Browsing by Subject "Agent-based modeling and simulation"
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Item Agent-Based modeling and simulation of biological systems(IntechOpen, 2019) Bora, Şebnem; Emek, Sevcan; Emek, Sevcan; Fakülteler > Mühendislik Ve Doğa Bilimleri Fakültesi > Bilgisayar Mühendisliği BölümüAgent-based modeling and simulation is a powerful technique in simulating and exploring phenomena that includes a large set of active components represented by agents. The agents are actors operating in a real system, influencing the simulated environment and influenced by the simulated environment. The agents are included in the simulation model as model components performing actions autonomously and interacting with other agents and the simulated environment to represent behaviors in the real system. In this chapter, we describe how to develop an agent-based model and simulation for biological systems in Repast Simphony platform, which is a Java-based modeling system. Repast Simphony helps developers to create a scenario tree including displays of agents, grid and continuous space, data sets, data loaders, histogram, and time charts. At the end of this chapter, we present case studies developed by our research group with references to demonstrate local behavior of biological system.Item Simulation of glucose regulating mechanism with an agent-based software engineering tool(Balikesir University, 2019) Emek, Sevcan; Evren, Vedat; Bora, Şebnem; Emek, Sevcan; Fakülteler > Mühendislik Ve Doğa Bilimleri Fakültesi > Bilgisayar Mühendisliği BölümüThis study provides a detailed explanation of a regulating mechanism of the blood glucose levels by an agent-based software engineering tool. Repast Simphony which is used in implementation of this study is an agent-based software engineering tool based on the object-oriented programming using Java language. Agent-based modeling and simulation is a computational methodology for simulating and exploring phenomena that includes a large set of active components represented by agents. The agents are main components situated in space and time of agent-based simulation environment. In this study, we present hormonal regulation of blood glucose levels by our improved agent-based control mechanism. Hormonal regulation of blood glucose levels is an important process to maintain homeostasis inside the human body. We offer a negative feedback control mechanism with agent-based modeling approach to regulate the secretion of insulin hormone which is responsible for increasing the blood glucose levels. The negative feedback control mechanism run by three main agents that interact with each other to perform their local actions in the simulation environment. The result of this study shows the local behavior of the agents in the negative feedback loop and illustrates how to balance the blood glucose levels. Finally, this study which is thought a potential implementation of agent-based modeling and simulation may contribute to the exploration of other homeostatic control systems inside the human body.