Browsing by Publisher "Baycinar Medical Publishing"

Now showing 1 - 7 of 7
  • No Thumbnail Available
    Item
    Comparison of amiodarone and propafenone for maintenance of stable sinus rhythm after bipolar radiofrequency ablation combined with a mitral valve procedure in patients with mitral valve disease and persistent atrial fibrillation
    (Baycinar Medical Publishing, 2015) Beşir Y.; Gökalp O.; Yetkin U.; Çelik E.; Iner H.; Lafçi B.; Tetik O.; Gürbüz A.
    Background: This study aims to examine the effects of amiodarone versus propafenone for maintenance of stable sinus rhythm after left atrial bipolar radiofrequency ablation combined with a mitral valve procedure in patients with mitral valve disease and persistent atrial fibrillation. Methods: The study included 75 patients (29 males, 46 females; mean age 66,8±7.4 years; range 54 to 82 years) who underwent left atrial bipolar radiofrequency ablation combined with mitral valve surgery between July 2008 and July 2010. Patients were divided into three groups of 25: propafenone group (group 1), amiodarone group (group 2), and control group (group 3). Atrial fibrillation patients with slow ventricular response were excluded from the study. Results: Data was collected at preoperative period, during surgery, prior to discharge from hospital, and at 3, 6, and 18 months after discharge. Patients from all groups were followed for 18 months. In group 1, the number of patients in sinus rhythm was 22 at discharge, 20 at three months, and 21 at six and 18 months. In group 2, the number of patients in sinus rhythm was 18 at discharge, 13 at three months, 15 at six months, and 16 at 18 months. In group 3, the number of patients in sinus rhythm was 16 at discharge, 11 at three months, 12 at six months, and 14 at 18 months. Group 1 had a statistically significantly higher rate of stable sinus rhythm. No hospital mortality was observed in any group. Conclusion: This study revealed that propafenone was more effective than amiodarone in maintenance of stable sinus rhythm at the postoperative period in patients who underwent bipolar radiofrequency ablation combined with a mitral valve procedure.
  • No Thumbnail Available
    Item
    A thymic neuroendocrine carcinoma presenting with upper gastrointestinal bleeding: A case report
    (Baycinar Medical Publishing, 2017) Yaldiz S.; Yaldiz D.; Tulay C.M.; Işisağ A.
    Neuroendocrine carcinomas of the thymus are rare clinical entities, which can be complicated by endocrine abnormalities. These tumors are frequently associated with ectopic adrenocorticotropic hormone production giving rise to Cushing's syndrome. Herein, we describe a 23-year-old male case with upper gastrointestinal bleeding as the initial presentation of a thymic neuroendocrine carcinoma. This case was reported due to its extremely exceptional occurrence. © 2017 All right reserved by the Turkish Society of Cardiovascular Surgery.
  • No Thumbnail Available
    Item
    Papillary predominant histological subtype predicts poor survival in lung adenocarcinoma
    (Baycinar Medical Publishing, 2019) Yaldiz D.; Acar A.; Kaya S.Ö.; Aydoğdu Z.; Gürsoy S.; Yaldiz S.
    Background: This study aims to investigate whether papillary predominant histological subtype can predict poor survival in lung adenocarcinoma. Methods: Between January 2005 and December 2016, a total of 80 patients with papillary predominant subtype lung adenocarcinoma (70 males, 10 females; mean age 60.7 years; range, 42 to 79 years) operated in our clinic were included in the study. These patients were compared with those having lepidic, acinar, and mucinous subtypes. Overall and five-year survival rates were evaluated. Results: Five-year survival was 40.5% in papillary predominant histological subtype, while this rate was 70.9%, 59.0%, and 66.6% in lepidic, acinar, and mucinous subtypes, respectively. Papillary subtype showed significantly poor survival compared to lepidic (p=0.002), acinar (p=0.008), and mucinous subtypes (p=0.048). In Stage 1 disease, it was more evident (papillary, 47.5%, lepidic 86.9% [p=0.001], acinar 69.3% [p=0.040], and mucinous 90.0% [p=0.050]). Conclusion: Our study results suggest that papillary predominant subtype predicts poor survival in lung adenocarcinoma and these cases may be candidates for adjuvant treatment modalities even in the earlier stages of disease. © 2019 Turkish Society of Cardiovascular Surgery.
  • No Thumbnail Available
    Item
    How important is the damage to the liver after lower limb ischemia-reperfusion? An experimental study in a rat model
    (Baycinar Medical Publishing, 2020) Gökalp G.; Eygi B.; Kiray M.; Açikgöz B.; Berksoy E.; Bicilioğlu Y.; Zengin N.; Işcan S.; Gökalp O.; Gürbüz A.
    Background: The aim of this study was to compare the effect of lower extremity ischemia reperfusion on the liver and the effect of ischemiareperfusion on the liver itself in a rat model. Methods: Thirty Sprague-Dawley male rats were randomly divided into three groups including 10 in each group: sham (Group 1), lower limb ischemia-reperfusion (Group 2), and liver ischemia-reperfusion (Group 3). In Group 2, one hour of left lower limb ischemia was performed. In Group 3, one hour of ischemia in the liver was performed, followed by 24 hours of reperfusion. After reperfusion, the liver tissues were removed, and the groups were evaluated biochemically and histologically. Results: The liver malondialdehyde levels were significantly higher in Groups 2 and 3 than in the sham group (p<0.001). In Group 2, the malondialdehyde levels were significantly higher than in Group 3 (p=0.019). The glutathione levels in the liver were significantly lower in Groups 2 and 3 than in the sham group (p<0.001). However, the glutathione levels were significantly higher in Group 2 than in Group 3 (p=0.005). In the histological evaluation, although the liver damage score was higher in Group 3 than in Group 2 (p=0.015), there was no significant difference between the two groups in TUNEL(+) cell number (p>0.05). Conclusion: Reperfusion injury in the liver after lower limb ischemiareperfusion is as important as ischemia-reperfusion injury which is specifically induced in the liver. This should be taken into account, particularly in reperfusion surgeries following vascular trauma or in cases of leg tourniquets to stop bleeding after lower limb vascular trauma. © 2020 All right reserved by the Turkish Society of Cardiovascular Surgery.
