Browsing by Subject "Epidemiologic Methods"

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    Epidemiological features of Turkish patients with sarcoidosis
    (2009) Musellim B.; Kumbasar O.O.; Ongen G.; Cetinkaya E.; Turker H.; Uzaslan E.; Yenturk E.; Uzun O.; Saglam L.; Celik G.; Okumus G.; Annakkaya A.N.; Altiay G.; Tabak L.; Sakar A.; Kiter G.; Erturan S.; Turktas H.; Yalniz E.; Akkoclu A.; Ogus C.; Dogan O.T.; Ozkan M.; Aktogu S.; Uzel I.
    Epidemiological characteristics of sarcoidosis differ according to geographical distribution. The aim of our study was to disclose epidemiological characteristics in our country. The data was collected from investigators, who sent information on newly-diagnosed patients via internet. In 2 years 198 female and 95 male patients were enrolled to the study (f/m:2.08). Mean age of patients was 44 ± 13 years (17-90). Mean age of male patients was 38 ± 12 while mean age of female patients was 48 ± 13 (p < 0.001). 73.4% of patients were nonsmokers (85.4% of females; 48.4% of males; (p < 0.001)). About 50% of our 293 patients were housewives. Familial sarcoidosis was found in 3 patients' first degree relatives. Estimated annual incidence of sarcoidosis for Turkey was calculated as 4 per 100,000 person. According to our study, 2/3 of sarcoidosis patients were women; mean age of patients was 45 and the disease began 10 years later in female patients. 80% of patients were nonsmokers; negative relation between sarcoidosis and smoking was evident especially in women. Familial sarcoidosis frequency was lower compared to other studies in the literature. There was no occupational exposure history in our patients. Our incidence rate, is similar with the results of other European studies. © 2008 Elsevier Ltd. All rights reserved.
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    Serum adenosine deaminase, catalase and carbonic anhydrase activities in patients with bladder cancer
    (2012) Pirinççi N.; Geçit I.; Güneş M.; Yüksel M.B.; Kaba M.; Tanik S.; Demir H.; Aslan M.
    OBJECTIVES: The relationship between adenosine deaminase and various cancers has been investigated in several studies. However, serum adenosine deaminase activity and carbonic anhydrase and catalase activities in patients with bladder cancer have not previously been reported. Therefore, the aim of this study was to measure serum adenosine deaminase, carbonic anhydrase and catalase activities in patients with bladder cancer. MATERIALS AND METHODS: Forty patients with bladder cancer and 30 healthy controls were enrolled in the study. Serum adenosine deaminase, carbonic anhydrase and catalase activities were measured spectrophotometrically. RESULTS: Serum adenosine deaminase, carbonic anhydrase and catalase activities were significantly higher in patients with bladder cancer than controls (all significant, p<0.001). CONCLUSIONS: These markers might be a potentially important finding as an additional diagnostic biochemical tool for bladder cancer. © 2012 CLINICS.