering factors of asthma as well as the ineffective use of asthma medicine, seem to affect the daily lives of asthma patients. Therefore, it is important to protect oral health and promote positive behavior changes in asthma patients in order to achieve effective treatment and asthma control. Aims: The present study aimed to determine the effects of a training program provided for asthma patients on oral health, inhaler use skills, and behavior change. Study Design: Controlled experimental study. Methods: A total of 124 asthma patients were included in the study. Of the patients, 62 were assigned to the experimental group and the other 62 were assigned to the control group. Data were collected using the patient identification form, the oral assessment guide, the inhaler use skill form, and the evaluation form for behavior change over time. The experimental group received training provided by the researchers on the first meeting and one month later. Written and visual training material were used. Both groups were subject to a final evaluation which was conducted 4 months after their first meeting. Results: It was determined that the oral assessment guide scores (p<0.01) and inhaler use skills of the experimental group improved significantly after the training compared to the control group (p<0.01). In addition, it was observed that the number of patients in the experimental group who quit smoking (p<0.05), used their medicine (p<0.01) and brushed their teeth on a regular basis (p<0.01), and washed their mouth after inhaler use significantly increased in the experimental group after training compared to the control group (p<0.01). Conclusion: The study demonstrated that the training provided for asthma patients improved oral health and promoted inhaler use skills and was partially effective in promoting positive asthma-related behavior change. © Trakya University Faculty of Medicine.
Assessment of bladder wall thickness in women with overactive bladder
(AVES Ibrahim Kara, 2016) Üçer O.; Gümüş B.; Albaz A.C.; Pekindil G.
Objective: To compare bladder wall thickness (BWT) between female patients with overactive bladder (OAB) and aged-matched healthy controls. Material and methods: Thirty-six female patients with OAB and 31 healthy women were enrolled in the present prospective observational study. Qmax and Qave were measured by using uroflowmetry in all of the women in the patient and control groups, and also maximum bladder capacity (MBC), post- void residual urine (PVRU), prevoiding and postvoiding BWT were measured by using transabdominal ultrasound. Lower urinary tract symptoms of the participants were assessed by using Overactive Bladder Version-8 (OABV8) and International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF). All of the data were statistically compared between the patient and control groups. In the patient group, the relationships between parameters were evaluated correlation analysis. Results: The mean age of the patients and controls were similar (respectively, 45.58±12.35 and 44.21±11.60 years (p=0.68). The mean pre- and post-voiding BWT, OAB-V8 and ICIQ-SF scores of the patients were significantly higher than the controls. In the patient group, the moderate positive correlations between BWT with Qmax (p=0.02) and Qave (p=0.02) were found. Conclusion: This study showed that the BWTs of the female patients with OAB are higher than those of healthy women. Further studies should investigate the changes in BWT of patients with OAB after treatment of OAB. © 2016 by Turkish Association of Urology.
The efficacy of femoral block and unilateral spinal anaesthesia on analgesia, haemodynamics and mobilization in patients undergoing endovenous ablation in the lower extremity; [Alt ekstremitede endovenöz ablasyon uygulanan olgularda femoral sinir bloğu ve tek taraflı spinal bloğun analjezi, hemodinami ve mobilizasyon üzerine etkileri]
(AVES Ibrahim Kara, 2016) Öztürk T.; Çevikkalp E.; Nizamoglu F.; Özbakkaloğlu A.; Topcu İ.
Objective: This study aimed to investigate the efficacy of femoral block and unilateral spinal anaesthesia on analgesia, haemodynamics and mobilization during endovenous ablation in patients with lower extremity venous insufficiency. Methods: Forty patients of ASA physical status I and II, with ages ranging between 30 and 45 years, and who were scheduled for endovenous laser ablation for varicose veins were prospectively enrolled in this study. Patients were randomized into a unilateral spinal anaesthesia group (group HS, n=20) or a femoral block group (group F, n=20). Group HS received 7.5–10 mg of heavy bupivacaine for unilateral spinal anaesthesia, while group F received 100 mg prilocaine for femoral block with ultrasound guidance. The level of motor blockage (Bromage score), visual pain score, mean heart rate and mean arterial pressures were recorded at postoperative 0, 1, 2, 3d and 6 h, respectively. Results: Perioperative visual pain score values in both groups were <4. None of the groups required an additional analgesic agent. Bromage scores were significantly lower in group F than in group HS during the postoperative period (p<0.01). Motor function returned to normal in all patients at 3 h in group F and at 6 h in group HS. Postoperative mean heart rate and arterial pressure did not differ between the groups (p>0.05). Conclusion: In patients with lower extremity venous insufficiency who were undergoing endovenous laser ablation, an ultrasound-guided femoral block provided similar analgesia with that of unilateral spinal anaesthesia. In group F, the duration of anaesthesia and mobilization time was shorter. © 2016 by Turkish Anaesthesiology and Intensive Care Society.
Comparison of patient satisfaction between general and spinal anaesthesia in emergency caesarean deliveries; [Acil sezaryen operasyonlarında genel ve spinal anestezinin hasta memnuniyeti yönünden karşılaştırılması]
(AVES Ibrahim Kara, 2017) Açıkel A.; Öztürk T.; Göker A.; Hayran G.G.; Keleş G.T.
Objective: Obstetric anaesthesia aims to deliver a healthy baby as well as render a comfortable operation for the mother. This study compared general and spinal anaesthesia in terms of the quality of recovery and patient satisfaction in women undergoing emergency caesarean deliveries. Methods: In total, 100 patients were enrolled in this prospective, single-blind, cross-sectional clinical study. Patients were divided into spinal (n=50) and general (n=50) anaesthesia groups. The recovery score, pain and satisfaction were evaluated by Quality of Recovery Score (QoR-40), Visual Analogue Scale (VAS) and Numeric Rating Scale (NRS) at 24 hours postoperatively. Results: The total QoR-40 scores were significantly higher and the total operation time was longer in the spinal anaesthesia group (median score: 194.5 vs. 179.0, p<0.001 and mean±SD: 69.0±13.3 vs. 62.7±13.4 minutes, p=0.02, respectively). There was no significant difference in VAS and NRS scores between the groups. Conclusion: Both spinal anaesthesia and general anaesthesia have advantages and disadvantages in terms of emergency caesarean deliveries. Spinal anaesthesia speeds up the recovery time and enables the mother to return to normal life earlier, while general anaesthesia has a short initiation time and does not affect patient satisfaction. © 2017 by Turkish Anaesthesiology and Intensive Care Society.

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