  • No Thumbnail Available
    Item
    Langerhans cell histiocytosis: A rare cause of pathological rib fracture
    (Baycinar Medical Publishing, 2021) Yolcu A.; Tulay C.M.; Temiz P.; Aydoğdu İ.
    Langerhans cell histiocytosis, formerly known as histiocytosis X, represents clonal proliferations of the antigen-presenting dendritic cells, which are normally found in many organs. It is a rare disease which tends to affect children and adolescents. In particular, adult-onset type is very rare. Herein, we present a female adult diagnosed with Langerhans cell histiocytosis of the rib without any systemic involvement which was successfully treated with surgery. © 2021. All right reserved by the Turkish Society of Cardiovascular Surgery.
  • No Thumbnail Available
    Item
    Genes predisposing tunneled catheter thrombosis in hemodialysis patients; [Hemodiyaliz hastalarında tünelli kateter trombozuna yol açan genler]
    (Baycinar Medical Publishing, 2022) Senarslan D.A.; Gümüş A.A.; Cam F.S.; Kurdal A.T.
    Background: This study aims to investigate the association of genes predisposing thrombophilia with tunneled catheter thrombosis in hemodialysis patients. Methods: Between October 2018 and December 2020, we compared the frequencies of genetic polymorphisms causing thrombophilia, including prothrombin G20210A, factor V Leiden, methylene tetrahydrofolate reductase (MTHFR) C677T, MTHFR A1298C, plasminogen activator inhibitor (PAI), factor XIII V34L and clinical characteristics of 52 patients with a history of ≥2 tunneled catheter thrombosis occlusions within a year (Group 1; 24 males, 28 females; mean age: 62±8.9 years; range, 45 to 77 years), 52 patients who underwent their first tunneled catheter thrombosis insertion (Group 2; 29 males, 23 females; mean age: 63±15.2 years; range, 22 to 87 years), and 51 healthy controls (Group 3; 26 males, 25 females; mean age: 34±9.2 years; range, 19 to 54 years). Results: Groups 1 and 2 carried the MTHFR A1298C (p=0.048) and compound heterozygous MTHFR A1298C and C677T (p=0.048) polymorphisms more frequently than Group 3. However, subgroup analysis results were not statistically significant. The other polymorphisms were distributed similarly in all three groups. The MTHFR polymorphisms had a weak effect on tunneled hemodialysis catheter thrombosis in neural network analysis. Conclusion: Our study results indicated that there was a concomitance of MTHFR polymorphisms with hemodialysis-dependent chronic kidney disease. The MTHFR A1298C and compound heterozygous MTHFR polymorphisms may be associated with tunneled hemodialysis catheter thrombosis. Thrombophilia gene screening may be recommended in hemodialysis patients undergoing tunneled hemodialysis catheter thrombosis at least twice in a year. © 2022 All right reserved by the Turkish Society of Cardiovascular Surgery. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes (http://creativecommons.org/licenses/by-nc/4.0/).
  • No Thumbnail Available
    Item
    The effects of perioperative goal-directed therapy on acute kidney injury after cardiac surgery in the early period; [Perioperatif hedefe yönelik tedavinin kardiyak cerrahi sonrası erken dönem akut böbrek hasarı üzerine etkileri]
    (Baycinar Medical Publishing, 2023) Özdemir İ.; Öztürk T.; Amanvermez D.; Yıldırım F.; Şengel A.; Özdemir İ.H.
    Background: This study aims to investigate the effects of goaldirected fluid therapy on the development of acute kidney injury in the perioperative period in patients undergoing cardiopulmonary bypass. Methods: Between November 2019 and May 2021, a total of 60 patients (46 males, 14 females; mean age: 62.5±9.6 years; range, 44 to 76 years) who were scheduled for elective coronary artery bypass grafting or valve surgery under cardiopulmonary bypass were included in the study. The patients were divided into two groups as the study group (Group S, n=30) and control group (Group C, n=30). The patients in Group C were treated with standard therapy, while the patients in Group S were treated with goal-directed fluid therapy. The Kidney Disease: Improving Global Outcomes (KDIGO) classification and renal biomarkers were used for the evaluation of acute kidney injury. Results: Acute kidney injury rates were similar in both groups (30%). Postoperative fluid requirement, intra-, and postoperative erythrocyte suspension requirements were significantly lower in Group S than Group C (p=0.002, p=0.02, and p=0.002, respectively). Cystatin-C was lower in Group S (p<0.002). The kidney injury molecule-1, glomerular filtration rate, and creatinine levels were similar in both groups. The length of hospital stay was longer in Group C than Group S (p<0.001). Conclusion: Although goal-directed fluid therapy does not change the incidence of acute kidney injury in patients undergoing cardiac surgery, it can significantly decrease Cystatin-C levels. Goal-directed fluid therapy can also decrease fluid and erythrocyte requirements with shorter length of hospital stay. © 2023 All right reserved by the Turkish Society of Cardiovascular Surgery.