Browsing by Publisher "Ekin Tibbi Yayincilik"

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Factors affecting the quality of life in climacteric women in Manisa region; [Manisa bölgesinde yaşayan klimakterik dönem kadınlarında yaşam kalitesini etkileyen faktörler]
    (Ekin Tibbi Yayincilik, 2010) Inceboz Ü.; Demirci H.; Özbaşaran F.; Çoban A.; Nehir S.
    Objectives: To determine the factors affecting the severity of menopausal symptoms and the quality of life among women living in Manisa, a western city of Turkey. Patients and Methods: After statistical estimation of the sample size reflecting the whole population, 268 climacteric women (mean age 50.7±6.6 years; range 40 to 60 years) with menopausal symptoms were investigated by sociodemographic questionnaire, menopause rating scale (MRS), and Quality of Life Scale (WHOQOL-BREF-TR) in Celal Bayar University Hospital. Results: Almost 1/3 of women had no knowledge on menopause. The MRS scores of women were inversely correlated with Physical Health, Psychological well-being, Social Relationship domains of quality of life. Educational level, menopausal knowledge, participation in decision-making in the family and economic status positively affected most domains of quality of life, whereas being married and having high BMI scores had negative effects. Conclusion: In climacteric women, quality of life was negatively affected by the severity of menopausal symptoms, low education level, limited menopausal knowledge, and being overweight. © Medical Journal of Trakya University.
  • No Thumbnail Available
    Item
    Gastric metastasis of merkel cell carcinoma: Case report; [Midede merkel hücreli karsinom metastazı: Olgu sunumu]
    (Ekin Tibbi Yayincilik, 2010) Temiz P.; Ayhan S.; Adigüzel L.; Kara E.; Okçu G.
    Merkel cell carcinoma (MCC) of skin is a rare tumor with aggressive behavior. Local recurrences, regional lymph node and distant metastases of MCC are frequent but to date metastasis to upper gastrointestinal tract was reported only a few. We present a 75-yearold man who had primary MCC at his left thigh. The tumor was excised and the patient was directed to local radiotherapy. He had developed abdominal and thoracal subcutaneous metastatic nodules within 5 and 8 months after surgical excision, respectively. In the tenth month, a second operation had to be performed because of a perforated duodenal ulcer and incidentally a submucosal yellow-white nodule measuring 2 cm in diameter was found in the wall of gastric cardia and excised. This lesion was histologically identical to the primary tumor, hence, gastric metastasis of MCC. The patient rejected further therapy and died 17 months after the initial diagnosis. Differential diagnosis of MCC and distinction of gastrointestinal MCC metastasis from primary neuroendocrine tumors may be difficult. Clinical information and histopathological features along with the results of immunohistochemical stainings are very important in this distinction. © Medical Journal of Trakya University. Published by Ekin Medical Publishing. All rights reserved.
  • No Thumbnail Available
    Item
    Primary squamous cell carcinoma of the breast: A case report and immunohistochemical features for differential diagnosis; [Memenin primer skuamöz hücreli karsinomu: Olgu sunumu ve Ayırıcı tanı açı;sından İmmunohistokimyasal özellikleri]
    (Ekin Tibbi Yayincilik, 2010) Temiz P.; Kandiloǧlu A.R.; Şimşek G.; Coşkun T.; Göktan C.
    We present a 68-year-old postmenopausal woman with a rapidly growing right breast mass. It was diagnosed as "invasive ductal carcinoma" on tru-cut biopsy owing to infiltrative pattern and c-erbB-2 (HER2/neu) and progesterone receptor positivities. Partial response was obtained after four cure chemotherapy (adriamycin and cyclophosphamide). Then, she underwent a modified radical mastectomy with axillary lymph node dissection (level III). Grossly, a white-tan, solid, ill-defined tumor with 5 cm diameter located in the upper inner and outer quadrant of the breast was detected. Central portion of the tumor showed necrotic and hemorrhagic changes. Microscopic examination revealed poorly differentiated squamous cell carcinoma (SCC) having intraductal epithelial hyperplasia with squamous cell metaplasia and multiple small tumor foci at the periphery. The tumor had patchy necrotic, hemorrhagic and fibrotic areas representing regressive changes due to chemotherapy effect. Immunohistochemically, the tumor stained diffusely with CK7, CK8, CK19, HMW-CK and E-cadherin, whereas focally with CEA. Estrogenand progesterone receptors and c-erbB-2 were negative in the tumor. Five out of 20 lymph nodes dissected from the specimen were metastatic. Clinically, other organs were ruled out as the originating site of the tumor. She had taken oral chemotherapy (capecitabine) after surgery and has been living healthy for one year. © Medical Journal of Trakya University.