Browsing by Subject "1,1 diphenyl 2 picrylhydrazyl"
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Item Beneficial effects of apricot-feeding on myocardial ischemia-reperfusion injury in rats(2009) Parlakpinar H.; Olmez E.; Acet A.; Ozturk F.; Tasdemir S.; Ates B.; Gul M.; Otlu A.The present study was undertaken to evaluate the cardio-protective potential of apricot-feeding in the ischemia-reperfusion (I/R) model of rats in vivo. Rats were divided into three groups of 12 rats each. Group 1 was fed with a standard rat chow, groups 2 and 3 were fed with a standard rat chow supplemented with 10% or 20% dried apricot during 3 months before the beginning of I/R studies. To produce I/R, the left main coronary artery was occluded for 30 min, followed by 120 min reperfusion, in anesthetized rats. Infarct sizes were found significantly decreased in 10% (55.0 ± 4.3%) and 20% (57.0 ± 2.9%) apricot-fed groups compared to control group (68.7 ± 2.0%). Light and electron microscopic evaluations of hearts also demonstrated similar beneficial effects on I/R injury in apricot-fed both groups. Total phenolic contents, DPPH radical scavenging and ferric-reducing power as in vitro antioxidant capacities of rat chows were significantly increased after supplementation with apricot for each ratio. Cu, Zn Superoxide dismutase (Cu, Zn SOD) and catalase (CAT) activities were increased, and lipid peroxidation was decreased significantly in the hearts of 20% apricot-fed group after I/R. In conclusion, we clearly demonstrated in vivo cardio-protective activity of apricot-feeding related to its antioxidant phenolic contents in rats subjected to myocardial I/R. © 2009 Elsevier Ltd. All rights reserved.Item Studies on the antioxidant activity of essential oil and different solvent extracts of Vitex agnus castus L. fruits from Turkey(2009) Sarikurkcu C.; Arisoy K.; Tepe B.; Cakir A.; Abali G.; Mete E.This study is designed to examine the chemical composition and antioxidant activity of the essential oil and different solvent extracts of Vitex agnus castus. GC and GC-MS analysis was resulted in the detection of 27 components, representing 94.5% of the oil. Major components of the oil were 1,8-cineole (24.98%), sabinene (13.45%), α-pinene (10.60%), α-terpinyl acetate (6.66%), and (Z)-β-farnesene (5.40%). Antioxidant activities of the samples were determined by three different test systems, DPPH, β-carotene/linoleic acid and reducing power assays. In all systems, water extract exhibited excellent activity potential than those of other extracts (hexane, dichloromethane, ethyl acetate and methanol) and the oil. As expected, amount of total phenolics was very high in this extract (112.46 ± 1.22 μg GAEs/mg extract). Dichloromethane extract has been found to be rich in flavonoids. A positive correlation was observed between the antioxidant activity potential and total phenolic and flavonoid levels of the extracts. © 2009 Elsevier Ltd. All rights reserved.Item Antimicrobial and antioxidant activities of mycelia of 10 wild mushroom species.(2010) Kalyoncu F.; Oskay M.; Saǧlam H.; Erdoǧan T.F.; Tamer A.U.Antimicrobial and antioxidant activities of mycelia obtained from 10 wild edible mushrooms-Armillaria mellea, Meripilus giganteus, Morchella costata, Morchella elata, Morchella esculenta var. vulgaris, Morchella hortensis, Morchella rotunda, Paxillus involutus, Pleurotus eryngii, and Pleurotus ostreatus-were investigated. For determination of antimicrobial activities of these mushrooms, ethanol extracts were examined with 11 test microorganisms by the agar well diffusion method. P. ostreatus and M. giganteus were the most active species against both bacteria and yeast. Antioxidant properties of ethanol extracts were studied by the 1,1-diphenyl-2-picrylhydrazyl free radical scavenging method. Among the mushroom extracts, M. elata showed the most potent radical scavenging activity. This research has shown that these 10 wild macrofungi have potential as natural antioxidants and