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  1. Home
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Browsing by Publisher "CSIRO"

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    Tin and mercury compounds supported by a bulky organometallic ligand incorporating a pendant guanidine functionality
    (CSIRO, 2014) El-Hamruni S.M.; Sözerli S.E.; Smith J.D.; Coles M.P.; Hitchcock P.B.
    The structure of a triclinic form of the organolithium derivative LiR, R≤C(SiMe3)2(SiMe2{hpp}) (1) (hppH≤1,3,4,6,7,8,-hexahydro-2H-pyrimido[1,2- a]pyrimidine) comprises dimers [1]2 held together by Li··· H3C interactions like those in the polymeric structure [1]∞ of the previously described orthorhombic form. Compound 1 reacts with the chlorides MCl2 (M≤Hg or Sn) to give compounds HgRCl (2) or SnRCl (3), which have been characterised by NMR spectroscopy and X-ray crystallography. The structural parameters and conformations of the metallacycles MRLn are compared with those in related compounds containing bulky organosilicon ligands with pendant nitrogen donors. Compound 3 reacts with Li[P{H}Ar*] (Ar*≤2,4,6- tBu3C6H2) to give the crowded phosphanide SnR(P{H}Ar*) (4). © CSIRO 2014.
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    Factors affecting the views and experiences of women living in the city centre of Manisa, Turkey, regarding domestic violence
    (CSIRO, 2016) Özpinar S.; Horasan G.D.; Baydur H.; Canbay T.
    Domestic violence against women is an important social and public health problem worldwide resulting from unequal power relationships between men and women. The purpose of the present cross-sectional descriptive study was to determine the factors affecting the views and experiences of women living in the city centre of Manisa, Turkey, regarding domestic violence. The data were collected from a representative sample of women (n≤873) in 2012. The socio-demographic questionnaire and the World Health Organization's Multi-country Study on Women's Health and Domestic Violence Against Women were used for data collection. The study results revealed that of the women, 14.8% were exposed to physical violence, 7.9% to sexual violence, 20.2% to emotional violence/abuse and 11.2% to economic violence/abuse within the last 12 months. Lower income level, lower social status, lower educational level, unemployment, being exposed to parental violence during childhood and being married to husbands exposed to parental violence during childhood were associated risk factors with domestic violence. The study results indicate that domestic violence against women is a common phenomenon in Manisa. © La Trobe University 2016.
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    Effect of kisspeptin-54 on ovarian levels of pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in an experimental model of ovarian hyperstimulation syndrome (OHSS)
    (CSIRO, 2021) Birinci H.; Vatansever H.S.; Yüncü M.
    The purpose of this study was to investigate the effect of kisspeptin-54 on ovarian morphology and vascular endothelial growth factor (VEGF), pigment epithelium-derived factor (PEDF), protein kinase A (PKA) and protein kinase C (PKC) levels in an ovarian hyperstimulation syndrome (OHSS) rat model, which is a possible complication of controlled ovarian hyperstimulation. For this purpose, immature female Sprague-Dawley rats (25 days old, 30-40 g) were randomly divided into five groups (control, sham, OHSS model, short-term kisspeptin-54 administered OHSS model and long-term kisspeptin-54 administered OHSS model). Serum LH and FSH levels were determined by enzyme-linked immunosorbent assay. Immunohistochemistry and quantitative RT-PCR were performed for VEGF, PEDF, PKA and PKC in ovaries and granulosa cells, respectively. It was observed that there was dilatation in fallopian tubes and an abnormal increase in ovarian weight and volume in the OHSS group, and these morphologies decreased with kisspeptin-54 treatment. After the administration of kisspeptin-54 in the OHSS group, VEGF, PKA and PKC levels reduced and PEDF levels increased in both mRNA and protein levels. It was determined that in the OHSS model, VEGF increased as PEDF decreased, and kisspeptin-54 reduced the effects of OHSS. It was determined that long-term kisspeptin-54 treatment was more effective than short-term administration. It is considered that kisspeptin-54 is an agent that protects ovarian reserve and oocyte maturation in women at risk of OHSS. © 20212021TheAuthor(s)(ortheiremployer(s)).PublishedbyCSIROPublishing.; RD21140_toc.jpg © 2021

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