Browsing by Publisher "Ortadogu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S."

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    Retrospective Evaluation of Patients Diagnosed with Clinically and Histopathologically Non-Infectious Granulomatous Dermatitis: 17-Year Single Center Experience; [Klinik ve Histopatolojik Olarak Enfeksiyöz Olmayan Granülomatöz Dermatit Tanısı Almış Olguların Retrospektif Olarak Değerlendirilmesi: 17 Yıllık Tek Merkez Deneyimi]
    (Ortadogu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2024) Çetınarslan T.; Masat A.K.; Temız P.; Türel Ermertcan A.
    Objective: Granulomatous dermatitis (GD) is a group of diseases grouped under two main headings: infectious and non-infectious, characterized histopathologically by granulomas and may also present with systemic findings. Granulomatous inflammation may be limited to the skin only or may occur as a symptom of a systemic disease. Material and Methods: 105 patients included who were clinically and histopathologically diagnosed with non-infectious GD in our clinic between 2006 and 2023. Results: Of the 105 patients included in our study, 79 were female and 26 were male. The mean age of the patients was 45.72 (age range 2-77). While 12 of the patients were under the age of 18, 12 patients were over the age of 65. The diagnosis of the patients were granuloma annulare (n=43), followed by sarcoidosis (n=24), necrobiosis lipoidica (n=12), interstitial GD (n=6), granulomatous rosacea (n=5), panniculitis (n=5), granuloma fasciale (n=2), Crohn’s disease (n=2), granulomatous vasculitis (n=2), piyoderma gangrenozum (n=1), post herpetic GD (n=1), lupus miliaris disseminatus faciei (n=1), granulomatous mycosis fungoides (n=1) and elastolytic giant cell granuloma (n=1). Conclusion: GDs are a heterogeneous group of diseases with varying clinical and histopathological findings. Histopathological morphology alone is rarely specific and is not sufficient to make a definitive diagnosis of the disease that plays a role in etiology. Conclusion: Differential diagnosis of GDs should be made in the light of histopathological findings, microbiological examination and clinical data. © 2024 by Türkiye Klinikleri.
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    A Case of Multiple Bilateral Facial Isolated Cutaneous Angiofibromas with Clinical, Genetic, Histopathological and Dermoscopic Findings; [Klinik, Genetik, Histopatolojik ve Dermoskopik Bulguları ile Bilateral Yüz Yerleşimli İzole Multipl Kutanöz Anjiyofibrom Olgusu]
    (Ortadogu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2024) Çeti̇narslan T.; Üstüntaş R.; Altiner Ş.; Türel Ermertcan A.; Temi̇z P.; Şahi̇n M.T.
    Cutaneous angiofibroma is a group of lesions that show similar histological features, but different clinical findings and can be divided into four subgroups: fibrous papule, adenoma sebaceum, periungual fibroma (Koenen tumors) and pearly penile papules of the penis. Facial angiofibromas are one of the diagnostic clinical findings of tuberous sclerosis. Although less common, it has also been reported in cases with multiple endocrine neoplasia Type 1, Birt-Hogg-Dubé syndrome, neurofibromatosis Type 2 and Cowden syndrome. It may also occur isolated without accompanying any systemic syndrome, as in our case. There is a report of four cases with bilateral multiple facial cutaneous angiofibromas that are not accompanied by any syndrome, and no other publication has been found in the literature. In this report, a twelve-year-old male patient with bilateral facial cutaneous angiofibromas, unaccompanied by systemic findings, is presented with its clinical, genetic, dermoscopical and histopathological findings. Copyright © 2024 by Türkiye Klinikleri.
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    Unveiling the Power of Nailfold Dermoscopy: Staging Raynaud’s Phenomenon: Case Control Research; [Tırnak Kıvrımı Dermoskopisinin Gücünü Ortaya Çıkarmak: Raynaud Fenomenini Evreleme: Olgu Kontrol Araştırması]
    (Ortadogu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2024) Samav Sari G.; Şahın M.T.
    Objective: Raynaud’s phenomenon (RP) is a condition characterized by vasoconstrictive attacks, and it can be diagnosed using nail-fold dermoscopy or videocapilloscopy. This study aimed to investigate the differences in nail-fold dermoscopy between patients with RP and a control group. Material and Methods: The study included 42 patients with RP and 33 individuals in the control group. Dermoscopic and clinical photographs of each finger nailfold were taken, resulting in 750 images that were categorized into 4 groups based on modified Maricq criteria: normal, suspect-capillary dilatation, abnormal-giant capillaries-hemorrhages, and unclassified. To assess the consistency of the staging, 40 random photographs were shown to 69 dermatologists who were asked to provide a rating. Results: The patient group had an underlying disease in 27 patients and the RF in these patients were evaluated as secondary RP. The nail-fold dermoscopy stages were categorized as follows: 31% stage 2, 28.6% stage 3, 28.6% stage 1, and 11.9% stage 4. The inter-observer reliability analysis was 69.56%, and the intra-observer reliability was 75.36%, with Cohen kappa >41. The study found that nail-fold dermoscopy has both inter-observer and intra-observer reliability, and it can be used for the detection of capillary abnormalities, even with minimal training. Therefore, it can be a useful technique in the early diagnosis of concomitant diseases in patients with RP. Conclusion: One notable aspect of this study was the use of a descriptive, simple ordinal score of severity to grade the overall capillaroscopic appearance. Overall, the widespread use of nail-fold dermoscopy in the diagnosis of Raynaud’s phenomenon can be a useful tool for early detection of concomitant diseases. © 2024 by Türkiye Klinikleri.