antibiotics.Item Essential oil composition and antioxidant activity of Thymus longicaulis C. Presl subsp. longicaulis var. longicaulis(2010) Sarikurkcu C.; Sabih Ozer M.; Eskici M.; Tepe B.; Can Ş.; Mete E.This study is designed to examine the chemical composition and in vitro antioxidant activity of the hydrodistillated essential oil and various extracts obtained from Thymus longicaulis subsp. longicaulis var. longicaulis. GC and GC-MS analysis of the essential oil were resulted in determination 22 different compounds, representing 99.61% of total oil. γ-terpinene, thymol and p-cymene were determined as the major compounds of the oil (27.80, 27.65 and 19.38%, respectively). Antioxidant activities of the samples were determined by four different test systems namely β-carotene/linoleic acid, DPPH, reducing power and chelating effect. Essential oil showed the highest antioxidant activity in β-carotene/linoleic acid system among the experiments examined. In the case of other test systems, in general, methanol and water extracts exhibited the strongest activity profiles. Especially, reducing power of water extract was found superior than those of synthetic antioxidants. As well as the antioxidant activities of the extracts, they were evaluated in terms of their total phenolic and flavonoid contents. Hexane and water extracts were found to be rich-in phenolics. However, flavonoids were determined in the highest level in methanol extract. © 2010 Elsevier Ltd.Item Chemical compositions and antioxidant activities of 16 wild edible mushroom species grown in Anatolia(2012) Akata I.; Ergönül B.; Kalyoncu F.In this study, chemical compositions and antioxidant activities of 16 wild edible mushrooms (Agrocybe cylindracea, Amanita ceciliae, Armittaria mellea, Boletus reticulatus, Cantharellus cibarius, Chlorophyllum rhacodes, Coprinus comatus, Flammulina velutipes var. velutipes, Lactarius deliciosus, Lactarius salmonicolor, Pleurotus ostreatus, Polyporus squamosus, Rhizopogon roseolus, Russula anthracina, Suillus collinitus and Tricholoma myomyces) were investigated. Antioxidant properties of methanol extracts were studied by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging method. Among the mushroom extract Amanita ceciliae and Pleurotus ostreatus (96.16 %) showed the most potent radical scavenging activities at 4.51 and 2.72 mg mL -1, respectively. The lowest scavenging activity was exhibited by C. rhacodes (70.46%) at 2.35 mg mL -1. © 2012 Asian Network for Scientific Information.Item GC/MS evaluation and in vitro antioxidant activity of essential oil and solvent extracts of an endemic plant used as folk remedy in Turkey: Phlomis bourgaei boiss.(2013) Sarikurkcu C.; Sabih Ozer M.; Cakir A.; Eskici M.; Mete E.This study was outlined to examine the chemical composition of hydrodistilled essential oil and in vitro antioxidant potentials of the essential oil and different solvent extracts of endemic Phlomis bourgaei Boiss. used as folk remedy in Turkey. The chemical composition of the oil was analyzed by GC and GC-MS, and the predominant components in the oil were found to be β-caryophyllene (37.37%), (Z)-β-farnesene (15.88%), and germacrene D (10.97%). Antioxidant potentials of the solvent extracts and the oil were determined by four testing systems including β-carotene/linoleic acid, DPPH, reducing power, and chelating effect. In β-carotene/linoleic acid assay, all extracts showed the inhibition of more than 50% at all concentrations. In DPPH, chelating effect, and reducing power test systems, the water extract with 88.68%, 77.45%, and 1.857 (absorbance at 700 nm), respectively, exhibited more excellent activity potential than other extracts (hexane, ethyl acetate and methanol) and the essential oil at 1.0 mg/mL concentration. The amount of the total phenolics and flavonoids was the highest in this extract (139.50 ± 3.98 g gallic acid equivalents (GAEs)/mg extract and 22.71 ± 0.05 g quercetin equivalents (QEs)/mg extract). © 2013 Cengiz Sarikurkcu et al.