Browsing by Publisher "Palladin Institute of Biochemistry of the NASU"

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    Thermal analyses for induction sintering of powder metal compacts up to sintering temperature
    (Palladin Institute of Biochemistry of the NASU, 2014) Çavdar U.; Atik E.; Akgül M.B.; Karaca H.
    Induction sintering is developed as an alternative method to conventional sintering in order to sinter iron-based powder metal (PM) compacts. In this study, the 12 kW power and 30 kHz frequency induction-sintering machine is used for 3 wt.% copper-mixed iron. The effects of different shapes and sizes of the induction coil, and temperature differences on the PM compacts up to sintering temperature are investigated; these parameters are determined both theoretically and experimentally during induction sintering. Iron-based PM compacts are sintered at 1120°C. Induction sintering of iron-based PM compacts are simulated using a program to examine the effects of magnetic flux and temperature distribution in the sample over time. The results are compared with the experimental studies.
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    The level Pro-inflammatory and Anti-Inflammatory Biomarkers in patients with chronic mechanical low back pain under Pulse radiofrequency therapy
    (Palladin Institute of Biochemistry of the NASU, 2022) Tekin I.; Kosova F.
    Low back pain is a frequent and recurrent condition, often with a non-specific cause. Conventional treatment methods are generally insufficient in the treatment of chronic low back pain. The aim of the study was to estimate the level of IFN, IL-1, IL-6 (proinflammatory), IL-10, IL-4 (anti-inflammatory) and VEGF proteins in the serum of patients with chronic mechanical low back pain under Pulse radiofrequency (PRF) therapy. The study was carried out on 40 patients 20-60 years old, diagnosed with chronic low back pain for at least 4 months, primary complaint on lumbosacral low back pain, pain intensity VAS (visual analog scale) score of 5 and above, not responding well to conservative treatment (analgesic drugs, physiotherapy, etc.). Therapeutic Radiofrequency applications were carried out with an RF generator (RFG 3C Plus, Radionics). Blood samples were taken 1 day before interventional treatment (control), then 1 day (group1) and 15 days (group 2) after. The serum level of IFN, IL-1, IL-6, IL-10, IL-4 and VEGF l was analyzed with ELISA test. It was shown that as a result of PRF treatment the level of IL-1 was decreased while the levels of IL-4 and IL-6 were increased. It was concluded that the increase in serum levels of proinflammatory cytokines may be cor-related with the severity of pain and that the increase in the level of anti-inflammatory cytokines reduces pain by reducing inflammation. © 2022, Palladin Institute of Biochemistry of the NASU. All rights reserved.